Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q3 2025 ▲▼ | Q4 2025 ▲▼ | Change ▲▼ | Q3 2025 ▲▼ | Q4 2025 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| ABIVAX Société AnonymeADS(ABVX) | 1,350,826 | 1,317,329 | -33,497 | $114.69M | $177.65M | 13.29% | +$62.96M |
| Protagonist Therapeutics Inc | 989,182 | 1,049,168 | +59,986 | $65.71M | $91.63M | 6.85% | +$25.92M |
| Roivant Sciences Ltd.SHS(ROIV) | 3,347,501 | 3,428,962 | +81,461 | $50.65M | $74.41M | 5.57% | +$23.76M |
| Immunovant, Inc.(IMVT) | 2,241,753 | 2,480,968 | +239,215 | $36.14M | $63.07M | 4.72% | +$26.93M |
| Avidity Biosciences Inc | 53,656 | 546,534 | +492,878 | $2.34M | $39.42M | 2.95% | +$37.08M |
| Ea Series TrustALPHA ARCH 1 3 ALPHA ARCH 1-3 | 337,125 | 337,125 | 0 | $38.39M | $38.80M | 2.90% | +$418.0K |
| State Street SPDR S&P 500 ETF TrustTR UNIT(SPY) | 54,684 | 54,684 | 0 | $36.43M | $37.29M | 2.79% | +$860.7K |
| Cytokinetics, Incorporated(CYTK) | 518,921 | 540,166 | +21,245 | $28.52M | $34.32M | 2.57% | +$5.80M |
| Septerna, Inc.(SEPN) | 1,176,491 | 1,157,611 | -18,880 | $22.13M | $32.27M | 2.41% | +$10.14M |
| Arbutus Biopharma Corporation(ABUS) | 2,903,226 | 5,415,109 | +2,511,883 | $13.18M | $26.05M | 1.95% | +$12.87M |
| Zai Lab LimitedADR(ZLAB) | 868,780 | 1,246,520 | +377,740 | $29.44M | $21.99M | 1.64% | -$7.45M |
| Terns Pharmaceuticals Inc | 10,000 | 541,615 | +531,615 | $75.1K | $21.88M | 1.64% | +$21.81M |
| CytomX Therapeutics, Inc.(CTMX) | 4,045,414 | 4,182,769 | +137,355 | $12.90M | $17.82M | 1.33% | +$4.91M |
| Celldex Therapeutics, Inc.(CLDX) | 109,442 | 646,767 | +537,325 | $2.83M | $17.57M | 1.31% | +$14.73M |
| Rapt Therapeutics Inc | 507,771 | 509,679 | +1,908 | $13.10M | $17.26M | 1.29% | +$4.17M |
| Inhibikase Therapeutics, Inc.(IKT) | 5,247,603 | 8,063,949 | +2,816,346 | $8.50M | $16.53M | 1.24% | +$8.03M |
| BridgeBio Pharma, Inc.(BBIO) | 273,414 | 213,414 | -60,000 | $14.20M | $16.32M | 1.22% | +$2.12M |
| Monopar Therapeutics Inc.(MNPR) | 129,999 | 233,908 | +103,909 | $10.62M | $15.27M | 1.14% | +$4.66M |
| Vaxcyte, Inc.(PCVX) | 213,064 | 315,642 | +102,578 | $7.67M | $14.56M | 1.09% | +$6.89M |
| Crinetics Pharmaceuticals In | 248,368 | 309,368 | +61,000 | $10.34M | $14.40M | 1.08% | +$4.06M |
| Fulcrum Therapeutics, Inc.(FULC) | 341,612 | 1,253,749 | +912,137 | $3.14M | $14.18M | 1.06% | +$11.04M |
| Prothena Corp PlcSHS SHS | 1,469,098 | 1,457,764 | -11,334 | $14.34M | $13.92M | 1.04% | -$416.8K |
| Lexeo Therapeutics, Inc.(LXEO) | 1,531,953 | 1,393,161 | -138,792 | $10.17M | $13.83M | 1.03% | +$3.66M |
