Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q4 2025 ▲▼ | Q1 2026 ▲▼ | Change ▲▼ | Q4 2025 ▲▼ | Q1 2026 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| Scholar Rock Holding Corporation(SRRK) | 886,893 | 1,035,496 | +148,603 | $39.07M | $50.90M | 9.78% | +$11.84M |
| ABIVAX Société AnonymeADS(ABVX) | 391,783 | 313,791 | -77,992 | $52.83M | $34.94M | 6.72% | -$17.89M |
| Syndax Pharmaceuticals, Inc.(SNDX) | 1,339,379 | 1,215,743 | -123,636 | $28.14M | $28.40M | 5.46% | +$259.4K |
| Revolution Medicines, Inc.(RVMD) | 62,032 | 281,632 | +219,600 | $4.94M | $27.39M | 5.26% | +$22.45M |
| Immunovant, Inc.(IMVT) | 644,959 | 746,494 | +101,535 | $16.39M | $18.54M | 3.56% | +$2.15M |
| Praxis Precision Medicines, Inc.(PRAX) | 21,067 | 56,267 | +35,200 | $6.21M | $18.13M | 3.48% | +$11.92M |
| MBX Biosciences, Inc.(MBX) | 78,553 | 499,469 | +420,916 | $2.48M | $14.91M | 2.87% | +$12.43M |
| Mineralys Therapeutics, Inc.(MLYS) | 290,049 | 533,378 | +243,329 | $10.53M | $14.45M | 2.78% | +$3.92M |
| Enliven Therapeutics Inc | 0 | 363,438 | +363,438 | $0 | $14.25M | 2.74% | +$14.25M |
| CG Oncology, Inc.(CGON) | 0 | 205,622 | +205,622 | $0 | $13.92M | 2.67% | +$13.92M |
| Biohaven Ltd.(BHVN) | 0 | 1,594,491 | +1,594,491 | $0 | $13.49M | 2.59% | +$13.49M |
| Surrozen, Inc.(SRZN) | 619,766 | 525,639 | -94,127 | $12.67M | $13.46M | 2.59% | +$788.9K |
| Roivant Sciences Ltd.SHS(ROIV) | 966,698 | 385,800 | -580,898 | $20.98M | $10.69M | 2.05% | -$10.29M |
| EyePoint, Inc.(EYPT) | 353,849 | 810,764 | +456,915 | $6.46M | $10.45M | 2.01% | +$3.99M |
| Arcutis Biotherapeutics, Inc.(ARQT) | 224,740 | 413,792 | +189,052 | $6.53M | $9.75M | 1.87% | +$3.22M |
| Structure Therapeutics IncADS | 351,073 | 200,267 | -150,806 | $24.42M | $9.65M | 1.86% | -$14.76M |
| Amylyx Pharmaceuticals, Inc.(AMLX) | 565,140 | 669,685 | +104,545 | $6.83M | $9.31M | 1.79% | +$2.48M |
| Dyne Therapeutics, Inc.(DYN) | 835,200 | 506,075 | -329,125 | $16.34M | $9.18M | 1.76% | -$7.16M |
| Edgewise Therapeutics, Inc.(EWTX) | 360,876 | 290,864 | -70,012 | $8.96M | $9.16M | 1.76% | +$207.1K |
| Cytokinetics, Incorporated(CYTK) | 146,978 | 129,577 | -17,401 | $9.34M | $8.54M | 1.64% | -$798.6K |
| Spyre Therapeutics, Inc.(SYRE) | 32,377 | 167,606 | +135,229 | $1.06M | $8.45M | 1.62% | +$7.39M |
| Denali Therapeutics Inc.(DNLI) | 419,058 | 426,561 | +7,503 | $6.92M | $8.19M | 1.57% | +$1.27M |
