Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q4 2023 ▲▼ | Q1 2024 ▲▼ | Change ▲▼ | Q4 2023 ▲▼ | Q1 2024 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| Springworks Therapeutics Inc | 4,063,676 | 3,479,853 | -583,823 | $148.32M | $171.28M | 4.92% | +$22.95M |
| Amgen Inc.(AMGN) | 0 | 550,000 | +550,000 | $0 | $156.38M | 4.49% | +$156.38M |
| Apogee Therapeutics Inc | 2,323,456 | 2,323,456 | 0 | $64.92M | $154.39M | 4.44% | +$89.48M |
| Insmed Incorporated(INSM) | 5,350,000 | 4,783,679 | -566,321 | $165.80M | $129.78M | 3.73% | -$36.02M |
| Dyne Therapeutics, Inc.(DYN) | 2,000,000 | 4,555,383 | +2,555,383 | $26.60M | $129.33M | 3.72% | +$102.73M |
| Alnylam Pharmaceuticals, Inc.(ALNY) | 0 | 832,310 | +832,310 | $0 | $124.39M | 3.58% | +$124.39M |
| Guardant Health, Inc.(GH) | 5,000,000 | 6,000,000 | +1,000,000 | $135.25M | $123.78M | 3.56% | -$11.47M |
| argenx SEADR(ARGX) | 300,000 | 300,000 | 0 | $114.13M | $118.12M | 3.40% | +$3.99M |
| Intellia Therapeutics, Inc.(NTLA) | 2,250,000 | 4,210,784 | +1,960,784 | $68.60M | $115.84M | 3.33% | +$47.24M |
| Ocular Therapeutix, Inc.(OCUL) | 9,230,769 | 12,721,460 | +3,490,691 | $41.17M | $115.77M | 3.33% | +$74.60M |
| Dynavax Technologies Corp | 7,093,214 | 9,141,660 | +2,048,446 | $99.16M | $113.45M | 3.26% | +$14.28M |
| Axsome Therapeutics, Inc.(AXSM) | 1,000,000 | 1,304,721 | +304,721 | $79.59M | $104.12M | 2.99% | +$24.53M |
| Intra-Cellular Therapies Inc | 2,000,000 | 1,500,000 | -500,000 | $143.24M | $103.80M | 2.98% | -$39.44M |
| Geron Corporation(GERN) | 29,583,449 | 30,505,929 | +922,480 | $62.42M | $100.67M | 2.89% | +$38.25M |
| Autolus Therapeutics plcADS(AUTL) | 11,869,297 | 15,272,172 | +3,402,875 | $76.44M | $97.44M | 2.80% | +$21.00M |
| 4d Molecular Therapeutics In | 2,284,372 | 3,034,453 | +750,081 | $46.28M | $96.68M | 2.78% | +$50.40M |
| Alkermes plcSHS(ALKS) | 4,000,000 | 3,500,000 | -500,000 | $110.96M | $94.75M | 2.72% | -$16.21M |
| Bicycle Therapeutics PlcADS | 3,490,506 | 3,490,506 | 0 | $63.11M | $86.91M | 2.50% | +$23.81M |
| Pliant Therapeutics, Inc.(PLRX) | 5,750,000 | 5,750,000 | 0 | $104.13M | $85.67M | 2.46% | -$18.46M |
| Mind Medicine Mindmed Inc | 0 | 6,666,667 | +6,666,667 | $0 | $62.67M | 1.80% | +$62.67M |
| ABIVAX Société AnonymeADS(ABVX) | 4,297,438 | 4,297,438 | 0 | $45.98M | $61.45M | 1.77% | +$15.47M |
| Viridian Therapeutics, Inc.(VRDN) | 3,631,728 | 3,456,053 | -175,675 | $79.10M | $60.52M | 1.74% | -$18.58M |
| Ionis Pharmaceuticals, Inc.(IONS) | 1,249,068 | 1,373,475 | +124,407 | $63.19M | $59.54M | 1.71% | -$3.65M |