| Taysha Gene Therapies, Inc.(TSHA) | 2,835,680 | 2,495,809 | -339,871 | $9.27M | $13.73M | 1.03% | +$4.45M |
| Cidara Therapeutics Inc | 21,522 | 59,677 | +38,155 | $2.06M | $13.18M | 0.99% | +$11.12M |
| Inventiva S.A.ADS(IVA) | 0 | 2,709,846 | +2,709,846 | $0 | $12.60M | 0.94% | +$12.60M |
| Establishment Labs Holdings Inc.(ESTA) | 90,688 | 171,422 | +80,734 | $3.72M | $12.49M | 0.93% | +$8.78M |
| Spdr Series TrustSTATE STREET SPD ST STR BLO 1 ETF | 135,585 | 135,585 | 0 | $12.44M | $12.39M | 0.93% | -$50.2K |
| Replimune Group, Inc.(REPL) | 978,894 | 1,241,322 | +262,428 | $4.10M | $12.07M | 0.90% | +$7.96M |
| Ionis Pharmaceuticals, Inc.(IONS) | 133,818 | 147,130 | +13,312 | $8.75M | $11.64M | 0.87% | +$2.89M |
| Revolution Medicines, Inc.(RVMD) | 139,136 | 145,079 | +5,943 | $6.50M | $11.56M | 0.86% | +$5.06M |
| Amylyx Pharmaceuticals, Inc.(AMLX) | 866,202 | 890,356 | +24,154 | $11.77M | $10.76M | 0.80% | -$1.02M |
| CG Oncology, Inc.(CGON) | 248,917 | 258,139 | +9,222 | $10.03M | $10.72M | 0.80% | +$691.6K |
| Teleflex Incorporated(TFX) | 0 | 80,627 | +80,627 | $0 | $9.84M | 0.74% | +$9.84M |
| Invivyd, Inc.(IVVD) | 7,370,987 | 3,899,397 | -3,471,590 | $8.11M | $9.63M | 0.72% | +$1.52M |
| Regeneron Pharmaceuticals, Inc.(REGN) | 15,700 | 12,051 | -3,649 | $8.83M | $9.30M | 0.70% | +$474.2K |
| Xenon Pharmaceuticals Inc.(XENE) | 189,098 | 203,969 | +14,871 | $7.59M | $9.14M | 0.68% | +$1.55M |
| Equillium, Inc.(EQ) | 5,559,988 | 5,608,078 | +48,090 | $7.95M | $8.69M | 0.65% | +$741.7K |
| Savara Inc.(SVRA) | 1,988,288 | 1,405,452 | -582,836 | $7.10M | $8.47M | 0.63% | +$1.38M |
| Maze Therapeutics, Inc.(MAZE) | 26,045 | 179,532 | +153,487 | $675.3K | $7.44M | 0.56% | +$6.76M |
| Teva Pharmaceutical Industries LimitedADS(TEVA) | 267,816 | 235,971 | -31,845 | $5.41M | $7.36M | 0.55% | +$1.95M |
| Crescent Biopharma, Inc.(CBIO) | 0 | 606,000 | +606,000 | $0 | $7.19M | 0.54% | +$7.19M |
| Ovid Therapeutics Inc.(OVID) | 12,846 | 4,285,000 | +4,272,154 | $16.7K | $6.98M | 0.52% | +$6.97M |
| Belite Bio, IncADS(BLTE) | 0 | 39,839 | +39,839 | $0 | $6.37M | 0.48% | +$6.37M |
| Vertex Pharmaceuticals Incorporated(VRTX) | 7,000 | 13,716 | +6,716 | $2.74M | $6.22M | 0.47% | +$3.48M |
| Brighthouse Financial, Inc.(BHF) | 10,000 | 95,523 | +85,523 | $530.8K | $6.19M | 0.46% | +$5.66M |
| Anteris Technologies Global Corp.(AVR) | 197,615 | 1,238,777 | +1,041,162 | $889.3K | $6.18M | 0.46% | +$5.29M |
| Aa Mission Acquisition CorpCL A | 578,359 | 578,359 | 0 | $6.08M | $6.17M | 0.46% | +$86.8K |
