Securities ▲▼ | Shares | Value ($K) | |||||
|---|---|---|---|---|---|---|---|
Q3 2024 ▲▼ | Q4 2024 ▲▼ | Change ▲▼ | Q3 2024 ▲▼ | Q4 2024 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| INHIBIKASE THERAPEUTICS INC(IKT) | 0 | 5,103,005 | +5,103,005 | 0 | 16,585 | 3.42% | +16,585 |
| ZAI LAB LTD(ZLAB) | 532,454 | 1,045,837 | +513,383 | 12,853 | 27,390 | 5.65% | +14,537 |
| SPDR SER TR ST STR BLO 1 ETF | 21,786 | 131,786 | +110,000 | 2,000 | 12,049 | 2.48% | +10,049 |
| ROIVANT SCIENCES LTD(ROIV) | 3,025,450 | 3,508,694 | +483,244 | 34,914 | 41,508 | 8.55% | +6,594 |
| ANTERIS TECHNOLOGIES GLOBAL(AVR) | 0 | 1,052,968 | +1,052,968 | 0 | 5,876 | 1.21% | +5,876 |
| COHERUS BIOSCIENCES INC(CHRS) | 0 | 0 | 0 | 0 | 5,478 | 1.13% | +5,478 |
| REVOLUTION MEDICINES INC(RVMD) | 44,351 | 170,000 | +125,649 | 2,011 | 7,436 | 1.53% | +5,424 |
| ABIVAX SA(ABVX) | 521,612 | 1,513,393 | +991,781 | 6,009 | 11,078 | 2.28% | +5,069 |
| OAKTREE ACQUISITION CORP III UNIT 10/04/2029 | 0 | 500,000 | +500,000 | 0 | 5,065 | 1.04% | +5,065 |
| SANOFI(SNY) | 0 | 99,600 | +99,600 | 0 | 4,804 | 0.99% | +4,804 |
| GOSSAMER BIO INC(GOSS) | 0 | 0 | 0 | 0 | 4,355 | 0.90% | +4,355 |
| 89BIO INC | 6,560 | 515,138 | +508,578 | 49 | 4,028 | 0.83% | +3,980 |
| SAREPTA THERAPEUTICS INC(SRPT) | 7,100 | 40,002 | +32,902 | 887 | 4,864 | 1.00% | +3,977 |
| BRIDGEBIO PHARMA INC(BBIO) | 0 | 0 | 0 | 0 | 3,861 | 0.80% | +3,861 |
| ENDEAVOR GROUP HLDGS INC | 122,807 | 210,729 | +87,922 | 3,507 | 6,594 | 1.36% | +3,086 |
| MONOPAR THERAPEUTICS INC(MNPR) | 0 | 130,037 | +130,037 | 0 | 2,861 | 0.59% | +2,861 |
| ROCKET PHARMACEUTICALS INC(RCKT) | 4,300 | 211,400 | +207,100 | 79 | 2,657 | 0.55% | +2,578 |
| AEROVATE THERAPEUTICS INC | 113,075 | 928,016 | +814,941 | 236 | 2,459 | 0.51% | +2,223 |
| CENTESSA PHARMACEUTICALS PLC | 23,302 | 154,027 | +130,725 | 373 | 2,580 | 0.53% | +2,207 |
| A SPAC III ACQUISITION CORP UNIT 02/15/2029 | 0 | 215,000 | +215,000 | 0 | 2,165 | 0.45% | +2,165 |
| BRIDGEBIO PHARMA INC(BBIO) | 0 | 0 | 0 | 0 | 2,104 | 0.43% | +2,104 |
| RAPT THERAPEUTICS INC | 7,500 | 1,174,313 | +1,166,813 | 15 | 1,855 | 0.38% | +1,840 |
| PALVELLA THERAPEUTICS INC NE(PVLA) | 0 | 144,641 | +144,641 | 0 | 1,736 | 0.36% | +1,736 |
| RHYTHM PHARMACEUTICALS INC(RYTM) | 0 | 30,941 | +30,941 | 0 | 1,732 | 0.36% | +1,732 |
| AXSOME THERAPEUTICS INC(AXSM) | 600 | 19,661 | +19,061 | 54 | 1,664 | 0.34% | +1,610 |
| ALDEYRA THERAPEUTICS INC(ALDX) | 302,212 | 647,960 | +345,748 | 1,629 | 3,233 | 0.67% | +1,604 |
| MINERALYS THERAPEUTICS INC(MLYS) | 729,401 | 841,541 | +112,140 | 8,833 | 10,359 | 2.14% | +1,526 |
| DELCATH SYS INC(DCTH) | 31,052 | 149,385 | +118,333 | 280 | 1,799 | 0.37% | +1,518 |
| AVID BIOSERVICES INC | 0 | 120,000 | +120,000 | 0 | 1,482 | 0.31% | +1,482 |
| PTC THERAPEUTICS INC(PTCT) | 20,000 | 48,023 | +28,023 | 742 | 2,168 | 0.45% | +1,426 |
