Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q4 2025 ▲▼ | Q1 2026 ▲▼ | Change ▲▼ | Q4 2025 ▲▼ | Q1 2026 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| ABIVAX Société AnonymeADS(ABVX) | 1,317,329 | 1,394,019 | +76,690 | $177.65M | $155.22M | 9.33% | -$22.42M |
| Protagonist Therapeutics Inc | 1,049,168 | 994,119 | -55,049 | $91.63M | $104.78M | 6.30% | +$13.15M |
| Roivant Sciences Ltd.SHS(ROIV) | 3,428,962 | 3,285,906 | -143,056 | $74.41M | $91.02M | 5.47% | +$16.61M |
| Immunovant, Inc.(IMVT) | 2,480,968 | 2,679,010 | +198,042 | $63.07M | $66.55M | 4.00% | +$3.48M |
| State Street SPDR S&P 500 ETF TrustTR UNIT(SPY) | 54,684 | 75,940 | +21,256 | $37.29M | $49.39M | 2.97% | +$12.10M |
| Terns Pharmaceuticals Inc | 541,615 | 914,699 | +373,084 | $21.88M | $48.22M | 2.90% | +$26.34M |
| Cytokinetics, Incorporated(CYTK) | 540,166 | 632,556 | +92,390 | $34.32M | $41.69M | 2.51% | +$7.37M |
| Crinetics Pharmaceuticals In | 309,368 | 1,139,331 | +829,963 | $14.40M | $41.38M | 2.49% | +$26.98M |
| Ea Series TrustALPHA ARCH 1 3 ALPHA ARCH 1-3 | 337,125 | 337,125 | 0 | $38.80M | $39.20M | 2.36% | +$401.2K |
| Denali Therapeutics Inc.(DNLI) | 52,116 | 1,871,455 | +1,819,339 | $860.4K | $35.93M | 2.16% | +$35.07M |
| Beam Therapeutics Inc.(BEAM) | 0 | 1,446,375 | +1,446,375 | $0 | $34.47M | 2.07% | +$34.47M |
| Zai Lab LimitedADR(ZLAB) | 1,246,520 | 1,425,367 | +178,847 | $21.99M | $26.81M | 1.61% | +$4.82M |
| Septerna, Inc.(SEPN) | 1,157,611 | 1,089,818 | -67,793 | $32.27M | $26.19M | 1.57% | -$6.09M |
| Vir Biotechnology, Inc.(VIR) | 0 | 2,744,714 | +2,744,714 | $0 | $24.59M | 1.48% | +$24.59M |
| DBV Technologies S.A.ADS(DBVT) | 0 | 1,012,866 | +1,012,866 | $0 | $21.16M | 1.27% | +$21.16M |
| Anteris Technologies Global Corp.(AVR) | 1,238,777 | 3,789,132 | +2,550,355 | $6.18M | $21.03M | 1.26% | +$14.85M |
| Inspire Medical Systems, Inc.(INSP) | 15,000 | 405,197 | +390,197 | $1.38M | $20.90M | 1.26% | +$19.52M |
| Scholar Rock Holding Corporation(SRRK) | 69,589 | 407,273 | +337,684 | $3.07M | $20.02M | 1.20% | +$16.96M |
| Rhythm Pharmaceuticals, Inc.(RYTM) | 51,349 | 211,450 | +160,101 | $5.50M | $18.39M | 1.11% | +$12.89M |
| Spyre Therapeutics, Inc.(SYRE) | 34,051 | 338,323 | +304,272 | $1.12M | $17.07M | 1.03% | +$15.95M |
| CytomX Therapeutics, Inc.(CTMX) | 4,182,769 | 3,410,190 | -772,579 | $17.82M | $16.03M | 0.96% | -$1.79M |
| Prothena Corp PlcSHS SHS | 1,457,764 | 1,581,443 | +123,679 | $13.92M | $15.37M | 0.92% | +$1.45M |
| SanofiADR(SNY) | 63,474 | 316,939 | +253,465 | $3.08M | $15.27M | 0.92% | +$12.19M |
