Securities ▲▼ | Shares | Value ($K) | |||||
|---|---|---|---|---|---|---|---|
Q1 2025 ▲▼ | Q2 2025 ▲▼ | Change ▲▼ | Q1 2025 ▲▼ | Q2 2025 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| SOLENO THERAPEUTICS INC | 93,002 | 284,152 | +191,150 | 6,645 | 23,806 | 14.80% | +17,161 |
| AMGEN INC(AMGN) | 0 | 52,100 | +52,100 | 0 | 14,547 | 9.04% | +14,547 |
| BIOMARIN PHARMACEUTICAL INC(BMRN) | 52,877 | 192,877 | +140,000 | 3,738 | 10,602 | 6.59% | +6,865 |
| TG THERAPEUTICS INC(TGTX) | 207,883 | 371,448 | +163,565 | 8,197 | 13,368 | 8.31% | +5,172 |
| NEUROCRINE BIOSCIENCES INC(NBIX) | 62,247 | 94,042 | +31,795 | 6,885 | 11,820 | 7.35% | +4,936 |
| VERTEX PHARMACEUTICALS INC(VRTX) | 0 | 10,000 | +10,000 | 0 | 4,452 | 2.77% | +4,452 |
| PROTAGONIST THERAPEUTICS INC | 0 | 76,185 | +76,185 | 0 | 4,211 | 2.62% | +4,211 |
| GILEAD SCIENCES INC(GILD) | 0 | 30,000 | +30,000 | 0 | 3,326 | 2.07% | +3,326 |
| VAXCYTE INC(PCVX) | 92,385 | 198,285 | +105,900 | 3,488 | 6,446 | 4.01% | +2,958 |
| REVOLUTION MEDICINES INC(RVMD) | 0 | 79,079 | +79,079 | 0 | 2,909 | 1.81% | +2,909 |
| VIKING THERAPEUTICS INC(VKTX) | 104,121 | 197,468 | +93,347 | 2,515 | 5,233 | 3.25% | +2,718 |
| ITEOS THERAPEUTICS INC | 0 | 206,200 | +206,200 | 0 | 2,056 | 1.28% | +2,056 |
| ULTRAGENYX PHARMACEUTICAL IN(RARE) | 0 | 53,985 | +53,985 | 0 | 1,963 | 1.22% | +1,963 |
| MERCK & CO INC(MRK) | 0 | 20,000 | +20,000 | 0 | 1,583 | 0.98% | +1,583 |
| UROGEN PHARMA LTD(URGN) | 76,220 | 150,000 | +73,780 | 843 | 2,055 | 1.28% | +1,212 |
| MIND MEDICINE MINDMED INC | 0 | 158,536 | +158,536 | 0 | 1,029 | 0.64% | +1,029 |
| SCPHARMACEUTICALS INC | 0 | 217,623 | +217,623 | 0 | 829 | 0.52% | +829 |
| TERNS PHARMACEUTICALS INC | 56,098 | 259,852 | +203,754 | 155 | 969 | 0.60% | +814 |
| ARVINAS INC(ARVN) | 0 | 96,455 | +96,455 | 0 | 710 | 0.44% | +710 |
| OLEMA PHARMACEUTICALS INC(OLMA) | 100,000 | 253,657 | +153,657 | 376 | 1,081 | 0.67% | +705 |
| COGENT BIOSCIENCES INC(COGT) | 392,213 | 392,213 | 0 | 2,349 | 2,816 | 1.75% | +467 |
| PACIRA BIOSCIENCES INC(PCRX) | 38,926 | 58,926 | +20,000 | 967 | 1,408 | 0.88% | +441 |
| REVIVA PHARMACEUTCLS HLDGS I | 650,723 | 2,735,457 | +2,084,734 | 621 | 1,042 | 0.65% | +422 |
| IMMUNOCORE HLDGS PLC(IMCR) | 96,984 | 104,384 | +7,400 | 2,878 | 3,276 | 2.04% | +398 |
| PHATHOM PHARMACEUTICALS INC(PHAT) | 0 | 40,294 | +40,294 | 0 | 386 | 0.24% | +386 |
| NUVALENT INC | 0 | 5,000 | +5,000 | 0 | 382 | 0.24% | +382 |
| SCHOLAR ROCK HLDG CORP(SRRK) | 57,923 | 62,926 | +5,003 | 1,862 | 2,229 | 1.39% | +367 |
| JAZZ PHARMACEUTICALS PLC(JAZZ) | 87,189 | 104,473 | +17,284 | 10,825 | 11,087 | 6.89% | +262 |
