Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q4 2025 ▲▼ | Q1 2026 ▲▼ | Change ▲▼ | Q4 2025 ▲▼ | Q1 2026 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| Scholar Rock Holding Corporation(SRRK) | 10,825,013 | 10,825,013 | 0 | $476.84M | $532.16M | 14.75% | +$55.32M |
| Kymera Therapeutics, Inc.(KYMR) | 3,286,830 | 3,186,830 | -100,000 | $255.75M | $265.43M | 7.36% | +$9.68M |
| Erasca, Inc.(ERAS) | 8,757,249 | 11,244,246 | +2,486,997 | $32.58M | $181.93M | 5.04% | +$149.35M |
| Edgewise Therapeutics, Inc.(EWTX) | 4,529,990 | 4,430,263 | -99,727 | $112.41M | $139.55M | 3.87% | +$27.14M |
| BeOne Medicines AGADS(ONC) | 500,000 | 465,000 | -35,000 | $151.91M | $138.09M | 3.83% | -$13.81M |
| Tango Therapeutics, Inc.(TNGX) | 8,165,374 | 5,657,105 | -2,508,269 | $72.35M | $118.35M | 3.28% | +$46.00M |
| Bicara Therapeutics Inc | 5,216,969 | 5,802,970 | +586,001 | $87.80M | $115.42M | 3.20% | +$27.62M |
| Revolution Medicines, Inc.(RVMD) | 1,335,075 | 1,110,980 | -224,095 | $106.34M | $108.04M | 3.00% | +$1.70M |
| Arrowhead Pharmaceuticals, Inc.(ARWR) | 1,500,476 | 1,615,476 | +115,000 | $99.62M | $101.29M | 2.81% | +$1.67M |
| Veradermics, Incorporated(MANE) | 0 | 1,505,374 | +1,505,374 | $0 | $95.06M | 2.64% | +$95.06M |
| Xenon Pharmaceuticals Inc.(XENE) | 812,761 | 1,318,564 | +505,803 | $36.43M | $76.67M | 2.13% | +$40.25M |
| Olema Pharmaceuticals, Inc.(OLMA) | 3,300,700 | 4,756,949 | +1,456,249 | $82.52M | $70.93M | 1.97% | -$11.59M |
| Crinetics Pharmaceuticals Inc | 1,507,636 | 1,903,636 | +396,000 | $70.18M | $69.14M | 1.92% | -$1.04M |
| Lexicon Pharmaceuticals, Inc.(LXRX) | 38,918,903 | 44,303,518 | +5,384,615 | $44.76M | $69.11M | 1.92% | +$24.36M |
| Cogent Biosciences, Inc.(COGT) | 1,629,279 | 1,709,279 | +80,000 | $57.87M | $65.79M | 1.82% | +$7.92M |
| Stoke Therapeutics, Inc.(STOK) | 2,247,347 | 1,995,347 | -252,000 | $71.33M | $64.97M | 1.80% | -$6.36M |
| Arcus Biosciences, Inc.(RCUS) | 3,007,077 | 3,007,077 | 0 | $71.66M | $64.95M | 1.80% | -$6.71M |
| Structure Therapeutics IncADS | 1,078,698 | 1,328,698 | +250,000 | $75.02M | $64.04M | 1.78% | -$10.98M |
| Disc Medicine, Inc.(IRON) | 988,401 | 988,401 | 0 | $78.49M | $63.20M | 1.75% | -$15.29M |
| Rhythm Pharmaceuticals, Inc.(RYTM) | 499,975 | 725,511 | +225,536 | $53.52M | $63.10M | 1.75% | +$9.58M |
| Solid Biosciences Inc | 7,690,405 | 7,690,405 | 0 | $43.37M | $55.37M | 1.53% | +$12.00M |
| Septerna, Inc.(SEPN) | 2,000,000 | 2,000,000 | 0 | $55.76M | $48.06M | 1.33% | -$7.70M |