| Vaxcyte, Inc.(PCVX) | 315,642 | 259,137 | -56,505 | $14.56M | $15.06M | 0.90% | +$494.7K |
| Monopar Therapeutics Inc.(MNPR) | 233,908 | 264,278 | +30,370 | $15.27M | $14.48M | 0.87% | -$794.4K |
| Arbutus Biopharma Corporation(ABUS) | 5,415,109 | 3,133,175 | -2,281,934 | $26.05M | $14.10M | 0.85% | -$11.95M |
| Amylyx Pharmaceuticals, Inc.(AMLX) | 890,356 | 1,000,604 | +110,248 | $10.76M | $13.91M | 0.84% | +$3.15M |
| Celldex Therapeutics, Inc.(CLDX) | 646,767 | 427,816 | -218,951 | $17.57M | $13.57M | 0.82% | -$4.00M |
| Taysha Gene Therapies, Inc.(TSHA) | 2,495,809 | 2,979,429 | +483,620 | $13.73M | $13.32M | 0.80% | -$408.9K |
| Xenon Pharmaceuticals Inc.(XENE) | 203,969 | 228,899 | +24,930 | $9.14M | $13.31M | 0.80% | +$4.17M |
| Sutro Biopharma, Inc.(STRO) | 67,077 | 524,441 | +457,364 | $776.1K | $13.06M | 0.79% | +$12.29M |
| Revolution Medicines, Inc.(RVMD) | 145,079 | 133,893 | -11,186 | $11.56M | $13.02M | 0.78% | +$1.47M |
| Enliven Therapeutics Inc | 30,000 | 329,540 | +299,540 | $462.0K | $12.92M | 0.78% | +$12.46M |
| CG Oncology, Inc.(CGON) | 258,139 | 185,699 | -72,440 | $10.72M | $12.57M | 0.76% | +$1.85M |
| Spdr Series TrustSTATE STREET SPD ST STR BLO 1 ETF | 135,585 | 135,585 | 0 | $12.39M | $12.43M | 0.75% | +$35.3K |
| Establishment Labs Holdings Inc.(ESTA) | 171,422 | 213,473 | +42,051 | $12.49M | $12.12M | 0.73% | -$372.2K |
| Replimune Group, Inc.(REPL) | 1,241,322 | 1,582,987 | +341,665 | $12.07M | $12.11M | 0.73% | +$44.2K |
| Inventiva S.A.ADS(IVA) | 2,709,846 | 2,174,398 | -535,448 | $12.60M | $12.07M | 0.73% | -$532.9K |
| Ionis Pharmaceuticals, Inc.(IONS) | 147,130 | 160,338 | +13,208 | $11.64M | $12.04M | 0.72% | +$400.3K |
| Nektar Therapeutics(NKTR) | 72,031 | 161,252 | +89,221 | $3.05M | $11.60M | 0.70% | +$8.56M |
| Inhibikase Therapeutics, Inc.(IKT) | 8,063,949 | 6,606,572 | -1,457,377 | $16.53M | $11.10M | 0.67% | -$5.43M |
| ARS Pharmaceuticals, Inc.(SPRY) | 369,569 | 1,361,536 | +991,967 | $4.31M | $10.93M | 0.66% | +$6.63M |
| Helix Acquisition Corp. IIICL A(HLXC) | 0 | 1,000,000 | +1,000,000 | $0 | $10.30M | 0.62% | +$10.30M |
| Ovid Therapeutics Inc.(OVID) | 4,285,000 | 4,544,113 | +259,113 | $6.98M | $10.09M | 0.61% | +$3.10M |
| OnKure Therapeutics, Inc.CL A(OKUR) | 1,014,158 | 2,434,941 | +1,420,783 | $2.94M | $10.08M | 0.61% | +$7.14M |
| Regeneron Pharmaceuticals, Inc.(REGN) | 12,051 | 12,154 | +103 | $9.30M | $9.39M | 0.56% | +$88.9K |
| MoonLake ImmunotherapeuticsCL A(MLTX) | 0 | 457,137 | +457,137 | $0 | $8.52M | 0.51% | +$8.52M |
| Lexeo Therapeutics, Inc.(LXEO) | 1,393,161 | 1,467,350 | +74,189 | $13.83M | $8.42M | 0.51% | -$5.41M |