| Apellis Pharmaceuticals Inc COM | 0 | 1,000,000 | +1,000,000 | $0 | $58.78M | 1.69% | +$58.78M |
| ANI Pharmaceuticals, Inc.(ANIP) | 600,000 | 822,001 | +222,001 | $33.08M | $56.82M | 1.63% | +$23.74M |
| Travere Therapeutics, Inc.(TVTX) | 7,370,000 | 7,370,000 | 0 | $66.26M | $56.82M | 1.63% | -$9.43M |
| Verona Pharma PlcADS | 3,187,415 | 3,187,415 | 0 | $63.37M | $51.29M | 1.47% | -$12.08M |
| Kymera Therapeutics, Inc.(KYMR) | 0 | 1,262,246 | +1,262,246 | $0 | $50.74M | 1.46% | +$50.74M |
| Invivyd, Inc.(IVVD) | 0 | 10,953,937 | +10,953,937 | $0 | $48.64M | 1.40% | +$48.64M |
| Spyre Therapeutics, Inc.(SYRE) | 1,952,760 | 1,213,420 | -739,340 | $42.02M | $46.03M | 1.32% | +$4.00M |
| Nurix Therapeutics, Inc.(NRIX) | 2,997,830 | 2,997,830 | 0 | $30.94M | $44.07M | 1.27% | +$13.13M |
| Hillevax Inc | 2,900,000 | 2,572,460 | -327,540 | $46.55M | $42.78M | 1.23% | -$3.76M |
| Editas Medicine, Inc.(EDIT) | 5,473,086 | 5,527,290 | +54,204 | $55.44M | $41.01M | 1.18% | -$14.43M |
| Fate Therapeutics, Inc.(FATE) | 0 | 5,572,607 | +5,572,607 | $0 | $40.90M | 1.18% | +$40.90M |
| Terns Pharmaceuticals Inc | 6,100,000 | 6,100,000 | 0 | $39.59M | $40.02M | 1.15% | +$427.0K |
| Engene Holdings Inc COM | 0 | 2,250,000 | +2,250,000 | $0 | $38.14M | 1.10% | +$38.14M |
| Tourmaline Bio Inc | 1,815,854 | 1,595,400 | -220,454 | $47.54M | $36.53M | 1.05% | -$11.00M |
| Olema Pharmaceuticals, Inc.(OLMA) | 1,930,894 | 3,225,419 | +1,294,525 | $27.09M | $36.51M | 1.05% | +$9.42M |
| Silence Therapeutics plcADS(SLN) | 1,951,580 | 1,643,881 | -307,699 | $33.90M | $35.51M | 1.02% | +$1.61M |
| Pacific Biosciences of California, Inc.(PACB) | 7,000,000 | 7,000,000 | 0 | $68.67M | $26.25M | 0.75% | -$42.42M |
| Cybin D/B/A Helus Pharma(HELP) | 0 | 58,139,535 | +58,139,535 | $0 | $24.04M | 0.69% | +$24.04M |
| Alector Inc | 0 | 3,769,386 | +3,769,386 | $0 | $22.69M | 0.65% | +$22.69M |
| Nuvalent Inc | 450,000 | 274,512 | -175,488 | $33.12M | $20.61M | 0.59% | -$12.50M |
| Agenus Inc.(AGEN) | 31,697,539 | 31,697,539 | 0 | $26.24M | $18.38M | 0.53% | -$7.86M |
| Pyxis Oncology, Inc.(PYXS) | 0 | 4,184,100 | +4,184,100 | $0 | $17.82M | 0.51% | +$17.82M |
| Nektar Therapeutics(NKTR) | 18,400,000 | 18,400,000 | 0 | $10.40M | $17.19M | 0.49% | +$6.79M |
| Immunovant, Inc.(IMVT) | 1,000,000 | 493,352 | -506,648 | $42.13M | $15.94M | 0.46% | -$26.19M |
| Neumora Therapeutics, Inc.(NMRA) | 0 | 1,000,000 | +1,000,000 | $0 | $13.75M | 0.40% | +$13.75M |
| Repare Therapeutics Inc | 2,992,731 | 2,684,344 | -308,387 | $21.85M | $12.64M | 0.36% | -$9.20M |
