Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q4 2025 ▲▼ | Q1 2026 ▲▼ | Change ▲▼ | Q4 2025 ▲▼ | Q1 2026 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| Insmed Incorporated(INSM) | 682,212 | 628,712 | -53,500 | $118.73M | $102.81M | 23.18% | -$15.93M |
| ABIVAX Société AnonymeADS(ABVX) | 600,747 | 600,747 | 0 | $81.01M | $66.89M | 15.08% | -$14.12M |
| Eli Lilly and Company(LLY) | 50,500 | 38,220 | -12,280 | $54.27M | $35.15M | 7.93% | -$19.12M |
| Trevi Therapeutics, Inc.(TRVI) | 2,013,602 | 2,013,602 | 0 | $25.21M | $24.02M | 5.42% | -$1.19M |
| argenx SEADR(ARGX) | 64,699 | 29,739 | -34,960 | $54.41M | $21.72M | 4.90% | -$32.69M |
| AstraZeneca PLC(AZN) | 0 | 95,376 | +95,376 | $0 | $18.81M | 4.24% | +$18.81M |
| Newamsterdam Pharma Company ORDINARY SHARES | 503,936 | 503,936 | 0 | $17.68M | $16.13M | 3.64% | -$1.55M |
| Dianthus Therapeutics, Inc.(DNTH) | 205,090 | 162,990 | -42,100 | $8.45M | $13.68M | 3.08% | +$5.23M |
| Revolution Medicines, Inc.(RVMD) | 104,190 | 124,990 | +20,800 | $8.30M | $12.16M | 2.74% | +$3.86M |
| Ionis Pharmaceuticals, Inc.(IONS) | 144,376 | 144,376 | 0 | $11.42M | $10.84M | 2.44% | -$580.4K |
| EyePoint, Inc.(EYPT) | 767,098 | 767,098 | 0 | $14.01M | $9.89M | 2.23% | -$4.13M |
| Quest Diagnostics Incorporated(DGX) | 40,817 | 40,817 | 0 | $7.08M | $8.00M | 1.80% | +$916.3K |
| Alumis Inc | 0 | 325,046 | +325,046 | $0 | $7.16M | 1.61% | +$7.16M |
| Viking Therapeutics, Inc.(VKTX) | 719,365 | 180,731 | -538,634 | $25.31M | $5.88M | 1.33% | -$19.43M |
| Merck & Co., Inc.(MRK) | 0 | 46,700 | +46,700 | $0 | $5.62M | 1.27% | +$5.62M |
| Terns Pharmaceuticals Inc | 0 | 104,800 | +104,800 | $0 | $5.53M | 1.25% | +$5.53M |
| Johnson & Johnson(JNJ) | 0 | 22,600 | +22,600 | $0 | $5.52M | 1.25% | +$5.52M |
| Sionna Therapeutics, Inc.(SION) | 119,741 | 119,741 | 0 | $4.93M | $4.80M | 1.08% | -$125.7K |
| Scholar Rock Holding Corporation(SRRK) | 96,285 | 96,285 | 0 | $4.24M | $4.73M | 1.07% | +$492.0K |
| Rapport Therapeutics, Inc.(RAPP) | 138,508 | 138,508 | 0 | $4.20M | $4.33M | 0.98% | +$131.6K |
| Ascendis Pharma A/SADR(ASND) | 17,740 | 17,740 | 0 | $3.78M | $4.06M | 0.91% | +$274.8K |
| Belite Bio, IncADS(BLTE) | 17,989 | 24,989 | +7,000 | $2.88M | $3.98M | 0.90% | +$1.11M |
| Xenon Pharmaceuticals Inc.(XENE) | 40,000 | 65,000 | +25,000 | $1.79M | $3.78M | 0.85% | +$1.99M |
| Mineralys Therapeutics, Inc.(MLYS) | 137,800 | 137,800 | 0 | $5.00M | $3.73M | 0.84% | -$1.27M |
| Roivant Sciences Ltd.SHS(ROIV) | 129,800 | 129,800 | 0 | $2.82M | $3.60M | 0.81% | +$778.8K |
| Palisade Bio, Inc.(PALI) | 1,992,367 | 1,992,367 | 0 | $4.68M | $3.49M | 0.79% | -$1.20M |
| Biogen Inc.(BIIB) | 0 | 18,437 | +18,437 | $0 | $3.38M | 0.76% | +$3.38M |
| ProKidney Corp.CL A(PROK) | 1,838,411 | 1,806,939 | -31,472 | $4.12M | $3.23M | 0.73% | -$883.6K |