| Centessa Pharmaceuticals PLCADS | 4,027,517 | 1,053,464 | -2,974,053 | $100.73M | $41.84M | 1.16% | -$58.88M |
| Spyre Therapeutics, Inc.(SYRE) | 818,598 | 818,598 | 0 | $26.82M | $41.29M | 1.14% | +$14.47M |
| Cytokinetics, Incorporated(CYTK) | 0 | 613,952 | +613,952 | $0 | $40.47M | 1.12% | +$40.47M |
| Dyne Therapeutics, Inc.(DYN) | 3,502,941 | 2,229,125 | -1,273,816 | $68.52M | $40.41M | 1.12% | -$28.10M |
| Taysha Gene Therapies, Inc.(TSHA) | 10,129,913 | 8,829,913 | -1,300,000 | $55.71M | $39.47M | 1.09% | -$16.24M |
| DBV Technologies S.A.ADS(DBVT) | 1,857,362 | 1,857,362 | 0 | $35.61M | $38.80M | 1.08% | +$3.19M |
| ORIC Pharmaceuticals, Inc.(ORIC) | 1,007,575 | 2,998,192 | +1,990,617 | $8.24M | $37.99M | 1.05% | +$29.75M |
| enGene Holdings Inc COM | 3,336,264 | 5,253,159 | +1,916,895 | $30.13M | $35.77M | 0.99% | +$5.65M |
| Palvella Therapeutics, Inc.(PVLA) | 75,000 | 257,485 | +182,485 | $7.85M | $32.10M | 0.89% | +$24.25M |
| Taboola.com Ltd.(TBLA) | 9,969,495 | 9,969,495 | 0 | $45.96M | $30.91M | 0.86% | -$15.05M |
| Enliven Therapeutics Inc | 0 | 746,226 | +746,226 | $0 | $29.25M | 0.81% | +$29.25M |
| Denali Therapeutics Inc.(DNLI) | 1,396,513 | 1,396,513 | 0 | $23.06M | $26.81M | 0.74% | +$3.76M |
| Remitly Global, Inc.(RELY) | 1,618,271 | 1,543,271 | -75,000 | $22.33M | $24.18M | 0.67% | +$1.85M |
| Damora Therapeutics, Inc.(DMRA) | 0 | 900,000 | +900,000 | $0 | $23.31M | 0.65% | +$23.31M |
| Zura Bio LimitedCL A(ZURA) | 1,300,000 | 3,734,866 | +2,434,866 | $6.81M | $22.22M | 0.62% | +$15.41M |
| Annexon, Inc.(ANNX) | 0 | 3,958,646 | +3,958,646 | $0 | $21.93M | 0.61% | +$21.93M |
| Trevi Therapeutics, Inc.(TRVI) | 2,286,867 | 1,786,867 | -500,000 | $28.63M | $21.32M | 0.59% | -$7.31M |
| Rapport Therapeutics, Inc.(RAPP) | 708,469 | 641,469 | -67,000 | $21.49M | $20.07M | 0.56% | -$1.42M |
| Alphabet Inc.CL A(GOOG) | 20,703 | 65,703 | +45,000 | $6.48M | $18.89M | 0.52% | +$12.41M |
| Fulcrum Therapeutics, Inc.(FULC) | 1,950,000 | 2,350,000 | +400,000 | $22.05M | $18.02M | 0.50% | -$4.03M |
| Wave Life Sciences, Inc.SHS(WVE) | 2,450,000 | 2,450,000 | 0 | $41.65M | $17.76M | 0.49% | -$23.89M |
| Definium Therapeutics, Inc.(DFTX) | 0 | 919,493 | +919,493 | $0 | $17.38M | 0.48% | +$17.38M |
| Amylyx Pharmaceuticals, Inc.(AMLX) | 0 | 1,230,000 | +1,230,000 | $0 | $17.10M | 0.47% | +$17.10M |
| Cullinan Therapeutics, Inc.(CGEM) | 1,193,410 | 1,193,410 | 0 | $12.35M | $16.96M | 0.47% | +$4.61M |
| Neumora Therapeutics, Inc.(NMRA) | 6,288,783 | 8,497,822 | +2,209,039 | $11.26M | $16.57M | 0.46% | +$5.31M |
