Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q1 2026 ▲▼ | Q2 2026 ▲▼ | Change ▲▼ | Q1 2026 ▲▼ | Q2 2026 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| Guardant Health, Inc.(GH) | 3,338,241 | 3,393,312 | +55,071 | $308.35M | $509.10M | 7.50% | +$200.75M |
| Immunovant, Inc.(IMVT) | 11,526,971 | 9,341,151 | -2,185,820 | $286.33M | $359.91M | 5.30% | +$73.58M |
| STRUCTURE THERAPEUTICS INC | 4,279,848 | 4,740,072 | +460,224 | $206.29M | $254.40M | 3.75% | +$48.11M |
| Vaxcyte, Inc.(PCVX) | 4,300,000 | 4,300,000 | 0 | $249.87M | $249.96M | 3.68% | +$86.0K |
| Alnylam Pharmaceuticals, Inc.(ALNY) | 0 | 825,000 | +825,000 | $0 | $248.35M | 3.66% | +$248.35M |
| Veradermics, Incorporated(MANE) | 500,000 | 2,000,000 | +1,500,000 | $31.57M | $245.88M | 3.62% | +$214.31M |
| Tarsus Pharmaceuticals, Inc.(TARS) | 3,600,000 | 3,666,768 | +66,768 | $252.54M | $230.79M | 3.40% | -$21.75M |
| NUVALENT INC | 1,376,324 | 1,783,322 | +406,998 | $141.00M | $220.24M | 3.24% | +$79.24M |
| Alkermes plc(ALKS) | 3,590,323 | 4,000,000 | +409,677 | $126.95M | $209.58M | 3.09% | +$82.63M |
| Ocular Therapeutix, Inc.(OCUL) | 19,686,282 | 19,686,282 | 0 | $166.74M | $193.32M | 2.85% | +$26.58M |
| BioMarin Pharmaceutical Inc.(BMRN) | 1,150,000 | 3,307,481 | +2,157,481 | $64.96M | $189.25M | 2.79% | +$124.29M |
| Nurix Therapeutics, Inc.(NRIX) | 6,345,244 | 7,736,455 | +1,391,211 | $98.35M | $187.69M | 2.76% | +$89.34M |
| Oruka Therapeutics, Inc.(ORKA) | 2,034,203 | 1,926,000 | -108,203 | $99.78M | $183.30M | 2.70% | +$83.52M |
| ALUMIS INC | 6,772,595 | 6,348,558 | -424,037 | $149.20M | $178.65M | 2.63% | +$29.45M |
| Ionis Pharmaceuticals, Inc.(IONS) | 1,950,000 | 2,200,000 | +250,000 | $146.43M | $174.44M | 2.57% | +$28.01M |
| COMPASS Pathways plc(CMPS) | 12,161,496 | 12,161,496 | 0 | $67.25M | $172.09M | 2.54% | +$104.83M |
| Vera Therapeutics, Inc.(VERA) | 4,106,067 | 4,000,000 | -106,067 | $165.19M | $171.64M | 2.53% | +$6.45M |
| Axsome Therapeutics, Inc.(AXSM) | 1,100,000 | 700,000 | -400,000 | $185.92M | $171.34M | 2.52% | -$14.58M |
| Genmab A/S(GMAB) | 3,663,250 | 5,650,000 | +1,986,750 | $98.28M | $155.21M | 2.29% | +$56.92M |
| MoonLake Immunotherapeutics(MLTX) | 6,408,863 | 6,999,025 | +590,162 | $119.46M | $136.27M | 2.01% | +$16.81M |
| HEMAB THERAPEUTICS HLDGS INC | 0 | 3,602,093 | +3,602,093 | $0 | $132.30M | 1.95% | +$132.30M |
| Tango Therapeutics, Inc.(TNGX) | 2,750,000 | 4,200,000 | +1,450,000 | $57.53M | $131.29M | 1.93% | +$73.76M |
| Definium Therapeutics, Inc.(DFTX) | 3,000,000 | 2,750,000 | -250,000 | $56.70M | $129.36M | 1.91% | +$72.66M |
