Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q4 2023 ▲▼ | Q1 2024 ▲▼ | Change ▲▼ | Q4 2023 ▲▼ | Q1 2024 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| Cytokinetics, Incorporated(CYTK) | 50,000 | 2,150,000 | +2,100,000 | $4.17M | $150.74M | 12.47% | +$146.56M |
| Jazz Pharmaceuticals plcSHS USD(JAZZ) | 725,000 | 1,100,000 | +375,000 | $89.17M | $132.46M | 10.95% | +$43.29M |
| Neurocrine Biosciences, Inc.(NBIX) | 800,000 | 710,000 | -90,000 | $105.41M | $97.92M | 8.10% | -$7.48M |
| Ascendis Pharma A/SADR(ASND) | 625,000 | 525,000 | -100,000 | $78.72M | $79.36M | 6.56% | +$645.5K |
| Globus Medical, Inc.CL A(GMED) | 800,000 | 1,000,000 | +200,000 | $42.63M | $53.64M | 4.44% | +$11.01M |
| Soleno Therapeutics Inc | 1,300,000 | 1,250,000 | -50,000 | $52.33M | $53.50M | 4.42% | +$1.18M |
| Alnylam Pharmaceuticals, Inc.(ALNY) | 35,000 | 350,000 | +315,000 | $6.70M | $52.31M | 4.33% | +$45.61M |
| BeOne Medicines AGADR(ONC) | 0 | 325,000 | +325,000 | $0 | $50.83M | 4.20% | +$50.83M |
| Inari Medical Inc | 0 | 800,000 | +800,000 | $0 | $38.38M | 3.17% | +$38.38M |
| Applied Therapeutics Inc | 4,155,000 | 5,110,000 | +955,000 | $13.92M | $34.75M | 2.87% | +$20.83M |
| Liquidia Corporation(LQDA) | 1,025,000 | 2,000,000 | +975,000 | $12.33M | $29.50M | 2.44% | +$17.17M |
| ALX Oncology Holdings Inc.(ALXO) | 1,655,000 | 2,610,000 | +955,000 | $24.64M | $29.10M | 2.41% | +$4.46M |
| AstraZeneca PLCADR(AZN) | 250,000 | 400,000 | +150,000 | $16.84M | $27.10M | 2.24% | +$10.26M |
| uniQure N.V.SHS(QURE) | 3,925,000 | 4,725,000 | +800,000 | $26.57M | $24.57M | 2.03% | -$2.00M |
| Insmed Incorporated(INSM) | 900,000 | 750,000 | -150,000 | $27.89M | $20.35M | 1.68% | -$7.54M |
| argenx SEADR(ARGX) | 0 | 50,000 | +50,000 | $0 | $19.69M | 1.63% | +$19.69M |
| Xenon Pharmaceuticals Inc.(XENE) | 175,000 | 400,000 | +225,000 | $8.06M | $17.22M | 1.42% | +$9.16M |
| TG Therapeutics, Inc.(TGTX) | 0 | 1,050,000 | +1,050,000 | $0 | $15.97M | 1.32% | +$15.97M |
| Astria Therapeutics Inc | 0 | 1,100,000 | +1,100,000 | $0 | $15.48M | 1.28% | +$15.48M |
| BioMarin Pharmaceutical Inc.(BMRN) | 0 | 175,000 | +175,000 | $0 | $15.28M | 1.26% | +$15.28M |
| Alpine Immune Sciences Inc | 0 | 350,000 | +350,000 | $0 | $13.87M | 1.15% | +$13.87M |
| Solid Biosciences Inc | 34,085 | 1,035,000 | +1,000,915 | $209.3K | $13.79M | 1.14% | +$13.58M |
| Dianthus Therapeutics, Inc.(DNTH) | 135,000 | 455,000 | +320,000 | $1.40M | $13.65M | 1.13% | +$12.25M |
