Securities ▲▼ | Shares | Value ($K) | |||||
|---|---|---|---|---|---|---|---|
Q4 2025 ▲▼ | Q1 2026 ▲▼ | Change ▲▼ | Q4 2025 ▲▼ | Q1 2026 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| ENLIVEN THERAPEUTICS INC | 222,308 | 220,091 | -2,217 | 3,424 | 8,628 | 5.08% | +5,204 |
| INSMED INC(INSM) | 0 | 26,651 | +26,651 | 0 | 4,358 | 2.56% | +4,358 |
| MOONLAKE IMMUNOTHERAPEUTICS(MLTX) | 0 | 215,376 | +215,376 | 0 | 4,015 | 2.36% | +4,015 |
| RHYTHM PHARMACEUTICALS INC(RYTM) | 0 | 40,581 | +40,581 | 0 | 3,529 | 2.08% | +3,529 |
| ALUMIS INC | 292,250 | 279,176 | -13,074 | 2,852 | 6,150 | 3.62% | +3,298 |
| BOSTON SCIENTIFIC CORP(BSX) | 0 | 48,347 | +48,347 | 0 | 3,034 | 1.79% | +3,034 |
| ALKERMES PLC(ALKS) | 0 | 84,103 | +84,103 | 0 | 2,974 | 1.75% | +2,974 |
| MONTE ROSA THERAPEUTICS INC(GLUE) | 0 | 179,484 | +179,484 | 0 | 2,953 | 1.74% | +2,953 |
| CRESCENT BIOPHARMA INC.(CBIO) | 0 | 153,191 | +153,191 | 0 | 2,814 | 1.66% | +2,814 |
| RELAY THERAPEUTICS INC(RLAY) | 0 | 278,302 | +278,302 | 0 | 2,769 | 1.63% | +2,769 |
| MAZE THERAPEUTICS INC(MAZE) | 0 | 88,510 | +88,510 | 0 | 2,642 | 1.55% | +2,642 |
| AVALO THERAPEUTICS INC(AVTX) | 0 | 159,341 | +159,341 | 0 | 2,379 | 1.40% | +2,379 |
| SOLENO THERAPEUTICS INC | 0 | 61,673 | +61,673 | 0 | 2,065 | 1.21% | +2,065 |
| ZENAS BIOPHARMA INC(ZBIO) | 0 | 80,730 | +80,730 | 0 | 1,578 | 0.93% | +1,578 |
| UNITEDHEALTH GROUP INC(UNH) | 5,835 | 12,862 | +7,027 | 1,926 | 3,480 | 2.05% | +1,554 |
| 4D MOLECULAR THERAPEUTICS IN | 0 | 130,564 | +130,564 | 0 | 1,216 | 0.72% | +1,216 |
| CORBUS PHARMACEUTICALS HLDGS(CRBP) | 139,543 | 234,136 | +94,593 | 1,136 | 2,199 | 1.29% | +1,063 |
| ADAGENE INC | 1,060,221 | 736,845 | -323,376 | 2,004 | 2,888 | 1.70% | +885 |
| 10X GENOMICS INC(TXG) | 163,658 | 154,194 | -9,464 | 2,669 | 3,274 | 1.93% | +604 |
| AGIOS PHARMACEUTICALS INC(AGIO) | 136,942 | 125,060 | -11,882 | 3,728 | 4,231 | 2.49% | +503 |
| LIPOCINE INC NEW(LPCN) | 0 | 60,861 | +60,861 | 0 | 486 | 0.29% | +486 |
| UNITED THERAPEUTICS CORP DEL(UTHR) | 7,685 | 7,053 | -632 | 3,745 | 4,182 | 2.46% | +438 |
| VERASTEM INC(VSTM) | 401,743 | 636,700 | +234,957 | 3,101 | 3,375 | 1.99% | +273 |
| APELLIS PHARMACEUTICALS INC COM | 135,849 | 85,517 | -50,332 | 3,413 | 3,440 | 2.02% | +28 |
| ARBUTUS BIOPHARMA CORP(ABUS) | 75,484 | 75,484 | 0 | 363 | 340 | 0.20% | -23 |
| COGENT BIOSCIENCES INC(COGT) | 305,568 | 278,533 | -27,035 | 10,854 | 10,721 | 6.31% | -133 |
| ESTABLISHMENT LABS HLDGS INC(ESTA) | 13,100 | 13,100 | 0 | 955 | 744 | 0.44% | -211 |
| ARROWHEAD PHARMACEUTICALS IN(ARWR) | 49,758 | 45,721 | -4,037 | 3,303 | 2,867 | 1.69% | -437 |
| RAPT THERAPEUTICS INC | 14,194 | 0 | -14,194 | 481 | 0 | — | -481 |
| NATERA INC(NTRA) | 18,650 | 18,650 | 0 | 4,273 | 3,730 | 2.19% | -543 |
| NOVABRIDGE BIOSCIENCES(NBP) | 499,587 | 576,960 | +77,373 | 1,988 | 1,419 | 0.84% | -569 |
| INTUITIVE SURGICAL INC | 6,358 | 6,358 | 0 | 3,601 | 2,931 | 1.72% | -670 |
