Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q1 2024 ▲▼ | Q2 2024 ▲▼ | Change ▲▼ | Q1 2024 ▲▼ | Q2 2024 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| Amgen Inc.(AMGN) | 550,000 | 575,000 | +25,000 | $156.38M | $179.66M | 5.37% | +$23.28M |
| argenx SEADR(ARGX) | 300,000 | 400,000 | +100,000 | $118.12M | $172.02M | 5.14% | +$53.90M |
| Axsome Therapeutics, Inc.(AXSM) | 1,304,721 | 1,852,784 | +548,063 | $104.12M | $149.15M | 4.45% | +$45.03M |
| Dyne Therapeutics, Inc.(DYN) | 4,555,383 | 4,000,000 | -555,383 | $129.33M | $141.16M | 4.22% | +$11.83M |
| Springworks Therapeutics Inc | 3,479,853 | 3,700,000 | +220,147 | $171.28M | $139.38M | 4.16% | -$31.90M |
| Insmed Incorporated(INSM) | 4,783,679 | 2,000,000 | -2,783,679 | $129.78M | $134.00M | 4.00% | +$4.22M |
| Guardant Health, Inc.(GH) | 6,000,000 | 4,500,000 | -1,500,000 | $123.78M | $129.96M | 3.88% | +$6.18M |
| Dynavax Technologies Corp | 9,141,660 | 10,900,000 | +1,758,340 | $113.45M | $122.41M | 3.66% | +$8.96M |
| Alnylam Pharmaceuticals, Inc.(ALNY) | 832,310 | 500,000 | -332,310 | $124.39M | $121.50M | 3.63% | -$2.89M |
| Intellia Therapeutics, Inc.(NTLA) | 4,210,784 | 4,800,000 | +589,216 | $115.84M | $107.42M | 3.21% | -$8.41M |
| Intra-Cellular Therapies Inc | 1,500,000 | 1,537,922 | +37,922 | $103.80M | $105.33M | 3.15% | +$1.53M |
| Apellis Pharmaceuticals Inc COM | 1,000,000 | 2,500,000 | +1,500,000 | $58.78M | $95.90M | 2.86% | +$37.12M |
| Ionis Pharmaceuticals, Inc.(IONS) | 1,373,475 | 2,000,000 | +626,525 | $59.54M | $95.32M | 2.85% | +$35.78M |
| Ocular Therapeutix, Inc.(OCUL) | 12,721,460 | 12,721,460 | 0 | $115.77M | $87.01M | 2.60% | -$28.75M |
| 4d Molecular Therapeutics In | 3,034,453 | 4,061,401 | +1,026,948 | $96.68M | $85.25M | 2.55% | -$11.43M |
| Alkermes plcSHS(ALKS) | 3,500,000 | 3,500,000 | 0 | $94.75M | $84.35M | 2.52% | -$10.39M |
| Nurix Therapeutics, Inc.(NRIX) | 2,997,830 | 3,991,500 | +993,670 | $44.07M | $83.30M | 2.49% | +$39.23M |
| Immunovant, Inc.(IMVT) | 493,352 | 2,883,736 | +2,390,384 | $15.94M | $76.13M | 2.27% | +$60.19M |
| Bicycle Therapeutics PlcADS | 3,490,506 | 3,490,506 | 0 | $86.91M | $70.65M | 2.11% | -$16.27M |
| Pliant Therapeutics, Inc.(PLRX) | 5,750,000 | 5,972,257 | +222,257 | $85.67M | $64.20M | 1.92% | -$21.47M |
| Travere Therapeutics, Inc.(TVTX) | 7,370,000 | 7,370,000 | 0 | $56.82M | $60.58M | 1.81% | +$3.76M |
| Verona Pharma PlcADS | 3,187,415 | 4,000,000 | +812,585 | $51.29M | $57.84M | 1.73% | +$6.55M |
| ABIVAX Société AnonymeADS(ABVX) | 4,297,438 | 4,179,763 | -117,675 | $61.45M | $55.26M | 1.65% | -$6.20M |
