Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q2 2025 ▲▼ | Q3 2025 ▲▼ | Change ▲▼ | Q2 2025 ▲▼ | Q3 2025 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| Regeneron Pharmaceuticals, Inc.(REGN) | 5,607 | 30,160 | +24,553 | $2.94M | $16.96M | 11.81% | +$14.01M |
| Soleno Therapeutics Inc | 284,152 | 177,330 | -106,822 | $23.81M | $11.99M | 8.35% | -$11.82M |
| BioMarin Pharmaceutical Inc.(BMRN) | 192,877 | 212,877 | +20,000 | $10.60M | $11.53M | 8.03% | +$927.0K |
| Vaxcyte, Inc.(PCVX) | 198,285 | 218,285 | +20,000 | $6.45M | $7.86M | 5.48% | +$1.42M |
| Indivior Plc | 0 | 254,252 | +254,252 | $0 | $6.13M | 4.27% | +$6.13M |
| Bristol-Myers Squibb Company(BMY) | 0 | 130,000 | +130,000 | $0 | $5.86M | 4.08% | +$5.86M |
| Ascendis Pharma A/SADR(ASND) | 0 | 27,572 | +27,572 | $0 | $5.48M | 3.82% | +$5.48M |
| Neurocrine Biosciences, Inc.(NBIX) | 94,042 | 37,754 | -56,288 | $11.82M | $5.30M | 3.69% | -$6.52M |
| Viking Therapeutics, Inc.(VKTX) | 197,468 | 193,689 | -3,779 | $5.23M | $5.09M | 3.55% | -$142.8K |
| Alnylam Pharmaceuticals, Inc.(ALNY) | 0 | 10,000 | +10,000 | $0 | $4.56M | 3.18% | +$4.56M |
| Immunocore Holdings plcADS(IMCR) | 104,384 | 124,384 | +20,000 | $3.28M | $4.52M | 3.15% | +$1.24M |
| Nektar Therapeutics(NKTR) | 0 | 75,000 | +75,000 | $0 | $4.27M | 2.97% | +$4.27M |
| ABIVAX Société AnonymeADS(ABVX) | 0 | 41,620 | +41,620 | $0 | $3.51M | 2.45% | +$3.51M |
| Protagonist Therapeutics Inc | 76,185 | 51,185 | -25,000 | $4.21M | $3.40M | 2.37% | -$810.5K |
| Jazz Pharmaceuticals plcSHS USD(JAZZ) | 104,473 | 23,140 | -81,333 | $11.09M | $3.05M | 2.12% | -$8.04M |
| ANI Pharmaceuticals, Inc.(ANIP) | 0 | 31,400 | +31,400 | $0 | $2.88M | 2.00% | +$2.88M |
| Revolution Medicines, Inc.(RVMD) | 79,079 | 59,079 | -20,000 | $2.91M | $2.76M | 1.92% | -$150.3K |
| Apogee Therapeutics Inc | 10,572 | 64,250 | +53,678 | $459.1K | $2.55M | 1.78% | +$2.09M |
| Terns Pharmaceuticals Inc | 259,852 | 323,159 | +63,307 | $969.2K | $2.43M | 1.69% | +$1.46M |
| Ardelyx Inc | 0 | 400,000 | +400,000 | $0 | $2.20M | 1.54% | +$2.20M |
| TG Therapeutics, Inc.(TGTX) | 371,448 | 60,748 | -310,700 | $13.37M | $2.19M | 1.53% | -$11.17M |
| Alkermes plcSHS(ALKS) | 0 | 72,079 | +72,079 | $0 | $2.16M | 1.51% | +$2.16M |
| Roivant Sciences Ltd.SHS(ROIV) | 0 | 120,000 | +120,000 | $0 | $1.82M | 1.26% | +$1.82M |
| UroGen Pharma Ltd.(URGN) | 150,000 | 90,000 | -60,000 | $2.06M | $1.80M | 1.25% | -$259.5K |
