Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q2 2025 ▲▼ | Q3 2025 ▲▼ | Change ▲▼ | Q2 2025 ▲▼ | Q3 2025 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| Scholar Rock Holding Corporation(SRRK) | 9,250,005 | 9,250,005 | 0 | $327.64M | $344.47M | 13.48% | +$16.84M |
| Kymera Therapeutics, Inc.(KYMR) | 3,428,150 | 3,428,150 | 0 | $149.60M | $194.03M | 7.59% | +$44.43M |
| BeOne Medicines AGADS(ONC) | 509,990 | 492,990 | -17,000 | $123.45M | $167.96M | 6.57% | +$44.51M |
| Arrowhead Pharmaceuticals, Inc.(ARWR) | 2,669,880 | 2,669,880 | 0 | $42.18M | $92.08M | 3.60% | +$49.90M |
| Bicara Therapeutics Inc | 5,216,969 | 5,216,969 | 0 | $48.47M | $82.38M | 3.22% | +$33.91M |
| Centessa Pharmaceuticals PLCADS | 3,460,029 | 3,227,517 | -232,512 | $45.46M | $78.27M | 3.06% | +$32.80M |
| Crinetics Pharmaceuticals Inc | 1,688,611 | 1,688,611 | 0 | $48.56M | $70.33M | 2.75% | +$21.77M |
| Edgewise Therapeutics, Inc.(EWTX) | 3,160,298 | 3,897,099 | +736,801 | $41.43M | $63.21M | 2.47% | +$21.78M |
| Disc Medicine, Inc.(IRON) | 1,099,401 | 913,401 | -186,000 | $58.22M | $60.36M | 2.36% | +$2.13M |
| Dyne Therapeutics, Inc.(DYN) | 4,836,437 | 4,729,174 | -107,263 | $46.04M | $59.82M | 2.34% | +$13.78M |
| Apellis Pharmaceuticals Inc COM | 2,578,396 | 2,578,396 | 0 | $44.63M | $58.35M | 2.28% | +$13.72M |
| Avidity Biosciences Inc | 1,110,610 | 1,285,610 | +175,000 | $31.54M | $56.01M | 2.19% | +$24.47M |
| Stoke Therapeutics, Inc.(STOK) | 2,247,347 | 2,247,347 | 0 | $25.51M | $52.81M | 2.07% | +$27.31M |
| Lexicon Pharmaceuticals, Inc.(LXRX) | 38,918,903 | 38,918,903 | 0 | $36.81M | $52.54M | 2.06% | +$15.73M |
| Rhythm Pharmaceuticals, Inc.(RYTM) | 409,742 | 499,975 | +90,233 | $25.89M | $50.49M | 1.98% | +$24.60M |
| Tango Therapeutics, Inc.(TNGX) | 3,364,814 | 5,883,188 | +2,518,374 | $17.23M | $49.42M | 1.93% | +$32.19M |
| Revolution Medicines, Inc.(RVMD) | 938,755 | 1,043,720 | +104,965 | $34.54M | $48.74M | 1.91% | +$14.20M |
| Ascendis Pharma A/SADR(ASND) | 245,943 | 235,862 | -10,081 | $42.45M | $46.89M | 1.83% | +$4.44M |
| Rezolute, Inc.(RZLT) | 0 | 4,870,000 | +4,870,000 | $0 | $45.78M | 1.79% | +$45.78M |
| Solid Biosciences Inc | 7,415,905 | 7,415,905 | 0 | $36.12M | $45.76M | 1.79% | +$9.64M |
| Septerna, Inc.(SEPN) | 2,202,514 | 2,202,514 | 0 | $23.28M | $41.43M | 1.62% | +$18.15M |
| Arcus Biosciences, Inc.(RCUS) | 1,612,077 | 2,912,077 | +1,300,000 | $13.12M | $39.60M | 1.55% | +$26.48M |
