Securities ▲▼ | Shares | Value ($K) | |||||
|---|---|---|---|---|---|---|---|
Q4 2023 ▲▼ | Q1 2024 ▲▼ | Change ▲▼ | Q4 2023 ▲▼ | Q1 2024 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| CRINETICS PHARMACEUTICALS IN(CRNX) | 249,575 | 619,789 | +370,214 | 8,880 | 29,012 | 7.75% | +20,132 |
| AUTOLUS THERAPEUTICS PLC(AUTL) | 451,375 | 2,965,721 | +2,514,346 | 2,907 | 18,921 | 5.06% | +16,014 |
| ARCUTIS BIOTHERAPEUTICS INC(ARQT) | 2,594,536 | 2,205,899 | -388,637 | 8,380 | 21,860 | 5.84% | +13,480 |
| ROIVANT SCIENCES LTD(ROIV) | 2,169,116 | 3,553,844 | +1,384,728 | 24,359 | 37,458 | 10.01% | +13,098 |
| APPLIED THERAPEUTICS INC | 907,152 | 2,017,016 | +1,109,864 | 3,039 | 13,716 | 3.66% | +10,677 |
| KALVISTA PHARMACEUTICALS INC | 423,174 | 1,161,060 | +737,886 | 5,184 | 13,770 | 3.68% | +8,586 |
| PYXIS ONCOLOGY INC(PYXS) | 0 | 1,794,195 | +1,794,195 | 0 | 7,643 | 2.04% | +7,643 |
| TARSUS PHARMACEUTICALS INC(TARS) | 30,990 | 222,253 | +191,263 | 628 | 8,079 | 2.16% | +7,451 |
| CABALETTA BIO INC(CABA) | 450,706 | 1,003,916 | +553,210 | 10,231 | 17,127 | 4.58% | +6,896 |
| IMMUNOVANT INC(IMVT) | 322,015 | 627,228 | +305,213 | 13,566 | 20,266 | 5.41% | +6,699 |
| TOURMALINE BIO INC | 0 | 274,219 | +274,219 | 0 | 6,280 | 1.68% | +6,280 |
| AMICUS THERAPEUTICS INC COM | 862,815 | 1,547,141 | +684,326 | 12,243 | 18,225 | 4.87% | +5,982 |
| ANAPTYSBIO INC | 45,000 | 269,548 | +224,548 | 964 | 6,070 | 1.62% | +5,106 |
| SOLENO THERAPEUTICS INC | 0 | 115,833 | +115,833 | 0 | 4,958 | 1.32% | +4,958 |
| JANUX THERAPEUTICS INC(JANX) | 0 | 121,642 | +121,642 | 0 | 4,580 | 1.22% | +4,580 |
| IDEAYA BIOSCIENCES INC(IDYA) | 0 | 87,393 | +87,393 | 0 | 3,835 | 1.02% | +3,835 |
| JASPER THERAPEUTICS INC(JSPR) | 0 | 129,211 | +129,211 | 0 | 3,794 | 1.01% | +3,794 |
| AVADEL PHARMACEUTICALS PLC | 0 | 223,660 | +223,660 | 0 | 3,778 | 1.01% | +3,778 |
| TAYSHA GENE THERAPIES INC(TSHA) | 0 | 1,087,785 | +1,087,785 | 0 | 3,122 | 0.83% | +3,122 |
| ELI LILLY & CO(LLY) | 15,067 | 15,067 | 0 | 8,783 | 11,722 | 3.13% | +2,939 |
| SYNDAX PHARMACEUTICALS INC(SNDX) | 1,094,494 | 1,100,988 | +6,494 | 23,652 | 26,204 | 7.00% | +2,551 |
| HELIX ACQUISITION CORP II | 0 | 200,000 | +200,000 | 0 | 2,080 | 0.56% | +2,080 |
