Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q4 2025 ▲▼ | Q1 2026 ▲▼ | Change ▲▼ | Q4 2025 ▲▼ | Q1 2026 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| Mirum Pharmaceuticals, Inc.(MIRM) | 6,795,121 | 7,679,684 | +884,563 | $536.75M | $709.45M | 18.25% | +$172.70M |
| Newamsterdam Pharma Company ORDINARY SHARES | 16,943,774 | 16,943,774 | 0 | $594.39M | $542.37M | 13.96% | -$52.02M |
| Erasca, Inc.(ERAS) | 22,729,436 | 24,675,188 | +1,945,752 | $84.55M | $399.24M | 10.27% | +$314.69M |
| BridgeBio Pharma, Inc.(BBIO) | 3,545,557 | 3,448,139 | -97,418 | $271.20M | $256.06M | 6.59% | -$15.14M |
| Arcutis Biotherapeutics, Inc.(ARQT) | 9,874,511 | 9,874,511 | 0 | $286.76M | $232.64M | 5.99% | -$54.11M |
| MBX Biosciences, Inc.(MBX) | 6,652,013 | 6,652,013 | 0 | $209.80M | $198.56M | 5.11% | -$11.24M |
| Phathom Pharmaceuticals, Inc.(PHAT) | 12,466,489 | 12,466,489 | 0 | $206.82M | $138.50M | 3.56% | -$68.32M |
| Maze Therapeutics, Inc.(MAZE) | 4,567,274 | 4,567,274 | 0 | $189.22M | $136.33M | 3.51% | -$52.89M |
| Krystal Biotech, Inc.(KRYS) | 488,460 | 481,307 | -7,153 | $120.42M | $124.33M | 3.20% | +$3.91M |
| Trevi Therapeutics, Inc.(TRVI) | 10,259,409 | 9,939,547 | -319,862 | $128.45M | $118.58M | 3.05% | -$9.87M |
| Palvella Therapeutics, Inc.(PVLA) | 722,400 | 882,400 | +160,000 | $75.61M | $109.99M | 2.83% | +$34.38M |
| Kalvista Pharmaceuticals Inc | 5,039,867 | 4,961,108 | -78,759 | $81.39M | $99.87M | 2.57% | +$18.47M |
| Disc Medicine, Inc.(IRON) | 1,260,000 | 1,354,852 | +94,852 | $100.06M | $86.63M | 2.23% | -$13.43M |
| Cytokinetics, Incorporated(CYTK) | 934,642 | 1,159,879 | +225,237 | $59.39M | $76.45M | 1.97% | +$17.06M |
| Revolution Medicines, Inc.(RVMD) | 797,455 | 675,686 | -121,769 | $63.52M | $65.71M | 1.69% | +$2.19M |
| Dyne Therapeutics, Inc.(DYN) | 3,153,082 | 3,153,082 | 0 | $61.67M | $57.17M | 1.47% | -$4.51M |
| Savara Inc.(SVRA) | 9,862,301 | 9,720,852 | -141,449 | $59.47M | $53.08M | 1.37% | -$6.39M |
| Tarsus Pharmaceuticals, Inc.(TARS) | 728,644 | 728,644 | 0 | $59.66M | $51.11M | 1.32% | -$8.55M |
| Vor Biopharma Inc.(VOR) | 2,543,939 | 2,543,939 | 0 | $33.27M | $45.38M | 1.17% | +$12.11M |
| Agios Pharmaceuticals, Inc.(AGIO) | 1,279,754 | 1,256,080 | -23,674 | $34.83M | $42.49M | 1.09% | +$7.66M |
| BioCryst Pharmaceuticals, Inc.(BCRX) | 0 | 4,009,240 | +4,009,240 | $0 | $38.17M | 0.98% | +$38.17M |
| Zai Lab LimitedADR(ZLAB) | 1,902,320 | 1,902,320 | 0 | $33.56M | $35.78M | 0.92% | +$2.23M |
| Aura Biosciences, Inc.(AURA) | 5,100,000 | 5,100,000 | 0 | $27.80M | $34.12M | 0.88% | +$6.32M |
| Acadia Pharmaceuticals Inc | 1,297,198 | 1,438,198 | +141,000 | $34.65M | $32.01M | 0.82% | -$2.63M |
| Ascendis Pharma A/SADR(ASND) | 133,333 | 133,333 | 0 | $28.43M | $30.50M | 0.78% | +$2.07M |
| Lexeo Therapeutics, Inc.(LXEO) | 4,424,725 | 4,424,725 | 0 | $43.94M | $25.40M | 0.65% | -$18.54M |
| Alkermes plcSHS(ALKS) | 700,647 | 700,647 | 0 | $19.60M | $24.77M | 0.64% | +$5.17M |
| Aclaris Therapeutics, Inc.(ACRS) | 0 | 4,925,374 | +4,925,374 | $0 | $18.47M | 0.48% | +$18.47M |
| Monte Rosa Therapeutics, Inc.(GLUE) | 0 | 1,000,000 | +1,000,000 | $0 | $16.45M | 0.42% | +$16.45M |
| Immunocore Holdings plcADS(IMCR) | 384,782 | 484,782 | +100,000 | $13.36M | $14.62M | 0.38% | +$1.26M |
| MannKind Corporation(MNKD) | 4,225,000 | 5,900,000 | +1,675,000 | $23.96M | $14.46M | 0.37% | -$9.50M |
| Valneva SEADS(VALN) | 2,291,666 | 2,291,666 | 0 | $20.21M | $14.32M | 0.37% | -$5.89M |
| Evolus, Inc.(EOLS) | 2,630,665 | 2,630,665 | 0 | $17.49M | $10.81M | 0.28% | -$6.68M |
| Newamsterdam Pharma CompanyW EXP 99 99 999 *W EXP 99/99/999 | 500,333 | 500,333 | 0 | $11.51M | $10.03M | 0.26% | -$1.48M |
| Allogene Therapeutics Inc | 3,868,750 | 3,796,668 | -72,082 | $5.30M | $9.26M | 0.24% | +$3.96M |
| Autolus Therapeutics plcADS(AUTL) | 4,623,324 | 4,447,910 | -175,414 | $9.20M | $6.14M | 0.16% | -$3.06M |
| iBio, Inc.(IBIO) | 1,953,467 | 1,953,467 | 0 | $3.77M | $3.71M | 0.10% | -$58.6K |
| Xilio Therapeutics, Inc.(XLO) | 0 | 422,505 | +422,505 | $0 | $3.55M | 0.09% | +$3.55M |
| ABIVAX Société AnonymeADS(ABVX) | 378,300 | 0 | -378,300 | $51.02M | $0 | — | -$51.02M |
| Avidity Biosciences Inc | 983,125 | 0 | -983,125 | $70.91M | $0 | — | -$70.91M |
| Design Therapeutics, Inc.(DSGN) | 521,000 | 0 | -521,000 | $4.89M | $0 | — | -$4.89M |
| Rapt Therapeutics Inc | 983,333 | 0 | -983,333 | $33.31M | $0 | — | -$33.31M |
| Travere Therapeutics, Inc.(TVTX) | 241,592 | 0 | -241,592 | $9.23M | $0 | — | -$9.23M |
| Xilio Therapeutics, Inc.(XLO) | 5,915,091 | 0 | -5,915,091 | $3.79M | $0 | — | -$3.79M |