| Xenon Pharmaceuticals Inc.(XENE) | 348,605 | 140,755 | -207,850 | $15.62M | $8.18M | 1.57% | -$7.44M |
| Celldex Therapeutics, Inc.(CLDX) | 0 | 254,267 | +254,267 | $0 | $8.07M | 1.55% | +$8.07M |
| Protagonist Therapeutics Inc | 59,430 | 72,577 | +13,147 | $5.19M | $7.65M | 1.47% | +$2.46M |
| Tyra Biosciences, Inc.(TYRA) | 0 | 193,177 | +193,177 | $0 | $7.40M | 1.42% | +$7.40M |
| Dianthus Therapeutics, Inc.(DNTH) | 79,284 | 85,502 | +6,218 | $3.27M | $7.18M | 1.38% | +$3.91M |
| Celcuity Inc.(CELC) | 118,333 | 60,062 | -58,271 | $11.80M | $6.86M | 1.32% | -$4.95M |
| Definium Therapeutics, Inc.(DFTX) | 0 | 325,483 | +325,483 | $0 | $6.15M | 1.18% | +$6.15M |
| BioAge Labs, Inc.(BIOA) | 0 | 338,654 | +338,654 | $0 | $5.92M | 1.14% | +$5.92M |
| Newamsterdam Pharma Company ORDINARY SHARES | 73,106 | 180,658 | +107,552 | $2.56M | $5.78M | 1.11% | +$3.22M |
| Acadia Pharmaceuticals Inc | 0 | 242,566 | +242,566 | $0 | $5.40M | 1.04% | +$5.40M |
| Assembly Biosciences Inc | 156,728 | 185,435 | +28,707 | $5.33M | $5.15M | 0.99% | -$184.5K |
| Alumis Inc | 0 | 229,566 | +229,566 | $0 | $5.06M | 0.97% | +$5.06M |
| Nurix Therapeutics, Inc.(NRIX) | 0 | 315,226 | +315,226 | $0 | $4.89M | 0.94% | +$4.89M |
| Zura Bio LimitedCL A(ZURA) | 0 | 753,520 | +753,520 | $0 | $4.48M | 0.86% | +$4.48M |
| Evommune, Inc.(EVMN) | 68,196 | 193,777 | +125,581 | $1.17M | $4.39M | 0.84% | +$3.22M |
| Tango Therapeutics, Inc.(TNGX) | 0 | 200,919 | +200,919 | $0 | $4.20M | 0.81% | +$4.20M |
| Faeth Therapeutics, Inc.(FTH) | 0 | 132,873 | +132,873 | $0 | $4.19M | 0.81% | +$4.19M |
| Relmada Therapeutics, Inc.(RLMD) | 0 | 597,409 | +597,409 | $0 | $4.16M | 0.80% | +$4.16M |
| Erasca, Inc.(ERAS) | 0 | 239,861 | +239,861 | $0 | $3.88M | 0.75% | +$3.88M |
| Johnson & Johnson(JNJ) | 35,000 | 15,415 | -19,585 | $7.24M | $3.77M | 0.72% | -$3.48M |
| X4 Pharmaceuticals, Inc.(XFOR) | 898,465 | 850,742 | -47,723 | $3.59M | $3.51M | 0.68% | -$80.3K |
| Vaxcyte, Inc.(PCVX) | 0 | 59,061 | +59,061 | $0 | $3.43M | 0.66% | +$3.43M |
| Whitehawk Therapeutics, Inc.(WHWK) | 1,458,807 | 939,369 | -519,438 | $3.53M | $3.24M | 0.62% | -$289.5K |
| Helix Acquisition Corp. IIICL A(HLXC) | 0 | 305,028 | +305,028 | $0 | $3.10M | 0.60% | +$3.10M |
| Tenax Therapeutics, Inc.(TENX) | 0 | 188,700 | +188,700 | $0 | $3.02M | 0.58% | +$3.02M |