| GRAIL, Inc.(GRAL) | 1,722,797 | 1,834,944 | +112,147 | $89.03M | $125.27M | 1.85% | +$36.24M |
| BICARA THERAPEUTICS INC | 4,062,500 | 4,100,000 | +37,500 | $80.80M | $121.73M | 1.79% | +$40.93M |
| Maze Therapeutics, Inc.(MAZE) | 3,477,562 | 3,732,569 | +255,007 | $103.81M | $111.38M | 1.64% | +$7.57M |
| Celldex Therapeutics, Inc.(CLDX) | 1,283,979 | 2,939,151 | +1,655,172 | $40.73M | $109.37M | 1.61% | +$68.64M |
| LB Pharmaceuticals Inc(LBRX) | 3,352,804 | 3,352,804 | 0 | $82.68M | $108.82M | 1.60% | +$26.14M |
| MBX Biosciences, Inc.(MBX) | 2,757,569 | 1,732,569 | -1,025,000 | $82.31M | $95.64M | 1.41% | +$13.32M |
| GH Research PLC(GHRS) | 0 | 3,333,334 | +3,333,334 | $0 | $89.60M | 1.32% | +$89.60M |
| Cogent Biosciences, Inc.(COGT) | 1,000,000 | 2,000,000 | +1,000,000 | $38.49M | $77.40M | 1.14% | +$38.91M |
| ATAIBECKLEY INC | 12,000,000 | 14,417,442 | +2,417,442 | $42.48M | $75.98M | 1.12% | +$33.50M |
| United Therapeutics Corporation(UTHR) | 0 | 123,616 | +123,616 | $0 | $66.98M | 0.99% | +$66.98M |
| AVALO THERAPEUTICS INC | 0 | 3,610,000 | +3,610,000 | $0 | $66.71M | 0.98% | +$66.71M |
| Viridian Therapeutics, Inc.(VRDN) | 1,393,944 | 3,592,740 | +2,198,796 | $27.27M | $66.00M | 0.97% | +$38.73M |
| Cytokinetics, Incorporated(CYTK) | 1,374,320 | 700,000 | -674,320 | $90.58M | $59.63M | 0.88% | -$30.95M |
| ALTIMMUNE INC | 0 | 19,250,000 | +19,250,000 | $0 | $58.52M | 0.86% | +$58.52M |
| Personalis, Inc.(PSNL) | 3,000,000 | 4,000,000 | +1,000,000 | $19.11M | $53.60M | 0.79% | +$34.49M |
| ACLARIS THERAPEUTICS INC | 9,345,000 | 9,345,000 | 0 | $35.04M | $49.44M | 0.73% | +$14.39M |
| CORMEDIX INC | 6,274,076 | 6,274,076 | 0 | $42.60M | $49.25M | 0.73% | +$6.65M |
| GeneDx Holdings Corp.(WGS) | 0 | 700,000 | +700,000 | $0 | $48.05M | 0.71% | +$48.05M |
| Harrow, Inc.(HROW) | 0 | 969,000 | +969,000 | $0 | $41.15M | 0.61% | +$41.15M |
| Corvus Pharmaceuticals, Inc.(CRVS) | 2,491,539 | 2,491,939 | +400 | $36.45M | $37.23M | 0.55% | +$778.4K |
| SOLID BIOSCIENCES INC | 3,565,062 | 3,565,062 | 0 | $25.67M | $35.61M | 0.52% | +$9.95M |
| Beam Therapeutics Inc.(BEAM) | 820,765 | 1,000,000 | +179,235 | $19.56M | $34.32M | 0.51% | +$14.76M |
| Dyne Therapeutics, Inc.(DYN) | 2,000,000 | 1,500,000 | -500,000 | $36.26M | $33.31M | 0.49% | -$2.94M |
| IMMIX BIOPHARMA INC | 0 | 2,775,000 | +2,775,000 | $0 | $28.61M | 0.42% | +$28.61M |
| X4 PHARMACEUTICALS INC | 6,339,535 | 5,878,757 | -460,778 | $26.18M | $27.45M | 0.40% | +$1.27M |
| SHATTUCK LABS INC | 0 | 3,706,734 | +3,706,734 | $0 | $25.72M | 0.38% | +$25.72M |
| MannKind Corporation(MNKD) | 0 | 6,000,000 | +6,000,000 | $0 | $25.56M | 0.38% | +$25.56M |