| Geron Corporation(GERN) | 30,505,929 | 13,000,000 | -17,505,929 | $100.67M | $55.12M | 1.65% | -$45.55M |
| Autolus Therapeutics plcADS(AUTL) | 15,272,172 | 15,272,172 | 0 | $97.44M | $53.15M | 1.59% | -$44.29M |
| TG Therapeutics, Inc.(TGTX) | 0 | 2,870,131 | +2,870,131 | $0 | $51.06M | 1.52% | +$51.06M |
| Viridian Therapeutics, Inc.(VRDN) | 3,456,053 | 3,923,849 | +467,796 | $60.52M | $51.05M | 1.52% | -$9.47M |
| Kymera Therapeutics, Inc.(KYMR) | 1,262,246 | 1,500,000 | +237,754 | $50.74M | $44.77M | 1.34% | -$5.97M |
| Mind Medicine Mindmed Inc | 6,666,667 | 6,103,817 | -562,850 | $62.67M | $44.01M | 1.31% | -$18.66M |
| Olema Pharmaceuticals, Inc.(OLMA) | 3,225,419 | 4,000,000 | +774,581 | $36.51M | $43.28M | 1.29% | +$6.77M |
| Terns Pharmaceuticals Inc | 6,100,000 | 6,100,000 | 0 | $40.02M | $41.54M | 1.24% | +$1.52M |
| Spyre Therapeutics, Inc.(SYRE) | 1,213,420 | 1,756,667 | +543,247 | $46.03M | $41.30M | 1.23% | -$4.73M |
| Apogee Therapeutics Inc | 2,323,456 | 1,000,000 | -1,323,456 | $154.39M | $39.35M | 1.18% | -$115.04M |
| Structure Therapeutics IncADS | 40,137 | 950,000 | +909,863 | $1.72M | $37.31M | 1.11% | +$35.59M |
| ANI Pharmaceuticals, Inc.(ANIP) | 822,001 | 466,089 | -355,912 | $56.82M | $29.68M | 0.89% | -$27.14M |
| Editas Medicine, Inc.(EDIT) | 5,527,290 | 6,000,000 | +472,710 | $41.01M | $28.02M | 0.84% | -$12.99M |
| Climb Bio, Inc.(CLYM) | 0 | 3,904,785 | +3,904,785 | $0 | $27.76M | 0.83% | +$27.76M |
| Hillevax Inc | 2,572,460 | 1,832,652 | -739,808 | $42.78M | $26.50M | 0.79% | -$16.28M |
| Korro Bio, Inc.(KRRO) | 0 | 770,645 | +770,645 | $0 | $26.10M | 0.78% | +$26.10M |
| Silence Therapeutics plcADS(SLN) | 1,643,881 | 1,359,745 | -284,136 | $35.51M | $25.84M | 0.77% | -$9.67M |
| Nektar Therapeutics(NKTR) | 18,400,000 | 17,875,498 | -524,502 | $17.19M | $22.17M | 0.66% | +$4.98M |
| Engene Holdings Inc COM | 2,250,000 | 2,250,000 | 0 | $38.14M | $21.22M | 0.63% | -$16.92M |
| Alector Inc | 3,769,386 | 4,631,998 | +862,612 | $22.69M | $21.03M | 0.63% | -$1.66M |
| 89bio Inc | 0 | 2,294,011 | +2,294,011 | $0 | $18.38M | 0.55% | +$18.38M |
| Fate Therapeutics, Inc.(FATE) | 5,572,607 | 5,572,607 | 0 | $40.90M | $18.28M | 0.55% | -$22.62M |
| Inovio Pharmaceuticals, Inc.(INO) | 0 | 2,066,720 | +2,066,720 | $0 | $16.70M | 0.50% | +$16.70M |
| Praxis Precision Medicines, Inc.(PRAX) | 0 | 389,546 | +389,546 | $0 | $16.11M | 0.48% | +$16.11M |
| Cybin D/B/A Helus Pharma(HELP) | 58,139,535 | 58,139,535 | 0 | $24.04M | $15.76M | 0.47% | -$8.28M |
