Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q4 2025 ▲▼ | Q1 2026 ▲▼ | Change ▲▼ | Q4 2025 ▲▼ | Q1 2026 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| Caris Life Sciences, Inc.(CAI) | 7,816,142 | 8,009,447 | +193,305 | $210.88M | $143.21M | 4.78% | -$67.67M |
| Guardant Health, Inc.DEBT 1 250 2 1(GH) | 0 | 0 | 0 | $192.31M | $102.58M | 3.42% | -$89.74M |
| Repligen CorporationNOTE 1 000 12 1(RGEN) | 0 | 0 | 0 | $110.85M | $98.68M | 3.29% | -$12.17M |
| NeoGenomics, Inc.NOTE 0 250 1 1(NEO) | 0 | 0 | 0 | $89.72M | $91.85M | 3.06% | +$2.13M |
| Neurocrine Biosciences, Inc.(NBIX) | 751,534 | 652,121 | -99,413 | $106.59M | $85.91M | 2.87% | -$20.68M |
| Glaukos Corporation(GKOS) | 921,979 | 763,505 | -158,474 | $104.10M | $82.20M | 2.74% | -$21.90M |
| Centessa Pharmaceuticals PlcADS | 2,188,320 | 1,986,768 | -201,552 | $54.73M | $78.91M | 2.63% | +$24.18M |
| Xenon Pharmaceuticals Inc.(XENE) | 1,825,076 | 1,338,452 | -486,624 | $81.80M | $77.83M | 2.60% | -$3.97M |
| Dianthus Therapeutics, Inc.(DNTH) | 1,273,935 | 899,364 | -374,571 | $52.50M | $75.47M | 2.52% | +$22.98M |
| Edgewise Therapeutics, Inc.(EWTX) | 5,210,831 | 2,347,583 | -2,863,248 | $129.31M | $73.95M | 2.47% | -$55.36M |
| iRhythm Holdings, Inc.(IRTC) | 217,345 | 610,192 | +392,847 | $38.57M | $72.01M | 2.40% | +$33.45M |
| Nuvalent Inc | 821,406 | 700,429 | -120,977 | $82.63M | $71.76M | 2.39% | -$10.87M |
| Kodiak Sciences Inc.(KOD) | 2,072,788 | 1,818,665 | -254,123 | $57.96M | $69.33M | 2.31% | +$11.37M |
| CG Oncology, Inc.(CGON) | 1,870,571 | 984,783 | -885,788 | $77.67M | $66.65M | 2.22% | -$11.02M |
| Alphatec Holdings, Inc.NOTE 0 750 3 1(ATEC) | 0 | 0 | 0 | $0 | $63.39M | 2.11% | +$63.39M |
| argenx SEADR(ARGX) | 31,007 | 84,939 | +53,932 | $26.08M | $62.03M | 2.07% | +$35.95M |
| Hinge Health, Inc.CL A(HNGE) | 1,304,623 | 1,455,123 | +150,500 | $60.60M | $56.11M | 1.87% | -$4.49M |
| Acadia Pharmaceuticals Inc | 2,032,021 | 2,471,199 | +439,178 | $54.28M | $55.01M | 1.84% | +$733.6K |
| Monte Rosa Therapeutics, Inc.(GLUE) | 948,316 | 3,206,574 | +2,258,258 | $14.87M | $52.75M | 1.76% | +$37.88M |
| Krystal Biotech, Inc.(KRYS) | 202,101 | 182,425 | -19,676 | $49.83M | $47.12M | 1.57% | -$2.70M |
| Spyre Therapeutics, Inc.(SYRE) | 1,634,615 | 932,823 | -701,792 | $53.55M | $47.05M | 1.57% | -$6.50M |
| Guardant Health, Inc.(GH) | 0 | 499,712 | +499,712 | $0 | $46.16M | 1.54% | +$46.16M |
| Thermo Fisher Scientific Inc.(TMO) | 80,725 | 92,915 | +12,190 | $46.78M | $45.67M | 1.52% | -$1.11M |
