Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q2 2025 ▲▼ | Q3 2025 ▲▼ | Change ▲▼ | Q2 2025 ▲▼ | Q3 2025 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| Guardant Health, Inc.DEBT 1 250 2 1(GH) | 0 | 0 | 0 | $256.36M | $286.28M | 8.49% | +$29.92M |
| Caris Life Sciences, Inc.(CAI) | 7,316,142 | 7,316,142 | 0 | $195.49M | $221.31M | 6.57% | +$25.83M |
| NovoCure LimitedNOTE 11 0(NVCR) | 0 | 0 | 0 | $137.85M | $210.04M | 6.23% | +$72.19M |
| Xenon Pharmaceuticals Inc.(XENE) | 3,605,029 | 3,605,029 | 0 | $112.84M | $144.74M | 4.29% | +$31.90M |
| CG Oncology, Inc.(CGON) | 3,283,317 | 3,283,317 | 0 | $85.37M | $132.25M | 3.92% | +$46.89M |
| Neurocrine Biosciences, Inc.(NBIX) | 1,160,425 | 880,282 | -280,143 | $145.85M | $123.57M | 3.67% | -$22.28M |
| Repligen CorporationNOTE 1 000 12 1(RGEN) | 0 | 0 | 0 | $100.55M | $101.81M | 3.02% | +$1.26M |
| Krystal Biotech, Inc.(KRYS) | 727,811 | 520,401 | -207,410 | $100.04M | $91.87M | 2.73% | -$8.18M |
| Nuvalent Inc | 1,175,876 | 1,012,982 | -162,894 | $89.72M | $87.60M | 2.60% | -$2.12M |
| NeoGenomics, Inc.NOTE 0 250 1 1(NEO) | 0 | 0 | 0 | $87.06M | $86.83M | 2.58% | -$231.4K |
| Soleno Therapeutics Inc | 0 | 1,281,989 | +1,281,989 | $0 | $86.66M | 2.57% | +$86.66M |
| iRhythm Holdings, Inc.NOTE 1 500 9 0(IRTC) | 0 | 0 | 0 | $89.98M | $85.37M | 2.53% | -$4.61M |
| Edgewise Therapeutics, Inc.(EWTX) | 5,210,831 | 5,210,831 | 0 | $68.31M | $84.52M | 2.51% | +$16.21M |
| Ironwood Pharmaceuticals, Inc.NOTE 1 500 6 1(IRWD) | 0 | 0 | 0 | $78.37M | $72.90M | 2.16% | -$5.47M |
| Inspire Medical Systems, Inc.(INSP) | 522,410 | 883,747 | +361,337 | $67.79M | $65.57M | 1.95% | -$2.22M |
| Glaukos Corporation(GKOS) | 603,414 | 780,164 | +176,750 | $62.33M | $63.62M | 1.89% | +$1.30M |
| Danaher Corporation(DHR) | 309,339 | 309,339 | 0 | $61.11M | $61.33M | 1.82% | +$222.7K |
| Legend Biotech CorporationADS(LEGN) | 2,542,104 | 1,826,155 | -715,949 | $90.22M | $59.55M | 1.77% | -$30.67M |
| Intuitive Surgical, Inc.(ISRG) | 89,600 | 130,227 | +40,627 | $48.69M | $58.24M | 1.73% | +$9.55M |
| Apogee Therapeutics Inc | 1,478,512 | 1,438,745 | -39,767 | $64.21M | $57.16M | 1.70% | -$7.05M |
| argenx SEADR(ARGX) | 194,491 | 76,091 | -118,400 | $107.21M | $56.12M | 1.67% | -$51.09M |
| Thermo Fisher Scientific Inc.(TMO) | 135,233 | 113,933 | -21,300 | $54.83M | $55.26M | 1.64% | +$428.2K |
| Align Technology Inc | 496,730 | 409,691 | -87,039 | $94.05M | $51.30M | 1.52% | -$42.74M |
| Acadia Pharmaceuticals Inc | 0 | 2,378,655 | +2,378,655 | $0 | $50.76M | 1.51% | +$50.76M |
| Hinge Health, Inc.CL A(HNGE) | 0 | 910,476 | +910,476 | $0 | $44.69M | 1.33% | +$44.69M |