| Taysha Gene Therapies, Inc.(TSHA) | 11,014,737 | 11,014,737 | 0 | $25.44M | $36.02M | 1.41% | +$10.57M |
| Taboola.com Ltd.(TBLA) | 9,969,495 | 9,969,495 | 0 | $36.49M | $34.00M | 1.33% | -$2.49M |
| Xenon Pharmaceuticals Inc.(XENE) | 812,761 | 812,761 | 0 | $25.44M | $32.63M | 1.28% | +$7.19M |
| Soleno Therapeutics Inc | 467,342 | 467,342 | 0 | $39.15M | $31.59M | 1.24% | -$7.56M |
| Rapport Therapeutics, Inc.(RAPP) | 378,469 | 1,053,469 | +675,000 | $4.30M | $31.29M | 1.22% | +$26.98M |
| Structure Therapeutics IncADS | 0 | 1,026,811 | +1,026,811 | $0 | $28.75M | 1.12% | +$28.75M |
| Wave Life Sciences, Inc.SHS(WVE) | 3,696,322 | 3,696,322 | 0 | $24.03M | $27.06M | 1.06% | +$3.03M |
| Remitly Global, Inc.(RELY) | 515,449 | 1,618,271 | +1,102,822 | $9.67M | $26.38M | 1.03% | +$16.70M |
| Cogent Biosciences, Inc.(COGT) | 854,379 | 1,724,279 | +869,900 | $6.13M | $24.76M | 0.97% | +$18.63M |
| Trevi Therapeutics, Inc.(TRVI) | 3,938,793 | 2,536,867 | -1,401,926 | $21.55M | $23.21M | 0.91% | +$1.67M |
| NewAmsterdam Pharma Company NV ORDINARY SHARES | 1,194,240 | 765,705 | -428,535 | $21.63M | $21.78M | 0.85% | +$149.0K |
| Korro Bio, Inc.(KRRO) | 418,833 | 418,833 | 0 | $5.23M | $20.06M | 0.78% | +$14.83M |
| Erasca, Inc.(ERAS) | 8,757,249 | 8,757,249 | 0 | $11.12M | $19.09M | 0.75% | +$7.97M |
| IHS Holding Limited ORD SHS | 2,357,520 | 2,357,520 | 0 | $13.11M | $16.08M | 0.63% | +$2.97M |
| uniQure N.V.SHS(QURE) | 0 | 275,200 | +275,200 | $0 | $16.06M | 0.63% | +$16.06M |
| Bicycle Therapeutics PLCADS | 2,012,752 | 2,012,752 | 0 | $13.99M | $15.58M | 0.61% | +$1.59M |
| Silence Therapeutics plcADS(SLN) | 2,911,438 | 2,911,438 | 0 | $16.89M | $15.11M | 0.59% | -$1.78M |
| RAPT Therapeutics Inc | 0 | 580,466 | +580,466 | $0 | $14.97M | 0.59% | +$14.97M |
| Upstream Bio, Inc.(UPB) | 788,450 | 788,450 | 0 | $8.66M | $14.83M | 0.58% | +$6.17M |
| Gossamer Bio, Inc.(GOSS) | 5,208,968 | 5,208,968 | 0 | $6.41M | $13.70M | 0.54% | +$7.29M |
| ArriVent BioPharma, Inc.(AVBP) | 700,000 | 700,000 | 0 | $15.24M | $12.91M | 0.51% | -$2.32M |
| Amazon.com, Inc.(AMZN) | 56,500 | 58,500 | +2,000 | $12.40M | $12.84M | 0.50% | +$449.3K |
| ORIC Pharmaceuticals, Inc.(ORIC) | 1,007,575 | 1,007,575 | 0 | $10.23M | $12.09M | 0.47% | +$1.86M |
| Denali Therapeutics Inc.(DNLI) | 821,513 | 821,513 | 0 | $11.49M | $11.93M | 0.47% | +$435.4K |
| IonQ, Inc.(IONQ) | 170,000 | 170,000 | 0 | $7.30M | $10.46M | 0.41% | +$3.15M |
