Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q1 2026 ▲▼ | Q2 2026 ▲▼ | Change ▲▼ | Q1 2026 ▲▼ | Q2 2026 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| BioMarin Pharmaceutical Inc.(BMRN) | 3,575,000 | 6,025,000 | +2,450,000 | $201.95M | $344.75M | 8.06% | +$142.80M |
| Neurocrine Biosciences, Inc.(NBIX) | 1,250,000 | 1,880,000 | +630,000 | $164.68M | $316.85M | 7.40% | +$152.17M |
| ABIVAX Société Anonyme(ABVX) | 1,500,000 | 2,349,443 | +849,443 | $167.03M | $313.09M | 7.32% | +$146.06M |
| United Therapeutics Corporation(UTHR) | 75,000 | 435,000 | +360,000 | $44.47M | $235.70M | 5.51% | +$191.22M |
| Enliven Therapeutics Inc | 3,250,000 | 4,000,000 | +750,000 | $127.40M | $203.00M | 4.74% | +$75.60M |
| Nurix Therapeutics, Inc.(NRIX) | 6,500,000 | 8,050,000 | +1,550,000 | $100.75M | $195.29M | 4.56% | +$94.54M |
| Bicara Therapeutics Inc | 5,425,000 | 5,250,000 | -175,000 | $107.90M | $155.87M | 3.64% | +$47.97M |
| Taysha Gene Therapies, Inc.(TSHA) | 18,000,000 | 19,415,000 | +1,415,000 | $80.46M | $132.22M | 3.09% | +$51.76M |
| Arrowhead Pharmaceuticals, Inc.(ARWR) | 2,275,000 | 1,575,000 | -700,000 | $142.64M | $128.38M | 3.00% | -$14.26M |
| Abbott Laboratories | 0 | 1,400,000 | +1,400,000 | $0 | $127.04M | 2.97% | +$127.04M |
| Zimmer Biomet Holdings, Inc.(ZBH) | 190,000 | 1,400,000 | +1,210,000 | $17.18M | $120.53M | 2.82% | +$103.35M |
| Disc Medicine, Inc.(IRON) | 700,000 | 1,550,000 | +850,000 | $44.76M | $113.37M | 2.65% | +$68.61M |
| Monte Rosa Therapeutics, Inc.(GLUE) | 3,603,465 | 4,600,000 | +996,535 | $59.28M | $111.32M | 2.60% | +$52.04M |
| Insulet Corporation(PODD) | 50,601 | 670,000 | +619,399 | $10.62M | $102.01M | 2.38% | +$91.39M |
| Ascendis Pharma A/S(ASND) | 0 | 375,000 | +375,000 | $0 | $100.02M | 2.34% | +$100.02M |
| AstraZeneca PLC(AZN) | 100,000 | 450,000 | +350,000 | $19.72M | $85.33M | 1.99% | +$65.61M |
| Sanofi(SNY) | 1,400,000 | 2,000,000 | +600,000 | $67.45M | $85.32M | 1.99% | +$17.87M |
| Revolution Medicines, Inc.(RVMD) | 2,375,000 | 450,000 | -1,925,000 | $230.97M | $84.28M | 1.97% | -$146.69M |
| BioCryst Pharmaceuticals, Inc.(BCRX) | 7,025,000 | 8,300,000 | +1,275,000 | $66.88M | $83.00M | 1.94% | +$16.12M |
| Dyne Therapeutics, Inc.(DYN) | 4,000,000 | 3,375,000 | -625,000 | $72.52M | $74.96M | 1.75% | +$2.44M |
| Nektar Therapeutics(NKTR) | 285,000 | 1,000,000 | +715,000 | $20.51M | $69.81M | 1.63% | +$49.30M |
| Globus Medical, Inc.(GMED) | 610,520 | 850,000 | +239,480 | $52.60M | $67.16M | 1.57% | +$14.56M |
| Tarsus Pharmaceuticals, Inc.(TARS) | 200,000 | 1,050,000 | +850,000 | $14.03M | $66.09M | 1.54% | +$52.06M |
| Immatics N.V.(IMTX) | 6,175,000 | 6,175,000 | 0 | $60.76M | $62.55M | 1.46% | +$1.79M |
| Trevi Therapeutics, Inc.(TRVI) | 2,166,504 | 3,100,000 | +933,496 | $25.85M | $57.81M | 1.35% | +$31.97M |
| Immunocore Holdings plc(IMCR) | 2,766,868 | 1,800,000 | -966,868 | $83.42M | $57.15M | 1.34% | -$26.27M |
| Repligen Corporation(RGEN) | 925,000 | 400,000 | -525,000 | $108.98M | $54.58M | 1.28% | -$54.41M |
| Bristol-Myers Squibb Company(BMY) | 1,000,000 | 800,000 | -200,000 | $60.65M | $46.10M | 1.08% | -$14.55M |
| uniQure N.V.(QURE) | 358,996 | 935,000 | +576,004 | $5.87M | $43.07M | 1.01% | +$37.20M |
