Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q3 2024 ▲▼ | Q4 2024 ▲▼ | Change ▲▼ | Q3 2024 ▲▼ | Q4 2024 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| Newamsterdam Pharma Company ORDINARY SHARES | 12,855,194 | 15,916,418 | +3,061,224 | $213.40M | $409.05M | 16.98% | +$195.66M |
| Mirum Pharmaceuticals, Inc.(MIRM) | 6,570,392 | 6,570,392 | 0 | $256.25M | $271.69M | 11.28% | +$15.44M |
| Verona Pharma PlcADS | 3,383,950 | 3,383,950 | 0 | $97.36M | $157.15M | 6.52% | +$59.79M |
| Krystal Biotech, Inc.(KRYS) | 988,460 | 788,460 | -200,000 | $179.93M | $123.52M | 5.13% | -$56.41M |
| Arcutis Biotherapeutics, Inc.(ARQT) | 8,785,284 | 8,785,284 | 0 | $81.70M | $122.38M | 5.08% | +$40.68M |
| Disc Medicine, Inc.(IRON) | 1,754,834 | 1,754,834 | 0 | $86.23M | $111.26M | 4.62% | +$25.02M |
| MBX Biosciences, Inc.(MBX) | 5,985,347 | 5,985,347 | 0 | $155.50M | $110.31M | 4.58% | -$45.19M |
| Rhythm Pharmaceuticals, Inc.(RYTM) | 2,416,952 | 1,869,808 | -547,144 | $126.62M | $104.67M | 4.34% | -$21.95M |
| BridgeBio Pharma, Inc.(BBIO) | 3,760,457 | 3,800,457 | +40,000 | $95.74M | $104.28M | 4.33% | +$8.54M |
| Tarsus Pharmaceuticals, Inc.(TARS) | 1,587,527 | 1,587,527 | 0 | $52.21M | $87.90M | 3.65% | +$35.69M |
| Phathom Pharmaceuticals, Inc.(PHAT) | 10,109,279 | 10,109,279 | 0 | $182.78M | $82.09M | 3.41% | -$100.69M |
| Erasca, Inc.(ERAS) | 19,391,687 | 19,391,687 | 0 | $52.94M | $48.67M | 2.02% | -$4.27M |
| Vaxcyte, Inc.(PCVX) | 879,405 | 539,405 | -340,000 | $100.49M | $44.16M | 1.83% | -$56.33M |
| Trevi Therapeutics, Inc.(TRVI) | 7,381,090 | 10,664,774 | +3,283,684 | $24.65M | $43.94M | 1.82% | +$19.29M |
| Revolution Medicines, Inc.(RVMD) | 997,455 | 997,455 | 0 | $45.23M | $43.63M | 1.81% | -$1.61M |
| Kalvista Pharmaceuticals Inc | 3,687,867 | 4,887,867 | +1,200,000 | $42.71M | $41.40M | 1.72% | -$1.31M |
| Agios Pharmaceuticals, Inc.(AGIO) | 1,044,154 | 1,069,754 | +25,600 | $46.39M | $35.15M | 1.46% | -$11.24M |
| Edgewise Therapeutics, Inc.(EWTX) | 2,832,867 | 1,271,245 | -1,561,622 | $75.61M | $33.94M | 1.41% | -$41.67M |
| Soleno Therapeutics Inc | 875,667 | 699,159 | -176,508 | $44.21M | $31.43M | 1.30% | -$12.79M |
| ORIC Pharmaceuticals, Inc.(ORIC) | 4,142,855 | 3,888,238 | -254,617 | $42.46M | $31.38M | 1.30% | -$11.09M |
| Ultragenyx Pharmaceutical Inc.(RARE) | 633,715 | 658,715 | +25,000 | $35.20M | $27.71M | 1.15% | -$7.49M |
| Savara Inc.(SVRA) | 8,157,385 | 8,660,379 | +502,994 | $34.59M | $26.59M | 1.10% | -$8.00M |
| CG Oncology, Inc.(CGON) | 770,000 | 770,000 | 0 | $29.05M | $22.08M | 0.92% | -$6.97M |
| Hillevax Inc | 10,617,062 | 10,617,062 | 0 | $18.69M | $21.98M | 0.91% | +$3.29M |
| Anaptysbio Inc | 2,209,189 | 1,573,719 | -635,470 | $74.01M | $20.84M | 0.86% | -$53.17M |
| Rocket Pharmaceuticals, Inc.(RCKT) | 1,485,630 | 1,479,025 | -6,605 | $27.44M | $18.59M | 0.77% | -$8.85M |
