Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q1 2025 ▲▼ | Q2 2025 ▲▼ | Change ▲▼ | Q1 2025 ▲▼ | Q2 2025 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| Mirum Pharmaceuticals, Inc.(MIRM) | 6,795,121 | 6,795,121 | 0 | $306.12M | $345.80M | 13.83% | +$39.68M |
| Verona Pharma PlcADS | 3,457,850 | 3,383,950 | -73,900 | $219.54M | $320.05M | 12.80% | +$100.52M |
| Newamsterdam Pharma Company ORDINARY SHARES | 16,116,418 | 16,607,074 | +490,656 | $329.90M | $300.75M | 12.03% | -$29.15M |
| BridgeBio Pharma, Inc.(BBIO) | 3,800,457 | 3,800,457 | 0 | $131.38M | $164.10M | 6.56% | +$32.72M |
| Arcutis Biotherapeutics, Inc.(ARQT) | 8,785,284 | 9,874,511 | +1,089,227 | $137.40M | $138.44M | 5.54% | +$1.04M |
| Phathom Pharmaceuticals, Inc.(PHAT) | 10,109,279 | 12,466,489 | +2,357,210 | $63.39M | $119.55M | 4.78% | +$56.17M |
| Krystal Biotech, Inc.(KRYS) | 688,460 | 688,460 | 0 | $124.13M | $94.64M | 3.78% | -$29.49M |
| Disc Medicine, Inc.(IRON) | 1,754,834 | 1,654,834 | -100,000 | $87.11M | $87.64M | 3.50% | +$530.0K |
| MBX Biosciences, Inc.(MBX) | 5,985,347 | 5,985,347 | 0 | $44.17M | $68.29M | 2.73% | +$24.12M |
| Tarsus Pharmaceuticals, Inc.(TARS) | 1,397,527 | 1,397,527 | 0 | $71.79M | $56.61M | 2.26% | -$15.18M |
| Trevi Therapeutics, Inc.(TRVI) | 10,259,409 | 10,259,409 | 0 | $64.53M | $56.12M | 2.24% | -$8.41M |
| Maze Therapeutics, Inc.(MAZE) | 4,129,001 | 4,567,275 | +438,274 | $45.46M | $56.04M | 2.24% | +$10.58M |
| Kalvista Pharmaceuticals Inc | 4,887,867 | 4,887,867 | 0 | $56.41M | $55.26M | 2.21% | -$1.15M |
| Zai Lab LimitedADR(ZLAB) | 350,000 | 1,308,138 | +958,138 | $12.65M | $45.75M | 1.83% | +$33.10M |
| Agios Pharmaceuticals, Inc.(AGIO) | 1,069,854 | 1,279,754 | +209,900 | $31.35M | $42.56M | 1.70% | +$11.22M |
| Revolution Medicines, Inc.(RVMD) | 997,455 | 997,455 | 0 | $35.27M | $36.70M | 1.47% | +$1.43M |
| Ultragenyx Pharmaceutical Inc.(RARE) | 658,715 | 983,715 | +325,000 | $23.85M | $35.77M | 1.43% | +$11.92M |
| Aura Biosciences, Inc.(AURA) | 0 | 5,100,000 | +5,100,000 | $0 | $31.93M | 1.28% | +$31.93M |
| Erasca, Inc.(ERAS) | 22,575,851 | 22,729,436 | +153,585 | $30.93M | $28.87M | 1.15% | -$2.06M |
| Alkermes plcSHS(ALKS) | 601,129 | 1,000,647 | +399,518 | $19.85M | $28.63M | 1.14% | +$8.78M |
| Savara Inc.(SVRA) | 11,462,301 | 11,462,301 | 0 | $31.75M | $26.13M | 1.05% | -$5.62M |
| Mereo BioPharma Group plcADS(MREO) | 7,819,863 | 9,440,112 | +1,620,249 | $17.59M | $25.58M | 1.02% | +$7.99M |
| Ascendis Pharma A/SADR(ASND) | 133,333 | 133,333 | 0 | $20.78M | $23.01M | 0.92% | +$2.23M |
| Evolus, Inc.(EOLS) | 0 | 2,435,550 | +2,435,550 | $0 | $22.43M | 0.90% | +$22.43M |
| Hillevax Inc | 10,617,062 | 10,617,062 | 0 | $15.39M | $21.13M | 0.84% | +$5.73M |
| CG Oncology, Inc.(CGON) | 770,000 | 770,000 | 0 | $18.86M | $20.02M | 0.80% | +$1.16M |
