Securities ▲▼ | Shares | Value ($K) | |||||
|---|---|---|---|---|---|---|---|
Q4 2025 ▲▼ | Q1 2026 ▲▼ | Change ▲▼ | Q4 2025 ▲▼ | Q1 2026 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| SUMMIT THERAPEUTICS INC(SMMT) | 0 | 892,873 | +892,873 | 0 | 16,929 | 12.09% | +16,929 |
| DEFINIUM THERAPEUTICS INC(DFTX) | 0 | 351,461 | +351,461 | 0 | 6,643 | 4.75% | +6,643 |
| VIR BIOTECHNOLOGY INC(VIR) | 0 | 730,548 | +730,548 | 0 | 6,546 | 4.68% | +6,546 |
| VAXCYTE INC(PCVX) | 0 | 110,454 | +110,454 | 0 | 6,418 | 4.59% | +6,418 |
| VERTEX PHARMACEUTICALS INC(VRTX) | 0 | 11,010 | +11,010 | 0 | 4,916 | 3.51% | +4,916 |
| GENMAB A/S(GMAB) | 29,162 | 196,709 | +167,547 | 898 | 5,278 | 3.77% | +4,380 |
| IQVIA HLDGS INC(IQV) | 0 | 25,668 | +25,668 | 0 | 4,377 | 3.13% | +4,377 |
| MAPLIGHT THERAPEUTICS INC(MPLT) | 0 | 192,139 | +192,139 | 0 | 3,906 | 2.79% | +3,906 |
| ARVINAS INC(ARVN) | 0 | 312,620 | +312,620 | 0 | 3,314 | 2.37% | +3,314 |
| CELLDEX THERAPEUTICS INC NEW(CLDX) | 88,308 | 180,048 | +91,740 | 2,398 | 5,711 | 4.08% | +3,313 |
| ORUKA THERAPEUTICS INC(ORKA) | 0 | 63,591 | +63,591 | 0 | 3,119 | 2.23% | +3,119 |
| ADLAI NORTYE LTD(ANL) | 0 | 414,852 | +414,852 | 0 | 2,871 | 2.05% | +2,871 |
| SAVARA INC(SVRA) | 995,353 | 1,585,977 | +590,624 | 6,002 | 8,659 | 6.19% | +2,657 |
| PFIZER INC(PFE) | 0 | 74,000 | +74,000 | 0 | 2,078 | 1.48% | +2,078 |
| ZAI LAB LTD(ZLAB) | 196,853 | 275,818 | +78,965 | 3,472 | 5,188 | 3.71% | +1,716 |
| TRAVERE THERAPEUTICS INC(TVTX) | 38,022 | 102,754 | +64,732 | 1,453 | 3,053 | 2.18% | +1,600 |
| IMMUNOVANT INC(IMVT) | 288,677 | 357,606 | +68,929 | 7,338 | 8,883 | 6.35% | +1,545 |
| ACLARIS THERAPEUTICS INC(ACRS) | 0 | 366,490 | +366,490 | 0 | 1,374 | 0.98% | +1,374 |
| CLIMB BIO INC(CLYM) | 0 | 199,209 | +199,209 | 0 | 1,365 | 0.97% | +1,365 |
| TREVI THERAPEUTICS INC(TRVI) | 148,292 | 251,566 | +103,274 | 1,857 | 3,001 | 2.14% | +1,145 |
| TONIX PHARMACEUTICALS HLDG C(TNXP) | 0 | 63,540 | +63,540 | 0 | 874 | 0.62% | +874 |
| CULLINAN THERAPEUTICS INC(CGEM) | 0 | 59,484 | +59,484 | 0 | 845 | 0.60% | +845 |
| PALATIN TECHNOLOGIES INC(PTN) | 33,971 | 35,969 | +1,998 | 522 | 627 | 0.45% | +104 |
| BIOMEA FUSION INC(BMEA) | 250,000 | 250,000 | 0 | 310 | 383 | 0.27% | +73 |
| ENTERA BIO LTD(ENTX) | 17,142 | 0 | -17,142 | 33 | 0 | — | -33 |
| CENTURY THERAPEUTICS INC(IPSC) | 462,963 | 119,308 | -343,655 | 461 | 270 | 0.19% | -191 |
| INVENTIVA SA(IVA) | 100,000 | 0 | -100,000 | 465 | 0 | — | -465 |
| ORIC PHARMACEUTICALS INC(ORIC) | 255,370 | 115,234 | -140,136 | 2,089 | 1,460 | 1.04% | -629 |
| ULTRAGENYX PHARMACEUTICAL IN(RARE) | 31,738 | 0 | -31,738 | 730 | 0 | — | -730 |
