Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q3 2025 ▲▼ | Q4 2025 ▲▼ | Change ▲▼ | Q3 2025 ▲▼ | Q4 2025 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| ABIVAX Société AnonymeADS(ABVX) | 166,273 | 391,783 | +225,510 | $14.12M | $52.83M | 9.07% | +$38.72M |
| Scholar Rock Holding Corporation(SRRK) | 726,204 | 886,893 | +160,689 | $27.04M | $39.07M | 6.70% | +$12.02M |
| Centessa Pharmaceuticals PlcADS | 655,385 | 1,154,114 | +498,729 | $15.89M | $28.86M | 4.95% | +$12.97M |
| Syndax Pharmaceuticals, Inc.(SNDX) | 1,366,205 | 1,339,379 | -26,826 | $21.02M | $28.14M | 4.83% | +$7.12M |
| Structure Therapeutics IncADS | 129,335 | 351,073 | +221,738 | $3.62M | $24.42M | 4.19% | +$20.80M |
| Arcellx Inc COMMON STOCK | 11,376 | 332,860 | +321,484 | $934.0K | $21.70M | 3.72% | +$20.77M |
| Roivant Sciences Ltd.SHS(ROIV) | 4,197,187 | 966,698 | -3,230,489 | $63.50M | $20.98M | 3.60% | -$42.53M |
| Terns Pharmaceuticals Inc | 89,617 | 429,198 | +339,581 | $673.0K | $17.34M | 2.98% | +$16.67M |
| Twist Bioscience Corporation(TWST) | 0 | 518,355 | +518,355 | $0 | $16.44M | 2.82% | +$16.44M |
| Immunovant, Inc.(IMVT) | 1,589,580 | 644,959 | -944,621 | $25.62M | $16.39M | 2.81% | -$9.23M |
| Dyne Therapeutics, Inc.(DYN) | 474,612 | 835,200 | +360,588 | $6.00M | $16.34M | 2.80% | +$10.33M |
| Xenon Pharmaceuticals Inc.(XENE) | 192,295 | 348,605 | +156,310 | $7.72M | $15.62M | 2.68% | +$7.90M |
| Surrozen, Inc.(SRZN) | 713,463 | 619,766 | -93,697 | $9.19M | $12.67M | 2.17% | +$3.48M |
| Celcuity Inc.(CELC) | 136,710 | 118,333 | -18,377 | $6.75M | $11.80M | 2.03% | +$5.05M |
| Mineralys Therapeutics, Inc.(MLYS) | 158,112 | 290,049 | +131,937 | $6.00M | $10.53M | 1.81% | +$4.53M |
| Madrigal Pharmaceuticals, Inc.(MDGL) | 8,207 | 17,736 | +9,529 | $3.76M | $10.33M | 1.77% | +$6.56M |
| Adaptive Biotechnologies Corporation(ADPT) | 0 | 606,825 | +606,825 | $0 | $9.85M | 1.69% | +$9.85M |
| Palisade Bio, Inc.(PALI) | 0 | 4,192,375 | +4,192,375 | $0 | $9.85M | 1.69% | +$9.85M |
| Cytokinetics, Incorporated(CYTK) | 0 | 146,978 | +146,978 | $0 | $9.34M | 1.60% | +$9.34M |
| Edgewise Therapeutics, Inc.(EWTX) | 0 | 360,876 | +360,876 | $0 | $8.96M | 1.54% | +$8.96M |
| Bright Minds Biosciences Inc.(DRUG) | 0 | 97,340 | +97,340 | $0 | $7.60M | 1.30% | +$7.60M |
| Nektar Therapeutics(NKTR) | 53,201 | 178,274 | +125,073 | $3.03M | $7.54M | 1.29% | +$4.51M |