| AbbVie Inc.(ABBV) | 14,500 | 14,500 | 0 | $3.31M | $3.15M | 0.71% | -$159.5K |
| United Therapeutics Corporation(UTHR) | 5,000 | 5,000 | 0 | $2.44M | $2.96M | 0.67% | +$528.6K |
| Bright Minds Biosciences Inc.(DRUG) | 33,407 | 38,407 | +5,000 | $2.61M | $2.80M | 0.63% | +$195.5K |
| Protagonist Therapeutics Inc | 22,951 | 22,931 | -20 | $2.00M | $2.42M | 0.54% | +$412.4K |
| Soleno Therapeutics Inc | 533,698 | 68,490 | -465,208 | $24.71M | $2.29M | 0.52% | -$22.42M |
| BrightSpring Health Services, Inc.(BTSG) | 41,600 | 53,800 | +12,200 | $1.56M | $2.29M | 0.52% | +$734.5K |
| Travere Therapeutics, Inc.(TVTX) | 70,700 | 70,700 | 0 | $2.70M | $2.10M | 0.47% | -$601.0K |
| Edgewise Therapeutics, Inc.(EWTX) | 0 | 65,500 | +65,500 | $0 | $2.06M | 0.47% | +$2.06M |
| Celcuity Inc.(CELC) | 12,900 | 15,576 | +2,676 | $1.29M | $1.78M | 0.40% | +$491.2K |
| BridgeBio Pharma, Inc.(BBIO) | 20,400 | 20,400 | 0 | $1.56M | $1.51M | 0.34% | -$45.5K |
| Kiniksa Pharmaceuticals International, plcCL A(KNSA) | 29,200 | 29,200 | 0 | $1.20M | $1.41M | 0.32% | +$201.5K |
| Cytokinetics, Incorporated(CYTK) | 0 | 16,300 | +16,300 | $0 | $1.07M | 0.24% | +$1.07M |
| Enliven Therapeutics Inc | 0 | 20,900 | +20,900 | $0 | $819.3K | 0.18% | +$819.3K |
| Praxis Precision Medicines, Inc.(PRAX) | 2,500 | 2,500 | 0 | $736.9K | $805.5K | 0.18% | +$68.6K |
| Tenax Therapeutics, Inc.(TENX) | 42,080 | 42,080 | 0 | $513.0K | $672.9K | 0.15% | +$159.9K |
| Kodiak Sciences Inc.(KOD) | 17,019 | 17,019 | 0 | $475.9K | $648.8K | 0.15% | +$172.9K |
| Nuvalent Inc | 8,100 | 4,900 | -3,200 | $814.8K | $502.0K | 0.11% | -$312.8K |
| Apogee Therapeutics Inc | 0 | 5,886 | +5,886 | $0 | $495.4K | 0.11% | +$495.4K |
| Avalo Therapeutics, Inc.(AVTX) | 41,570 | 28,970 | -12,600 | $754.9K | $432.5K | 0.10% | -$322.4K |
| PepGen Inc.(PEPG) | 205,324 | 205,324 | 0 | $1.34M | $363.4K | 0.08% | -$973.2K |
| Alnylam Pharmaceuticals, Inc.(ALNY) | 17,400 | 0 | -17,400 | $6.92M | $0 | — | -$6.92M |
| Alto Neuroscience, Inc.(ANRO) | 29,192 | 0 | -29,192 | $519.6K | $0 | — | -$519.6K |
| Lyra Therapeutics Inc | 8,756 | 0 | -8,756 | $27.0K | $0 | — | -$27.0K |
| Ocular Therapeutix, Inc.(OCUL) | 141,061 | 0 | -141,061 | $1.71M | $0 | — | -$1.71M |
| Palvella Therapeutics, Inc.(PVLA) | 59,200 | 0 | -59,200 | $6.20M | $0 | — | -$6.20M |
| uniQure N.V.SHS(QURE) | 1,023,539 | 0 | -1,023,539 | $24.49M | $0 | — | -$24.49M |
| Avidity Biosciences Inc | 60,100 | 0 | -60,100 | $4.34M | $0 | — | -$4.34M |
| ProShares Ultra SilverULTRA GOLD(AGQ) | 442,119 | 0 | -442,119 | $24.55M | $0 | — | -$24.55M |
| Upstream Bio, Inc.(UPB) | 68,653 | 0 | -68,653 | $1.86M | $0 | — | -$1.86M |
| Ventyx Biosciences Inc | 695,982 | 0 | -695,982 | $6.28M | $0 | — | -$6.28M |
| Cidara Therapeutics Inc | 70,824 | 0 | -70,824 | $15.64M | $0 | — | -$15.64M |
| AstraZeneca PLCADR(AZN) | 190,752 | 0 | -190,752 | $17.54M | $0 | — | -$17.54M |