| Sionna Therapeutics, Inc.(SION) | 325,000 | 325,000 | 0 | $5.64M | $9.56M | 0.37% | +$3.92M |
| CrowdStrike Holdings, Inc.CL A(CRWD) | 18,500 | 18,500 | 0 | $9.42M | $9.07M | 0.35% | -$350.2K |
| Microsoft Corporation(MSFT) | 16,150 | 17,150 | +1,000 | $8.03M | $8.88M | 0.35% | +$849.7K |
| Seer, Inc.CL A(SEER) | 4,000,000 | 4,000,000 | 0 | $8.56M | $8.68M | 0.34% | +$120.0K |
| Nebius Group N.V.CL A(NBIS) | 51,000 | 72,600 | +21,600 | $2.82M | $8.15M | 0.32% | +$5.33M |
| Neumora Therapeutics, Inc.(NMRA) | 4,358,283 | 4,358,283 | 0 | $3.20M | $7.93M | 0.31% | +$4.74M |
| Taiwan Semiconductor Manufacturing Company LimitedADS(TSM) | 30,500 | 28,200 | -2,300 | $6.91M | $7.88M | 0.31% | +$968.0K |
| Salesforce, Inc.(CRM) | 22,600 | 30,100 | +7,500 | $6.16M | $7.13M | 0.28% | +$970.9K |
| Cullinan Therapeutics, Inc.(CGEM) | 1,193,410 | 1,193,410 | 0 | $8.99M | $7.08M | 0.28% | -$1.91M |
| NVIDIA Corporation(NVDA) | 49,985 | 37,485 | -12,500 | $7.90M | $6.99M | 0.27% | -$903.4K |
| ServiceNow, Inc.(NOW) | 5,126 | 7,126 | +2,000 | $5.27M | $6.56M | 0.26% | +$1.29M |
| Spyre Therapeutics, Inc.(SYRE) | 368,598 | 368,598 | 0 | $5.52M | $6.18M | 0.24% | +$659.8K |
| Cartesian Therapeutics, Inc.(RNAC) | 563,272 | 563,272 | 0 | $5.85M | $5.76M | 0.23% | -$95.8K |
| PDD Holdings Inc.ADS(PDD) | 52,901 | 43,401 | -9,500 | $5.54M | $5.74M | 0.22% | +$199.7K |
| Eledon Pharmaceuticals, Inc.(ELDN) | 690,170 | 2,072,767 | +1,382,597 | $1.87M | $5.37M | 0.21% | +$3.50M |
| Adobe Inc.(ADBE) | 15,051 | 15,051 | 0 | $5.82M | $5.31M | 0.21% | -$513.7K |
| Alphabet Inc.CL A(GOOG) | 50,703 | 21,203 | -29,500 | $8.93M | $5.15M | 0.20% | -$3.78M |
| JFrog Ltd.(FROG) | 107,116 | 107,116 | 0 | $4.70M | $5.07M | 0.20% | +$369.6K |
| Sagimet Biosciences Inc.COM SER A(SGMT) | 724,771 | 724,771 | 0 | $5.52M | $4.97M | 0.19% | -$550.8K |
| Dynatrace, Inc.(DT) | 75,229 | 100,229 | +25,000 | $4.15M | $4.86M | 0.19% | +$702.7K |
| Datadog, Inc.CL A(DDOG) | 38,425 | 32,925 | -5,500 | $5.16M | $4.69M | 0.18% | -$473.1K |
| NovaBridge BiosciencesADS(NBP) | 0 | 1,165,957 | +1,165,957 | $0 | $4.41M | 0.17% | +$4.41M |
| Agenus Inc.(AGEN) | 1,064,250 | 1,064,250 | 0 | $4.86M | $4.10M | 0.16% | -$766.3K |
| Lexeo Therapeutics, Inc.(LXEO) | 603,435 | 603,435 | 0 | $2.43M | $4.01M | 0.16% | +$1.58M |
| Black Diamond Therapeutics Inc | 1,046,517 | 1,046,517 | 0 | $2.60M | $3.97M | 0.16% | +$1.37M |
| Whitehawk Therapeutics, Inc.(WHWK) | 2,082,000 | 2,082,000 | 0 | $3.89M | $3.96M | 0.15% | +$62.5K |