| LARIMAR THERAPEUTICS INC(LRMR) | 783,172 | 740,877 | -42,295 | 3,563 | 5,623 | 1.50% | +2,060 |
| INSMED INC(INSM) | 173,579 | 272,448 | +98,869 | 5,379 | 7,392 | 1.97% | +2,012 |
| EFFECTOR THERAPEUTICS INC | 0 | 132,793 | +132,793 | 0 | 1,911 | 0.51% | +1,911 |
| NEWAMSTERDAM PHARMA COMPANY ORDINARY SHARES | 0 | 80,334 | +80,334 | 0 | 1,900 | 0.51% | +1,900 |
| CG ONCOLOGY INC(CGON) | 0 | 40,723 | +40,723 | 0 | 1,788 | 0.48% | +1,788 |
| ACHILLES THERAPEUTICS PLC | 0 | 1,385,750 | +1,385,750 | 0 | 1,732 | 0.46% | +1,732 |
| PRAXIS PRECISION MEDICINES I(PRAX) | 0 | 26,893 | +26,893 | 0 | 1,641 | 0.44% | +1,641 |
| ANNEXON INC(ANNX) | 607,100 | 605,117 | -1,983 | 2,756 | 4,339 | 1.16% | +1,582 |
| DIANTHUS THERAPEUTICS INC(DNTH) | 0 | 43,456 | +43,456 | 0 | 1,304 | 0.35% | +1,304 |
| FULCRUM THERAPEUTICS INC(FULC) | 376,573 | 407,108 | +30,535 | 2,542 | 3,843 | 1.03% | +1,301 |
| KYVERNA THERAPEUTICS INC(KYTX) | 0 | 41,000 | +41,000 | 0 | 1,018 | 0.27% | +1,018 |
| PROTARA THERAPEUTICS INC(TARA) | 0 | 168,442 | +168,442 | 0 | 675 | 0.18% | +675 |
| VISTAGEN THERAPEUTICS INC(VTGN) | 1,790,182 | 1,848,582 | +58,400 | 8,764 | 9,292 | 2.48% | +529 |
| CARGO THERAPEUTICS INC | 26,875 | 51,126 | +24,251 | 622 | 1,141 | 0.30% | +519 |
| ACELYRIN INC | 587,373 | 714,773 | +127,400 | 4,382 | 4,825 | 1.29% | +443 |
| BIOHAVEN LTD(BHVN) | 111,354 | 83,461 | -27,893 | 4,766 | 4,564 | 1.22% | -201 |
| SHATTUCK LABS INC(STTK) | 147,752 | 0 | -147,752 | 1,053 | 0 | — | -1,053 |
| AMYLYX PHARMACEUTICALS INC(AMLX) | 83,381 | 0 | -83,381 | 1,227 | 0 | — | -1,227 |
| OCULAR THERAPEUTIX INC(OCUL) | 279,648 | 0 | -279,648 | 1,247 | 0 | — | -1,247 |
| RAPT THERAPEUTICS INC | 58,450 | 0 | -58,450 | 1,452 | 0 | — | -1,452 |
| AMBRX BIOPHARMA INC | 126,101 | 0 | -126,101 | 1,796 | 0 | — | -1,796 |
| ARROWHEAD PHARMACEUTICALS IN(ARWR) | 59,038 | 0 | -59,038 | 1,807 | 0 | — | -1,807 |
| CYTOKINETICS INC(CYTK) | 24,111 | 0 | -24,111 | 2,013 | 0 | — | -2,013 |
| AC IMMUNE SA(ACIU) | 434,588 | 0 | -434,588 | 2,173 | 0 | — | -2,173 |
| EYEPOINT PHARMACEUTICALS INC(EYPT) | 95,732 | 0 | -95,732 | 2,212 | 0 | — | -2,212 |
| MORPHOSYS AG | 277,485 | 0 | -277,485 | 2,747 | 0 | — | -2,747 |
| JASPER THERAPEUTICS INC | 3,707,110 | 0 | -3,707,110 | 2,925 | 0 | — | -2,925 |