| Scholar Rock Holding Corporation(SRRK) | 1,011,829 | 680,000 | -331,829 | $19.02M | $12.08M | 0.35% | -$6.95M |
| Anaptysbio Inc | 2,036,990 | 529,452 | -1,507,538 | $43.63M | $11.92M | 0.34% | -$31.71M |
| Regulus Therapeutics Inc | 0 | 3,266,566 | +3,266,566 | $0 | $9.41M | 0.27% | +$9.41M |
| Alto Neuroscience, Inc.(ANRO) | 0 | 600,000 | +600,000 | $0 | $9.21M | 0.26% | +$9.21M |
| Ultragenyx Pharmaceutical Inc.(RARE) | 0 | 167,784 | +167,784 | $0 | $7.83M | 0.23% | +$7.83M |
| Zura Bio LimitedCL A(ZURA) | 2,523,000 | 2,523,000 | 0 | $11.78M | $6.48M | 0.19% | -$5.30M |
| Allakos Inc | 2,510,736 | 5,000,000 | +2,489,264 | $6.85M | $6.30M | 0.18% | -$554.3K |
| Aligos Therapeutics Inc | 6,102,770 | 6,102,770 | 0 | $4.05M | $5.98M | 0.17% | +$1.93M |
| Relmada Therapeutics, Inc.(RLMD) | 2,044,507 | 1,240,034 | -804,473 | $8.46M | $5.77M | 0.17% | -$2.70M |
| Vigil Neuroscience Inc | 1,594,931 | 1,594,931 | 0 | $5.39M | $5.44M | 0.16% | +$47.8K |
| Metagenomi Therapeutics, Inc.(MGX) | 0 | 466,232 | +466,232 | $0 | $4.92M | 0.14% | +$4.92M |
| Syros Pharmaceuticals Inc | 828,485 | 828,485 | 0 | $6.45M | $4.43M | 0.13% | -$2.02M |
| Mersana Therapeutics Inc | 0 | 579,674 | +579,674 | $0 | $2.60M | 0.07% | +$2.60M |
| Prime Medicine, Inc.(PRME) | 0 | 303,716 | +303,716 | $0 | $2.13M | 0.06% | +$2.13M |
| Cogent Biosciences, Inc.(COGT) | 0 | 316,000 | +316,000 | $0 | $2.12M | 0.06% | +$2.12M |
| Structure Therapeutics IncADS | 300,000 | 40,137 | -259,863 | $12.23M | $1.72M | 0.05% | -$10.51M |
| Agios Pharmaceuticals, Inc.(AGIO) | 1,062,881 | 0 | -1,062,881 | $23.67M | $0 | — | -$23.67M |
| Ambrx Biopharma Inc | 3,710,412 | 0 | -3,710,412 | $52.84M | $0 | — | -$52.84M |
| Arcellx Inc COMMON STOCK | 725,145 | 0 | -725,145 | $40.25M | $0 | — | -$40.25M |
| Cytokinetics, Incorporated(CYTK) | 288,949 | 0 | -288,949 | $24.12M | $0 | — | -$24.12M |
| Edgewise Therapeutics, Inc.(EWTX) | 2,537,176 | 0 | -2,537,176 | $27.76M | $0 | — | -$27.76M |
| GH Research PLC(GHRS) | 499,400 | 0 | -499,400 | $2.90M | $0 | — | -$2.90M |
| Jazz Pharmaceuticals plcSHS USD(JAZZ) | 48,280 | 0 | -48,280 | $5.94M | $0 | — | -$5.94M |
| Orchard Therapeutics PlcADS | 2,041,670 | 0 | -2,041,670 | $33.59M | $0 | — | -$33.59M |
| Protagonist Therapeutics Inc | 275,201 | 0 | -275,201 | $6.31M | $0 | — | -$6.31M |
| Rapt Therapeutics Inc | 1,793,966 | 0 | -1,793,966 | $44.58M | $0 | — | -$44.58M |
| Sarepta Therapeutics, Inc.(SRPT) | 500,000 | 0 | -500,000 | $48.22M | $0 | — | -$48.22M |