| Generate Biomedicines, Inc.(GENB) | 0 | 3,592,999 | +3,592,999 | $0 | $44.91M | 1.50% | +$44.91M |
| MBX Biosciences, Inc.(MBX) | 1,018,600 | 1,492,467 | +473,867 | $32.13M | $44.55M | 1.49% | +$12.42M |
| BrightSpring Health Services, Inc.(BTSG) | 1,195,786 | 1,016,562 | -179,224 | $44.78M | $43.32M | 1.44% | -$1.47M |
| Celldex Therapeutics, Inc.(CLDX) | 1,858,109 | 1,356,082 | -502,027 | $50.47M | $43.01M | 1.43% | -$7.45M |
| NeoGenomics, Inc.(NEO) | 4,632,801 | 5,617,402 | +984,601 | $54.48M | $41.68M | 1.39% | -$12.80M |
| Apogee Therapeutics Inc | 575,067 | 478,667 | -96,400 | $43.41M | $40.29M | 1.34% | -$3.12M |
| Bright Minds Biosciences Inc.(DRUG) | 324,358 | 539,708 | +215,350 | $25.31M | $39.38M | 1.31% | +$14.07M |
| CareDx, Inc.(CDNA) | 1,585,220 | 2,173,146 | +587,926 | $29.87M | $37.73M | 1.26% | +$7.86M |
| Intuitive Surgical, Inc.(ISRG) | 83,417 | 77,297 | -6,120 | $47.24M | $35.63M | 1.19% | -$11.61M |
| Inspire Medical Systems, Inc.(INSP) | 540,890 | 677,570 | +136,680 | $49.89M | $34.95M | 1.17% | -$14.94M |
| Penumbra, Inc.(PEN) | 110,152 | 105,352 | -4,800 | $34.25M | $34.59M | 1.15% | +$347.1K |
| TransMedics Group, Inc.(TMDX) | 315,341 | 329,391 | +14,050 | $38.36M | $32.74M | 1.09% | -$5.62M |
| Soleno Therapeutics Inc | 1,187,859 | 959,259 | -228,600 | $55.00M | $32.12M | 1.07% | -$22.88M |
| Dyne Therapeutics, Inc.(DYN) | 1,478,329 | 1,681,998 | +203,669 | $28.92M | $30.49M | 1.02% | +$1.58M |
| Maravai LifeSciences Holdings, Inc.CL A(MRVI) | 8,353,287 | 10,240,164 | +1,886,877 | $27.15M | $28.98M | 0.97% | +$1.83M |
| Illumina, Inc.(ILMN) | 269,673 | 229,215 | -40,458 | $35.37M | $28.25M | 0.94% | -$7.12M |
| Kymera Therapeutics, Inc.(KYMR) | 454,259 | 337,559 | -116,700 | $35.35M | $28.12M | 0.94% | -$7.23M |
| BioMarin Pharmaceutical Inc.(BMRN) | 601,520 | 497,020 | -104,500 | $35.75M | $28.08M | 0.94% | -$7.67M |
| Nurix Therapeutics, Inc.(NRIX) | 2,183,864 | 1,750,766 | -433,098 | $41.43M | $27.14M | 0.91% | -$14.29M |
| Rhythm Pharmaceuticals, Inc.(RYTM) | 0 | 310,628 | +310,628 | $0 | $27.02M | 0.90% | +$27.02M |
| Danaher Corporation(DHR) | 118,227 | 139,327 | +21,100 | $27.06M | $26.42M | 0.88% | -$648.1K |
| Establishment Labs Holdings Inc.(ESTA) | 0 | 463,600 | +463,600 | $0 | $26.32M | 0.88% | +$26.32M |
| Tectonic Therapeutic, Inc.(TECX) | 927,524 | 847,151 | -80,373 | $19.35M | $26.19M | 0.87% | +$6.84M |
| Natera, Inc.(NTRA) | 111,500 | 129,000 | +17,500 | $25.54M | $25.80M | 0.86% | +$255.2K |
