Securities ▲▼ | Shares | Value ($K) | |||||
|---|---|---|---|---|---|---|---|
Q1 2025 ▲▼ | Q2 2025 ▲▼ | Change ▲▼ | Q1 2025 ▲▼ | Q2 2025 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| Kymera Therapeutics Inc(KYMR) | 3,240,313 | 3,428,150 | +187,837 | 88,687 | 149,604 | 7.74% | +60,917 |
| Scholar Rock Holding Corp(SRRK) | 9,250,005 | 9,250,005 | 0 | 297,388 | 327,635 | 16.95% | +30,248 |
| MoonLake Immunotherapeutics(MLTX) | 0 | 508,267 | +508,267 | 0 | 23,990 | 1.24% | +23,990 |
| Lexicon Pharmaceuticals Inc(LXRX) | 38,918,903 | 38,918,903 | 0 | 17,934 | 36,806 | 1.90% | +18,872 |
| Dyne Therapeutics Inc(DYN) | 2,717,987 | 4,836,437 | +2,118,450 | 28,430 | 46,043 | 2.38% | +17,613 |
| Akero Therapeutics Inc | 0 | 318,647 | +318,647 | 0 | 17,003 | 0.88% | +17,003 |
| Taysha Gene Therapies Inc(TSHA) | 6,514,737 | 11,014,737 | +4,500,000 | 9,055 | 25,444 | 1.32% | +16,389 |
| Arrivent Biopharma Inc(AVBP) | 0 | 700,000 | +700,000 | 0 | 15,239 | 0.79% | +15,239 |
| Revolution Medicines Inc(RVMD) | 563,755 | 938,755 | +375,000 | 19,934 | 34,537 | 1.79% | +14,602 |
| Tango Therapeutics Inc(TNGX) | 2,565,342 | 3,364,814 | +799,472 | 3,515 | 17,228 | 0.89% | +13,713 |
| Rhythm Pharmaceuticals Inc(RYTM) | 277,533 | 409,742 | +132,209 | 14,701 | 25,892 | 1.34% | +11,191 |
| Stoke Therapeutics Inc(STOK) | 2,247,347 | 2,247,347 | 0 | 14,945 | 25,507 | 1.32% | +10,563 |
| Septerna Inc(SEPN) | 2,202,514 | 2,202,514 | 0 | 12,753 | 23,281 | 1.20% | +10,528 |
| Silence Therapeutics PLC(SLN) | 2,789,833 | 2,911,438 | +121,605 | 7,867 | 16,886 | 0.87% | +9,019 |
| Solid Biosciences Inc | 7,415,905 | 7,415,905 | 0 | 27,439 | 36,115 | 1.87% | +8,677 |
| Arrowhead Pharmaceuticals Inc(ARWR) | 2,669,880 | 2,669,880 | 0 | 34,014 | 42,184 | 2.18% | +8,170 |
| Taboola.com Ltd(TBLA) | 9,969,495 | 9,969,495 | 0 | 29,410 | 36,488 | 1.89% | +7,078 |
| Cogent Biosciences Inc(COGT) | 0 | 854,379 | +854,379 | 0 | 6,134 | 0.32% | +6,134 |
| Bicara Therapeutics Inc | 3,267,083 | 5,216,969 | +1,949,886 | 42,570 | 48,466 | 2.51% | +5,896 |
| Pacira Biosciences Inc(PCRX) | 0 | 225,000 | +225,000 | 0 | 5,378 | 0.28% | +5,378 |
| Disc Medicine Inc(IRON) | 1,071,865 | 1,099,401 | +27,536 | 53,207 | 58,224 | 3.01% | +5,017 |
| Oric Pharmaceuticals Inc(ORIC) | 1,007,575 | 1,007,575 | 0 | 5,622 | 10,227 | 0.53% | +4,605 |
| Agenus Inc(AGEN) | 500,000 | 1,064,250 | +564,250 | 753 | 4,864 | 0.25% | +4,111 |
| Edgewise Therapeutics Inc(EWTX) | 1,696,444 | 3,160,298 | +1,463,854 | 37,322 | 41,432 | 2.14% | +4,110 |
| Upstream Bio Inc(UPB) | 788,450 | 788,450 | 0 | 4,825 | 8,657 | 0.45% | +3,832 |
| Apogee Therapeutics Inc(APGE) | 594,994 | 594,994 | 0 | 22,229 | 25,841 | 1.34% | +3,612 |
| IONQ Inc(IONQ) | 170,000 | 170,000 | 0 | 3,752 | 7,305 | 0.38% | +3,553 |
| Trevi Therapeutics Inc(TRVI) | 2,863,793 | 3,938,793 | +1,075,000 | 18,013 | 21,545 | 1.11% | +3,532 |
| Sagimet Biosciences Inc(SGMT) | 724,771 | 724,771 | 0 | 2,363 | 5,523 | 0.29% | +3,160 |
