Securities ▲▼ | Shares | Value ($K) | |||||
|---|---|---|---|---|---|---|---|
Q1 2024 ▲▼ | Q2 2024 ▲▼ | Change ▲▼ | Q1 2024 ▲▼ | Q2 2024 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| PROTAGONIST THERAPEUTICS INC | 785,655 | 1,603,932 | +818,277 | 22,729 | 55,576 | 11.19% | +32,847 |
| CYTOKINETICS INC(CYTK) | 319,510 | 853,862 | +534,352 | 22,401 | 46,262 | 9.32% | +23,861 |
| BRIDGEBIO PHARMA INC(BBIO) | 549,804 | 1,264,570 | +714,766 | 17,000 | 32,032 | 6.45% | +15,032 |
| ROIVANT SCIENCES LTD(ROIV) | 2,791,870 | 4,150,009 | +1,358,139 | 29,426 | 43,866 | 8.83% | +14,439 |
| IMMUNOVANT INC(IMVT) | 60,763 | 476,543 | +415,780 | 1,963 | 12,581 | 2.53% | +10,617 |
| MERCK & CO INC(MRK) | 300 | 75,750 | +75,450 | 40 | 9,378 | 1.89% | +9,338 |
| ROYALTY PHARMA PLC(RPRX) | 721,301 | 1,181,332 | +460,031 | 21,906 | 31,152 | 6.27% | +9,246 |
| REZOLUTE INC(RZLT) | 0 | 2,063,962 | +2,063,962 | 0 | 8,875 | 1.79% | +8,875 |
| PERCEPTIVE CAP SOLUTIONS COR CL A ORD SHS | 0 | 750,000 | +750,000 | 0 | 7,545 | 1.52% | +7,545 |
| TECTONIC THERAPEUTIC INC(TECX) | 0 | 356,878 | +356,878 | 0 | 5,878 | 1.18% | +5,878 |
| SOLID BIOSCIENCES INC | 203,204 | 1,420,422 | +1,217,218 | 2,707 | 8,054 | 1.62% | +5,347 |
| ARBUTUS BIOPHARMA CORP(ABUS) | 2,074,183 | 3,289,260 | +1,215,077 | 5,351 | 10,164 | 2.05% | +4,812 |
| EDGEWISE THERAPEUTICS INC(EWTX) | 180,911 | 436,608 | +255,697 | 3,300 | 7,863 | 1.58% | +4,563 |
| EA SERIES TRUST ALPHA ARCH 1-3 | 318,120 | 351,482 | +33,362 | 33,867 | 37,895 | 7.63% | +4,028 |
| UNIQURE NV(QURE) | 292,850 | 1,222,676 | +929,826 | 1,523 | 5,478 | 1.10% | +3,955 |
| ANAPTYSBIO INC | 1,000 | 155,799 | +154,799 | 23 | 3,904 | 0.79% | +3,882 |
| VIKING THERAPEUTICS INC(VKTX) | 14,401 | 91,227 | +76,826 | 1,181 | 4,836 | 0.97% | +3,655 |
| CRINETICS PHARMACEUTICALS IN(CRNX) | 0 | 74,850 | +74,850 | 0 | 3,353 | 0.68% | +3,353 |
| INSMED INC(INSM) | 0 | 42,217 | +42,217 | 0 | 2,829 | 0.57% | +2,829 |
| CEREVEL THERAPEUTICS HLDNG I | 24,259 | 93,350 | +69,091 | 1,025 | 3,817 | 0.77% | +2,792 |
| KEROS THERAPEUTICS INC(KROS) | 338,243 | 548,916 | +210,673 | 22,392 | 25,085 | 5.05% | +2,694 |
| SAVARA INC(SVRA) | 5,600 | 663,598 | +657,998 | 28 | 2,674 | 0.54% | +2,646 |
| KALA BIO INC(KALA) | 0 | 306,067 | +306,067 | 0 | 2,170 | 0.44% | +2,170 |
| KINIKSA PHARMACEUTICALS INTL(KNSA) | 0 | 114,309 | +114,309 | 0 | 2,134 | 0.43% | +2,134 |
| ACASTI PHARMA INC | 217,381 | 959,571 | +742,190 | 745 | 2,802 | 0.56% | +2,057 |
| ABSCI CORPORATION | 586,984 | 1,698,529 | +1,111,545 | 3,334 | 5,231 | 1.05% | +1,897 |
| BEAM THERAPEUTICS INC(BEAM) | 0 | 72,800 | +72,800 | 0 | 1,706 | 0.34% | +1,706 |
| SOLENO THERAPEUTICS INC | 0 | 39,929 | +39,929 | 0 | 1,629 | 0.33% | +1,629 |
| MERUS N V | 0 | 26,850 | +26,850 | 0 | 1,589 | 0.32% | +1,589 |
| AURA BIOSCIENCES INC(AURA) | 0 | 203,237 | +203,237 | 0 | 1,536 | 0.31% | +1,536 |