| Johnson & Johnson(JNJ) | 0 | 35,000 | +35,000 | $0 | $7.24M | 1.24% | +$7.24M |
| Denali Therapeutics Inc.(DNLI) | 1,734,659 | 419,058 | -1,315,601 | $25.19M | $6.92M | 1.19% | -$18.27M |
| Amylyx Pharmaceuticals, Inc.(AMLX) | 276,884 | 565,140 | +288,256 | $3.76M | $6.83M | 1.17% | +$3.06M |
| ClearPoint Neuro, Inc.(CLPT) | 16,651 | 481,858 | +465,207 | $362.8K | $6.59M | 1.13% | +$6.23M |
| Arcutis Biotherapeutics, Inc.(ARQT) | 411,893 | 224,740 | -187,153 | $7.76M | $6.53M | 1.12% | -$1.24M |
| EyePoint, Inc.(EYPT) | 0 | 353,849 | +353,849 | $0 | $6.46M | 1.11% | +$6.46M |
| Immatics N.V.SHS(IMTX) | 0 | 610,308 | +610,308 | $0 | $6.41M | 1.10% | +$6.41M |
| Ocular Therapeutix, Inc.(OCUL) | 359,470 | 522,693 | +163,223 | $4.20M | $6.35M | 1.09% | +$2.14M |
| Rhythm Pharmaceuticals, Inc.(RYTM) | 91,444 | 58,915 | -32,529 | $9.23M | $6.31M | 1.08% | -$2.93M |
| Praxis Precision Medicines, Inc.(PRAX) | 0 | 21,067 | +21,067 | $0 | $6.21M | 1.07% | +$6.21M |
| Apogee Therapeutics Inc | 0 | 80,574 | +80,574 | $0 | $6.08M | 1.04% | +$6.08M |
| Incyte Corporation(INCY) | 43,754 | 61,435 | +17,681 | $3.71M | $6.07M | 1.04% | +$2.36M |
| IDEAYA Biosciences, Inc.(IDYA) | 371,825 | 161,659 | -210,166 | $10.12M | $5.59M | 0.96% | -$4.53M |
| Assembly Biosciences Inc | 66,130 | 156,728 | +90,598 | $1.69M | $5.33M | 0.91% | +$3.64M |
| Maze Therapeutics, Inc.(MAZE) | 0 | 125,877 | +125,877 | $0 | $5.22M | 0.89% | +$5.22M |
| Protagonist Therapeutics Inc | 47,954 | 59,430 | +11,476 | $3.19M | $5.19M | 0.89% | +$2.01M |
| Eli Lilly and Company(LLY) | 0 | 4,759 | +4,759 | $0 | $5.11M | 0.88% | +$5.11M |
| Trevi Therapeutics, Inc.(TRVI) | 350,710 | 399,557 | +48,847 | $3.21M | $5.00M | 0.86% | +$1.79M |
| Revolution Medicines, Inc.(RVMD) | 185,380 | 62,032 | -123,348 | $8.66M | $4.94M | 0.85% | -$3.72M |
| Viridian Therapeutics, Inc.(VRDN) | 0 | 154,320 | +154,320 | $0 | $4.80M | 0.82% | +$4.80M |
| Arbutus Biopharma Corporation(ABUS) | 205,388 | 986,751 | +781,363 | $932.5K | $4.75M | 0.81% | +$3.81M |
| MoonLake ImmunotherapeuticsCL A(MLTX) | 0 | 348,401 | +348,401 | $0 | $4.59M | 0.79% | +$4.59M |
| CytomX Therapeutics, Inc.(CTMX) | 0 | 1,036,311 | +1,036,311 | $0 | $4.41M | 0.76% | +$4.41M |
| X4 Pharmaceuticals, Inc.(XFOR) | 555,411 | 898,465 | +343,054 | $1.90M | $3.59M | 0.62% | +$1.69M |
| Whitehawk Therapeutics, Inc.(WHWK) | 424,082 | 1,458,807 | +1,034,725 | $805.8K | $3.53M | 0.61% | +$2.72M |