| Opus Genetics, Inc.(IRD) | 40,000 | 1,849,004 | +1,809,004 | $80.4K | $8.41M | 0.51% | +$8.33M |
| Teva Pharmaceutical Industries LimitedADS(TEVA) | 235,971 | 268,391 | +32,420 | $7.36M | $8.08M | 0.49% | +$719.3K |
| Savara Inc.(SVRA) | 1,405,452 | 1,464,535 | +59,083 | $8.47M | $8.00M | 0.48% | -$478.5K |
| MapLight Therapeutics, Inc.(MPLT) | 0 | 374,909 | +374,909 | $0 | $7.62M | 0.46% | +$7.62M |
| LeonaBio, Inc.(LONA) | 393,701 | 727,481 | +333,780 | $2.89M | $7.48M | 0.45% | +$4.59M |
| Equillium, Inc.(EQ) | 5,608,078 | 3,726,659 | -1,881,419 | $8.69M | $7.45M | 0.45% | -$1.24M |
| Viking Therapeutics, Inc.(VKTX) | 26,494 | 227,717 | +201,223 | $932.1K | $7.41M | 0.45% | +$6.48M |
| Damora Therapeutics, Inc.(DMRA) | 0 | 279,000 | +279,000 | $0 | $7.23M | 0.43% | +$7.23M |
| UroGen Pharma Ltd.(URGN) | 125,375 | 395,459 | +270,084 | $2.94M | $7.11M | 0.43% | +$4.17M |
| BridgeBio Pharma, Inc.(BBIO) | 213,414 | 94,292 | -119,122 | $16.32M | $7.00M | 0.42% | -$9.32M |
| Prime Medicine, Inc.(PRME) | 0 | 1,973,282 | +1,973,282 | $0 | $6.87M | 0.41% | +$6.87M |
| Vertex Pharmaceuticals Incorporated(VRTX) | 13,716 | 15,075 | +1,359 | $6.22M | $6.73M | 0.40% | +$513.3K |
| Korro Bio, Inc.(KRRO) | 0 | 540,054 | +540,054 | $0 | $6.11M | 0.37% | +$6.11M |
| Viridian Therapeutics, Inc.(VRDN) | 77,198 | 304,422 | +227,224 | $2.40M | $5.95M | 0.36% | +$3.55M |
| Danaher Corporation(DHR) | 25,600 | 30,932 | +5,332 | $5.86M | $5.86M | 0.35% | +$4.4K |
| Insmed Incorporated(INSM) | 0 | 35,392 | +35,392 | $0 | $5.79M | 0.35% | +$5.79M |
| Ascendis Pharma A/SADR(ASND) | 25,314 | 25,014 | -300 | $5.40M | $5.72M | 0.34% | +$323.5K |
| Brighthouse Financial, Inc.(BHF) | 95,523 | 95,523 | 0 | $6.19M | $5.72M | 0.34% | -$469.0K |
| Sarepta Therapeutics, Inc.(SRPT) | 28,866 | 262,058 | +233,192 | $621.2K | $5.70M | 0.34% | +$5.08M |
| Oaktree Acquisition Corp IiiUNIT 10 04 2029 UNIT 10/04/2029 | 516,482 | 516,482 | 0 | $5.49M | $5.50M | 0.33% | +$15.5K |
| Perceptive Cap Solutions CorCL A CL A ORD SHS | 456,720 | 499,581 | +42,861 | $5.95M | $5.48M | 0.33% | -$470.7K |
| Krystal Biotech, Inc.(KRYS) | 20,014 | 20,014 | 0 | $4.93M | $5.17M | 0.31% | +$235.8K |
| Acumen Pharmaceuticals, Inc.(ABOS) | 891,183 | 2,156,334 | +1,265,151 | $1.88M | $5.09M | 0.31% | +$3.21M |
| Invivyd, Inc.(IVVD) | 3,899,397 | 3,822,427 | -76,970 | $9.63M | $4.97M | 0.30% | -$4.66M |
| BridgeBio Pharma, Inc.NOTE 2 250 2 0(BBIO) | 0 | 0 | 0 | $0 | $4.94M | 0.30% | +$4.94M |
| BHAV Acquisition CorpUNIT 03 18 2031(BHAV) | 0 | 495,000 | +495,000 | $0 | $4.93M | 0.30% | +$4.93M |
