Securities ▲▼ | Shares | Value ($K) | |||||
|---|---|---|---|---|---|---|---|
Q4 2025 ▲▼ | Q1 2026 ▲▼ | Change ▲▼ | Q4 2025 ▲▼ | Q1 2026 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| UNITED THERAPEUTICS CORP DEL(UTHR) | 63,580 | 104,726 | +41,146 | 30,979 | 62,100 | 6.94% | +31,121 |
| ENLIVEN THERAPEUTICS INC | 0 | 623,839 | +623,839 | 0 | 24,454 | 2.73% | +24,454 |
| CELCUITY INC(CELC) | 0 | 210,578 | +210,578 | 0 | 24,035 | 2.69% | +24,035 |
| DIANTHUS THERAPEUTICS INC(DNTH) | 0 | 220,921 | +220,921 | 0 | 18,540 | 2.07% | +18,540 |
| PALVELLA THERAPEUTICS INC NE(PVLA) | 0 | 148,093 | +148,093 | 0 | 18,460 | 2.06% | +18,460 |
| ERASCA INC(ERAS) | 0 | 867,639 | +867,639 | 0 | 14,038 | 1.57% | +14,038 |
| XENON PHARMACEUTICALS INC(XENE) | 799,743 | 786,844 | -12,899 | 35,844 | 45,755 | 5.11% | +9,910 |
| ORIC PHARMACEUTICALS INC(ORIC) | 2,010,307 | 2,017,284 | +6,977 | 16,444 | 25,559 | 2.86% | +9,115 |
| APOGEE THERAPEUTICS INC(APGE) | 474,839 | 513,770 | +38,931 | 35,841 | 43,244 | 4.83% | +7,403 |
| ROIVANT SCIENCES LTD(ROIV) | 1,186,817 | 1,190,118 | +3,301 | 25,754 | 32,966 | 3.68% | +7,212 |
| COGENT BIOSCIENCES INC(COGT) | 824,283 | 947,339 | +123,056 | 29,279 | 36,463 | 4.07% | +7,185 |
| BRIDGEBIO PHARMA INC(BBIO) | 595,473 | 695,718 | +100,245 | 45,548 | 51,664 | 5.77% | +6,116 |
| KYMERA THERAPEUTICS INC(KYMR) | 206,445 | 254,672 | +48,227 | 16,063 | 21,212 | 2.37% | +5,148 |
| IDEAYA BIOSCIENCES INC(IDYA) | 723,653 | 873,838 | +150,185 | 25,017 | 29,116 | 3.25% | +4,100 |
| PRAXIS PRECISION MEDICINES I(PRAX) | 35,749 | 42,441 | +6,692 | 10,537 | 13,674 | 1.53% | +3,137 |
| MOONLAKE IMMUNOTHERAPEUTICS(MLTX) | 262,643 | 315,563 | +52,920 | 3,462 | 5,882 | 0.66% | +2,420 |
| UNIQURE NV(QURE) | 321,655 | 615,489 | +293,834 | 7,697 | 10,063 | 1.12% | +2,366 |
| SCHOLAR ROCK HLDG CORP(SRRK) | 459,727 | 446,390 | -13,337 | 20,251 | 21,945 | 2.45% | +1,694 |
| NUVALENT INC(NUVL) | 368,697 | 370,344 | +1,647 | 37,087 | 37,942 | 4.24% | +855 |
| ABIVAX SA(ABVX) | 381,233 | 465,869 | +84,636 | 51,411 | 51,875 | 5.80% | +463 |
| MIRUM PHARMACEUTICALS INC(MIRM) | 481,564 | 400,464 | -81,100 | 38,039 | 36,995 | 4.13% | -1,044 |
| CYTOKINETICS INC(CYTK) | 325,668 | 283,700 | -41,968 | 20,693 | 18,699 | 2.09% | -1,994 |
| NATERA INC(NTRA) | 80,875 | 81,077 | +202 | 18,528 | 16,215 | 1.81% | -2,313 |
| VIRIDIAN THERAPEUTICS INC(VRDN) | 690,528 | 911,337 | +220,809 | 21,489 | 17,826 | 1.99% | -3,663 |
| OLEMA PHARMACEUTICALS INC(OLMA) | 617,714 | 768,662 | +150,948 | 15,443 | 11,461 | 1.28% | -3,982 |
| FULCRUM THERAPEUTICS INC | 1,892,683 | 2,256,109 | +363,426 | 21,406 | 17,304 | 1.93% | -4,102 |
| REVOLUTION MEDICINES INC(RVMD) | 638,385 | 468,376 | -170,009 | 50,847 | 45,550 | 5.09% | -5,298 |
| INSMED INC(INSM) | 264,293 | 248,475 | -15,818 | 45,998 | 40,631 | 4.54% | -5,367 |
| AXSOME THERAPEUTICS INC.(AXSM) | 206,921 | 188,772 | -18,149 | 37,792 | 31,906 | 3.56% | -5,886 |
| ASCENDIS PHARMA A/S(ASND) | 131,808 | 76,300 | -55,508 | 28,107 | 17,452 | 1.95% | -10,655 |
| DISC MEDICINE INC(IRON) | 153,206 | 0 | -153,206 | 12,166 | 0 | — | -12,166 |
| ARCUS BIOSCIENCES INC(RCUS) | 565,142 | 0 | -565,142 | 13,467 | 0 | — | -13,467 |
| NEWAMSTERDAM PHARMA COMPANY ORDINARY SHARES | 893,473 | 558,336 | -335,137 | 31,343 | 17,872 | 2.00% | -13,471 |
| VERA THERAPEUTICS INC(VERA) | 601,774 | 422,023 | -179,751 | 30,474 | 16,978 | 1.90% | -13,496 |
| RHYTHM PHARMACEUTICALS INC(RYTM) | 146,303 | 0 | -146,303 | 15,660 | 0 | — | -15,660 |
| TERNS PHARMACEUTICALS INC | 872,049 | 326,694 | -545,355 | 35,231 | 17,223 | 1.92% | -18,007 |
| ARGENX SE(ARGX) | 23,256 | 0 | -23,256 | 19,557 | 0 | — | -19,557 |
| GUARDANT HEALTH INC(GH) | 271,685 | 0 | -271,685 | 27,750 | 0 | — | -27,750 |