| Xenon Pharmaceuticals Inc.(XENE) | 639,900 | 700,000 | +60,100 | $37.21M | $42.25M | 0.99% | +$5.04M |
| Bright Minds Biosciences Inc | 492,319 | 545,000 | +52,681 | $35.92M | $38.26M | 0.89% | +$2.33M |
| Madrigal Pharmaceuticals, Inc.(MDGL) | 31,468 | 65,000 | +33,532 | $16.47M | $34.90M | 0.82% | +$18.43M |
| Alcon Inc.(ALC) | 800,000 | 500,000 | -300,000 | $60.28M | $33.55M | 0.78% | -$26.73M |
| Myriad Genetics Inc | 1,648,000 | 5,735,000 | +4,087,000 | $7.42M | $32.75M | 0.77% | +$25.33M |
| Rapport Therapeutics, Inc.(RAPP) | 1,436,229 | 730,000 | -706,229 | $44.94M | $30.42M | 0.71% | -$14.52M |
| Crescent Biopharma Inc | 1,500,000 | 1,630,000 | +130,000 | $27.55M | $29.34M | 0.69% | +$1.78M |
| GE HealthCare Technologies Inc.(GEHC) | 250,000 | 450,000 | +200,000 | $17.80M | $28.80M | 0.67% | +$11.01M |
| Insmed Incorporated(INSM) | 0 | 250,000 | +250,000 | $0 | $26.66M | 0.62% | +$26.66M |
| Viking Therapeutics, Inc.(VKTX) | 914,147 | 680,000 | -234,147 | $29.75M | $26.53M | 0.62% | -$3.22M |
| Beta Bionics, Inc.(BBNX) | 2,211,518 | 1,600,000 | -611,518 | $22.16M | $25.07M | 0.59% | +$2.91M |
| Regeneron Pharmaceuticals, Inc.(REGN) | 40,000 | 40,000 | 0 | $30.91M | $24.94M | 0.58% | -$5.96M |
| Solid Biosciences Inc | 5,000,000 | 2,160,000 | -2,840,000 | $36.00M | $21.58M | 0.50% | -$14.42M |
| Alto Neuroscience, Inc.(ANRO) | 2,064,075 | 785,000 | -1,279,075 | $46.40M | $20.72M | 0.48% | -$25.68M |
| First Tracks Biotherapeutics I | 0 | 1,013,000 | +1,013,000 | $0 | $20.38M | 0.48% | +$20.38M |
| Lexeo Therapeutics Inc | 4,475,000 | 4,320,000 | -155,000 | $25.69M | $20.11M | 0.47% | -$5.58M |
| Savara Inc.(SVRA) | 2,600,052 | 2,720,000 | +119,948 | $14.20M | $16.76M | 0.39% | +$2.56M |
| Damora Therapeutics, Inc.(DMRA) | 600,000 | 575,000 | -25,000 | $15.54M | $14.96M | 0.35% | -$584.3K |
| SpyGlass Pharma, Inc.(SGP) | 666,760 | 670,000 | +3,240 | $17.28M | $14.91M | 0.35% | -$2.36M |
| Tectonic Therapeutic Inc | 328,000 | 425,000 | +97,000 | $10.14M | $14.61M | 0.34% | +$4.47M |
| Avalo Therapeutics Inc | 0 | 775,000 | +775,000 | $0 | $14.32M | 0.33% | +$14.32M |
| Evommune Inc | 0 | 1,000,000 | +1,000,000 | $0 | $13.29M | 0.31% | +$13.29M |
| Kailera Therapeutics Inc | 0 | 575,000 | +575,000 | $0 | $12.67M | 0.30% | +$12.67M |
| Anteris Technologies Global Co | 1,144,780 | 1,010,000 | -134,780 | $6.35M | $9.95M | 0.23% | +$3.59M |
| Zenas BioPharma, Inc.(ZBIO) | 200,000 | 365,000 | +165,000 | $3.91M | $9.26M | 0.22% | +$5.35M |
| Voyager Therapeutics Inc | 3,002,936 | 2,625,000 | -377,936 | $11.59M | $9.19M | 0.21% | -$2.40M |
| OnKure Therapeutics Inc | 1,839,819 | 1,825,699 | -14,120 | $7.62M | $8.33M | 0.19% | +$708.3K |
| Surrozen Inc | 338,611 | 304,669 | -33,942 | $9.86M | $7.91M | 0.18% | -$1.96M |
| Monopar Therapeutics Inc | 65,418 | 75,727 | +10,309 | $3.58M | $7.01M | 0.16% | +$3.43M |
| Zura Bio Ltd | 511,000 | 1,173,956 | +662,956 | $3.04M | $6.93M | 0.16% | +$3.89M |
| Olema Pharmaceuticals Inc | 428,551 | 418,551 | -10,000 | $6.39M | $5.24M | 0.12% | -$1.15M |
| Palisade Bio Inc | 2,500,000 | 2,500,000 | 0 | $4.38M | $5.22M | 0.12% | +$850.0K |
| iBio Inc | 0 | 2,600,000 | +2,600,000 | $0 | $4.55M | 0.11% | +$4.55M |