| NEUROCRINE BIOSCIENCES INC(NBIX) | 22,500 | 0 | -22,500 | 2,965 | 0 | — | -2,965 |
| KINIKSA PHARMACEUTICALS LTD | 183,102 | 0 | -183,102 | 3,212 | 0 | — | -3,212 |
| MERUS N V | 501,806 | 233,871 | -267,935 | 13,800 | 10,531 | 2.81% | -3,268 |
| FATE THERAPEUTICS INC(FATE) | 898,196 | 0 | -898,196 | 3,359 | 0 | — | -3,359 |
| ASTRIA THERAPEUTICS INC | 856,952 | 230,273 | -626,679 | 6,162 | 2,677 | 0.72% | -3,485 |
| DISC MEDICINE INC(IRON) | 125,429 | 60,129 | -65,300 | 7,245 | 3,744 | 1.00% | -3,501 |
| SCPHARMACEUTICALS INC | 567,211 | 0 | -567,211 | 3,556 | 0 | — | -3,556 |
| OLEMA PHARMACEUTICALS INC(OLMA) | 281,287 | 0 | -281,287 | 3,946 | 0 | — | -3,946 |
| CYMABAY THERAPEUTICS INC | 182,258 | 0 | -182,258 | 4,305 | 0 | — | -4,305 |
| 89BIO INC | 408,257 | 0 | -408,257 | 4,560 | 0 | — | -4,560 |
| ALPINE IMMUNE SCIENCES INC | 246,178 | 0 | -246,178 | 4,692 | 0 | — | -4,692 |
| ANI PHARMACEUTICALS INC(ANIP) | 85,382 | 0 | -85,382 | 4,708 | 0 | — | -4,708 |
| SPDR S&P 500 ETF TR(SPY) | 9,921 | 0 | -9,921 | 4,716 | 0 | — | -4,716 |
| MADRIGAL PHARMACEUTICALS INC(MDGL) | 20,444 | 0 | -20,444 | 4,730 | 0 | — | -4,730 |
| SAGE THERAPEUTICS INC | 218,319 | 0 | -218,319 | 4,731 | 0 | — | -4,731 |
| IMMATICS N.V(IMTX) | 1,020,214 | 491,926 | -528,288 | 10,743 | 5,170 | 1.38% | -5,573 |
| MOONLAKE IMMUNOTHERAPEUTICS(MLTX) | 167,851 | 90,647 | -77,204 | 10,137 | 4,553 | 1.22% | -5,583 |
| SPYRE THERAPEUTICS INC(SYRE) | 378,766 | 62,253 | -316,513 | 8,151 | 2,361 | 0.63% | -5,790 |
| LEGEND BIOTECH CORP(LEGN) | 104,650 | 0 | -104,650 | 6,297 | 0 | — | -6,297 |
| LANTHEUS HLDGS INC(LNTH) | 108,911 | 0 | -108,911 | 6,752 | 0 | — | -6,752 |
| TEVA PHARMACEUTICAL INDS LTD | 701,597 | 0 | -701,597 | 7,325 | 0 | — | -7,325 |
| ARCELLX INC COMMON STOCK | 313,604 | 140,267 | -173,337 | 17,405 | 9,756 | 2.61% | -7,649 |
| JOHNSON & JOHNSON(JNJ) | 61,011 | 0 | -61,011 | 9,563 | 0 | — | -9,563 |
| MERCK & CO INC(MRK) | 89,016 | 0 | -89,016 | 9,705 | 0 | — | -9,705 |
| ARGENX SE(ARGX) | 26,484 | 0 | -26,484 | 10,075 | 0 | — | -10,075 |
| BRIDGEBIO PHARMA INC(BBIO) | 253,948 | 0 | -253,948 | 10,252 | 0 | — | -10,252 |
| PROTAGONIST THERAPEUTICS INC | 513,681 | 0 | -513,681 | 11,779 | 0 | — | -11,779 |