| NVIDIA Corp(NVDA) | 44,432 | 49,985 | +5,553 | 4,816 | 7,897 | 0.41% | +3,082 |
| Centessa Pharmaceuticals PLC | 2,960,029 | 3,460,029 | +500,000 | 42,565 | 45,465 | 2.35% | +2,900 |
| Salesforce Inc(CRM) | 14,600 | 22,600 | +8,000 | 3,918 | 6,163 | 0.32% | +2,245 |
| Sionna Therapeutics Inc(SION) | 325,000 | 325,000 | 0 | 3,400 | 5,639 | 0.29% | +2,239 |
| Taiwan Semiconductor Manufacturing Co Ltd(TSM) | 28,500 | 30,500 | +2,000 | 4,731 | 6,908 | 0.36% | +2,177 |
| Seer Inc(SEER) | 4,000,000 | 4,000,000 | 0 | 6,760 | 8,560 | 0.44% | +1,800 |
| HubSpot Inc(HUBS) | 0 | 3,000 | +3,000 | 0 | 1,670 | 0.09% | +1,670 |
| Amazon.com Inc(AMZN) | 56,500 | 56,500 | 0 | 10,750 | 12,396 | 0.64% | +1,646 |
| UnitedHealth Group Inc(UNH) | 0 | 5,076 | +5,076 | 0 | 1,584 | 0.08% | +1,584 |
| GitLab Inc(GTLB) | 0 | 35,000 | +35,000 | 0 | 1,579 | 0.08% | +1,579 |
| Birkenstock Holding PLC(BIRK) | 0 | 25,000 | +25,000 | 0 | 1,230 | 0.06% | +1,230 |
| Primo Brands Corp(PRMB) | 0 | 37,500 | +37,500 | 0 | 1,111 | 0.06% | +1,111 |
| ProQR Therapeutics NV SHS EURO | 1,552,183 | 1,552,183 | 0 | 2,064 | 3,166 | 0.16% | +1,102 |
| Alphabet Inc(GOOG) | 50,703 | 50,703 | 0 | 7,841 | 8,934 | 0.46% | +1,093 |
| Black Diamond Therapeutics Inc | 1,046,517 | 1,046,517 | 0 | 1,622 | 2,595 | 0.13% | +973 |
| Merus NV | 1,043,467 | 853,467 | -190,000 | 43,920 | 44,892 | 2.32% | +973 |
| Cellebrite DI Ltd(CLBT) | 0 | 60,000 | +60,000 | 0 | 960 | 0.05% | +960 |
| Xenon Pharmaceuticals Inc(XENE) | 732,761 | 812,761 | +80,000 | 24,584 | 25,439 | 1.32% | +855 |
| IHS Holding Limited ORD SHS | 2,357,520 | 2,357,520 | 0 | 12,306 | 13,108 | 0.68% | +802 |
| Foghorn Therapeutics Inc(FHTX) | 720,720 | 720,720 | 0 | 2,631 | 3,387 | 0.18% | +757 |
| Atlassian Corp | 0 | 3,500 | +3,500 | 0 | 711 | 0.04% | +711 |
| Instil Bio Inc(TIL) | 203,933 | 203,933 | 0 | 3,540 | 4,248 | 0.22% | +708 |
| Gossamer Bio Inc(GOSS) | 5,208,968 | 5,208,968 | 0 | 5,730 | 6,407 | 0.33% | +677 |
| CrowdStrike Holdings Inc(CRWD) | 25,000 | 18,500 | -6,500 | 8,815 | 9,422 | 0.49% | +608 |
| Workiva Inc(WK) | 17,500 | 28,000 | +10,500 | 1,328 | 1,917 | 0.10% | +588 |
| Rapport Therapeutics Inc(RAPP) | 378,469 | 378,469 | 0 | 3,796 | 4,303 | 0.22% | +507 |
| Jfrog Ltd(FROG) | 131,616 | 107,116 | -24,500 | 4,212 | 4,700 | 0.24% | +489 |
| CCC Intelligent Solutions Holdings Inc(CCC) | 0 | 50,000 | +50,000 | 0 | 471 | 0.02% | +471 |
| Arcus Biosciences Inc(RCUS) | 1,612,077 | 1,612,077 | 0 | 12,655 | 13,122 | 0.68% | +468 |
| Datadog Inc(DDOG) | 47,425 | 38,425 | -9,000 | 4,705 | 5,162 | 0.27% | +457 |
| Palo Alto Networks Inc(PANW) | 11,500 | 11,500 | 0 | 1,962 | 2,353 | 0.12% | +391 |
| PG&E Corp(PCG) | 0 | 25,000 | +25,000 | 0 | 349 | 0.02% | +349 |
| Lexeo Therapeutics Inc(LXEO) | 603,435 | 603,435 | 0 | 2,094 | 2,426 | 0.13% | +332 |
| Denali Therapeutics Inc(DNLI) | 821,513 | 821,513 | 0 | 11,168 | 11,493 | 0.59% | +324 |