| CENTURY THERAPEUTICS INC | 9,487,745 | 9,462,645 | -25,100 | $21.44M | $23.18M | 0.34% | +$1.74M |
| Generate Biomedicines, Inc.(GENB) | 0 | 1,333,815 | +1,333,815 | $0 | $22.50M | 0.33% | +$22.50M |
| VERASTEM INC | 5,740,850 | 5,740,850 | 0 | $30.43M | $21.93M | 0.32% | -$8.50M |
| Kura Oncology, Inc.(KURA) | 2,643,542 | 1,978,565 | -664,977 | $21.49M | $21.70M | 0.32% | +$212.9K |
| ENANTA PHARMACEUTICALS INC | 1,956,867 | 1,444,167 | -512,700 | $24.72M | $21.06M | 0.31% | -$3.66M |
| Nektar Therapeutics(NKTR) | 0 | 300,000 | +300,000 | $0 | $20.94M | 0.31% | +$20.94M |
| OLEMA PHARMACEUTICALS INC | 0 | 1,500,000 | +1,500,000 | $0 | $18.77M | 0.28% | +$18.77M |
| KAILERA THERAPEUTICS INC | 0 | 700,000 | +700,000 | $0 | $15.42M | 0.23% | +$15.42M |
| KARDIGAN INC | 0 | 600,000 | +600,000 | $0 | $14.31M | 0.21% | +$14.31M |
| ENLIVEN THERAPEUTICS INC | 0 | 225,000 | +225,000 | $0 | $11.42M | 0.17% | +$11.42M |
| PROMIS NEUROSCIENCES INC | 835,655 | 835,655 | 0 | $10.61M | $11.00M | 0.16% | +$384.4K |
| Immunocore Holdings plc(IMCR) | 1,931,884 | 311,218 | -1,620,666 | $58.25M | $9.88M | 0.15% | -$48.37M |
| Xencor, Inc.(XNCR) | 0 | 593,551 | +593,551 | $0 | $9.56M | 0.14% | +$9.56M |
| CONTEXT THERAPEUTICS INC | 7,419,355 | 7,419,355 | 0 | $19.44M | $4.11M | 0.06% | -$15.33M |
| INVENTIVA SA | 1,222,453 | 800,000 | -422,453 | $6.78M | $3.02M | 0.04% | -$3.76M |
| ALIGOS THERAPEUTICS INC | 444,110 | 444,110 | 0 | $3.30M | $2.56M | 0.04% | -$737.2K |
| ANI Pharmaceuticals, Inc.(ANIP) | 600,000 | 0 | -600,000 | $46.14M | $0 | — | -$46.14M |
| APELLIS PHARMACEUTICALS INC COM | 4,532,374 | 0 | -4,532,374 | $182.34M | $0 | — | -$182.34M |
| APOGEE THERAPEUTICS INC | 285,000 | 0 | -285,000 | $23.99M | $0 | — | -$23.99M |
| BILLIONTOONE INC | 50,000 | 0 | -50,000 | $3.95M | $0 | — | -$3.95M |
| BridgeBio Pharma, Inc.(BBIO) | 841,445 | 0 | -841,445 | $62.49M | $0 | — | -$62.49M |
| CENTESSA PHARMACEUTICALS PLC | 3,158,041 | 0 | -3,158,041 | $125.44M | $0 | — | -$125.44M |
| CRESCENT BIOPHARMA INC. | 453,686 | 0 | -453,686 | $8.33M | $0 | — | -$8.33M |
| CYBIN INC | 1,313,137 | 0 | -1,313,137 | $6.30M | $0 | — | -$6.30M |
| ENGENE HOLDINGS INC COM | 4,377,572 | 0 | -4,377,572 | $29.81M | $0 | — | -$29.81M |
| GERON CORP | 31,720,278 | 0 | -31,720,278 | $47.26M | $0 | — | -$47.26M |
| Janux Therapeutics, Inc.(JANX) | 1,187,290 | 0 | -1,187,290 | $16.50M | $0 | — | -$16.50M |
| LARIMAR THERAPEUTICS INC | 1,500,000 | 0 | -1,500,000 | $6.75M | $0 | — | -$6.75M |
| SOLENO THERAPEUTICS INC | 1,078,710 | 0 | -1,078,710 | $36.12M | $0 | — | -$36.12M |
| TERNS PHARMACEUTICALS INC | 1,073,877 | 0 | -1,073,877 | $56.61M | $0 | — | -$56.61M |