Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q3 2025 ▲▼ | Q4 2025 ▲▼ | Change ▲▼ | Q3 2025 ▲▼ | Q4 2025 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| Insmed Incorporated(INSM) | 732,212 | 682,212 | -50,000 | $105.45M | $118.73M | 19.08% | +$13.29M |
| ABIVAX Société AnonymeADS(ABVX) | 225,453 | 600,747 | +375,294 | $19.14M | $81.01M | 13.02% | +$61.87M |
| argenx SEADR(ARGX) | 78,311 | 64,699 | -13,612 | $57.76M | $54.41M | 8.74% | -$3.35M |
| Eli Lilly and Company(LLY) | 28,700 | 50,500 | +21,800 | $21.90M | $54.27M | 8.72% | +$32.37M |
| Viking Therapeutics, Inc.(VKTX) | 146,179 | 719,365 | +573,186 | $3.84M | $25.31M | 4.07% | +$21.47M |
| Trevi Therapeutics, Inc.(TRVI) | 1,999,702 | 2,013,602 | +13,900 | $18.30M | $25.21M | 4.05% | +$6.91M |
| Soleno Therapeutics Inc | 672,176 | 533,698 | -138,478 | $45.44M | $24.71M | 3.97% | -$20.73M |
| ProShares Ultra SilverULTRA GOLD(AGQ) | 537,372 | 442,119 | -95,253 | $24.75M | $24.55M | 3.94% | -$204.9K |
| uniQure N.V.SHS(QURE) | 658,839 | 1,023,539 | +364,700 | $38.46M | $24.49M | 3.94% | -$13.96M |
| Newamsterdam Pharma Company ORDINARY SHARES | 194,838 | 503,936 | +309,098 | $5.54M | $17.68M | 2.84% | +$12.14M |
| AstraZeneca PLCADR(AZN) | 190,752 | 190,752 | 0 | $14.63M | $17.54M | 2.82% | +$2.90M |
| Cidara Therapeutics Inc | 0 | 70,824 | +70,824 | $0 | $15.64M | 2.51% | +$15.64M |
| EyePoint, Inc.(EYPT) | 628,367 | 767,098 | +138,731 | $8.95M | $14.01M | 2.25% | +$5.07M |
| Ionis Pharmaceuticals, Inc.(IONS) | 60,176 | 144,376 | +84,200 | $3.94M | $11.42M | 1.84% | +$7.48M |
| Dianthus Therapeutics, Inc.(DNTH) | 108,723 | 205,090 | +96,367 | $4.28M | $8.45M | 1.36% | +$4.17M |
| Revolution Medicines, Inc.(RVMD) | 104,190 | 104,190 | 0 | $4.87M | $8.30M | 1.33% | +$3.43M |
| Quest Diagnostics Incorporated(DGX) | 81,717 | 40,817 | -40,900 | $15.57M | $7.08M | 1.14% | -$8.49M |
| Alnylam Pharmaceuticals, Inc.(ALNY) | 34,570 | 17,400 | -17,170 | $15.76M | $6.92M | 1.11% | -$8.84M |
| Ventyx Biosciences Inc | 0 | 695,982 | +695,982 | $0 | $6.28M | 1.01% | +$6.28M |
| Palvella Therapeutics, Inc.(PVLA) | 0 | 59,200 | +59,200 | $0 | $6.20M | 1.00% | +$6.20M |
| Mineralys Therapeutics, Inc.(MLYS) | 56,600 | 137,800 | +81,200 | $2.15M | $5.00M | 0.80% | +$2.85M |
| Sionna Therapeutics, Inc.(SION) | 0 | 119,741 | +119,741 | $0 | $4.93M | 0.79% | +$4.93M |
| Palisade Bio, Inc.(PALI) | 0 | 1,992,367 | +1,992,367 | $0 | $4.68M | 0.75% | +$4.68M |
| Avidity Biosciences Inc | 110,100 | 60,100 | -50,000 | $4.80M | $4.34M | 0.70% | -$462.0K |
| Scholar Rock Holding Corporation(SRRK) | 96,285 | 96,285 | 0 | $3.59M | $4.24M | 0.68% | +$655.7K |
| Rapport Therapeutics, Inc.(RAPP) | 64,608 | 138,508 | +73,900 | $1.92M | $4.20M | 0.68% | +$2.28M |
| ProKidney Corp.CL A(PROK) | 0 | 1,838,411 | +1,838,411 | $0 | $4.12M | 0.66% | +$4.12M |
| Ascendis Pharma A/SADR(ASND) | 12,240 | 17,740 | +5,500 | $2.43M | $3.78M | 0.61% | +$1.35M |
| AbbVie Inc.(ABBV) | 14,500 | 14,500 | 0 | $3.36M | $3.31M | 0.53% | -$44.2K |
| Belite Bio, IncADS(BLTE) | 0 | 17,989 | +17,989 | $0 | $2.88M | 0.46% | +$2.88M |
| Roivant Sciences Ltd.SHS(ROIV) | 0 | 129,800 | +129,800 | $0 | $2.82M | 0.45% | +$2.82M |