| uniQure N.V.SHS(QURE) | 0 | 1,000,000 | +1,000,000 | $0 | $16.35M | 0.45% | +$16.35M |
| CytomX Therapeutics, Inc.(CTMX) | 0 | 3,457,711 | +3,457,711 | $0 | $16.25M | 0.45% | +$16.25M |
| NVIDIA Corporation(NVDA) | 37,485 | 89,085 | +51,600 | $6.99M | $15.54M | 0.43% | +$8.55M |
| Silence Therapeutics plcADS(SLN) | 2,911,438 | 2,911,438 | 0 | $17.70M | $15.34M | 0.43% | -$2.36M |
| Microsoft Corporation(MSFT) | 15,000 | 41,380 | +26,380 | $7.25M | $15.32M | 0.42% | +$8.06M |
| Monopar Therapeutics Inc.(MNPR) | 212,298 | 270,118 | +57,820 | $13.86M | $14.80M | 0.41% | +$936.7K |
| Taiwan Semiconductor Manufacturing Company LimitedADS(TSM) | 27,700 | 42,200 | +14,500 | $8.42M | $14.26M | 0.40% | +$5.84M |
| Sionna Therapeutics, Inc.(SION) | 300,000 | 300,000 | 0 | $12.34M | $12.03M | 0.33% | -$315.0K |
| Nebius Group N.V.CL A(NBIS) | 76,218 | 113,614 | +37,396 | $6.38M | $11.79M | 0.33% | +$5.41M |
| Rezolute, Inc.(RZLT) | 0 | 3,328,287 | +3,328,287 | $0 | $10.15M | 0.28% | +$10.15M |
| Inhibikase Therapeutics, Inc.(IKT) | 5,850,000 | 5,850,000 | 0 | $11.99M | $9.83M | 0.27% | -$2.16M |
| Amazon.com, Inc.(AMZN) | 51,500 | 46,641 | -4,859 | $11.89M | $9.71M | 0.27% | -$2.17M |
| Generate Biomedicines, Inc.(GENB) | 0 | 736,104 | +736,104 | $0 | $9.20M | 0.26% | +$9.20M |
| MapLight Therapeutics, Inc.(MPLT) | 450,000 | 450,000 | 0 | $7.90M | $9.15M | 0.25% | +$1.24M |
| ServiceNow, Inc.(NOW) | 35,630 | 87,090 | +51,460 | $5.46M | $9.11M | 0.25% | +$3.65M |
| CrowdStrike Holdings, Inc.CL A(CRWD) | 16,500 | 23,070 | +6,570 | $7.73M | $9.01M | 0.25% | +$1.27M |
| PDD Holdings Inc.ADS(PDD) | 63,401 | 83,401 | +20,000 | $7.19M | $8.52M | 0.24% | +$1.33M |
| Tesla, Inc.(TSLA) | 1,500 | 21,500 | +20,000 | $674.6K | $7.99M | 0.22% | +$7.32M |
| NovaBridge BiosciencesADS(NBP) | 3,000,000 | 3,000,000 | 0 | $11.94M | $7.38M | 0.20% | -$4.56M |
| Bicycle Therapeutics PLCADS | 2,012,752 | 1,560,882 | -451,870 | $14.25M | $7.24M | 0.20% | -$7.01M |
| Whitehawk Therapeutics, Inc.(WHWK) | 2,082,000 | 2,082,000 | 0 | $5.04M | $7.18M | 0.20% | +$2.14M |
| Tenax Therapeutics, Inc.(TENX) | 427,141 | 427,141 | 0 | $5.21M | $6.83M | 0.19% | +$1.62M |
| vTv Therapeutics Inc.CL A(VTVT) | 163,000 | 163,000 | 0 | $6.52M | $6.46M | 0.18% | -$53.8K |
| Datadog, Inc.CL A(DDOG) | 36,425 | 54,300 | +17,875 | $4.95M | $6.41M | 0.18% | +$1.46M |
| JFrog Ltd.(FROG) | 93,616 | 128,816 | +35,200 | $5.85M | $6.05M | 0.17% | +$198.1K |