| Apellis Pharmaceuticals Inc COM | 0 | 225,000 | +225,000 | $0 | $13.23M | 1.09% | +$13.23M |
| Sarepta Therapeutics, Inc.(SRPT) | 0 | 100,000 | +100,000 | $0 | $12.95M | 1.07% | +$12.95M |
| Praxis Precision Medicines, Inc.(PRAX) | 0 | 210,000 | +210,000 | $0 | $12.81M | 1.06% | +$12.81M |
| Immatics N.V.SHS(IMTX) | 2,100,000 | 1,200,000 | -900,000 | $22.11M | $12.61M | 1.04% | -$9.50M |
| Incyte Corporation(INCY) | 0 | 200,000 | +200,000 | $0 | $11.39M | 0.94% | +$11.39M |
| MacroGenics, Inc.(MGNX) | 0 | 725,000 | +725,000 | $0 | $10.67M | 0.88% | +$10.67M |
| Agios Pharmaceuticals, Inc.(AGIO) | 0 | 325,000 | +325,000 | $0 | $9.50M | 0.79% | +$9.50M |
| Shockwave Medical Inc | 0 | 25,000 | +25,000 | $0 | $8.14M | 0.67% | +$8.14M |
| Krystal Biotech, Inc.(KRYS) | 0 | 45,000 | +45,000 | $0 | $8.01M | 0.66% | +$8.01M |
| KalVista Pharmaceuticals Inc | 0 | 655,000 | +655,000 | $0 | $7.77M | 0.64% | +$7.77M |
| Geron Corporation(GERN) | 0 | 2,200,000 | +2,200,000 | $0 | $7.26M | 0.60% | +$7.26M |
| Arcellx Inc COMMON STOCK | 60,000 | 100,000 | +40,000 | $3.33M | $6.96M | 0.58% | +$3.63M |
| Endeavour Silver Corp.(EXK) | 0 | 100,000 | +100,000 | $0 | $6.91M | 0.57% | +$6.91M |
| Fulcrum Therapeutics, Inc.(FULC) | 1,025,000 | 695,000 | -330,000 | $6.92M | $6.56M | 0.54% | -$357.9K |
| Viking Therapeutics, Inc.(VKTX) | 0 | 75,000 | +75,000 | $0 | $6.15M | 0.51% | +$6.15M |
| Passage Bio, Inc.(PASG) | 0 | 4,500,000 | +4,500,000 | $0 | $6.08M | 0.50% | +$6.08M |
| Allogene Therapeutics Inc | 0 | 1,350,000 | +1,350,000 | $0 | $6.03M | 0.50% | +$6.03M |
| Fate Therapeutics, Inc.(FATE) | 1,290,000 | 800,000 | -490,000 | $4.82M | $5.87M | 0.49% | +$1.05M |
| Voyager Therapeutics, Inc.(VYGR) | 0 | 600,000 | +600,000 | $0 | $5.59M | 0.46% | +$5.59M |
| Relmada Therapeutics, Inc.(RLMD) | 115,000 | 1,200,000 | +1,085,000 | $476.1K | $5.58M | 0.46% | +$5.10M |
| Bio-Rad Laboratories IncCL A | 0 | 15,000 | +15,000 | $0 | $5.19M | 0.43% | +$5.19M |
| Ultragenyx Pharmaceutical Inc.(RARE) | 0 | 110,000 | +110,000 | $0 | $5.14M | 0.42% | +$5.14M |
| Lyra Therapeutics Inc | 3,000,000 | 800,000 | -2,200,000 | $15.72M | $4.98M | 0.41% | -$10.74M |
| Lakefront Biotherapeutics NVADR(LKFT) | 130,000 | 130,000 | 0 | $5.28M | $4.19M | 0.35% | -$1.10M |
| Alto Neuroscience, Inc.(ANRO) | 0 | 250,000 | +250,000 | $0 | $3.84M | 0.32% | +$3.84M |
| Lexeo Therapeutics, Inc.(LXEO) | 0 | 175,000 | +175,000 | $0 | $2.74M | 0.23% | +$2.74M |
