Securities ▲▼ | Shares | Value ($K) | |||||
|---|---|---|---|---|---|---|---|
Q4 2024 ▲▼ | Q1 2025 ▲▼ | Change ▲▼ | Q4 2024 ▲▼ | Q1 2025 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| VERONA PHARMA PLC | 0 | 96,821 | +96,821 | 0 | 6,147 | 7.33% | +6,147 |
| PFIZER INC(PFE) | 0 | 196,164 | +196,164 | 0 | 4,971 | 5.93% | +4,971 |
| TRAVERE THERAPEUTICS INC(TVTX) | 0 | 237,487 | +237,487 | 0 | 4,256 | 5.08% | +4,256 |
| LEGEND BIOTECH CORP(LEGN) | 69,594 | 160,442 | +90,848 | 2,265 | 5,444 | 6.49% | +3,179 |
| SPRINGWORKS THERAPEUTICS INC | 0 | 54,216 | +54,216 | 0 | 2,393 | 2.85% | +2,393 |
| CAPRICOR THERAPEUTICS INC(CAPR) | 55,229 | 241,192 | +185,963 | 762 | 2,289 | 2.73% | +1,527 |
| UROGEN PHARMA LTD(URGN) | 301,206 | 423,632 | +122,426 | 3,208 | 4,685 | 5.59% | +1,478 |
| CRINETICS PHARMACEUTICALS IN(CRNX) | 0 | 43,613 | +43,613 | 0 | 1,463 | 1.74% | +1,463 |
| SOLENO THERAPEUTICS INC | 0 | 19,332 | +19,332 | 0 | 1,381 | 1.65% | +1,381 |
| MOONLAKE IMMUNOTHERAPEUTICS(MLTX) | 0 | 32,145 | +32,145 | 0 | 1,256 | 1.50% | +1,256 |
| SAVARA INC(SVRA) | 508,338 | 966,203 | +457,865 | 1,561 | 2,676 | 3.19% | +1,116 |
| TAYSHA GENE THERAPIES INC(TSHA) | 0 | 755,599 | +755,599 | 0 | 1,050 | 1.25% | +1,050 |
| VERASTEM INC(VSTM) | 209,889 | 336,363 | +126,474 | 1,085 | 2,028 | 2.42% | +943 |
| MADRIGAL PHARMACEUTICALS INC(MDGL) | 1,129 | 3,815 | +2,686 | 348 | 1,264 | 1.51% | +915 |
| TECTONIC THERAPEUTIC INC(TECX) | 0 | 50,746 | +50,746 | 0 | 899 | 1.07% | +899 |
| AVIDITY BIOSCIENCES INC | 0 | 22,271 | +22,271 | 0 | 657 | 0.78% | +657 |
| VAXCYTE INC(PCVX) | 0 | 11,264 | +11,264 | 0 | 425 | 0.51% | +425 |
| OCULAR THERAPEUTIX INC(OCUL) | 0 | 42,297 | +42,297 | 0 | 310 | 0.37% | +310 |
| SCHRODINGER INC(SDGR) | 0 | 14,114 | +14,114 | 0 | 279 | 0.33% | +279 |
| ZAI LAB LTD(ZLAB) | 403,630 | 294,947 | -108,683 | 10,571 | 10,659 | 12.71% | +88 |
| LAKESHORE BIOPHARMA CO LTD | 30,792 | 30,792 | 0 | 106 | 75 | 0.09% | -32 |
| ZENAS BIOPHARMA INC(ZBIO) | 111,605 | 111,605 | 0 | 914 | 882 | 1.05% | -32 |
| CLIMB BIO INC(CLYM) | 98,160 | 0 | -98,160 | 177 | 0 | — | -177 |
| 89BIO INC | 132,982 | 109,156 | -23,826 | 1,040 | 794 | 0.95% | -246 |