| Dianthus Therapeutics, Inc.(DNTH) | 41,382 | 79,284 | +37,902 | $1.63M | $3.27M | 0.56% | +$1.64M |
| Ascendis Pharma A/SADR(ASND) | 15,149 | 14,842 | -307 | $3.01M | $3.16M | 0.54% | +$153.1K |
| Repligen Corporation(RGEN) | 0 | 15,707 | +15,707 | $0 | $2.57M | 0.44% | +$2.57M |
| Newamsterdam Pharma Company ORDINARY SHARES | 150,573 | 73,106 | -77,467 | $4.28M | $2.56M | 0.44% | -$1.72M |
| MBX Biosciences, Inc.(MBX) | 75,000 | 78,553 | +3,553 | $1.31M | $2.48M | 0.43% | +$1.17M |
| IRulya Therapeutics Inc.(IRLA) | 0 | 739,264 | +739,264 | $0 | $2.48M | 0.43% | +$2.48M |
| Avalo Therapeutics, Inc.(AVTX) | 0 | 135,552 | +135,552 | $0 | $2.46M | 0.42% | +$2.46M |
| Invivyd, Inc.(IVVD) | 278,608 | 989,822 | +711,214 | $306.5K | $2.44M | 0.42% | +$2.14M |
| MeiraGTx Holdings plc(MGTX) | 81,858 | 287,689 | +205,831 | $673.7K | $2.29M | 0.39% | +$1.61M |
| Inventiva S.A.ADS(IVA) | 30,824 | 467,242 | +436,418 | $178.5K | $2.17M | 0.37% | +$1.99M |
| AbbVie Inc.(ABBV) | 0 | 9,325 | +9,325 | $0 | $2.13M | 0.37% | +$2.13M |
| ADC Therapeutics SASHS(ADCT) | 283,286 | 502,570 | +219,284 | $1.13M | $1.77M | 0.30% | +$640.9K |
| MapLight Therapeutics, Inc.(MPLT) | 0 | 100,000 | +100,000 | $0 | $1.76M | 0.30% | +$1.76M |
| Pharvaris N V COM | 0 | 58,389 | +58,389 | $0 | $1.62M | 0.28% | +$1.62M |
| Legend Biotech CorporationADS(LEGN) | 0 | 73,328 | +73,328 | $0 | $1.59M | 0.27% | +$1.59M |
| Belite Bio, IncADS(BLTE) | 0 | 9,163 | +9,163 | $0 | $1.47M | 0.25% | +$1.47M |
| Xilio Therapeutics, Inc.(XLO) | 0 | 2,030,028 | +2,030,028 | $0 | $1.30M | 0.22% | +$1.30M |
| Evommune, Inc.(EVMN) | 0 | 68,196 | +68,196 | $0 | $1.17M | 0.20% | +$1.17M |
| BridgeBio Oncology Therapeutics, Inc.(BBOT) | 186,614 | 86,517 | -100,097 | $2.16M | $1.08M | 0.19% | -$1.08M |
| Spyre Therapeutics, Inc.(SYRE) | 0 | 32,377 | +32,377 | $0 | $1.06M | 0.18% | +$1.06M |
| uniQure N.V.SHS(QURE) | 522,155 | 43,485 | -478,670 | $30.48M | $1.04M | 0.18% | -$29.44M |
| Taysha Gene Therapies, Inc.(TSHA) | 839,669 | 182,130 | -657,539 | $2.75M | $1.00M | 0.17% | -$1.74M |
| Monte Rosa Therapeutics, Inc.(GLUE) | 0 | 61,577 | +61,577 | $0 | $965.5K | 0.17% | +$965.5K |
| SAB Biotherapeutics, Inc.(SABS) | 0 | 146,558 | +146,558 | $0 | $548.1K | 0.09% | +$548.1K |
| Vanda Pharmaceuticals Inc.(VNDA) | 0 | 58,989 | +58,989 | $0 | $520.3K | 0.09% | +$520.3K |