| Vertiv Holdings Co(VRT) | 0 | 2,000 | +2,000 | 0 | 257 | 0.01% | +257 |
| Whitehawk Therapeutics Inc(WHWK) | 2,082,000 | 2,082,000 | 0 | 3,706 | 3,893 | 0.20% | +187 |
| BIOAGE Labs Inc(BIOA) | 382,406 | 382,406 | 0 | 1,438 | 1,579 | 0.08% | +141 |
| HOOKIPA Pharma Inc | 566,640 | 566,640 | 0 | 612 | 711 | 0.04% | +99 |
| New Oriental Education & Technology Group Inc(EDU) | 79,500 | 72,000 | -7,500 | 3,801 | 3,884 | 0.20% | +84 |
| Qualcomm Inc(QCOM) | 14,000 | 14,000 | 0 | 2,151 | 2,230 | 0.12% | +79 |
| Tourmaline Bio Inc | 91,426 | 91,426 | 0 | 1,391 | 1,462 | 0.08% | +71 |
| Cyclerion Therapeutics Inc(CYCN) | 116,155 | 116,155 | 0 | 290 | 338 | 0.02% | +48 |
| Caribou Biosciences Inc(CRBU) | 105,347 | 105,347 | 0 | 96 | 133 | 0.01% | +37 |
| Procore Technologies Inc(PCOR) | 10,000 | 10,000 | 0 | 660 | 684 | 0.04% | +24 |
| Dynatrace Inc(DT) | 87,729 | 75,229 | -12,500 | 4,136 | 4,153 | 0.21% | +17 |
| SEMrush Holdings Inc CL A COM | 125,000 | 125,000 | 0 | 1,166 | 1,131 | 0.06% | -35 |
| Cullinan Therapeutics Inc(CGEM) | 1,193,410 | 1,193,410 | 0 | 9,034 | 8,986 | 0.47% | -48 |
| Ironwood Pharmaceuticals Inc(IRWD) | 110,532 | 110,532 | 0 | 162 | 80 | 0.00% | -83 |
| IGM Biosciences Inc | 3,255,826 | 3,255,826 | 0 | 3,744 | 3,647 | 0.19% | -98 |
| Nebius Group NV(NBIS) | 140,000 | 51,000 | -89,000 | 2,955 | 2,822 | 0.15% | -134 |
| Vigil Neuroscience Inc | 1,967,064 | 411,191 | -1,555,873 | 3,501 | 3,269 | 0.17% | -232 |
| Ke Holdings Inc(BEKE) | 105,000 | 105,000 | 0 | 2,109 | 1,863 | 0.10% | -247 |
| Generation Bio Co | 2,968,925 | 2,968,925 | 0 | 1,202 | 950 | 0.05% | -252 |
| GDS Holdings Ltd(GDS) | 12,500 | 0 | -12,500 | 317 | 0 | — | -317 |
| Deckers Outdoor Corp(DECK) | 5,000 | 2,000 | -3,000 | 559 | 206 | 0.01% | -353 |
| Spyre Therapeutics Inc(SYRE) | 368,598 | 368,598 | 0 | 5,947 | 5,518 | 0.29% | -429 |
| Eledon Pharmaceuticals Inc(ELDN) | 690,170 | 690,170 | 0 | 2,340 | 1,870 | 0.10% | -469 |
| Occidental Petroleum Corp(OXY) | 10,000 | 0 | -10,000 | 494 | 0 | — | -494 |
| Remitly Global Inc(RELY) | 490,449 | 515,449 | +25,000 | 10,201 | 9,675 | 0.50% | -526 |
| US Bancorp(USB) | 12,500 | 0 | -12,500 | 528 | 0 | — | -528 |
| Ferrari NV COM | 1,500 | 0 | -1,500 | 636 | 0 | — | -636 |
| SailPoint Inc(SAIL) | 95,000 | 50,000 | -45,000 | 1,781 | 1,143 | 0.06% | -638 |
| Kronos Bio Inc | 842,954 | 0 | -842,954 | 695 | 0 | — | -695 |
| PDD Holdings Inc(PDD) | 52,901 | 52,901 | 0 | 6,261 | 5,537 | 0.29% | -724 |
| Couchbase Inc | 49,850 | 0 | -49,850 | 785 | 0 | — | -785 |
| Boeing Co(BA) | 5,000 | 0 | -5,000 | 853 | 0 | — | -853 |
| Informatica Inc | 50,000 | 0 | -50,000 | 873 | 0 | — | -872 |
| Erasca Inc(ERAS) | 8,757,249 | 8,757,249 | 0 | 11,997 | 11,122 | 0.58% | -876 |
| Intel Corp(INTC) | 40,000 | 0 | -40,000 | 908 | 0 | — | -908 |
| Nike Inc(NKE) | 15,000 | 0 | -15,000 | 952 | 0 | — | -952 |
| MongoDB Inc(MDB) | 5,500 | 0 | -5,500 | 965 | 0 | — | -965 |