DIADEMA PARTNERS LP
Securities ▲▼ | Shares | Value ($K) | |||||
|---|---|---|---|---|---|---|---|
Q4 2025 ▲▼ | Q1 2026 ▲▼ | Change ▲▼ | Q4 2025 ▲▼ | Q1 2026 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| LIQUIDIA CORPORATION(LQDA)(Call) | 0 | 662,100 | +662,100 | 0 | 24,987,654 | — | +24,987,654 |
| UNITED THERAPEUTICS CORP DEL(UTHR)(Call) | 0 | 40,200 | +40,200 | 0 | 23,837,796 | — | +23,837,796 |
| BRIDGEBIO PHARMA INC(BBIO) | 0 | 250,000 | +250,000 | 0 | 18,565,000 | 7.67% | +18,565,000 |
| CYTOKINETICS INC(CYTK)(Put) | 0 | 200,000 | +200,000 | 0 | 13,182,000 | — | +13,182,000 |
| CAPRICOR THERAPEUTICS INC(CAPR)(Put) | 200,000 | 623,400 | +423,400 | 5,772,000 | 18,951,360 | — | +13,179,360 |
| REVOLUTION MEDICINES INC(RVMD)(Put) | 0 | 125,500 | +125,500 | 0 | 12,204,875 | — | +12,204,875 |
| MERCK & CO INC(MRK)(Put) | 0 | 100,000 | +100,000 | 0 | 12,029,000 | — | +12,029,000 |
| UNITED THERAPEUTICS CORP DEL(UTHR)(Put) | 0 | 20,000 | +20,000 | 0 | 11,859,600 | — | +11,859,600 |
| UNITED THERAPEUTICS CORP DEL(UTHR) | 10,000 | 27,303 | +17,303 | 4,872,500 | 16,190,133 | 6.69% | +11,317,633 |
| ABIVAX SA(ABVX)(Put) | 0 | 100,000 | +100,000 | 0 | 11,135,000 | — | +11,135,000 |
| ABIVAX SA(ABVX)(Call) | 0 | 100,000 | +100,000 | 0 | 11,135,000 | — | +11,135,000 |
| JAZZ PHARMACEUTICALS PLC(JAZZ) | 0 | 54,755 | +54,755 | 0 | 10,351,433 | 4.27% | +10,351,433 |
| KODIAK SCIENCES INC(KOD)(Put) | 0 | 246,900 | +246,900 | 0 | 9,411,828 | — | +9,411,828 |
| MODERNA INC(MRNA)(Put) | 0 | 159,400 | +159,400 | 0 | 8,097,520 | — | +8,097,520 |
| COGENT BIOSCIENCES INC(COGT) | 131,852 | 322,764 | +190,912 | 4,683,383 | 12,423,186 | 5.13% | +7,739,803 |
| KODIAK SCIENCES INC(KOD) | 0 | 192,962 | +192,962 | 0 | 7,355,711 | 3.04% | +7,355,711 |
| INCYTE CORP(INCY) | 0 | 78,029 | +78,029 | 0 | 7,344,089 | 3.03% | +7,344,089 |
| EDGEWISE THERAPEUTICS INC(EWTX)(Call) | 0 | 212,500 | +212,500 | 0 | 6,693,750 | — | +6,693,750 |
| CORCEPT THERAPEUTICS INC(CORT)(Call) | 0 | 158,500 | +158,500 | 0 | 6,389,135 | — | +6,389,135 |
| STRUCTURE THERAPEUTICS INC(Put) | 0 | 127,500 | +127,500 | 0 | 6,145,500 | — | +6,145,500 |
| VIKING THERAPEUTICS INC(VKTX) | 336,849 | 525,181 | +188,332 | 11,850,348 | 17,089,390 | 7.06% | +5,239,042 |
| ABBVIE INC(ABBV) | 0 | 24,058 | +24,058 | 0 | 5,232,374 | 2.16% | +5,232,374 |