| Dynatrace, Inc.(DT) | 115,229 | 150,000 | +34,771 | $4.99M | $5.55M | 0.15% | +$553.0K |
| Workiva Inc.CL A(WK) | 79,123 | 92,500 | +13,377 | $6.82M | $5.52M | 0.15% | -$1.31M |
| Absci Corp | 0 | 1,800,000 | +1,800,000 | $0 | $5.40M | 0.15% | +$5.40M |
| Invivyd, Inc.(IVVD) | 4,000,000 | 4,000,000 | 0 | $9.88M | $5.20M | 0.14% | -$4.68M |
| Satellos Bioscience Inc.(MSLE) | 0 | 892,074 | +892,074 | $0 | $5.02M | 0.14% | +$5.02M |
| IonQ, Inc.(IONQ) | 170,000 | 170,000 | 0 | $7.63M | $4.90M | 0.14% | -$2.73M |
| Broadcom Inc.(AVGO) | 7,000 | 15,000 | +8,000 | $2.42M | $4.64M | 0.13% | +$2.22M |
| AgomAb Therapeutics NVADS(AGMB) | 0 | 411,250 | +411,250 | $0 | $4.31M | 0.12% | +$4.31M |
| Cellebrite DI Ltd.(CLBT) | 150,000 | 311,544 | +161,544 | $2.71M | $4.29M | 0.12% | +$1.59M |
| Seer, Inc.CL A(SEER) | 4,000,000 | 2,458,673 | -1,541,327 | $7.32M | $4.13M | 0.11% | -$3.19M |
| Korro Bio, Inc.(KRRO) | 347,718 | 347,718 | 0 | $2.79M | $3.94M | 0.11% | +$1.15M |
| Agenus Inc.(AGEN) | 1,064,250 | 1,064,250 | 0 | $3.34M | $3.55M | 0.10% | +$212.8K |
| Foghorn Therapeutics Inc.(FHTX) | 720,720 | 720,720 | 0 | $3.89M | $3.45M | 0.10% | -$446.8K |
| Forgent Power Solutions, Inc.CL A(FPS) | 0 | 100,000 | +100,000 | $0 | $2.93M | 0.08% | +$2.93M |
| Kalaris Therapeutics, Inc.(KLRS) | 435,798 | 435,798 | 0 | $3.68M | $2.51M | 0.07% | -$1.16M |
| GitLab Inc.CL A(GTLB) | 99,000 | 100,000 | +1,000 | $3.72M | $2.16M | 0.06% | -$1.55M |
| Micron Technology, Inc.(MU) | 0 | 6,000 | +6,000 | $0 | $2.03M | 0.06% | +$2.03M |
| monday.com LtdSHS SHS | 17,000 | 25,000 | +8,000 | $2.51M | $1.73M | 0.05% | -$780.8K |
| Gossamer Bio, Inc.(GOSS) | 5,208,968 | 5,208,968 | 0 | $16.15M | $1.71M | 0.05% | -$14.44M |
| Amer Sports, Inc.(AS) | 0 | 50,000 | +50,000 | $0 | $1.65M | 0.05% | +$1.65M |
| KE Holdings Inc.ADS(BEKE) | 145,000 | 100,000 | -45,000 | $2.29M | $1.50M | 0.04% | -$788.2K |
| IREN Ltd ORDINARY SHARES | 43,100 | 43,100 | 0 | $1.63M | $1.48M | 0.04% | -$150.4K |
| Rani Therapeutics Holdings, Inc.CL A(RANI) | 2,000,000 | 2,000,000 | 0 | $2.70M | $1.47M | 0.04% | -$1.23M |
| Aeva Technologies, Inc.(AEVA) | 0 | 110,000 | +110,000 | $0 | $1.45M | 0.04% | +$1.45M |
| Medline Inc.CL A(MDLN) | 75,000 | 25,000 | -50,000 | $3.15M | $1.11M | 0.03% | -$2.04M |
| Figma, Inc.CL A(FIG) | 25,000 | 50,000 | +25,000 | $934.3K | $1.06M | 0.03% | +$122.8K |
| Primo Brands CorporationCL A(PRMB) | 75,000 | 50,000 | -25,000 | $1.23M | $941.5K | 0.03% | -$284.8K |
| Nu Holdings Ltd.CL A(NU) | 0 | 25,000 | +25,000 | $0 | $359.3K | 0.01% | +$359.3K |