| Context Therapeutics Inc.(CNTX) | 0 | 7,419,355 | +7,419,355 | $0 | $14.88M | 0.44% | +$14.88M |
| Pyxis Oncology, Inc.(PYXS) | 4,184,100 | 4,184,100 | 0 | $17.82M | $13.85M | 0.41% | -$3.97M |
| Invivyd, Inc.(IVVD) | 10,953,937 | 10,953,937 | 0 | $48.64M | $12.05M | 0.36% | -$36.59M |
| Zura Bio LimitedCL A(ZURA) | 2,523,000 | 3,283,783 | +760,783 | $6.48M | $11.49M | 0.34% | +$5.01M |
| Kura Oncology, Inc.(KURA) | 0 | 384,756 | +384,756 | $0 | $7.92M | 0.24% | +$7.92M |
| Cytokinetics, Incorporated(CYTK) | 0 | 132,495 | +132,495 | $0 | $7.18M | 0.21% | +$7.18M |
| Regulus Therapeutics Inc | 3,266,566 | 3,262,564 | -4,002 | $9.41M | $5.82M | 0.17% | -$3.58M |
| Alto Neuroscience, Inc.(ANRO) | 600,000 | 511,686 | -88,314 | $9.21M | $5.47M | 0.16% | -$3.74M |
| Agenus Inc.(AGEN) | 0 | 313,359 | +313,359 | $0 | $5.25M | 0.16% | +$5.25M |
| Allakos Inc | 5,000,000 | 5,000,000 | 0 | $6.30M | $5.00M | 0.15% | -$1.30M |
| Syros Pharmaceuticals Inc | 828,485 | 828,485 | 0 | $4.43M | $4.27M | 0.13% | -$157.4K |
| Relmada Therapeutics, Inc.(RLMD) | 1,240,034 | 1,234,773 | -5,261 | $5.77M | $3.70M | 0.11% | -$2.06M |
| Edgewise Therapeutics, Inc.(EWTX) | 0 | 186,386 | +186,386 | $0 | $3.36M | 0.10% | +$3.36M |
| Scholar Rock Holding Corporation(SRRK) | 680,000 | 372,559 | -307,441 | $12.08M | $3.10M | 0.09% | -$8.97M |
| Repare Therapeutics Inc | 2,684,344 | 904,261 | -1,780,083 | $12.64M | $2.98M | 0.09% | -$9.66M |
| Cogent Biosciences, Inc.(COGT) | 316,000 | 308,235 | -7,765 | $2.12M | $2.60M | 0.08% | +$474.9K |
| Vigil Neuroscience Inc | 1,594,931 | 597,215 | -997,716 | $5.44M | $2.39M | 0.07% | -$3.05M |
| Aligos Therapeutics Inc | 6,102,770 | 6,102,770 | 0 | $5.98M | $2.14M | 0.06% | -$3.84M |
| Metagenomi Therapeutics, Inc.(MGX) | 466,232 | 466,232 | 0 | $4.92M | $1.90M | 0.06% | -$3.02M |
| Agenus Inc.(AGEN) | 31,697,539 | 0 | -31,697,539 | $18.38M | $0 | — | -$18.38M |
| Anaptysbio Inc | 529,452 | 0 | -529,452 | $11.92M | $0 | — | -$11.92M |
| Mersana Therapeutics Inc | 579,674 | 0 | -579,674 | $2.60M | $0 | — | -$2.60M |
| Neumora Therapeutics, Inc.(NMRA) | 1,000,000 | 0 | -1,000,000 | $13.75M | $0 | — | -$13.75M |
| Nuvalent Inc | 274,512 | 0 | -274,512 | $20.61M | $0 | — | -$20.61M |
| Pacific Biosciences of California, Inc.(PACB) | 7,000,000 | 0 | -7,000,000 | $26.25M | $0 | — | -$26.25M |
| Prime Medicine, Inc.(PRME) | 303,716 | 0 | -303,716 | $2.13M | $0 | — | -$2.13M |
| Tourmaline Bio Inc | 1,595,400 | 0 | -1,595,400 | $36.53M | $0 | — | -$36.53M |
| Ultragenyx Pharmaceutical Inc.(RARE) | 167,784 | 0 | -167,784 | $7.83M | $0 | — | -$7.83M |