| ARCUS BIOSCIENCES INC(RCUS) | 0 | 238,142 | +238,142 | 0 | 5,143,867 | 2.12% | +5,143,867 |
| REVOLUTION MEDICINES INC(RVMD) | 37,020 | 80,872 | +43,852 | 2,948,643 | 7,864,802 | 3.25% | +4,916,159 |
| CORBUS PHARMACEUTICALS HLDGS | 0 | 439,957 | +439,957 | 0 | 4,131,196 | 1.71% | +4,131,196 |
| UNIQURE NV(QURE)(Call) | 0 | 250,000 | +250,000 | 0 | 4,087,500 | — | +4,087,500 |
| CORVUS PHARMACEUTICALS INC(CRVS) | 0 | 244,811 | +244,811 | 0 | 3,581,585 | 1.48% | +3,581,585 |
| ZYMEWORKS INC(ZYME) | 0 | 142,132 | +142,132 | 0 | 3,558,985 | 1.47% | +3,558,985 |
| REPLIMUNE GROUP INC(REPL)(Put) | 0 | 459,900 | +459,900 | 0 | 3,518,235 | — | +3,518,235 |
| STRUCTURE THERAPEUTICS INC | 0 | 72,234 | +72,234 | 0 | 3,481,679 | 1.44% | +3,481,679 |
| IMMUNOCORE HLDGS PLC(IMCR) | 70,300 | 193,189 | +122,889 | 2,440,113 | 5,824,648 | 2.41% | +3,384,535 |
| ELI LILLY & CO(LLY) | 2,000 | 6,000 | +4,000 | 2,149,360 | 5,518,620 | 2.28% | +3,369,260 |
| CYTOKINETICS INC(CYTK)(Call) | 0 | 50,000 | +50,000 | 0 | 3,295,500 | — | +3,295,500 |
| TG THERAPEUTICS INC(TGTX) | 123,283 | 206,928 | +83,645 | 3,675,066 | 6,874,148 | 2.84% | +3,199,082 |
| VAXCYTE INC(PCVX)(Call) | 0 | 53,100 | +53,100 | 0 | 3,085,641 | — | +3,085,641 |
| APOGEE THERAPEUTICS INC(APGE)(Call) | 211,100 | 222,500 | +11,400 | 15,933,828 | 18,727,825 | — | +2,793,997 |
| ROIVANT SCIENCES LTD(ROIV)(Put) | 318,700 | 335,800 | +17,100 | 6,915,790 | 9,301,660 | — | +2,385,870 |
| HARMONY BIOSCIENCES HLDGS IN(HRMY) | 7,500 | 92,864 | +85,364 | 280,650 | 2,601,121 | 1.07% | +2,320,471 |
| EYEPOINT INC(EYPT) | 0 | 178,545 | +178,545 | 0 | 2,301,445 | 0.95% | +2,301,445 |
| BICYCLE THERAPEUTICS PLC | 0 | 476,424 | +476,424 | 0 | 2,210,607 | 0.91% | +2,210,607 |
| ALUMIS INC(Call) | 0 | 100,000 | +100,000 | 0 | 2,203,000 | — | +2,203,000 |
| INDIVIOR PHARMACEUTICALS INC(INDV) | 0 | 71,376 | +71,376 | 0 | 2,175,540 | 0.90% | +2,175,540 |
| MONTE ROSA THERAPEUTICS INC(GLUE) | 62,281 | 187,307 | +125,026 | 976,566 | 3,081,200 | 1.27% | +2,104,634 |
| CELCUITY INC(CELC)(Call) | 0 | 17,700 | +17,700 | 0 | 2,020,278 | — | +2,020,278 |
| CLIMB BIO INC | 0 | 286,126 | +286,126 | 0 | 1,959,963 | 0.81% | +1,959,963 |
| SHATTUCK LABS INC | 0 | 293,664 | +293,664 | 0 | 1,888,260 | 0.78% | +1,888,260 |
| LIQUIDIA CORPORATION(LQDA)(Put) | 0 | 50,000 | +50,000 | 0 | 1,887,000 | — | +1,887,000 |