| POSEIDA THERAPEUTICS INC | 0 | 134,109 | +134,109 | 0 | 1,287 | 0.27% | +1,287 |
| TEVA PHARMACEUTICAL INDS LTD(TEVA) | 108,171 | 146,671 | +38,500 | 1,949 | 3,233 | 0.67% | +1,283 |
| INSMED INC(INSM) | 3,634 | 21,974 | +18,340 | 265 | 1,517 | 0.31% | +1,252 |
| ALPHA COGNITION INC(ACOG) | 0 | 204,348 | +204,348 | 0 | 1,204 | 0.25% | +1,204 |
| SOLENO THERAPEUTICS INC | 10,000 | 36,830 | +26,830 | 505 | 1,656 | 0.34% | +1,151 |
| ACELYRIN INC | 53,500 | 444,967 | +391,467 | 264 | 1,397 | 0.29% | +1,133 |
| JANUX THERAPEUTICS INC(JANX) | 13,000 | 31,509 | +18,509 | 591 | 1,687 | 0.35% | +1,096 |
| VERONA PHARMA PLC | 10,000 | 29,100 | +19,100 | 288 | 1,351 | 0.28% | +1,064 |
| CONTINEUM THERAPEUTICS INC(CTNM) | 8,967 | 82,234 | +73,267 | 172 | 1,205 | 0.25% | +1,033 |
| STRUCTURE THERAPEUTICS INC | 0 | 35,319 | +35,319 | 0 | 958 | 0.20% | +958 |
| DANAHER CORPORATION(DHR) | 0 | 4,000 | +4,000 | 0 | 918 | 0.19% | +918 |
| XENON PHARMACEUTICALS INC(XENE) | 27,903 | 50,547 | +22,644 | 1,099 | 1,981 | 0.41% | +883 |
| CG ONCOLOGY INC(CGON) | 143,104 | 215,750 | +72,646 | 5,399 | 6,188 | 1.28% | +788 |
| SCHOLAR ROCK HLDG CORP(SRRK) | 12,000 | 19,505 | +7,505 | 96 | 843 | 0.17% | +747 |
| NEUMORA THERAPEUTICS INC.(NMRA) | 0 | 68,608 | +68,608 | 0 | 727 | 0.15% | +727 |
| FULCRUM THERAPEUTICS INC(FULC) | 55,802 | 196,248 | +140,446 | 199 | 922 | 0.19% | +723 |
| BIOAGE LABS INC(BIOA) | 0 | 123,037 | +123,037 | 0 | 712 | 0.15% | +712 |
| ALNYLAM PHARMACEUTICALS INC(ALNY) | 0 | 2,900 | +2,900 | 0 | 682 | 0.14% | +682 |
| CIDARA THERAPEUTICS INC | 0 | 24,938 | +24,938 | 0 | 670 | 0.14% | +670 |
| EA SERIES TRUST ALPHA ARCH 1-3 | 323,382 | 325,450 | +2,068 | 35,226 | 35,891 | 7.40% | +665 |
| PROTARA THERAPEUTICS INC(TARA) | 0 | 122,690 | +122,690 | 0 | 648 | 0.13% | +648 |
| LEXEO THERAPEUTICS INC(LXEO) | 57,166 | 169,505 | +112,339 | 517 | 1,115 | 0.23% | +599 |
| KORRO BIO INC(KRRO) | 49,451 | 57,978 | +8,527 | 1,653 | 2,207 | 0.45% | +555 |
| ORGANON & CO(OGN) | 3,100 | 40,200 | +37,100 | 59 | 600 | 0.12% | +540 |
| SCHRODINGER INC(SDGR) | 0 | 25,147 | +25,147 | 0 | 485 | 0.10% | +485 |
| VOYAGER THERAPEUTICS INC(VYGR) | 40,634 | 126,792 | +86,158 | 238 | 719 | 0.15% | +481 |
| PHATHOM PHARMACEUTICALS INC(PHAT) | 200 | 55,400 | +55,200 | 4 | 450 | 0.09% | +446 |
| CAPRICOR THERAPEUTICS INC(CAPR) | 24,307 | 56,120 | +31,813 | 370 | 774 | 0.16% | +405 |
| MODERNA INC(MRNA) | 0 | 9,000 | +9,000 | 0 | 374 | 0.08% | +374 |
| ATEA PHARMACEUTICALS INC(AVIR) | 0 | 110,000 | +110,000 | 0 | 369 | 0.08% | +369 |
| ULTRAGENYX PHARMACEUTICAL IN(RARE) | 0 | 8,000 | +8,000 | 0 | 337 | 0.07% | +337 |
| BEIGENE LTD(ONC) | 978 | 2,974 | +1,996 | 220 | 549 | 0.11% | +330 |
| LEAP THERAPEUTICS INC(CYPH) | 0 | 106,000 | +106,000 | 0 | 305 | 0.06% | +305 |
| VIRIDIAN THERAPEUTICS INC(VRDN) | 9,206 | 26,000 | +16,794 | 209 | 498 | 0.10% | +289 |