| Spyre Therapeutics, Inc.(SYRE) | 2,578,404 | 2,578,404 | 0 | $38.60M | $43.21M | 1.28% | +$4.62M |
| TransMedics Group, Inc.(TMDX) | 255,048 | 351,248 | +96,200 | $34.18M | $39.41M | 1.17% | +$5.23M |
| iRhythm Holdings, Inc.(IRTC) | 300,029 | 225,845 | -74,184 | $46.19M | $38.84M | 1.15% | -$7.35M |
| Penumbra, Inc.(PEN) | 129,628 | 141,528 | +11,900 | $33.27M | $35.85M | 1.06% | +$2.59M |
| Karyopharm Therapeutics IncNOTE 6 000 5 1 | 0 | 0 | 0 | $35.54M | $34.96M | 1.04% | -$581.8K |
| Dyne Therapeutics, Inc.(DYN) | 3,273,349 | 2,730,481 | -542,868 | $31.16M | $34.54M | 1.02% | +$3.38M |
| CVS Health Corporation(CVS) | 0 | 438,600 | +438,600 | $0 | $33.07M | 0.98% | +$33.07M |
| Dianthus Therapeutics, Inc.(DNTH) | 0 | 835,057 | +835,057 | $0 | $32.86M | 0.97% | +$32.86M |
| CareDx, Inc.(CDNA) | 0 | 2,182,781 | +2,182,781 | $0 | $31.74M | 0.94% | +$31.74M |
| BioMarin Pharmaceutical Inc.(BMRN) | 0 | 528,000 | +528,000 | $0 | $28.60M | 0.85% | +$28.60M |
| Globus Medical, Inc.CL A(GMED) | 247,200 | 498,000 | +250,800 | $14.59M | $28.52M | 0.85% | +$13.93M |
| Oruka Therapeutics, Inc.(ORKA) | 1,524,842 | 1,382,350 | -142,492 | $17.09M | $26.58M | 0.79% | +$9.49M |
| Repligen Corporation(RGEN) | 144,556 | 195,656 | +51,100 | $17.98M | $26.15M | 0.78% | +$8.17M |
| Kiniksa Pharmaceuticals International, plcCL A(KNSA) | 1,102,580 | 643,180 | -459,400 | $30.51M | $24.97M | 0.74% | -$5.53M |
| Tenet Healthcare Corporation(THC) | 0 | 121,700 | +121,700 | $0 | $24.71M | 0.73% | +$24.71M |
| Maravai LifeSciences Holdings, Inc.CL A(MRVI) | 8,353,287 | 8,353,287 | 0 | $20.13M | $23.97M | 0.71% | +$3.84M |
| Endeavour Silver Corp.(EXK) | 0 | 414,600 | +414,600 | $0 | $22.68M | 0.67% | +$22.68M |
| Akero Therapeutics Inc | 0 | 475,400 | +475,400 | $0 | $22.57M | 0.67% | +$22.57M |
| Alphatec Holdings, Inc.(ATEC) | 3,635,172 | 1,514,604 | -2,120,568 | $40.35M | $22.02M | 0.65% | -$18.33M |
| OrthoPediatrics Corp.(KIDS) | 1,107,770 | 1,107,770 | 0 | $23.79M | $20.53M | 0.61% | -$3.27M |
| Viking Therapeutics, Inc.(VKTX) | 1,437,555 | 759,455 | -678,100 | $38.10M | $19.96M | 0.59% | -$18.14M |
| Castle Biosciences, Inc.(CSTL) | 822,735 | 822,735 | 0 | $16.80M | $18.73M | 0.56% | +$1.93M |
| Bright Minds Biosciences Inc.(DRUG) | 0 | 303,685 | +303,685 | $0 | $18.42M | 0.55% | +$18.42M |
| Ultragenyx Pharmaceutical Inc.(RARE) | 0 | 588,700 | +588,700 | $0 | $17.71M | 0.53% | +$17.71M |
| Harrow, Inc.(HROW) | 872,246 | 342,391 | -529,855 | $26.64M | $16.50M | 0.49% | -$10.14M |
| Sarepta Therapeutics, Inc.(SRPT) | 0 | 832,100 | +832,100 | $0 | $16.03M | 0.48% | +$16.03M |
| Kymera Therapeutics, Inc.(KYMR) | 0 | 276,692 | +276,692 | $0 | $15.66M | 0.46% | +$15.66M |