| Corvus Pharmaceuticals, Inc.(CRVS) | 0 | 1,752,798 | +1,752,798 | $0 | $25.64M | 0.86% | +$25.64M |
| Fulcrum Therapeutics, Inc.(FULC) | 3,061,222 | 3,134,922 | +73,700 | $34.62M | $24.04M | 0.80% | -$10.58M |
| Zura Bio LimitedCL A(ZURA) | 3,180,389 | 3,988,989 | +808,600 | $16.67M | $23.73M | 0.79% | +$7.07M |
| Alphatec Holdings, Inc.(ATEC) | 0 | 2,172,725 | +2,172,725 | $0 | $23.64M | 0.79% | +$23.64M |
| Damora Therapeutics, Inc.(DMRA) | 0 | 894,846 | +894,846 | $0 | $23.18M | 0.77% | +$23.18M |
| Boston Scientific Corporation(BSX) | 0 | 346,467 | +346,467 | $0 | $21.74M | 0.73% | +$21.74M |
| Vera Therapeutics, Inc.CL A(VERA) | 784,742 | 523,824 | -260,918 | $39.74M | $21.07M | 0.70% | -$18.67M |
| BioAge Labs, Inc.(BIOA) | 0 | 1,200,587 | +1,200,587 | $0 | $21.00M | 0.70% | +$21.00M |
| CVS Health Corporation(CVS) | 564,200 | 290,700 | -273,500 | $44.77M | $20.88M | 0.70% | -$23.90M |
| Tarsus Pharmaceuticals, Inc.(TARS) | 0 | 265,715 | +265,715 | $0 | $18.64M | 0.62% | +$18.64M |
| Elevance Health, Inc.(ELV) | 0 | 62,080 | +62,080 | $0 | $18.17M | 0.61% | +$18.17M |
| OrthoPediatrics Corp.(KIDS) | 1,100,370 | 1,100,370 | 0 | $19.54M | $17.46M | 0.58% | -$2.08M |
| Engene Holdings Inc COM | 3,131,319 | 2,456,870 | -674,449 | $28.28M | $16.73M | 0.56% | -$11.54M |
| Nektar Therapeutics(NKTR) | 0 | 222,701 | +222,701 | $0 | $16.02M | 0.53% | +$16.02M |
| Acadia Healthcare Company, Inc.(ACHC) | 0 | 645,900 | +645,900 | $0 | $15.11M | 0.50% | +$15.11M |
| ORIC Pharmaceuticals, Inc.(ORIC) | 0 | 1,128,040 | +1,128,040 | $0 | $14.29M | 0.48% | +$14.29M |
| Aveanna Healthcare Holdings Inc.(AVAH) | 0 | 2,203,506 | +2,203,506 | $0 | $14.19M | 0.47% | +$14.19M |
| X4 Pharmaceuticals, Inc.(XFOR) | 3,368,904 | 3,272,954 | -95,950 | $13.48M | $13.52M | 0.45% | +$41.7K |
| Zenas BioPharma, Inc.NOTE 2 500 4 0(ZBIO) | 0 | 0 | 0 | $0 | $13.46M | 0.45% | +$13.46M |
| Kiniksa Pharmaceuticals International, plcCL A(KNSA) | 313,823 | 272,522 | -41,301 | $12.95M | $13.12M | 0.44% | +$176.7K |
| Evolus, Inc.(EOLS) | 3,105,209 | 3,105,209 | 0 | $20.65M | $12.76M | 0.43% | -$7.89M |
| TG Therapeutics, Inc.(TGTX) | 0 | 358,800 | +358,800 | $0 | $11.92M | 0.40% | +$11.92M |
| Surrozen, Inc.(SRZN) | 470,000 | 396,100 | -73,900 | $10.62M | $11.54M | 0.38% | +$916.4K |
| Centene Corporation(CNC) | 0 | 330,000 | +330,000 | $0 | $10.80M | 0.36% | +$10.80M |
| Climb Bio, Inc.(CLYM) | 0 | 1,529,675 | +1,529,675 | $0 | $10.48M | 0.35% | +$10.48M |