| Travere Therapeutics, Inc.(TVTX) | 30,900 | 70,700 | +39,800 | $738.5K | $2.70M | 0.43% | +$1.96M |
| Bright Minds Biosciences Inc.(DRUG) | 0 | 33,407 | +33,407 | $0 | $2.61M | 0.42% | +$2.61M |
| United Therapeutics Corporation(UTHR) | 5,000 | 5,000 | 0 | $2.10M | $2.44M | 0.39% | +$340.2K |
| Protagonist Therapeutics Inc | 22,951 | 22,951 | 0 | $1.52M | $2.00M | 0.32% | +$479.9K |
| Upstream Bio, Inc.(UPB) | 0 | 68,653 | +68,653 | $0 | $1.86M | 0.30% | +$1.86M |
| Xenon Pharmaceuticals Inc.(XENE) | 40,000 | 40,000 | 0 | $1.61M | $1.79M | 0.29% | +$186.8K |
| Ocular Therapeutix, Inc.(OCUL) | 141,061 | 141,061 | 0 | $1.65M | $1.71M | 0.28% | +$63.5K |
| BridgeBio Pharma, Inc.(BBIO) | 20,400 | 20,400 | 0 | $1.06M | $1.56M | 0.25% | +$500.8K |
| BrightSpring Health Services, Inc.(BTSG) | 41,600 | 41,600 | 0 | $1.23M | $1.56M | 0.25% | +$328.2K |
| PepGen Inc.(PEPG) | 0 | 205,324 | +205,324 | $0 | $1.34M | 0.21% | +$1.34M |
| Celcuity Inc.(CELC) | 0 | 12,900 | +12,900 | $0 | $1.29M | 0.21% | +$1.29M |
| Kiniksa Pharmaceuticals International, plcCL A(KNSA) | 29,200 | 29,200 | 0 | $1.13M | $1.20M | 0.19% | +$70.7K |
| Nuvalent Inc | 0 | 8,100 | +8,100 | $0 | $814.8K | 0.13% | +$814.8K |
| Avalo Therapeutics, Inc.(AVTX) | 0 | 41,570 | +41,570 | $0 | $754.9K | 0.12% | +$754.9K |
| Praxis Precision Medicines, Inc.(PRAX) | 0 | 2,500 | +2,500 | $0 | $736.9K | 0.12% | +$736.9K |
| Alto Neuroscience, Inc.(ANRO) | 0 | 29,192 | +29,192 | $0 | $519.6K | 0.08% | +$519.6K |
| Tenax Therapeutics, Inc.(TENX) | 0 | 42,080 | +42,080 | $0 | $513.0K | 0.08% | +$513.0K |
| Kodiak Sciences Inc.(KOD) | 0 | 17,019 | +17,019 | $0 | $475.9K | 0.08% | +$475.9K |
| Lyra Therapeutics Inc | 0 | 8,756 | +8,756 | $0 | $27.0K | 0.00% | +$27.0K |
| Alector Inc | 71,029 | 0 | -71,029 | $210.2K | $0 | — | -$210.2K |
| Atyr Pharma Inc | 372,276 | 0 | -372,276 | $268.6K | $0 | — | -$268.6K |
| Biohaven Ltd.(BHVN) | 80,000 | 0 | -80,000 | $1.20M | $0 | — | -$1.20M |
| Boston Scientific Corporation(BSX) | 183,200 | 0 | -183,200 | $17.89M | $0 | — | -$17.89M |
| Centessa Pharmaceuticals PlcADS | 133,291 | 0 | -133,291 | $3.23M | $0 | — | -$3.23M |
| Iren Limited ORDINARY SHARES | 33,200 | 0 | -33,200 | $1.56M | $0 | — | -$1.56M |
| Kalvista Pharmaceuticals Inc | 41,555 | 0 | -41,555 | $506.1K | $0 | — | -$506.1K |
| Mereo BioPharma Group plcADS(MREO) | 475,361 | 0 | -475,361 | $979.2K | $0 | — | -$979.2K |
| Moderna, Inc.(MRNA) | 23,800 | 0 | -23,800 | $614.8K | $0 | — | -$614.8K |
| Merus N V | 296,750 | 0 | -296,750 | $27.94M | $0 | — | -$27.94M |
| Nektar Therapeutics(NKTR) | 57,999 | 0 | -57,999 | $3.30M | $0 | — | -$3.30M |
| Ultragenyx Pharmaceutical Inc.(RARE) | 64,502 | 0 | -64,502 | $1.94M | $0 | — | -$1.94M |
| Regeneron Pharmaceuticals, Inc.(REGN) | 10,671 | 0 | -10,671 | $6.00M | $0 | — | -$6.00M |
| Sarepta Therapeutics, Inc.(SRPT) | 44,900 | 0 | -44,900 | $865.2K | $0 | — | -$865.2K |
| TG Therapeutics, Inc.(TGTX) | 54,515 | 0 | -54,515 | $1.97M | $0 | — | -$1.97M |
| Verona Pharma PlcADS | 379,004 | 0 | -379,004 | $40.44M | $0 | — | -$40.44M |
| Vertex Pharmaceuticals Incorporated(VRTX) | 55,100 | 0 | -55,100 | $21.58M | $0 | — | -$21.58M |