| Akero Therapeutics Inc | 0 | 366,784 | +366,784 | $0 | $19.57M | 0.78% | +$19.57M |
| Cytokinetics, Incorporated(CYTK) | 0 | 554,731 | +554,731 | $0 | $18.33M | 0.73% | +$18.33M |
| Lexeo Therapeutics, Inc.(LXEO) | 955,515 | 4,424,725 | +3,469,210 | $3.32M | $17.79M | 0.71% | +$14.47M |
| Avidity Biosciences Inc | 525,000 | 625,000 | +100,000 | $15.50M | $17.75M | 0.71% | +$2.25M |
| Jade Biosciences Inc | 0 | 1,772,116 | +1,772,116 | $0 | $17.70M | 0.71% | +$17.70M |
| Palvella Therapeutics, Inc.(PVLA) | 690,012 | 722,400 | +32,388 | $19.31M | $16.28M | 0.65% | -$3.03M |
| Vaxcyte, Inc.(PCVX) | 539,405 | 474,405 | -65,000 | $20.37M | $15.42M | 0.62% | -$4.95M |
| Travere Therapeutics, Inc.(TVTX) | 0 | 1,002,092 | +1,002,092 | $0 | $14.83M | 0.59% | +$14.83M |
| Dyne Therapeutics, Inc.(DYN) | 1,443,341 | 1,505,984 | +62,643 | $15.10M | $14.34M | 0.57% | -$760.4K |
| Cogent Biosciences, Inc.(COGT) | 936,576 | 1,734,601 | +798,025 | $5.61M | $12.45M | 0.50% | +$6.84M |
| Immunocore Holdings plcADS(IMCR) | 301,170 | 384,782 | +83,612 | $8.94M | $12.07M | 0.48% | +$3.14M |
| ORIC Pharmaceuticals, Inc.(ORIC) | 1,410,193 | 1,065,334 | -344,859 | $7.87M | $10.81M | 0.43% | +$2.94M |
| Autolus Therapeutics plcADS(AUTL) | 4,623,324 | 4,623,324 | 0 | $7.17M | $10.54M | 0.42% | +$3.38M |
| Valneva SEADS(VALN) | 0 | 1,458,333 | +1,458,333 | $0 | $8.24M | 0.33% | +$8.24M |
| Crescent Biopharma, Inc.(CBIO) | 0 | 453,685 | +453,685 | $0 | $7.32M | 0.29% | +$7.32M |
| Design Therapeutics, Inc.(DSGN) | 1,953,547 | 1,953,547 | 0 | $7.54M | $6.58M | 0.26% | -$957.2K |
| Oruka Therapeutics, Inc.(ORKA) | 583,327 | 583,327 | 0 | $5.98M | $6.54M | 0.26% | +$554.2K |
| Silence Therapeutics plcADS(SLN) | 1,148,591 | 970,130 | -178,461 | $3.24M | $5.63M | 0.23% | +$2.39M |
| Allogene Therapeutics Inc | 3,868,750 | 3,868,750 | 0 | $5.65M | $4.37M | 0.17% | -$1.28M |
| Newamsterdam Pharma CompanyW EXP 99 99 999 *W EXP 99/99/999 | 500,333 | 500,333 | 0 | $4.50M | $4.00M | 0.16% | -$495.3K |
| MacroGenics, Inc.(MGNX) | 3,175,665 | 3,175,665 | 0 | $4.03M | $3.84M | 0.15% | -$190.5K |
| Adverum Biotechnologies Inc | 1,069,244 | 1,069,244 | 0 | $4.67M | $2.30M | 0.09% | -$2.37M |
| Elevation Oncology Inc | 5,993,579 | 5,993,579 | 0 | $1.55M | $2.20M | 0.09% | +$647.3K |
| Acadia Pharmaceuticals Inc | 470,338 | 0 | -470,338 | $7.81M | $0 | — | -$7.81M |
| Immatics N.V.SHS(IMTX) | 1,247,911 | 0 | -1,247,911 | $5.63M | $0 | — | -$5.63M |
| Merus N V | 373,100 | 0 | -373,100 | $15.70M | $0 | — | -$15.70M |
| Rhythm Pharmaceuticals, Inc.(RYTM) | 678,760 | 0 | -678,760 | $35.95M | $0 | — | -$35.95M |
| Rocket Pharmaceuticals, Inc.(RCKT) | 1,079,025 | 0 | -1,079,025 | $7.20M | $0 | — | -$7.20M |
| Soleno Therapeutics Inc | 499,159 | 0 | -499,159 | $35.66M | $0 | — | -$35.66M |