| ALVOTECH(ALVO) | 0 | 20,600 | +20,600 | 0 | 273 | 0.06% | +273 |
| WAVE LIFE SCIENCES LTD(WVE) | 0 | 21,700 | +21,700 | 0 | 268 | 0.06% | +268 |
| KODIAK SCIENCES INC(KOD) | 0 | 23,700 | +23,700 | 0 | 236 | 0.05% | +236 |
| INOZYME PHARMA INC | 0 | 76,299 | +76,299 | 0 | 211 | 0.04% | +211 |
| NURIX THERAPEUTICS INC(NRIX) | 0 | 11,000 | +11,000 | 0 | 207 | 0.04% | +207 |
| CHIMERIX INC | 240,557 | 122,236 | -118,321 | 224 | 425 | 0.09% | +202 |
| PULMONX CORP(LUNG) | 0 | 28,221 | +28,221 | 0 | 192 | 0.04% | +192 |
| GINKGO BIOWORKS HOLDINGS INC(DNA) | 0 | 18,680 | +18,680 | 0 | 183 | 0.04% | +183 |
| UNIQURE NV(QURE) | 0 | 10,000 | +10,000 | 0 | 177 | 0.04% | +177 |
| ANAVEX LIFE SCIENCES CORP | 0 | 16,221 | +16,221 | 0 | 174 | 0.04% | +174 |
| MIND MEDICINE MINDMED INC | 0 | 25,000 | +25,000 | 0 | 174 | 0.04% | +174 |
| ACUMEN PHARMACEUTICALS INC(ABOS) | 0 | 94,294 | +94,294 | 0 | 162 | 0.03% | +162 |
| QUINCE THERAPEUTICS INC(QNCX) | 142,958 | 142,958 | 0 | 111 | 267 | 0.06% | +156 |
| INDIVIOR PLC | 54,057 | 54,057 | 0 | 527 | 672 | 0.14% | +145 |
| KALVISTA PHARMACEUTICALS INC | 14,143 | 35,843 | +21,700 | 164 | 304 | 0.06% | +140 |
| ATAI LIFE SCIENCES NV | 0 | 100,000 | +100,000 | 0 | 133 | 0.03% | +133 |
| PERCEPTIVE CAP SOLUTIONS COR CL A ORD SHS | 750,000 | 750,000 | 0 | 7,515 | 7,635 | 1.57% | +120 |
| MERCK & CO INC(MRK) | 1,140 | 2,440 | +1,300 | 129 | 243 | 0.05% | +113 |
| ARDELYX INC | 6,400 | 31,035 | +24,635 | 44 | 157 | 0.03% | +113 |
| LYRA THERAPEUTICS INC | 0 | 533,200 | +533,200 | 0 | 110 | 0.02% | +110 |
| OVID THERAPEUTICS INC(OVID) | 37,743 | 130,532 | +92,789 | 45 | 122 | 0.03% | +77 |
| ALLAKOS INC | 0 | 62,264 | +62,264 | 0 | 75 | 0.02% | +75 |
| GLYCOMIMETICS INC | 45,700 | 331,827 | +286,127 | 8 | 83 | 0.02% | +75 |
| CLOVER HEALTH INVESTMENTS CO(CLOV) | 0 | 23,300 | +23,300 | 0 | 73 | 0.02% | +73 |
| ELEDON PHARMACEUTICALS INC(ELDN) | 0 | 16,000 | +16,000 | 0 | 66 | 0.01% | +66 |
| VENTYX BIOSCIENCES INC | 97,955 | 124,530 | +26,575 | 214 | 273 | 0.06% | +59 |
| PROQR THRAPEUTICS N V SHS EURO | 0 | 20,394 | +20,394 | 0 | 54 | 0.01% | +54 |
| REGENERON PHARMACEUTICALS(REGN) | 871 | 1,361 | +490 | 916 | 969 | 0.20% | +54 |
| ACHIEVE LIFE SCIENCES INC | 91 | 13,173 | +13,082 | 0 | 46 | 0.01% | +46 |
| ELI LILLY & CO(LLY) | 1,150 | 1,350 | +200 | 1,019 | 1,042 | 0.21% | +23 |
| ARES ACQUISITION CORP II | 138,966 | 138,966 | 0 | 1,505 | 1,526 | 0.31% | +21 |
| HELIX ACQUISITION CORP II | 404,138 | 404,138 | 0 | 4,223 | 4,243 | 0.87% | +20 |
| KEEN VISION ACQUISITION CORP(KVACF) | 75,000 | 75,000 | 0 | 805 | 824 | 0.17% | +20 |
| ARROWHEAD PHARMACEUTICALS IN(ARWR) | 11,705 | 12,900 | +1,195 | 227 | 243 | 0.05% | +16 |
| GRACE THERAPEUTICS INC(GRCE) | 959,571 | 773,635 | -185,936 | 2,879 | 2,893 | 0.60% | +15 |
| KARYOPHARM THERAPEUTICS INC(KPTI) | 0 | 20,000 | +20,000 | 0 | 14 | 0.00% | +14 |