| Protara Therapeutics, Inc.(TARA) | 35,223 | 1,136,799 | +1,101,576 | $153.2K | $6.06M | 0.45% | +$5.91M |
| Perceptive Cap Solutions CorCL A CL A ORD SHS | 750,000 | 456,720 | -293,280 | $7.92M | $5.95M | 0.45% | -$1.97M |
| Danaher Corporation(DHR) | 0 | 25,600 | +25,600 | $0 | $5.86M | 0.44% | +$5.86M |
| Climb Bio, Inc.(CLYM) | 133,530 | 1,432,475 | +1,298,945 | $268.4K | $5.73M | 0.43% | +$5.46M |
| uniQure N.V.SHS(QURE) | 133,316 | 235,155 | +101,839 | $7.78M | $5.63M | 0.42% | -$2.15M |
| Rhythm Pharmaceuticals, Inc.(RYTM) | 49,571 | 51,349 | +1,778 | $5.01M | $5.50M | 0.41% | +$490.2K |
| Oaktree Acquisition Corp IiiUNIT 10 04 2029 UNIT 10/04/2029 | 516,482 | 516,482 | 0 | $5.48M | $5.49M | 0.41% | +$5.2K |
| Ascendis Pharma A/SADR(ASND) | 36,345 | 25,314 | -11,031 | $7.23M | $5.40M | 0.40% | -$1.83M |
| Agios Pharmaceuticals, Inc.(AGIO) | 37,000 | 188,000 | +151,000 | $1.49M | $5.12M | 0.38% | +$3.63M |
| Spruce Biosciences Inc | 0 | 58,000 | +58,000 | $0 | $5.05M | 0.38% | +$5.05M |
| Mineralys Therapeutics, Inc.(MLYS) | 78,238 | 136,231 | +57,993 | $2.97M | $4.94M | 0.37% | +$1.98M |
| Krystal Biotech, Inc.(KRYS) | 18,523 | 20,014 | +1,491 | $3.27M | $4.93M | 0.37% | +$1.66M |
| Palisade Bio, Inc.(PALI) | 0 | 2,004,845 | +2,004,845 | $0 | $4.71M | 0.35% | +$4.71M |
| ARS Pharmaceuticals, Inc.(SPRY) | 59,230 | 369,569 | +310,339 | $595.3K | $4.31M | 0.32% | +$3.71M |
| Biogen Inc.(BIIB) | 18,000 | 24,300 | +6,300 | $2.52M | $4.28M | 0.32% | +$1.76M |
| Newamsterdam Pharma Company ORDINARY SHARES | 114,359 | 118,623 | +4,264 | $3.25M | $4.16M | 0.31% | +$908.9K |
| American Exceptionalism AcquCL A ORD CL A | 50,000 | 357,539 | +307,539 | $546.5K | $4.07M | 0.30% | +$3.53M |
| Arrowhead Pharmaceuticals, Inc.(ARWR) | 49,800 | 58,200 | +8,400 | $1.72M | $3.86M | 0.29% | +$2.15M |
| Atai Beckley NvSHS | 913,242 | 913,242 | 0 | $4.83M | $3.74M | 0.28% | -$1.10M |
| Corvus Pharmaceuticals, Inc.(CRVS) | 0 | 465,875 | +465,875 | $0 | $3.59M | 0.27% | +$3.59M |
| Janux Therapeutics, Inc.(JANX) | 351,032 | 245,452 | -105,580 | $8.58M | $3.39M | 0.25% | -$5.19M |
| Monte Rosa Therapeutics, Inc.(GLUE) | 215,752 | 215,752 | 0 | $1.60M | $3.38M | 0.25% | +$1.78M |
| Avadel Pharmaceuticals Plc | 0 | 150,532 | +150,532 | $0 | $3.24M | 0.24% | +$3.24M |
| Contineum Therapeutics, Inc.CL A(CTNM) | 77,961 | 278,961 | +201,000 | $916.0K | $3.19M | 0.24% | +$2.27M |
| Evommune, Inc.(EVMN) | 0 | 184,062 | +184,062 | $0 | $3.15M | 0.24% | +$3.15M |
| SanofiADR(SNY) | 74,212 | 63,474 | -10,738 | $3.50M | $3.08M | 0.23% | -$426.9K |