| TARSUS PHARMACEUTICALS INC(TARS) | 0 | 25,942 | +25,942 | 0 | 1,819,831 | 0.75% | +1,819,831 |
| ALKERMES PLC(ALKS) | 0 | 50,000 | +50,000 | 0 | 1,768,000 | 0.73% | +1,768,000 |
| MACROGENICS INC | 0 | 600,000 | +600,000 | 0 | 1,734,000 | 0.72% | +1,734,000 |
| VOYAGER THERAPEUTICS INC | 0 | 423,642 | +423,642 | 0 | 1,635,258 | 0.68% | +1,635,258 |
| REPLIMUNE GROUP INC(REPL)(Call) | 0 | 205,500 | +205,500 | 0 | 1,572,075 | — | +1,572,075 |
| CORVUS PHARMACEUTICALS INC(CRVS)(Call) | 0 | 106,300 | +106,300 | 0 | 1,555,169 | — | +1,555,169 |
| VERTEX PHARMACEUTICALS INC(VRTX)(Call) | 88,300 | 93,100 | +4,800 | 40,031,688 | 41,572,874 | — | +1,541,186 |
| CYTOMX THERAPEUTICS INC.(Call) | 0 | 316,000 | +316,000 | 0 | 1,485,200 | — | +1,485,200 |
| EYEPOINT INC(EYPT)(Call) | 0 | 106,300 | +106,300 | 0 | 1,370,207 | — | +1,370,207 |
| KARYOPHARM THERAPEUTICS INC(Call) | 0 | 241,300 | +241,300 | 0 | 1,344,041 | — | +1,344,041 |
| CORBUS PHARMACEUTICALS HLDGS(Call) | 0 | 115,300 | +115,300 | 0 | 1,082,667 | — | +1,082,667 |
| IOVANCE BIOTHERAPEUTICS INC(IOVA)(Call) | 0 | 300,000 | +300,000 | 0 | 1,053,000 | — | +1,053,000 |
| CAPRICOR THERAPEUTICS INC(CAPR)(Call) | 312,300 | 329,300 | +17,000 | 9,012,978 | 10,010,720 | — | +997,742 |
| BRIDGEBIO PHARMA INC(BBIO) | 70,000 | 85,311 | +15,311 | 5,354,300 | 6,335,195 | 2.62% | +980,895 |
| ANAVEX LIFE SCIENCES CORP(Call) | 140,600 | 477,600 | +337,000 | 500,536 | 1,466,232 | — | +965,696 |
| DIANTHUS THERAPEUTICS INC(DNTH) | 0 | 10,000 | +10,000 | 0 | 839,200 | 0.35% | +839,200 |
| PHARVARIS N V COM | 0 | 29,321 | +29,321 | 0 | 828,318 | 0.34% | +828,318 |
| IMMUNITYBIO INC(IBRX)(Put) | 0 | 106,300 | +106,300 | 0 | 815,321 | — | +815,321 |
| LARIMAR THERAPEUTICS INC | 0 | 166,637 | +166,637 | 0 | 749,867 | 0.31% | +749,867 |
| ULTRAGENYX PHARMACEUTICAL IN(RARE) | 0 | 35,144 | +35,144 | 0 | 736,267 | 0.30% | +736,267 |
| UNICYCIVE THERAPEUTICS INC | 0 | 106,083 | +106,083 | 0 | 698,026 | 0.29% | +698,026 |
| ALUMIS INC(Put) | 0 | 31,200 | +31,200 | 0 | 687,336 | — | +687,336 |
| INTELLIA THERAPEUTICS INC(NTLA)(Call) | 212,400 | 200,000 | -12,400 | 1,909,476 | 2,564,000 | — | +654,524 |
| SPRUCE BIOSCIENCES INC | 0 | 10,000 | +10,000 | 0 | 653,500 | 0.27% | +653,500 |
| PHATHOM PHARMACEUTICALS INC(PHAT) | 0 | 54,650 | +54,650 | 0 | 607,162 | 0.25% | +607,162 |
| CELCUITY INC(CELC) | 0 | 5,314 | +5,314 | 0 | 606,540 | 0.25% | +606,540 |