| Sagimet Biosciences Inc | 0 | 535,452 | +535,452 | $0 | $4.14M | 0.10% | +$4.14M |
| enGene Therapeutics Inc | 0 | 1,667,430 | +1,667,430 | $0 | $2.88M | 0.07% | +$2.88M |
| Rezolute Inc | 0 | 382,999 | +382,999 | $0 | $1.99M | 0.05% | +$1.99M |
| Nyxoah SA SHS | 868,661 | 843,461 | -25,200 | $2.54M | $1.43M | 0.03% | -$1.11M |
| Tenax Therapeutics Inc | 53,439 | 53,439 | 0 | $854.5K | $777.5K | 0.02% | -$77.0K |
| Aprea Therapeutics Inc | 350,000 | 350,000 | 0 | $267.0K | $280.8K | 0.01% | +$13.8K |
| Absci Corp | 232,219 | 0 | -232,219 | $696.7K | $0 | — | -$696.7K |
| Agios Pharmaceuticals, Inc.(AGIO) | 450,000 | 0 | -450,000 | $15.22M | $0 | — | -$15.22M |
| Apogee Therapeutics Inc | 1,100,000 | 0 | -1,100,000 | $92.59M | $0 | — | -$92.59M |
| Arvinas Inc | 905,465 | 0 | -905,465 | $9.60M | $0 | — | -$9.60M |
| Ascendis Pharma A/S(ASND) | 375,000 | 0 | -375,000 | $85.77M | $0 | — | -$85.77M |
| Boston Scientific Corporation(BSX) | 800,000 | 0 | -800,000 | $50.20M | $0 | — | -$50.20M |
| Candel Therapeutics Inc | 1,125,000 | 0 | -1,125,000 | $5.51M | $0 | — | -$5.51M |
| Celldex Therapeutics, Inc.(CLDX) | 1,224,165 | 0 | -1,224,165 | $38.83M | $0 | — | -$38.83M |
| Cogent Biosciences, Inc.(COGT) | 1,230,888 | 0 | -1,230,888 | $47.38M | $0 | — | -$47.38M |
| Cytokinetics, Incorporated(CYTK) | 300,000 | 0 | -300,000 | $19.77M | $0 | — | -$19.77M |
| Denali Therapeutics Inc.(DNLI) | 1,773,326 | 0 | -1,773,326 | $34.05M | $0 | — | -$34.05M |
| enGene Therapeutics Inc COM | 2,165,000 | 0 | -2,165,000 | $14.74M | $0 | — | -$14.74M |
| Fulcrum Therapeutics Inc | 1,100,000 | 0 | -1,100,000 | $8.44M | $0 | — | -$8.44M |
| GeneDx Holdings Corp.(WGS) | 250,000 | 0 | -250,000 | $16.05M | $0 | — | -$16.05M |
| Geron Corp | 2,540,000 | 0 | -2,540,000 | $3.78M | $0 | — | -$3.78M |
| Inspire Medical Systems, Inc.(INSP) | 539,269 | 0 | -539,269 | $27.82M | $0 | — | -$27.82M |
| KalVista Pharmaceuticals Inc | 1,850,000 | 0 | -1,850,000 | $37.24M | $0 | — | -$37.24M |
| MacroGenics Inc | 280,000 | 0 | -280,000 | $809.2K | $0 | — | -$809.2K |
| MapLight Therapeutics Inc | 420,000 | 0 | -420,000 | $8.54M | $0 | — | -$8.54M |
| NovoCure Limited(NVCR) | 250,000 | 0 | -250,000 | $2.73M | $0 | — | -$2.73M |
| Nuvalent Inc | 481,715 | 0 | -481,715 | $49.35M | $0 | — | -$49.35M |
| Passage Bio Inc | 305,000 | 0 | -305,000 | $2.39M | $0 | — | -$2.39M |
| Protagonist Therapeutics Inc | 326,159 | 0 | -326,159 | $34.38M | $0 | — | -$34.38M |
| REGENXBIO Inc | 108,525 | 0 | -108,525 | $909.4K | $0 | — | -$909.4K |
| Scholar Rock Holding Corporation(SRRK) | 1,324,422 | 0 | -1,324,422 | $65.11M | $0 | — | -$65.11M |
| Soleno Therapeutics Inc | 730,000 | 0 | -730,000 | $24.44M | $0 | — | -$24.44M |
| Terns Pharmaceuticals Inc | 1,000,000 | 0 | -1,000,000 | $52.72M | $0 | — | -$52.72M |
| Tyra Biosciences, Inc.(TYRA) | 54,000 | 0 | -54,000 | $2.07M | $0 | — | -$2.07M |
| UroGen Pharma Ltd.(URGN) | 139,079 | 0 | -139,079 | $2.50M | $0 | — | -$2.50M |
| Vera Therapeutics, Inc.(VERA) | 1,368,159 | 0 | -1,368,159 | $55.04M | $0 | — | -$55.04M |
| Veracyte, Inc.(VCYT) | 130,687 | 0 | -130,687 | $4.21M | $0 | — | -$4.21M |
| Waters Corporation(WAT) | 100,000 | 0 | -100,000 | $29.78M | $0 | — | -$29.78M |