| Scholar Rock Holding Corporation(SRRK) | 20,087 | 69,589 | +49,502 | $748.0K | $3.07M | 0.23% | +$2.32M |
| Nektar Therapeutics(NKTR) | 72,007 | 72,031 | +24 | $4.10M | $3.05M | 0.23% | -$1.05M |
| Ishares TrRUSSELL 2000 ETF | 0 | 12,070 | +12,070 | $0 | $2.97M | 0.22% | +$2.97M |
| Zura Bio LimitedCL A(ZURA) | 652,154 | 562,065 | -90,089 | $2.82M | $2.95M | 0.22% | +$121.4K |
| OnKure Therapeutics, Inc.CL A(OKUR) | 0 | 1,014,158 | +1,014,158 | $0 | $2.94M | 0.22% | +$2.94M |
| UroGen Pharma Ltd.(URGN) | 35,000 | 125,375 | +90,375 | $698.3K | $2.94M | 0.22% | +$2.24M |
| LeonaBio, Inc.(LONA) | 0 | 393,701 | +393,701 | $0 | $2.89M | 0.22% | +$2.89M |
| BridgeBio Oncology Therapeutics, Inc.(BBOT) | 501,228 | 226,248 | -274,980 | $5.80M | $2.83M | 0.21% | -$2.97M |
| Eledon Pharmaceuticals, Inc.(ELDN) | 0 | 1,821,812 | +1,821,812 | $0 | $2.75M | 0.21% | +$2.75M |
| Engene Holdings Inc COM | 0 | 303,686 | +303,686 | $0 | $2.74M | 0.21% | +$2.74M |
| Dynavax Technologies Corp | 170,000 | 170,000 | 0 | $1.69M | $2.61M | 0.20% | +$926.5K |
| Inovio Pharmaceuticals, Inc.(INO) | 0 | 1,485,008 | +1,485,008 | $0 | $2.58M | 0.19% | +$2.58M |
| Viridian Therapeutics, Inc.(VRDN) | 101,704 | 77,198 | -24,506 | $2.19M | $2.40M | 0.18% | +$207.6K |
| Pharvaris N V COM | 34,124 | 85,528 | +51,404 | $851.4K | $2.37M | 0.18% | +$1.52M |
| Corbus Pharmaceuticals Holdings, Inc.(CRBP) | 10,200 | 286,781 | +276,581 | $129.0K | $2.33M | 0.17% | +$2.21M |
| Astria Therapeutics Inc | 193,934 | 173,557 | -20,377 | $1.41M | $2.27M | 0.17% | +$860.0K |
| Delcath Systems, Inc.(DCTH) | 224,385 | 224,385 | 0 | $2.41M | $2.27M | 0.17% | -$145.8K |
| Edgewise Therapeutics, Inc.(EWTX) | 40,000 | 90,999 | +50,999 | $648.8K | $2.26M | 0.17% | +$1.61M |
| Grace Therapeutics, Inc.(GRCE) | 350,450 | 641,988 | +291,538 | $1.04M | $2.22M | 0.17% | +$1.18M |
| REGENXBIO Inc.(RGNX) | 205,409 | 144,848 | -60,561 | $1.98M | $2.09M | 0.16% | +$103.6K |
| Arcellx Inc COMMON STOCK | 31,484 | 31,484 | 0 | $2.58M | $2.05M | 0.15% | -$532.1K |
| Olema Pharmaceuticals, Inc.(OLMA) | 36,200 | 81,399 | +45,199 | $354.4K | $2.03M | 0.15% | +$1.68M |
| Masimo Corp | 15,000 | 15,000 | 0 | $2.21M | $1.95M | 0.15% | -$262.4K |
| Cybin D/B/A Helus Pharma(HELP) | 33,278 | 238,390 | +205,112 | $196.0K | $1.95M | 0.15% | +$1.75M |
| Soleno Therapeutics Inc | 25,230 | 41,830 | +16,600 | $1.71M | $1.94M | 0.14% | +$231.2K |
| Acumen Pharmaceuticals, Inc.(ABOS) | 891,183 | 891,183 | 0 | $1.52M | $1.88M | 0.14% | +$356.5K |