| Ascendis Pharma A/SADR(ASND) | 133,333 | 133,333 | 0 | $19.91M | $18.36M | 0.76% | -$1.55M |
| Mereo BioPharma Group plcADS(MREO) | 5,097,779 | 5,097,779 | 0 | $20.95M | $17.84M | 0.74% | -$3.11M |
| Alkermes plcSHS(ALKS) | 576,129 | 601,129 | +25,000 | $16.13M | $17.29M | 0.72% | +$1.16M |
| Merus N V | 373,100 | 373,100 | 0 | $18.64M | $15.69M | 0.65% | -$2.95M |
| Immatics N.V.SHS(IMTX) | 1,354,711 | 2,147,911 | +793,200 | $15.46M | $15.27M | 0.63% | -$185.6K |
| Pliant Therapeutics, Inc.(PLRX) | 0 | 1,120,803 | +1,120,803 | $0 | $14.76M | 0.61% | +$14.76M |
| Design Therapeutics, Inc.(DSGN) | 1,892,547 | 1,953,547 | +61,000 | $10.18M | $12.05M | 0.50% | +$1.87M |
| Oruka Therapeutics, Inc.(ORKA) | 477,327 | 583,327 | +106,000 | $11.70M | $11.31M | 0.47% | -$388.6K |
| Autolus Therapeutics plcADS(AUTL) | 4,623,324 | 4,623,324 | 0 | $16.78M | $10.86M | 0.45% | -$5.92M |
| MacroGenics, Inc.(MGNX) | 3,010,727 | 3,175,665 | +164,938 | $9.91M | $10.32M | 0.43% | +$415.6K |
| Day One Biopharmaceuticals I COM | 689,655 | 689,655 | 0 | $9.61M | $8.74M | 0.36% | -$869.0K |
| Acadia Pharmaceuticals Inc | 470,338 | 470,338 | 0 | $7.23M | $8.63M | 0.36% | +$1.40M |
| Silence Therapeutics plcADS(SLN) | 1,148,591 | 1,148,591 | 0 | $20.88M | $7.90M | 0.33% | -$12.98M |
| Palvella Therapeutics, Inc.(PVLA) | 0 | 653,892 | +653,892 | $0 | $7.85M | 0.33% | +$7.85M |
| 89bio Inc | 1,000,000 | 1,000,000 | 0 | $7.40M | $7.82M | 0.32% | +$420.0K |
| Cogent Biosciences, Inc.(COGT) | 936,576 | 936,576 | 0 | $10.12M | $7.31M | 0.30% | -$2.81M |
| Newamsterdam Pharma CompanyW EXP 99 99 999 *W EXP 99/99/999 | 500,333 | 500,333 | 0 | $3.50M | $7.13M | 0.30% | +$3.63M |
| Lexeo Therapeutics, Inc.(LXEO) | 1,250,786 | 955,515 | -295,271 | $11.31M | $6.29M | 0.26% | -$5.02M |
| Allogene Therapeutics Inc | 2,867,750 | 2,867,750 | 0 | $8.03M | $6.11M | 0.25% | -$1.92M |
| Arvinas, Inc.(ARVN) | 285,331 | 285,331 | 0 | $7.03M | $5.47M | 0.23% | -$1.56M |
| Adverum Biotechnologies Inc | 1,069,244 | 1,069,244 | 0 | $7.51M | $4.99M | 0.21% | -$2.51M |
| Eledon Pharmaceuticals, Inc.(ELDN) | 0 | 1,176,735 | +1,176,735 | $0 | $4.85M | 0.20% | +$4.85M |
| Elevation Oncology Inc | 5,993,579 | 5,993,579 | 0 | $3.60M | $3.37M | 0.14% | -$223.6K |
| Immunocore Holdings plcADS(IMCR) | 108,762 | 108,762 | 0 | $3.39M | $3.21M | 0.13% | -$177.3K |
| Aclaris Therapeutics, Inc.(ACRS) | 264,377 | 0 | -264,377 | $304.0K | $0 | — | -$304.0K |
| Nuvation Bio Inc.CL A(NUVB) | 1,218,236 | 0 | -1,218,236 | $2.79M | $0 | — | -$2.79M |
| PepGen Inc.(PEPG) | 702,694 | 0 | -702,694 | $6.01M | $0 | — | -$6.01M |
| Pieris Pharmaceuticals Inc | 15,942 | 0 | -15,942 | $266.9K | $0 | — | -$266.9K |
| Puma Biotechnology, Inc.(PBYI) | 3,062,558 | 0 | -3,062,558 | $7.81M | $0 | — | -$7.81M |
| Tyra Biosciences, Inc.(TYRA) | 731,020 | 0 | -731,020 | $17.19M | $0 | — | -$17.19M |