| FULCRUM THERAPEUTICS INC(FULC) | 72,060 | 0 | -72,060 | 815 | 0 | — | -815 |
| PALISADE BIO INC(PALI) | 367,103 | 0 | -367,103 | 863 | 0 | — | -863 |
| AARDVARK THERAPEUTICS INC | 69,496 | 0 | -69,496 | 912 | 0 | — | -912 |
| SPRUCE BIOSCIENCES INC | 12,137 | 0 | -12,137 | 1,057 | 0 | — | -1,057 |
| DIANTHUS THERAPEUTICS INC(DNTH) | 26,249 | 0 | -26,249 | 1,082 | 0 | — | -1,082 |
| REZOLUTE INC(RZLT) | 513,765 | 0 | -513,765 | 1,212 | 0 | — | -1,212 |
| PROTARA THERAPEUTICS INC(TARA) | 360,000 | 121,457 | -238,543 | 1,919 | 633 | 0.45% | -1,286 |
| VIRIDIAN THERAPEUTICS INC(VRDN) | 43,230 | 0 | -43,230 | 1,345 | 0 | — | -1,345 |
| UNITED THERAPEUTICS CORP DEL(UTHR) | 9,451 | 5,186 | -4,265 | 4,605 | 3,075 | 2.20% | -1,530 |
| TYRA BIOSCIENCES INC(TYRA) | 58,677 | 0 | -58,677 | 1,543 | 0 | — | -1,543 |
| SIONNA THERAPEUTICS INC(SION) | 180,593 | 141,024 | -39,569 | 7,430 | 5,654 | 4.04% | -1,776 |
| CABALETTA BIO INC(CABA) | 2,253,550 | 1,066,239 | -1,187,311 | 4,935 | 2,868 | 2.05% | -2,067 |
| ASSEMBLY BIOSCIENCES INC | 65,273 | 0 | -65,273 | 2,220 | 0 | — | -2,220 |
| PALVELLA THERAPEUTICS INC NE(PVLA) | 25,469 | 0 | -25,469 | 2,666 | 0 | — | -2,666 |
| BRIGHT MINDS BIOSCIENCES INC(DRUG) | 47,278 | 13,311 | -33,967 | 3,690 | 971 | 0.69% | -2,718 |
| CAPRICOR THERAPEUTICS INC(CAPR) | 96,334 | 0 | -96,334 | 2,780 | 0 | — | -2,780 |
| AVALO THERAPEUTICS INC(AVTX) | 153,313 | 0 | -153,313 | 2,784 | 0 | — | -2,784 |
| QUINCE THERAPEUTICS INC(QNCX) | 858,711 | 0 | -858,711 | 2,877 | 0 | — | -2,877 |
| ZENAS BIOPHARMA INC(ZBIO) | 83,353 | 0 | -83,353 | 3,027 | 0 | — | -3,027 |
| BELITE BIO INC(BLTE) | 24,703 | 0 | -24,703 | 3,951 | 0 | — | -3,951 |
| TAYSHA GENE THERAPIES INC(TSHA) | 980,768 | 258,269 | -722,499 | 5,394 | 1,154 | 0.82% | -4,240 |
| COGENT BIOSCIENCES INC(COGT) | 366,238 | 225,158 | -141,080 | 13,009 | 8,666 | 6.19% | -4,342 |
| REVOLUTION MEDICINES INC(RVMD) | 54,879 | 0 | -54,879 | 4,371 | 0 | — | -4,371 |
| AXSOME THERAPEUTICS INC.(AXSM) | 37,433 | 11,217 | -26,216 | 6,837 | 1,896 | 1.35% | -4,941 |
| AMICUS THERAPEUTICS INC COM | 352,896 | 0 | -352,896 | 5,025 | 0 | — | -5,025 |
| OCULAR THERAPEUTIX INC(OCUL) | 418,080 | 0 | -418,080 | 5,075 | 0 | — | -5,075 |
| MIND MEDICINE MINDMED INC | 425,202 | 0 | -425,202 | 5,693 | 0 | — | -5,693 |
| DYNAVAX TECHNOLOGIES CORP | 525,592 | 0 | -525,592 | 8,084 | 0 | — | -8,084 |
| UROGEN PHARMA LTD(URGN) | 718,354 | 387,371 | -330,983 | 16,824 | 6,965 | 4.98% | -9,859 |
| TERNS PHARMACEUTICALS INC | 443,777 | 0 | -443,777 | 17,929 | 0 | — | -17,929 |
| CIDARA THERAPEUTICS INC | 85,098 | 0 | -85,098 | 18,797 | 0 | — | -18,797 |