| Engene Holdings Inc COM | 0 | 2,266,319 | +2,266,319 | $0 | $15.48M | 0.46% | +$15.48M |
| Day One Biopharmaceuticals I COM | 2,181,598 | 2,181,598 | 0 | $14.18M | $15.38M | 0.46% | +$1.20M |
| Celldex Therapeutics, Inc.(CLDX) | 0 | 591,689 | +591,689 | $0 | $15.31M | 0.45% | +$15.31M |
| Xencor, Inc.(XNCR) | 1,655,690 | 1,246,280 | -409,410 | $13.01M | $14.62M | 0.43% | +$1.61M |
| Avidity Biosciences Inc | 0 | 331,907 | +331,907 | $0 | $14.46M | 0.43% | +$14.46M |
| Encompass Health Corporation(EHC) | 0 | 113,335 | +113,335 | $0 | $14.40M | 0.43% | +$14.40M |
| Vera Therapeutics, Inc.CL A(VERA) | 0 | 472,739 | +472,739 | $0 | $13.74M | 0.41% | +$13.74M |
| NeoGenomics, Inc.(NEO) | 0 | 1,771,146 | +1,771,146 | $0 | $13.67M | 0.41% | +$13.67M |
| DexCom, Inc.NOTE 0 250 11 1(DXCM) | 0 | 0 | 0 | $18.22M | $13.41M | 0.40% | -$4.81M |
| Tectonic Therapeutic, Inc.(TECX) | 0 | 736,867 | +736,867 | $0 | $11.56M | 0.34% | +$11.56M |
| Replimune Group, Inc.(REPL) | 422,887 | 2,750,092 | +2,327,205 | $3.93M | $11.52M | 0.34% | +$7.59M |
| Adaptive Biotechnologies Corporation(ADPT) | 3,863,107 | 736,014 | -3,127,093 | $45.01M | $11.01M | 0.33% | -$33.99M |
| Zura Bio LimitedCL A(ZURA) | 2,472,806 | 2,472,806 | 0 | $2.60M | $10.71M | 0.32% | +$8.11M |
| Sionna Therapeutics, Inc.(SION) | 1,081,855 | 314,013 | -767,842 | $18.77M | $9.24M | 0.27% | -$9.54M |
| Amylyx Pharmaceuticals, Inc.(AMLX) | 0 | 612,841 | +612,841 | $0 | $8.33M | 0.25% | +$8.33M |
| Royalty Pharma plcCL A(RPRX) | 0 | 182,068 | +182,068 | $0 | $6.42M | 0.19% | +$6.42M |
| Immunocore Holdings plcNOTE 2 500 2 0(IMCR) | 0 | 0 | 0 | $23.27M | $6.19M | 0.18% | -$17.08M |
| Fulcrum Therapeutics, Inc.(FULC) | 0 | 219,488 | +219,488 | $0 | $2.02M | 0.06% | +$2.02M |
| Surrozen, Inc.(SRZN) | 140,000 | 140,000 | 0 | $1.25M | $1.80M | 0.05% | +$552.3K |
| Heartflow, Inc.(HTFL) | 0 | 50,000 | +50,000 | $0 | $1.68M | 0.05% | +$1.68M |
| Pulmonx Corporation(LUNG) | 752,541 | 752,541 | 0 | $1.95M | $1.22M | 0.04% | -$730.0K |
| Alphatec Holdings, Inc.NOTE 0 750 8 0(ATEC) | 0 | 0 | 0 | $5.77M | $0 | — | -$5.77M |
| Apellis Pharmaceuticals Inc COM | 1,121,034 | 0 | -1,121,034 | $19.41M | $0 | — | -$19.41M |
| Celcuity Inc.(CELC) | 884,306 | 0 | -884,306 | $11.81M | $0 | — | -$11.81M |
| Crescent Biopharma, Inc.(CBIO) | 261,504 | 0 | -261,504 | $4.22M | $0 | — | -$4.22M |
| Guardant Health, Inc.(GH) | 837,800 | 0 | -837,800 | $43.60M | $0 | — | -$43.60M |
| Madrigal Pharmaceuticals, Inc.(MDGL) | 60,781 | 0 | -60,781 | $18.39M | $0 | — | -$18.39M |
| UnitedHealth Group Incorporated(UNH) | 49,400 | 0 | -49,400 | $15.41M | $0 | — | -$15.41M |