| ELEVATION ONCOLOGY INC | 0 | 362,935 | +362,935 | 0 | 133 | 0.08% | +133 |
| PURETECH HEALTH PLC(PRTCY) | 0 | 7,324 | +7,324 | 0 | 126 | 0.08% | +126 |
| CLIMB BIO INC(CLYM) | 669,803 | 702,135 | +32,332 | 817 | 871 | 0.54% | +53 |
| PROQR THRAPEUTICS N V SHS EURO | 207,694 | 157,694 | -50,000 | 276 | 322 | 0.20% | +45 |
| SUMMIT THERAPEUTICS INC(SMMT) | 0 | 932 | +932 | 0 | 20 | 0.01% | +20 |
| ZAI LAB LTD(ZLAB) | 0 | 3,785 | +3,785 | 0 | 13 | 0.01% | +13 |
| ELEDON PHARMACEUTICALS INC(ELDN) | 64,613 | 64,613 | 0 | 219 | 175 | 0.11% | -44 |
| TREVI THERAPEUTICS INC(TRVI) | 180,000 | 185,830 | +5,830 | 1,132 | 1,016 | 0.63% | -116 |
| CANDEL THERAPEUTICS INC(CADL) | 25,045 | 0 | -25,045 | 142 | 0 | — | -142 |
| SAGIMET BIOSCIENCES INC(SGMT) | 46,019 | 0 | -46,019 | 150 | 0 | — | -150 |
| MEREO BIOPHARMA GROUP PLC(MREO) | 492,215 | 0 | -492,215 | 169 | 0 | — | -169 |
| ALECTOR INC | 456,546 | 266,023 | -190,523 | 562 | 372 | 0.23% | -189 |
| GOSSAMER BIO INC(GOSS) | 269,589 | 0 | -269,589 | 297 | 0 | — | -297 |
| UNIQURE NV(QURE) | 36,500 | 0 | -36,500 | 387 | 0 | — | -387 |
| REPLIMUNE GROUP INC(REPL) | 74,530 | 32,483 | -42,047 | 727 | 302 | 0.19% | -425 |
| VIRIDIAN THERAPEUTICS INC(VRDN) | 162,063 | 122,061 | -40,002 | 2,185 | 1,706 | 1.06% | -478 |
| VISTAGEN THERAPEUTICS INC(VTGN) | 565,975 | 403,922 | -162,053 | 1,415 | 808 | 0.50% | -607 |
| 89BIO INC | 231,436 | 98,382 | -133,054 | 1,683 | 966 | 0.60% | -716 |
| CYTOKINETICS INC(CYTK) | 20,000 | 0 | -20,000 | 804 | 0 | — | -804 |
| RELAY THERAPEUTICS INC(RLAY) | 426,346 | 43,616 | -382,730 | 1,117 | 151 | 0.09% | -966 |
| APOGEE THERAPEUTICS INC(APGE) | 40,000 | 10,572 | -29,428 | 1,494 | 459 | 0.29% | -1,035 |
| ASCENDIS PHARMA A/S(ASND) | 8,321 | 0 | -8,321 | 1,297 | 0 | — | -1,297 |
| SAGE THERAPEUTICS INC | 183,466 | 0 | -183,466 | 1,459 | 0 | — | -1,459 |
| KALVISTA PHARMACEUTICALS INC | 135,509 | 0 | -135,509 | 1,564 | 0 | — | -1,564 |
| NOVO-NORDISK A S(NVO) | 24,618 | 0 | -24,618 | 1,676 | 0 | — | -1,676 |
| CENTESSA PHARMACEUTICALS PLC | 164,048 | 0 | -164,048 | 2,359 | 0 | — | -2,359 |
| SPRINGWORKS THERAPEUTICS INC | 60,000 | 0 | -60,000 | 2,648 | 0 | — | -2,648 |
| RHYTHM PHARMACEUTICALS INC(RYTM) | 50,000 | 0 | -50,000 | 2,649 | 0 | — | -2,648 |
| ALNYLAM PHARMACEUTICALS INC(ALNY) | 13,115 | 0 | -13,115 | 3,541 | 0 | — | -3,541 |
| ARGENX SE(ARGX) | 12,279 | 5,974 | -6,305 | 7,179 | 3,293 | 2.05% | -3,886 |
| ELI LILLY & CO(LLY) | 19,302 | 14,816 | -4,486 | 15,942 | 11,550 | 7.18% | -4,392 |
| REGENERON PHARMACEUTICALS(REGN) | 29,828 | 5,607 | -24,221 | 18,918 | 2,944 | 1.83% | -15,974 |