| APOGEE THERAPEUTICS INC(APGE) | 6,000 | 40,875 | +34,875 | 399 | 1,608 | 0.32% | +1,210 |
| ASTRIA THERAPEUTICS INC | 4,652 | 138,158 | +133,506 | 65 | 1,257 | 0.25% | +1,192 |
| CONTEXT THERAPEUTICS INC(CNTX) | 205,934 | 645,161 | +439,227 | 284 | 1,294 | 0.26% | +1,009 |
| TARGET HOSPITALITY CORP(TH) | 0 | 113,626 | +113,626 | 0 | 990 | 0.20% | +990 |
| VIR BIOTECHNOLOGY INC(VIR) | 0 | 110,000 | +110,000 | 0 | 979 | 0.20% | +979 |
| CULLINAN THERAPEUTICS INC(CGEM) | 0 | 53,261 | +53,261 | 0 | 929 | 0.19% | +929 |
| ITEOS THERAPEUTICS INC | 0 | 60,000 | +60,000 | 0 | 890 | 0.18% | +890 |
| KYMERA THERAPEUTICS INC(KYMR) | 16,000 | 50,626 | +34,626 | 643 | 1,511 | 0.30% | +868 |
| DENALI THERAPEUTICS INC(DNLI) | 2,000 | 38,000 | +36,000 | 41 | 882 | 0.18% | +841 |
| AVANGRID INC | 0 | 23,000 | +23,000 | 0 | 817 | 0.16% | +817 |
| VAXCYTE INC(PCVX) | 2,000 | 12,250 | +10,250 | 137 | 925 | 0.19% | +788 |
| KIORA PHARMACEUTICALS INC(KPRX) | 0 | 172,596 | +172,596 | 0 | 725 | 0.15% | +725 |
| PERSPECTIVE THERAPEUTICS INC(CATX) | 0 | 69,985 | +69,985 | 0 | 698 | 0.14% | +698 |
| ELIEM THERAPEUTICS INC(CLYM) | 0 | 97,695 | +97,695 | 0 | 695 | 0.14% | +695 |
| GUARDANT HEALTH INC(GH) | 17,000 | 34,000 | +17,000 | 351 | 982 | 0.20% | +631 |
| VAXART INC(VXRT) | 0 | 945,568 | +945,568 | 0 | 631 | 0.13% | +631 |
| DELCATH SYS INC(DCTH) | 218,973 | 198,347 | -20,626 | 1,045 | 1,660 | 0.33% | +616 |
| ALECTOR INC | 52,500 | 195,311 | +142,811 | 316 | 887 | 0.18% | +571 |
| AKERO THERAPEUTICS INC | 1,807 | 25,507 | +23,700 | 46 | 598 | 0.12% | +553 |
| INDIVIOR PLC | 27,601 | 70,007 | +42,406 | 591 | 1,129 | 0.23% | +537 |
| ARDELYX INC | 0 | 70,000 | +70,000 | 0 | 519 | 0.10% | +519 |
| ALKERMES PLC(ALKS) | 156,600 | 196,577 | +39,977 | 4,239 | 4,738 | 0.95% | +498 |
| DAY ONE BIOPHARMACEUTICALS I COM | 0 | 35,100 | +35,100 | 0 | 484 | 0.10% | +484 |
| ABEONA THERAPEUTICS INC(ABEO) | 0 | 113,125 | +113,125 | 0 | 480 | 0.10% | +480 |
| POLYPID LTD(PYPD) | 0 | 103,950 | +103,950 | 0 | 447 | 0.09% | +447 |
| KEZAR LIFE SCIENCES INC | 236,623 | 1,086,498 | +849,875 | 213 | 652 | 0.13% | +439 |
| TAYSHA GENE THERAPIES INC(TSHA) | 43,500 | 250,800 | +207,300 | 125 | 562 | 0.11% | +437 |
| RENOVORX INC(RNXT) | 0 | 355,240 | +355,240 | 0 | 401 | 0.08% | +401 |
| TRIPADVISOR INC(TRIP) | 0 | 22,000 | +22,000 | 0 | 392 | 0.08% | +392 |
| MOVANO INC | 0 | 1,407,000 | +1,407,000 | 0 | 387 | 0.08% | +387 |
| GERON CORP(GERN) | 1,295 | 90,000 | +88,705 | 4 | 382 | 0.08% | +377 |
| CYTOMX THERAPEUTICS INC(CTMX) | 155,000 | 572,170 | +417,170 | 338 | 698 | 0.14% | +360 |
| GRAIL INC(GRAL) | 0 | 21,401 | +21,401 | 0 | 329 | 0.07% | +329 |
| ARCA BIOPHARMA INC | 0 | 84,676 | +84,676 | 0 | 324 | 0.07% | +324 |
| CG ONCOLOGY INC(CGON) | 2,050 | 12,850 | +10,800 | 90 | 406 | 0.08% | +316 |