| Alkermes plcSHS(ALKS) | 0 | 80,492 | +80,492 | $0 | $2.85M | 0.55% | +$2.85M |
| Pharvaris N V COM | 58,389 | 86,637 | +28,248 | $1.62M | $2.45M | 0.47% | +$827.2K |
| Invivyd, Inc.(IVVD) | 989,822 | 1,874,546 | +884,724 | $2.44M | $2.44M | 0.47% | -$8.0K |
| Jade Biosciences Inc | 0 | 154,034 | +154,034 | $0 | $2.16M | 0.42% | +$2.16M |
| Twist Bioscience Corporation(TWST) | 518,355 | 43,110 | -475,245 | $16.44M | $2.05M | 0.39% | -$14.39M |
| MapLight Therapeutics, Inc.(MPLT) | 100,000 | 100,000 | 0 | $1.76M | $2.03M | 0.39% | +$276.5K |
| Avalo Therapeutics, Inc.(AVTX) | 135,552 | 134,742 | -810 | $2.46M | $2.01M | 0.39% | -$449.9K |
| Ionis Pharmaceuticals, Inc.(IONS) | 0 | 26,385 | +26,385 | $0 | $1.98M | 0.38% | +$1.98M |
| Immunocore Holdings plcADS(IMCR) | 0 | 63,543 | +63,543 | $0 | $1.92M | 0.37% | +$1.92M |
| Forte Biosciences Inc | 0 | 58,020 | +58,020 | $0 | $1.50M | 0.29% | +$1.50M |
| Sionna Therapeutics, Inc.(SION) | 0 | 36,540 | +36,540 | $0 | $1.46M | 0.28% | +$1.46M |
| SAB Biotherapeutics, Inc.(SABS) | 146,558 | 375,000 | +228,442 | $548.1K | $1.44M | 0.28% | +$888.1K |
| Solid Biosciences Inc | 0 | 195,403 | +195,403 | $0 | $1.41M | 0.27% | +$1.41M |
| Lipocine Inc.(LPCN) | 0 | 160,420 | +160,420 | $0 | $1.28M | 0.25% | +$1.28M |
| uniQure N.V.SHS(QURE) | 43,485 | 78,066 | +34,581 | $1.04M | $1.28M | 0.25% | +$235.8K |
| LB Pharmaceuticals Inc(LBRX) | 0 | 50,000 | +50,000 | $0 | $1.23M | 0.24% | +$1.23M |
| C4 Therapeutics, Inc.(CCCC) | 0 | 453,236 | +453,236 | $0 | $1.19M | 0.23% | +$1.19M |
| Edwards Lifesciences Corp | 0 | 14,588 | +14,588 | $0 | $1.17M | 0.22% | +$1.17M |
| Capricor Therapeutics, Inc.(CAPR) | 17,853 | 37,592 | +19,739 | $515.2K | $1.14M | 0.22% | +$627.6K |
| Biodesix, Inc.(BDSX) | 0 | 70,004 | +70,004 | $0 | $1.02M | 0.20% | +$1.02M |
| Sutro Biopharma, Inc.(STRO) | 0 | 23,295 | +23,295 | $0 | $580.3K | 0.11% | +$580.3K |
| Spruce Biosciences Inc | 0 | 6,360 | +6,360 | $0 | $415.6K | 0.08% | +$415.6K |
| Vistagen Therapeutics, Inc.(VTGN) | 616,749 | 616,749 | 0 | $142.1K | $58.2K | 0.01% | -$83.9K |
| AbbVie Inc.(ABBV) | 9,325 | 0 | -9,325 | $2.13M | $0 | — | -$2.13M |
| Adaptive Biotechnologies Corporation(ADPT) | 606,825 | 0 | -606,825 | $9.85M | $0 | — | -$9.85M |
| ADC Therapeutics SASHS(ADCT) | 502,570 | 0 | -502,570 | $1.77M | $0 | — | -$1.77M |