| Pacira BioSciences, Inc.(PCRX) | 58,926 | 58,926 | 0 | $1.41M | $1.52M | 1.06% | +$110.2K |
| Cogent Biosciences, Inc.(COGT) | 392,213 | 97,813 | -294,400 | $2.82M | $1.40M | 0.98% | -$1.41M |
| Novo Nordisk A/SADR(NVO) | 0 | 25,000 | +25,000 | $0 | $1.39M | 0.97% | +$1.39M |
| Harmony Biosciences Holdings, Inc.(HRMY) | 0 | 50,000 | +50,000 | $0 | $1.38M | 0.96% | +$1.38M |
| Amylyx Pharmaceuticals, Inc.(AMLX) | 0 | 100,000 | +100,000 | $0 | $1.36M | 0.95% | +$1.36M |
| Avidity Biosciences Inc | 0 | 30,000 | +30,000 | $0 | $1.31M | 0.91% | +$1.31M |
| Mind Medicine Mindmed Inc | 158,536 | 105,891 | -52,645 | $1.03M | $1.25M | 0.87% | +$219.6K |
| Vistagen Therapeutics, Inc.(VTGN) | 403,922 | 349,789 | -54,133 | $807.8K | $1.24M | 0.86% | +$433.9K |
| MannKind Corporation(MNKD) | 0 | 212,475 | +212,475 | $0 | $1.14M | 0.79% | +$1.14M |
| Supernus Pharmaceuticals, Inc.(SUPN) | 0 | 22,348 | +22,348 | $0 | $1.07M | 0.74% | +$1.07M |
| Catalyst Pharmaceuticals Inc | 0 | 50,000 | +50,000 | $0 | $985.0K | 0.69% | +$985.0K |
| Reviva Pharmaceutcls Hldgs I | 2,735,457 | 2,506,921 | -228,536 | $1.04M | $924.1K | 0.64% | -$118.4K |
| Arcturus Therapeutics Holdings Inc.(ARCT) | 0 | 48,811 | +48,811 | $0 | $899.6K | 0.63% | +$899.6K |
| Trevi Therapeutics, Inc.(TRVI) | 185,830 | 85,830 | -100,000 | $1.02M | $785.3K | 0.55% | -$231.1K |
| Xeris Biopharma Holdings Inc | 0 | 74,753 | +74,753 | $0 | $608.5K | 0.42% | +$608.5K |
| CytomX Therapeutics, Inc.(CTMX) | 0 | 185,286 | +185,286 | $0 | $591.1K | 0.41% | +$591.1K |
| Moderna, Inc.(MRNA) | 0 | 20,000 | +20,000 | $0 | $516.6K | 0.36% | +$516.6K |
| Aytu Biopharma Inc | 0 | 272,670 | +272,670 | $0 | $512.6K | 0.36% | +$512.6K |
| Tenaya Therapeutics, Inc.(TNYA) | 0 | 315,519 | +315,519 | $0 | $511.1K | 0.36% | +$511.1K |
| Equillium, Inc.(EQ) | 0 | 300,000 | +300,000 | $0 | $429.0K | 0.30% | +$429.0K |
| Alector Inc | 266,023 | 136,023 | -130,000 | $372.4K | $402.6K | 0.28% | +$30.2K |
| Proqr Thrapeutics N VSHS EURO SHS EURO | 157,694 | 157,694 | 0 | $321.7K | $335.9K | 0.23% | +$14.2K |
| Pyxis Oncology, Inc.(PYXS) | 0 | 150,000 | +150,000 | $0 | $333.0K | 0.23% | +$333.0K |
| Pelthos Therapeutics Inc.(PTHS) | 0 | 10,498 | +10,498 | $0 | $293.9K | 0.20% | +$293.9K |
| Ultragenyx Pharmaceutical Inc.(RARE) | 53,985 | 9,189 | -44,796 | $1.96M | $276.4K | 0.19% | -$1.69M |
| Climb Bio, Inc.(CLYM) | 702,135 | 136,488 | -565,647 | $870.6K | $274.3K | 0.19% | -$596.3K |