| MKS INSTRS INC(MKSI) | 0 | 2,000 | +2,000 | 0 | 261 | 0.05% | +261 |
| KORRO BIO INC(KRRO) | 0 | 7,210 | +7,210 | 0 | 244 | 0.05% | +244 |
| TEVA PHARMACEUTICAL INDS LTD(TEVA) | 101,626 | 103,121 | +1,495 | 1,434 | 1,676 | 0.34% | +242 |
| OMNIAB INC(OABI) | 451,485 | 712,560 | +261,075 | 2,447 | 2,672 | 0.54% | +225 |
| OCULAR THERAPEUTIX INC(OCUL) | 0 | 32,900 | +32,900 | 0 | 225 | 0.05% | +225 |
| OLEMA PHARMACEUTICALS INC(OLMA) | 0 | 20,076 | +20,076 | 0 | 217 | 0.04% | +217 |
| VERVE THERAPEUTICS INC | 0 | 44,000 | +44,000 | 0 | 215 | 0.04% | +215 |
| MEREO BIOPHARMA GROUP PLC(MREO) | 0 | 55,400 | +55,400 | 0 | 199 | 0.04% | +199 |
| WAVE LIFE SCIENCES LTD(WVE) | 30,000 | 76,651 | +46,651 | 185 | 382 | 0.08% | +197 |
| ELEVATION ONCOLOGY INC | 8,629 | 84,927 | +76,298 | 44 | 229 | 0.05% | +185 |
| ABBOTT LABS | 1,400 | 3,300 | +1,900 | 159 | 343 | 0.07% | +184 |
| XENON PHARMACEUTICALS INC(XENE) | 0 | 4,700 | +4,700 | 0 | 183 | 0.04% | +183 |
| BIOCRYST PHARMACEUTICALS INC(BCRX) | 0 | 29,400 | +29,400 | 0 | 182 | 0.04% | +182 |
| SANOFI(SNY) | 5,500 | 9,100 | +3,600 | 267 | 442 | 0.09% | +174 |
| CHIMERIX INC | 0 | 178,229 | +178,229 | 0 | 156 | 0.03% | +156 |
| ARYA SCIENCES ACQU CORP IV | 40,930 | 53,527 | +12,597 | 460 | 614 | 0.12% | +154 |
| RELMADA THERAPEUTICS INC(RLMD) | 601 | 50,601 | +50,000 | 3 | 152 | 0.03% | +149 |
| ABIVAX SA(ABVX) | 15,000 | 27,000 | +12,000 | 215 | 357 | 0.07% | +142 |
| ARROWHEAD PHARMACEUTICALS IN(ARWR) | 600 | 5,900 | +5,300 | 17 | 153 | 0.03% | +136 |
| BOLT BIOTHERAPEUTICS INC | 5,000 | 185,999 | +180,999 | 7 | 139 | 0.03% | +132 |
| EAGLE PHARMACEUTICALS INC | 0 | 22,000 | +22,000 | 0 | 123 | 0.02% | +123 |
| ACELYRIN INC | 15,021 | 50,521 | +35,500 | 101 | 223 | 0.04% | +121 |
| PLIANT THERAPEUTICS INC(PLRX) | 0 | 10,000 | +10,000 | 0 | 108 | 0.02% | +108 |
| IOVANCE BIOTHERAPEUTICS INC(IOVA) | 5,000 | 22,400 | +17,400 | 74 | 180 | 0.04% | +106 |
| SCHOLAR ROCK HLDG CORP(SRRK) | 0 | 12,000 | +12,000 | 0 | 100 | 0.02% | +100 |
| OPTION CARE HEALTH INC(OPCH) | 7,000 | 12,000 | +5,000 | 235 | 332 | 0.07% | +98 |
| AMYLYX PHARMACEUTICALS INC(AMLX) | 38,858 | 107,306 | +68,448 | 110 | 204 | 0.04% | +94 |
| TERNS PHARMACEUTICALS INC | 5,000 | 15,000 | +10,000 | 33 | 102 | 0.02% | +69 |
| PMV PHARMACEUTICALS INC(PMVP) | 10,000 | 50,000 | +40,000 | 17 | 81 | 0.02% | +64 |
| MOONLAKE IMMUNOTHERAPEUTICS(MLTX) | 3,000 | 4,800 | +1,800 | 151 | 211 | 0.04% | +60 |
| VIRIDIAN THERAPEUTICS INC(VRDN) | 2,550 | 8,000 | +5,450 | 45 | 104 | 0.02% | +59 |
| NEXTCURE INC | 43,014 | 89,014 | +46,000 | 96 | 142 | 0.03% | +46 |
| CASI PHARMACEUTICALS INC(CASIF) | 0 | 8,240 | +8,240 | 0 | 45 | 0.01% | +45 |
| QUINCE THERAPEUTICS INC(QNCX) | 26,829 | 92,958 | +66,129 | 28 | 70 | 0.01% | +41 |
| CARA THERAPEUTICS INC | 0 | 159,469 | +159,469 | 0 | 41 | 0.01% | +41 |