| CENTURY THERAPEUTICS INC(IPSC) | 462,963 | 462,963 | 0 | 468 | 220 | 0.26% | -247 |
| KYVERNA THERAPEUTICS INC(KYTX) | 182,177 | 191,287 | +9,110 | 681 | 369 | 0.44% | -312 |
| LEXEO THERAPEUTICS INC(LXEO) | 52,616 | 0 | -52,616 | 346 | 0 | — | -346 |
| AXSOME THERAPEUTICS INC(AXSM) | 4,268 | 0 | -4,268 | 361 | 0 | — | -361 |
| PROTARA THERAPEUTICS INC(TARA) | 360,000 | 360,000 | 0 | 1,901 | 1,534 | 1.83% | -367 |
| EYEPOINT PHARMACEUTICALS INC(EYPT) | 49,375 | 0 | -49,375 | 368 | 0 | — | -368 |
| SUMMIT THERAPEUTICS INC(SMMT) | 164,564 | 132,019 | -32,545 | 2,937 | 2,547 | 3.04% | -390 |
| ZURA BIO LTD(ZURA) | 186,943 | 0 | -186,943 | 467 | 0 | — | -467 |
| REZOLUTE INC(RZLT) | 123,184 | 0 | -123,184 | 604 | 0 | — | -604 |
| BRIDGEBIO PHARMA INC(BBIO) | 262,141 | 183,922 | -78,219 | 7,193 | 6,358 | 7.58% | -835 |
| BEIGENE LTD(ONC) | 6,365 | 0 | -6,365 | 1,176 | 0 | — | -1,176 |
| CABALETTA BIO INC(CABA) | 822,293 | 458,972 | -363,321 | 1,867 | 636 | 0.76% | -1,231 |
| INCYTE CORP(INCY) | 18,009 | 0 | -18,009 | 1,244 | 0 | — | -1,244 |
| KURA ONCOLOGY INC(KURA) | 157,959 | 0 | -157,959 | 1,376 | 0 | — | -1,376 |
| TANGO THERAPEUTICS INC(TNGX) | 474,955 | 0 | -474,955 | 1,468 | 0 | — | -1,468 |
| DYNE THERAPEUTICS INC(DYN) | 73,150 | 0 | -73,150 | 1,723 | 0 | — | -1,723 |
| FATE THERAPEUTICS INC(FATE) | 1,379,556 | 0 | -1,379,556 | 2,276 | 0 | — | -2,276 |
| COGENT BIOSCIENCES INC(COGT) | 910,865 | 774,721 | -136,144 | 7,105 | 4,641 | 5.54% | -2,464 |
| INSMED INC(INSM) | 35,966 | 0 | -35,966 | 2,483 | 0 | — | -2,483 |
| PROTAGONIST THERAPEUTICS INC | 68,892 | 0 | -68,892 | 2,659 | 0 | — | -2,659 |
| INSTIL BIO INC(TIL) | 148,017 | 0 | -148,017 | 2,826 | 0 | — | -2,826 |
| CYTOKINETICS INC(CYTK) | 129,389 | 72,992 | -56,397 | 6,086 | 2,934 | 3.50% | -3,153 |
| IDEAYA BIOSCIENCES INC(IDYA) | 227,102 | 0 | -227,102 | 5,837 | 0 | — | -5,837 |
| STRUCTURE THERAPEUTICS INC | 216,811 | 0 | -216,811 | 5,880 | 0 | — | -5,880 |
| TERNS PHARMACEUTICALS INC | 2,020,562 | 1,357,153 | -663,409 | 11,194 | 3,746 | 4.47% | -7,448 |
| ORIC PHARMACEUTICALS INC(ORIC) | 1,580,745 | 819,194 | -761,551 | 12,757 | 4,571 | 5.45% | -8,186 |
| NOVOCURE LTD(NVCR) | 286,970 | 0 | -286,970 | 8,552 | 0 | — | -8,552 |