| Neuphoria Therapeutics Inc | 0 | 21,452 | +21,452 | $0 | $252.9K | 0.18% | +$252.9K |
| Foghorn Therapeutics Inc.(FHTX) | 0 | 50,000 | +50,000 | $0 | $244.5K | 0.17% | +$244.5K |
| Ovid Therapeutics Inc.(OVID) | 0 | 187,739 | +187,739 | $0 | $244.1K | 0.17% | +$244.1K |
| Relay Therapeutics, Inc.(RLAY) | 43,616 | 43,616 | 0 | $150.9K | $227.7K | 0.16% | +$76.8K |
| Ventyx Biosciences Inc | 0 | 71,204 | +71,204 | $0 | $221.4K | 0.15% | +$221.4K |
| PureTech Health plcADS(PRTCY) | 7,324 | 7,324 | 0 | $126.3K | $135.5K | 0.09% | +$9.2K |
| Anaptysbio Inc | 0 | 3,295 | +3,295 | $0 | $100.9K | 0.07% | +$100.9K |
| Tvardi Therapeutics, Inc.(TVRD) | 0 | 2,185 | +2,185 | $0 | $85.1K | 0.06% | +$85.1K |
| PMV Pharmaceuticals, Inc.(PMVP) | 0 | 11,300 | +11,300 | $0 | $15.8K | 0.01% | +$15.8K |
| 89bio Inc | 98,382 | 0 | -98,382 | $966.1K | $0 | — | -$966.1K |
| Amgen Inc.(AMGN) | 52,100 | 0 | -52,100 | $14.55M | $0 | — | -$14.55M |
| Arvinas, Inc.(ARVN) | 96,455 | 0 | -96,455 | $709.9K | $0 | — | -$709.9K |
| Eledon Pharmaceuticals, Inc.(ELDN) | 64,613 | 0 | -64,613 | $175.1K | $0 | — | -$175.1K |
| Elevation Oncology Inc | 362,935 | 0 | -362,935 | $133.2K | $0 | — | -$133.2K |
| Eli Lilly and Company(LLY) | 14,816 | 0 | -14,816 | $11.55M | $0 | — | -$11.55M |
| Gilead Sciences, Inc.(GILD) | 30,000 | 0 | -30,000 | $3.33M | $0 | — | -$3.33M |
| Iteos Therapeutics Inc | 206,200 | 0 | -206,200 | $2.06M | $0 | — | -$2.06M |
| Merck & Co., Inc.(MRK) | 20,000 | 0 | -20,000 | $1.58M | $0 | — | -$1.58M |
| Nuvalent Inc | 5,000 | 0 | -5,000 | $381.5K | $0 | — | -$381.5K |
| Olema Pharmaceuticals, Inc.(OLMA) | 253,657 | 0 | -253,657 | $1.08M | $0 | — | -$1.08M |
| Phathom Pharmaceuticals, Inc.(PHAT) | 40,294 | 0 | -40,294 | $386.4K | $0 | — | -$386.4K |
| Replimune Group, Inc.(REPL) | 32,483 | 0 | -32,483 | $301.8K | $0 | — | -$301.8K |
| Scholar Rock Holding Corporation(SRRK) | 62,926 | 0 | -62,926 | $2.23M | $0 | — | -$2.23M |
| Summit Therapeutics Inc.(SMMT) | 932 | 0 | -932 | $19.8K | $0 | — | -$19.8K |
| Vertex Pharmaceuticals Incorporated(VRTX) | 10,000 | 0 | -10,000 | $4.45M | $0 | — | -$4.45M |
| Viridian Therapeutics, Inc.(VRDN) | 122,061 | 0 | -122,061 | $1.71M | $0 | — | -$1.71M |
| Zai Lab LimitedADR(ZLAB) | 3,785 | 0 | -3,785 | $13.2K | $0 | — | -$13.2K |
| argenx SEADR(ARGX) | 5,974 | 0 | -5,974 | $3.29M | $0 | — | -$3.29M |
| Scpharmaceuticals Inc | 217,623 | 0 | -217,623 | $829.1K | $0 | — | -$829.1K |