| Protara Therapeutics, Inc.(TARA) | 1,136,799 | 940,512 | -196,287 | $6.06M | $4.90M | 0.29% | -$1.16M |
| BridgeBio Pharma, Inc.NOTE 1 750 3 0(BBIO) | 0 | 0 | 0 | $0 | $4.85M | 0.29% | +$4.85M |
| Agios Pharmaceuticals, Inc.(AGIO) | 188,000 | 140,672 | -47,328 | $5.12M | $4.76M | 0.29% | -$358.4K |
| Eli Lilly and Company(LLY) | 0 | 5,060 | +5,060 | $0 | $4.65M | 0.28% | +$4.65M |
| Dianthus Therapeutics, Inc.(DNTH) | 0 | 55,000 | +55,000 | $0 | $4.62M | 0.28% | +$4.62M |
| Arrowhead Pharmaceuticals, Inc.(ARWR) | 58,200 | 70,300 | +12,100 | $3.86M | $4.41M | 0.26% | +$543.9K |
| Belite Bio, IncADS(BLTE) | 39,839 | 26,880 | -12,959 | $6.37M | $4.29M | 0.26% | -$2.09M |
| Evommune, Inc.(EVMN) | 184,062 | 184,062 | 0 | $3.15M | $4.23M | 0.25% | +$1.08M |
| Mineralys Therapeutics, Inc.(MLYS) | 136,231 | 154,686 | +18,455 | $4.94M | $4.19M | 0.25% | -$753.4K |
| Janux Therapeutics, Inc.(JANX) | 245,452 | 298,546 | +53,094 | $3.39M | $4.15M | 0.25% | +$762.6K |
| Climb Bio, Inc.(CLYM) | 1,432,475 | 597,662 | -834,813 | $5.73M | $4.09M | 0.25% | -$1.64M |
| Palisade Bio, Inc.(PALI) | 2,004,845 | 2,264,845 | +260,000 | $4.71M | $3.96M | 0.24% | -$747.9K |
| American Exceptionalism AcquCL A ORD CL A | 357,539 | 357,539 | 0 | $4.07M | $3.87M | 0.23% | -$200.2K |
| Spruce Biosciences Inc | 58,000 | 58,600 | +600 | $5.05M | $3.83M | 0.23% | -$1.22M |
| Newamsterdam Pharma Company ORDINARY SHARES | 118,623 | 118,623 | 0 | $4.16M | $3.80M | 0.23% | -$364.2K |
| Zura Bio LimitedCL A(ZURA) | 562,065 | 630,403 | +68,338 | $2.95M | $3.75M | 0.23% | +$805.7K |
| Arcellx Inc COMMON STOCK | 31,484 | 32,084 | +600 | $2.05M | $3.68M | 0.22% | +$1.63M |
| Contineum Therapeutics, Inc.CL A(CTNM) | 278,961 | 276,661 | -2,300 | $3.19M | $3.61M | 0.22% | +$424.7K |
| BridgeBio Pharma, Inc.NOTE 2 500 3 1(BBIO) | 0 | 0 | 0 | $0 | $3.56M | 0.21% | +$3.56M |
| Monte Rosa Therapeutics, Inc.(GLUE) | 215,752 | 215,752 | 0 | $3.38M | $3.55M | 0.21% | +$166.1K |
| BeOne Medicines AGADS(ONC) | 0 | 11,701 | +11,701 | $0 | $3.47M | 0.21% | +$3.47M |
| Tenax Therapeutics, Inc.(TENX) | 63,673 | 213,462 | +149,789 | $776.2K | $3.41M | 0.21% | +$2.64M |
| ArriVent BioPharma, Inc.(AVBP) | 0 | 141,814 | +141,814 | $0 | $3.27M | 0.20% | +$3.27M |
| Pliant Therapeutics, Inc.(PLRX) | 73,819 | 2,585,126 | +2,511,307 | $90.1K | $3.26M | 0.20% | +$3.17M |
| Ataibeckley Inc | 0 | 913,242 | +913,242 | $0 | $3.23M | 0.19% | +$3.23M |
| Relmada Therapeutics, Inc.(RLMD) | 30,866 | 451,918 | +421,052 | $149.1K | $3.15M | 0.19% | +$3.00M |