Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q3 2025 ▲▼ | Q4 2025 ▲▼ | Change ▲▼ | Q3 2025 ▲▼ | Q4 2025 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| Nuvalent Inc | 5,269,433 | 5,269,433 | 0 | $455.70M | $530.05M | 14.19% | +$74.35M |
| Revolution Medicines, Inc.(RVMD) | 6,223,291 | 6,644,403 | +421,112 | $290.63M | $529.23M | 14.17% | +$238.60M |
| Arcellx Inc COMMON STOCK | 4,649,016 | 5,724,016 | +1,075,000 | $381.68M | $373.21M | 9.99% | -$8.48M |
| Genmab A/SADS(GMAB) | 3,816,851 | 7,039,834 | +3,222,983 | $117.06M | $216.83M | 5.81% | +$99.76M |
| Tarsus Pharmaceuticals, Inc.(TARS) | 2,665,698 | 2,562,154 | -103,544 | $158.42M | $209.79M | 5.62% | +$51.37M |
| ABIVAX Société AnonymeADS(ABVX) | 1,564,196 | 1,417,473 | -146,723 | $132.80M | $191.15M | 5.12% | +$58.35M |
| Olema Pharmaceuticals, Inc.(OLMA) | 6,794,172 | 7,544,172 | +750,000 | $66.51M | $188.60M | 5.05% | +$122.09M |
| Vaxcyte, Inc.(PCVX) | 3,784,755 | 4,068,020 | +283,265 | $136.33M | $187.70M | 5.03% | +$51.37M |
| Cidara Therapeutics Inc | 961,164 | 759,565 | -201,599 | $92.04M | $167.78M | 4.49% | +$75.74M |
| Edgewise Therapeutics, Inc.(EWTX) | 6,170,131 | 6,541,210 | +371,079 | $100.08M | $162.32M | 4.35% | +$62.24M |
| Scholar Rock Holding Corporation(SRRK) | 2,009,745 | 3,062,157 | +1,052,412 | $74.84M | $134.89M | 3.61% | +$60.05M |
| UroGen Pharma Ltd.(URGN) | 4,216,084 | 4,473,648 | +257,564 | $84.11M | $104.77M | 2.81% | +$20.66M |
| Crinetics Pharmaceuticals In | 2,550,774 | 2,210,774 | -340,000 | $106.24M | $102.91M | 2.76% | -$3.33M |
| Apogee Therapeutics Inc | 1,521,757 | 1,123,243 | -398,514 | $60.46M | $84.78M | 2.27% | +$24.32M |
| EyePoint, Inc.(EYPT) | 2,005,365 | 3,691,475 | +1,686,110 | $28.56M | $67.44M | 1.81% | +$38.89M |
| Erasca, Inc.(ERAS) | 13,560,017 | 14,159,095 | +599,078 | $29.56M | $52.67M | 1.41% | +$23.11M |
| BridgeBio Pharma, Inc.(BBIO) | 684,277 | 684,277 | 0 | $35.54M | $52.34M | 1.40% | +$16.80M |
| Oruka Therapeutics, Inc.(ORKA) | 0 | 1,710,316 | +1,710,316 | $0 | $51.84M | 1.39% | +$51.84M |
| Spyre Therapeutics, Inc.(SYRE) | 1,467,266 | 1,467,266 | 0 | $24.59M | $48.07M | 1.29% | +$23.48M |
| Lexeo Therapeutics, Inc.(LXEO) | 0 | 4,763,198 | +4,763,198 | $0 | $47.30M | 1.27% | +$47.30M |
| Viridian Therapeutics, Inc.(VRDN) | 2,609,353 | 1,443,102 | -1,166,251 | $56.31M | $44.91M | 1.20% | -$11.40M |
| Ocular Therapeutix, Inc.(OCUL) | 3,497,307 | 2,935,284 | -562,023 | $40.88M | $35.63M | 0.95% | -$5.25M |
| Terns Pharmaceuticals Inc | 0 | 810,286 | +810,286 | $0 | $32.74M | 0.88% | +$32.74M |
| BridgeBio Oncology Therapeutics, Inc.(BBOT) | 1,866,141 | 2,261,749 | +395,608 | $21.61M | $28.32M | 0.76% | +$6.71M |
| Vor Biopharma Inc.(VOR) | 0 | 1,750,000 | +1,750,000 | $0 | $22.89M | 0.61% | +$22.89M |
| Assembly Biosciences Inc | 0 | 665,251 | +665,251 | $0 | $22.63M | 0.61% | +$22.63M |
| ORIC Pharmaceuticals, Inc.(ORIC) | 0 | 2,401,217 | +2,401,217 | $0 | $19.64M | 0.53% | +$19.64M |
| Inventiva S.A.ADS(IVA) | 0 | 4,000,000 | +4,000,000 | $0 | $18.60M | 0.50% | +$18.60M |
| Kalaris Therapeutics, Inc.(KLRS) | 0 | 700,000 | +700,000 | $0 | $5.91M | 0.16% | +$5.91M |
| Agios Pharmaceuticals, Inc.(AGIO) | 2,673,555 | 0 | -2,673,555 | $107.32M | $0 | — | -$107.32M |
| Alkermes plcSHS(ALKS) | 1,719,334 | 0 | -1,719,334 | $51.58M | $0 | — | -$51.58M |
| Amylyx Pharmaceuticals, Inc.(AMLX) | 1,900,000 | 0 | -1,900,000 | $25.82M | $0 | — | -$25.82M |
| Cogent Biosciences, Inc.(COGT) | 3,156,398 | 0 | -3,156,398 | $45.33M | $0 | — | -$45.33M |
| Disc Medicine, Inc.(IRON) | 247,716 | 0 | -247,716 | $16.37M | $0 | — | -$16.37M |
| Dyne Therapeutics, Inc.(DYN) | 1,898,950 | 0 | -1,898,950 | $24.02M | $0 | — | -$24.02M |
| Janux Therapeutics, Inc.(JANX) | 2,920,258 | 0 | -2,920,258 | $71.37M | $0 | — | -$71.37M |
| LENZ Therapeutics, Inc.(LENZ) | 1,073,461 | 0 | -1,073,461 | $50.00M | $0 | — | -$50.00M |
| Merus N V | 4,373,770 | 0 | -4,373,770 | $411.79M | $0 | — | -$411.79M |
| Pharvaris N V COM | 1,835,494 | 0 | -1,835,494 | $45.80M | $0 | — | -$45.80M |
| Structure Therapeutics IncADS | 372,869 | 0 | -372,869 | $10.44M | $0 | — | -$10.44M |
| Tango Therapeutics, Inc.(TNGX) | 3,086,184 | 0 | -3,086,184 | $25.92M | $0 | — | -$25.92M |