| CYTOMX THERAPEUTICS INC.(CTMX) | 745,305 | 521,468 | -223,837 | 3,175 | 2,451 | 1.44% | -724 |
| PENUMBRA INC(PEN) | 9,000 | 6,300 | -2,700 | 2,798 | 2,069 | 1.22% | -729 |
| PALISADE BIO INC(PALI) | 758,203 | 600,000 | -158,203 | 1,782 | 1,050 | 0.62% | -732 |
| IONIS PHARMACEUTICALS INC(IONS) | 116,515 | 110,064 | -6,451 | 9,218 | 8,265 | 4.86% | -953 |
| FULCRUM THERAPEUTICS INC(FULC) | 92,055 | 0 | -92,055 | 1,041 | 0 | — | -1,041 |
| CYTOKINETICS INC(CYTK) | 124,749 | 103,718 | -21,031 | 7,927 | 6,836 | 4.02% | -1,090 |
| NEXTCURE INC | 165,000 | 115,500 | -49,500 | 2,341 | 1,215 | 0.71% | -1,126 |
| BRIDGEBIO PHARMA INC(BBIO) | 80,723 | 67,492 | -13,231 | 6,175 | 5,012 | 2.95% | -1,163 |
| TENET HEALTHCARE CORP(THC) | 6,084 | 0 | -6,084 | 1,209 | 0 | — | -1,209 |
| IQVIA HLDGS INC(IQV) | 5,378 | 0 | -5,378 | 1,212 | 0 | — | -1,212 |
| INHIBIKASE THERAPEUTICS INC(IKT) | 600,000 | 0 | -600,000 | 1,230 | 0 | — | -1,230 |
| GLAUKOS CORP(GKOS) | 31,471 | 20,874 | -10,597 | 3,553 | 2,247 | 1.32% | -1,306 |
| GOSSAMER BIO INC(GOSS) | 451,699 | 0 | -451,699 | 1,400 | 0 | — | -1,400 |
| LIQUIDIA CORPORATION(LQDA) | 91,148 | 45,796 | -45,352 | 3,144 | 1,728 | 1.02% | -1,415 |
| VERA THERAPEUTICS INC(VERA) | 124,391 | 114,991 | -9,400 | 6,299 | 4,626 | 2.72% | -1,673 |
| ELEVANCE HEALTH INC FORMERLY(ELV) | 17,191 | 14,677 | -2,514 | 6,026 | 4,297 | 2.53% | -1,730 |
| UPSTREAM BIO INC(UPB) | 64,845 | 0 | -64,845 | 1,761 | 0 | — | -1,761 |
| ELI LILLY & CO(LLY) | 7,852 | 7,012 | -840 | 8,438 | 6,449 | 3.79% | -1,989 |
| KARYOPHARM THERAPEUTICS INC(KPTI) | 295,541 | 0 | -295,541 | 2,175 | 0 | — | -2,175 |
| IRONWOOD PHARMACEUTICALS INC(IRWD) | 648,532 | 0 | -648,532 | 2,186 | 0 | — | -2,186 |
| WAYSTAR HLDG CORP(WAY) | 68,969 | 0 | -68,969 | 2,259 | 0 | — | -2,259 |
| BELITE BIO INC(BLTE) | 14,328 | 0 | -14,328 | 2,292 | 0 | — | -2,292 |
| GUARDANT HEALTH INC(GH) | 98,182 | 82,736 | -15,446 | 10,028 | 7,642 | 4.50% | -2,386 |
| PRAXIS PRECISION MEDICINES I(PRAX) | 58,122 | 45,469 | -12,653 | 17,131 | 14,650 | 8.62% | -2,481 |
| EDGEWISE THERAPEUTICS INC(EWTX) | 100,046 | 0 | -100,046 | 2,483 | 0 | — | -2,483 |
| IMMUNOCORE HLDGS PLC(IMCR) | 76,750 | 0 | -76,750 | 2,664 | 0 | — | -2,664 |
| DEXCOM INC(DXCM) | 50,147 | 0 | -50,147 | 3,328 | 0 | — | -3,328 |
| TRAVERE THERAPEUTICS INC(TVTX) | 89,052 | 0 | -89,052 | 3,403 | 0 | — | -3,403 |
| CELCUITY INC(CELC) | 34,289 | 0 | -34,289 | 3,420 | 0 | — | -3,420 |
| DISC MEDICINE INC(IRON) | 46,743 | 0 | -46,743 | 3,712 | 0 | — | -3,712 |
| UNIVERSAL HLTH SVCS INC(UHS) | 17,628 | 0 | -17,628 | 3,843 | 0 | — | -3,843 |
| IMMUNOVANT INC(IMVT) | 158,622 | 0 | -158,622 | 4,032 | 0 | — | -4,032 |
| JAZZ PHARMACEUTICALS PLC(JAZZ) | 26,494 | 0 | -26,494 | 4,504 | 0 | — | -4,504 |
| ASTRAZENECA PLC(AZN) | 28,362 | 0 | -28,362 | 5,261 | 0 | — | -5,261 |
| WAVE LIFE SCIENCES LTD(WVE) | 421,488 | 0 | -421,488 | 7,165 | 0 | — | -7,165 |