| Capricor Therapeutics, Inc.(CAPR) | 0 | 17,853 | +17,853 | $0 | $515.2K | 0.09% | +$515.2K |
| Pasithea Therapeutics Corp.(KTTA) | 0 | 355,082 | +355,082 | $0 | $458.1K | 0.08% | +$458.1K |
| Vistagen Therapeutics, Inc.(VTGN) | 2,488,685 | 616,749 | -1,871,936 | $7.75M | $142.1K | 0.02% | -$7.61M |
| Akero Therapeutics Inc | 121,410 | 0 | -121,410 | $5.76M | $0 | — | -$5.76M |
| Alkermes plcSHS(ALKS) | 241,637 | 0 | -241,637 | $7.25M | $0 | — | -$7.25M |
| Arcturus Therapeutics Holdings Inc.(ARCT) | 35,606 | 0 | -35,606 | $656.2K | $0 | — | -$656.2K |
| argenx SEADR(ARGX) | 12,465 | 0 | -12,465 | $9.19M | $0 | — | -$9.19M |
| Atai Life Sciences NvSHS | 76,032 | 0 | -76,032 | $402.2K | $0 | — | -$402.2K |
| Avidity Biosciences Inc | 114,053 | 0 | -114,053 | $4.97M | $0 | — | -$4.97M |
| Biohaven Ltd.(BHVN) | 1,017,311 | 0 | -1,017,311 | $15.27M | $0 | — | -$15.27M |
| BridgeBio Pharma, Inc.(BBIO) | 127,435 | 0 | -127,435 | $6.62M | $0 | — | -$6.62M |
| CG Oncology, Inc.(CGON) | 63,019 | 0 | -63,019 | $2.54M | $0 | — | -$2.54M |
| Cidara Therapeutics Inc | 152,325 | 0 | -152,325 | $14.59M | $0 | — | -$14.59M |
| COMPASS Pathways plcADS(CMPS) | 275,620 | 0 | -275,620 | $1.58M | $0 | — | -$1.58M |
| Corvus Pharmaceuticals, Inc.(CRVS) | 96,439 | 0 | -96,439 | $710.8K | $0 | — | -$710.8K |
| Enanta Pharmaceuticals, Inc.(ENTA) | 75,194 | 0 | -75,194 | $900.1K | $0 | — | -$900.1K |
| Equillium, Inc.(EQ) | 1,908,935 | 0 | -1,908,935 | $2.73M | $0 | — | -$2.73M |
| GH Research PLC(GHRS) | 545,275 | 0 | -545,275 | $7.80M | $0 | — | -$7.80M |
| Harrow, Inc.(HROW) | 57,619 | 0 | -57,619 | $2.78M | $0 | — | -$2.78M |
| Insmed Incorporated(INSM) | 43,419 | 0 | -43,419 | $6.25M | $0 | — | -$6.25M |
| Invesco Qqq TrUNIT SER 1 | 3,797 | 0 | -3,797 | $2.28M | $0 | — | -$2.28M |
| Jazz Pharmaceuticals plcSHS USD(JAZZ) | 39,072 | 0 | -39,072 | $5.15M | $0 | — | -$5.15M |
| Kalvista Pharmaceuticals Inc | 56,770 | 0 | -56,770 | $691.5K | $0 | — | -$691.5K |
| Mind Medicine Mindmed Inc | 76,875 | 0 | -76,875 | $906.4K | $0 | — | -$906.4K |
| ORIC Pharmaceuticals, Inc.(ORIC) | 166,461 | 0 | -166,461 | $2.00M | $0 | — | -$2.00M |
| PepGen Inc.(PEPG) | 389,189 | 0 | -389,189 | $1.80M | $0 | — | -$1.80M |
| Perceptive Cap Solutions CorCL A CL A ORD SHS | 150,000 | 0 | -150,000 | $1.59M | $0 | — | -$1.59M |
| Protara Therapeutics, Inc.(TARA) | 363,666 | 0 | -363,666 | $1.58M | $0 | — | -$1.58M |