| vTv Therapeutics Inc.CL A(VTVT) | 0 | 163,000 | +163,000 | $0 | $3.81M | 0.15% | +$3.81M |
| Instil Bio, Inc.(TIL) | 203,933 | 203,933 | 0 | $4.25M | $3.64M | 0.14% | -$605.7K |
| Foghorn Therapeutics Inc.(FHTX) | 720,720 | 720,720 | 0 | $3.39M | $3.52M | 0.14% | +$136.9K |
| ProQR Therapeutics NVSHS EURO SHS EURO | 1,552,183 | 1,552,183 | 0 | $3.17M | $3.31M | 0.13% | +$139.7K |
| New Oriental Education & Technology Group Inc.ADR(EDU) | 72,000 | 62,000 | -10,000 | $3.88M | $3.29M | 0.13% | -$594.1K |
| CoreWeave, Inc.CL A(CRWV) | 0 | 24,000 | +24,000 | $0 | $3.28M | 0.13% | +$3.28M |
| PepGen Inc.(PEPG) | 0 | 700,000 | +700,000 | $0 | $3.23M | 0.13% | +$3.23M |
| GitLab Inc.CL A(GTLB) | 35,000 | 64,000 | +29,000 | $1.58M | $2.89M | 0.11% | +$1.31M |
| KE Holdings Inc.ADS(BEKE) | 105,000 | 145,000 | +40,000 | $1.86M | $2.75M | 0.11% | +$892.3K |
| Palo Alto Networks, Inc.(PANW) | 11,500 | 13,450 | +1,950 | $2.35M | $2.74M | 0.11% | +$385.3K |
| Tenax Therapeutics, Inc.(TENX) | 0 | 352,441 | +352,441 | $0 | $2.68M | 0.10% | +$2.68M |
| Workiva Inc.CL A(WK) | 28,000 | 30,000 | +2,000 | $1.92M | $2.58M | 0.10% | +$665.8K |
| QUALCOMM Incorporated(QCOM) | 14,000 | 14,000 | 0 | $2.23M | $2.33M | 0.09% | +$99.4K |
| BioAge Labs, Inc.(BIOA) | 382,406 | 382,406 | 0 | $1.58M | $2.25M | 0.09% | +$669.2K |
| Keurig Dr Pepper Inc.(KDP) | 0 | 77,050 | +77,050 | $0 | $1.97M | 0.08% | +$1.97M |
| HubSpot, Inc.(HUBS) | 3,000 | 4,000 | +1,000 | $1.67M | $1.87M | 0.07% | +$201.3K |
| Chipotle Mexican Grill, Inc.(CMG) | 0 | 47,500 | +47,500 | $0 | $1.86M | 0.07% | +$1.86M |
| Kalaris Therapeutics, Inc.(KLRS) | 282,586 | 318,264 | +35,678 | $754.5K | $1.84M | 0.07% | +$1.09M |
| Generation Bio Co | 0 | 296,892 | +296,892 | $0 | $1.82M | 0.07% | +$1.82M |
| Cellebrite DI Ltd.(CLBT) | 60,000 | 90,000 | +30,000 | $960.0K | $1.67M | 0.07% | +$707.7K |
| Primo Brands CorporationCL A(PRMB) | 37,500 | 75,000 | +37,500 | $1.11M | $1.66M | 0.06% | +$546.8K |
| Spotify Technology S.A.SHS(SPOT) | 0 | 2,173 | +2,173 | $0 | $1.52M | 0.06% | +$1.52M |
| NIQ Global Intelligence plc(NIQ) | 0 | 95,000 | +95,000 | $0 | $1.49M | 0.06% | +$1.49M |
| monday.com LtdSHS SHS | 0 | 7,000 | +7,000 | $0 | $1.36M | 0.05% | +$1.36M |
| SailPoint, Inc.(SAIL) | 50,000 | 50,000 | 0 | $1.14M | $1.10M | 0.04% | -$39.0K |
| Elastic NV ORD SHS | 0 | 12,500 | +12,500 | $0 | $1.06M | 0.04% | +$1.06M |
| IREN Ltd ORDINARY SHARES | 0 | 20,000 | +20,000 | $0 | $938.1K | 0.04% | +$938.1K |