| Apogee Therapeutics Inc | 80,574 | 0 | -80,574 | $6.08M | $0 | — | -$6.08M |
| Arbutus Biopharma Corporation(ABUS) | 986,751 | 0 | -986,751 | $4.75M | $0 | — | -$4.75M |
| Arcellx Inc COMMON STOCK | 332,860 | 0 | -332,860 | $21.70M | $0 | — | -$21.70M |
| Ascendis Pharma A/SADR(ASND) | 14,842 | 0 | -14,842 | $3.16M | $0 | — | -$3.16M |
| Belite Bio, IncADS(BLTE) | 9,163 | 0 | -9,163 | $1.47M | $0 | — | -$1.47M |
| BridgeBio Oncology Therapeutics, Inc.(BBOT) | 86,517 | 0 | -86,517 | $1.08M | $0 | — | -$1.08M |
| Bright Minds Biosciences Inc.(DRUG) | 97,340 | 0 | -97,340 | $7.60M | $0 | — | -$7.60M |
| Centessa Pharmaceuticals PlcADS | 1,154,114 | 0 | -1,154,114 | $28.86M | $0 | — | -$28.86M |
| ClearPoint Neuro, Inc.(CLPT) | 481,858 | 0 | -481,858 | $6.59M | $0 | — | -$6.59M |
| CytomX Therapeutics, Inc.(CTMX) | 1,036,311 | 0 | -1,036,311 | $4.41M | $0 | — | -$4.41M |
| Eli Lilly and Company(LLY) | 4,759 | 0 | -4,759 | $5.11M | $0 | — | -$5.11M |
| IDEAYA Biosciences, Inc.(IDYA) | 161,659 | 0 | -161,659 | $5.59M | $0 | — | -$5.59M |
| Immatics N.V.SHS(IMTX) | 610,308 | 0 | -610,308 | $6.41M | $0 | — | -$6.41M |
| Incyte Corporation(INCY) | 61,435 | 0 | -61,435 | $6.07M | $0 | — | -$6.07M |
| Inventiva S.A.ADS(IVA) | 467,242 | 0 | -467,242 | $2.17M | $0 | — | -$2.17M |
| Legend Biotech CorporationADS(LEGN) | 73,328 | 0 | -73,328 | $1.59M | $0 | — | -$1.59M |
| Madrigal Pharmaceuticals, Inc.(MDGL) | 17,736 | 0 | -17,736 | $10.33M | $0 | — | -$10.33M |
| Maze Therapeutics, Inc.(MAZE) | 125,877 | 0 | -125,877 | $5.22M | $0 | — | -$5.22M |
| MeiraGTx Holdings plc(MGTX) | 287,689 | 0 | -287,689 | $2.29M | $0 | — | -$2.29M |
| Monte Rosa Therapeutics, Inc.(GLUE) | 61,577 | 0 | -61,577 | $965.5K | $0 | — | -$965.5K |
| MoonLake ImmunotherapeuticsCL A(MLTX) | 348,401 | 0 | -348,401 | $4.59M | $0 | — | -$4.59M |
| Nektar Therapeutics(NKTR) | 178,274 | 0 | -178,274 | $7.54M | $0 | — | -$7.54M |
| Ocular Therapeutix, Inc.(OCUL) | 522,693 | 0 | -522,693 | $6.35M | $0 | — | -$6.35M |
| Palisade Bio, Inc.(PALI) | 4,192,375 | 0 | -4,192,375 | $9.85M | $0 | — | -$9.85M |
| Pasithea Therapeutics Corp.(KTTA) | 355,082 | 0 | -355,082 | $458.1K | $0 | — | -$458.1K |
| IRulya Therapeutics Inc.(IRLA) | 739,264 | 0 | -739,264 | $2.48M | $0 | — | -$2.48M |
| Repligen Corporation(RGEN) | 15,707 | 0 | -15,707 | $2.57M | $0 | — | -$2.57M |