| VOYAGER THERAPEUTICS INC(Call) | 0 | 150,000 | +150,000 | 0 | 579,000 | — | +579,000 |
| OCUGEN INC(Call) | 0 | 300,000 | +300,000 | 0 | 543,000 | — | +543,000 |
| CONNECT BIOPHARMA HLDGS LTD | 0 | 200,690 | +200,690 | 0 | 525,808 | 0.22% | +525,808 |
| NOVO-NORDISK A S(NVO) | 0 | 14,577 | +14,577 | 0 | 520,736 | 0.22% | +520,736 |
| MAZE THERAPEUTICS INC(MAZE) | 0 | 15,000 | +15,000 | 0 | 447,750 | 0.18% | +447,750 |
| BIOHAVEN LTD(BHVN)(Call) | 200,000 | 317,000 | +117,000 | 2,258,000 | 2,681,820 | — | +423,820 |
| ANNEXON INC(ANNX)(Call) | 309,100 | 353,200 | +44,100 | 1,551,682 | 1,956,728 | — | +405,046 |
| VAXCYTE INC(PCVX) | 22,972 | 25,071 | +2,099 | 1,059,928 | 1,456,876 | 0.60% | +396,948 |
| INVENTIVA SA(IVA) | 334,251 | 352,399 | +18,148 | 1,554,267 | 1,935,023 | 0.80% | +380,756 |
| GH RESEARCH PLC(GHRS) | 0 | 26,836 | +26,836 | 0 | 377,314 | 0.16% | +377,314 |
| OCUGEN INC | 0 | 200,000 | +200,000 | 0 | 362,000 | 0.15% | +362,000 |
| EQUILLIUM INC | 347,393 | 433,844 | +86,451 | 538,459 | 867,688 | 0.36% | +329,229 |
| EUPRAXIA PHARMACEUTICALS INC | 0 | 40,000 | +40,000 | 0 | 289,600 | 0.12% | +289,600 |
| PEPGEN INC | 0 | 150,925 | +150,925 | 0 | 267,137 | 0.11% | +267,137 |
| VIR BIOTECHNOLOGY INC(VIR)(Call) | 89,200 | 88,800 | -400 | 537,876 | 795,648 | — | +257,772 |
| FOGHORN THERAPEUTICS INC | 30,630 | 79,944 | +49,314 | 165,402 | 382,132 | 0.16% | +216,730 |
| PRECIGEN INC(PGEN) | 0 | 55,293 | +55,293 | 0 | 213,984 | 0.09% | +213,984 |
| COMPASS PATHWAYS PLC(CMPS) | 0 | 31,885 | +31,885 | 0 | 176,324 | 0.07% | +176,324 |
| AYTU BIOPHARMA INC | 305,788 | 353,077 | +47,289 | 795,049 | 963,900 | 0.40% | +168,851 |
| PASSAGE BIO INC | 0 | 19,530 | +19,530 | 0 | 153,311 | 0.06% | +153,311 |
| ROCKET PHARMACEUTICALS INC | 0 | 30,579 | +30,579 | 0 | 109,473 | 0.05% | +109,473 |
| MONOPAR THERAPEUTICS INC | 0 | 1,630 | +1,630 | 0 | 89,308 | 0.04% | +89,308 |
| INOVIO PHARMACEUTICALS INC | 533,682 | 562,665 | +28,983 | 928,607 | 979,037 | 0.40% | +50,430 |
| INCYTE CORP(INCY)(Put) | 100,000 | 105,400 | +5,400 | 9,877,000 | 9,920,248 | — | +43,248 |
| ATRIUM THERAPEUTICS INC | 0 | 2,512 | +2,512 | 0 | 33,585 | 0.01% | +33,585 |
| CUE BIOPHARMA INC | 0 | 131,997 | +131,997 | 0 | 30,346 | 0.01% | +30,346 |
| ENTERA BIO LTD | 0 | 23,260 | +23,260 | 0 | 25,819 | 0.01% | +25,819 |