| Compass Therapeutics, Inc.(CMPX) | 2,786,778 | 1,965,106 | -821,672 | $14.96M | $10.40M | 0.35% | -$4.57M |
| Ionis Pharmaceuticals, Inc.(IONS) | 0 | 130,862 | +130,862 | $0 | $9.83M | 0.33% | +$9.83M |
| Helix Acquisition Corp. IIICL A(HLXC) | 0 | 900,000 | +900,000 | $0 | $9.27M | 0.31% | +$9.27M |
| Vor Biopharma Inc.(VOR) | 0 | 466,774 | +466,774 | $0 | $8.33M | 0.28% | +$8.33M |
| Revolution Medicines, Inc.(RVMD) | 0 | 84,900 | +84,900 | $0 | $8.26M | 0.28% | +$8.26M |
| GRAIL, Inc.(GRAL) | 142,755 | 142,755 | 0 | $12.22M | $7.38M | 0.25% | -$4.84M |
| Aclaris Therapeutics, Inc.(ACRS) | 0 | 1,699,116 | +1,699,116 | $0 | $6.37M | 0.21% | +$6.37M |
| Denali Therapeutics Inc.(DNLI) | 0 | 296,324 | +296,324 | $0 | $5.69M | 0.19% | +$5.69M |
| Repligen Corporation(RGEN) | 81,790 | 47,500 | -34,290 | $13.40M | $5.60M | 0.19% | -$7.81M |
| Harrow, Inc.(HROW) | 295,291 | 156,419 | -138,872 | $14.47M | $5.52M | 0.18% | -$8.95M |
| Revvity, Inc.(RVTY) | 0 | 48,400 | +48,400 | $0 | $4.24M | 0.14% | +$4.24M |
| Celcuity Inc.(CELC) | 0 | 29,198 | +29,198 | $0 | $3.33M | 0.11% | +$3.33M |
| Praxis Precision Medicines, Inc.(PRAX) | 0 | 9,976 | +9,976 | $0 | $3.21M | 0.11% | +$3.21M |
| Arrowhead Pharmaceuticals, Inc.NOTE 1 1(ARWR) | 0 | 0 | 0 | $0 | $2.33M | 0.08% | +$2.33M |
| Pulmonx Corporation(LUNG) | 752,541 | 752,541 | 0 | $1.66M | $970.8K | 0.03% | -$692.3K |
| Yarrow Bioscience Inc(YARW) | 0 | 916,077 | +916,077 | $0 | $547.4K | 0.02% | +$547.4K |
| Adaptive Biotechnologies Corporation(ADPT) | 311,991 | 0 | -311,991 | $5.07M | $0 | — | -$5.07M |
| Align Technology Inc | 381,004 | 0 | -381,004 | $59.49M | $0 | — | -$59.49M |
| Billiontoone IncCL A | 50,000 | 0 | -50,000 | $4.09M | $0 | — | -$4.09M |
| Biogen Inc.(BIIB) | 115,700 | 0 | -115,700 | $20.36M | $0 | — | -$20.36M |
| Castle Biosciences, Inc.(CSTL) | 177,183 | 0 | -177,183 | $6.89M | $0 | — | -$6.89M |
| ICON Public Limited CompanySHS(ICLR) | 73,370 | 0 | -73,370 | $13.37M | $0 | — | -$13.37M |
| iRhythm Holdings, Inc.NOTE 1 500 9 0(IRTC) | 0 | 0 | 0 | $72.80M | $0 | — | -$72.80M |
| Ironwood Pharmaceuticals, Inc.NOTE 1 500 6 1(IRWD) | 0 | 0 | 0 | $50.47M | $0 | — | -$50.47M |
| Karyopharm Therapeutics Inc.(KPTI) | 303,370 | 0 | -303,370 | $2.23M | $0 | — | -$2.23M |
| Legend Biotech CorporationADS(LEGN) | 1,298,142 | 0 | -1,298,142 | $28.22M | $0 | — | -$28.22M |
| Oruka Therapeutics, Inc.(ORKA) | 84,795 | 0 | -84,795 | $2.57M | $0 | — | -$2.57M |
| Rapt Therapeutics Inc | 929,694 | 0 | -929,694 | $31.49M | $0 | — | -$31.49M |