| Prime Medicine, Inc.(PRME) | 20,306 | 360,000 | +339,694 | $179.9K | $2.52M | 0.21% | +$2.34M |
| Novavax, Inc.(NVAX) | 0 | 500,000 | +500,000 | $0 | $2.39M | 0.20% | +$2.39M |
| Pacira BioSciences, Inc.(PCRX) | 1,200,000 | 80,000 | -1,120,000 | $40.49M | $2.34M | 0.19% | -$38.15M |
| Atara Biotherapeutics Inc | 0 | 2,800,000 | +2,800,000 | $0 | $1.94M | 0.16% | +$1.94M |
| Achilles Therapeutics PLCADS | 108,083 | 1,500,000 | +1,391,917 | $96.1K | $1.88M | 0.16% | +$1.78M |
| Chimerix Inc | 1,400,000 | 1,400,000 | 0 | $1.35M | $1.48M | 0.12% | +$136.5K |
| Reneo Pharmaceuticals Inc | 400,000 | 295,375 | -104,625 | $640.0K | $490.3K | 0.04% | -$149.7K |
| Affimed NV | 0 | 55,000 | +55,000 | $0 | $291.5K | 0.02% | +$291.5K |
| Lyell Immunopharma, Inc.(LYEL) | 0 | 130,000 | +130,000 | $0 | $289.9K | 0.02% | +$289.9K |
| Aerovate Therapeutics Inc | 400,000 | 0 | -400,000 | $9.05M | $0 | — | -$9.05M |
| Affimed NV | 546,067 | 0 | -546,067 | $341.3K | $0 | — | -$341.3K |
| Arcutis Biotherapeutics, Inc.(ARQT) | 2,700,000 | 0 | -2,700,000 | $8.72M | $0 | — | -$8.72M |
| Biogen Inc.(BIIB) | 75,000 | 0 | -75,000 | $19.41M | $0 | — | -$19.41M |
| Bluebird Bio Inc | 2,150,000 | 0 | -2,150,000 | $2.97M | $0 | — | -$2.97M |
| Crinetics Pharmaceuticals Inc | 450,000 | 0 | -450,000 | $16.01M | $0 | — | -$16.01M |
| Cymabay Therapeutics Inc | 1,625,000 | 0 | -1,625,000 | $38.38M | $0 | — | -$38.38M |
| Edwards Lifesciences Corp | 225,000 | 0 | -225,000 | $17.16M | $0 | — | -$17.16M |
| Ikena Oncology Inc | 322,671 | 0 | -322,671 | $635.7K | $0 | — | -$635.7K |
| Inhibrx Inc | 1,530,000 | 0 | -1,530,000 | $58.14M | $0 | — | -$58.14M |
| Merck & Co., Inc.(MRK) | 400,000 | 0 | -400,000 | $43.61M | $0 | — | -$43.61M |
| Nuvalent Inc | 200,000 | 0 | -200,000 | $14.72M | $0 | — | -$14.72M |
| Ovid Therapeutics Inc.(OVID) | 85,429 | 0 | -85,429 | $275.1K | $0 | — | -$275.1K |
| Pyxis Oncology, Inc.(PYXS) | 440,000 | 0 | -440,000 | $792.0K | $0 | — | -$792.0K |
| Regeneron Pharmaceuticals, Inc.(REGN) | 10,000 | 0 | -10,000 | $8.78M | $0 | — | -$8.78M |
| Revolution Medicines, Inc.(RVMD) | 725,000 | 0 | -725,000 | $20.79M | $0 | — | -$20.79M |
| SanofiADR(SNY) | 300,000 | 0 | -300,000 | $14.92M | $0 | — | -$14.92M |
| Teva Pharmaceutical Industries LimitedADS(TEVA) | 200,000 | 0 | -200,000 | $2.09M | $0 | — | -$2.09M |
| Vaxcyte, Inc.(PCVX) | 525,000 | 0 | -525,000 | $32.97M | $0 | — | -$32.97M |
| Viridian Therapeutics, Inc.(VRDN) | 1,000,000 | 0 | -1,000,000 | $21.78M | $0 | — | -$21.78M |