Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q3 2025 ▲▼ | Q4 2025 ▲▼ | Change ▲▼ | Q3 2025 ▲▼ | Q4 2025 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| Terns Pharmaceuticals Inc | 323,159 | 345,880 | +22,721 | $2.43M | $13.97M | 8.32% | +$11.55M |
| Johnson & Johnson(JNJ) | 0 | 66,444 | +66,444 | $0 | $13.75M | 8.19% | +$13.75M |
| Viking Therapeutics, Inc.(VKTX) | 193,689 | 336,849 | +143,160 | $5.09M | $11.85M | 7.06% | +$6.76M |
| ABIVAX Société AnonymeADS(ABVX) | 41,620 | 75,644 | +34,024 | $3.51M | $10.20M | 6.08% | +$6.69M |
| BioMarin Pharmaceutical Inc.(BMRN) | 212,877 | 146,361 | -66,516 | $11.53M | $8.70M | 5.18% | -$2.83M |
| Regeneron Pharmaceuticals, Inc.(REGN) | 30,160 | 10,300 | -19,860 | $16.96M | $7.95M | 4.73% | -$9.01M |
| BridgeBio Pharma, Inc.(BBIO) | 0 | 70,000 | +70,000 | $0 | $5.35M | 3.19% | +$5.35M |
| United Therapeutics Corporation(UTHR) | 0 | 10,000 | +10,000 | $0 | $4.87M | 2.90% | +$4.87M |
| Cogent Biosciences, Inc.(COGT) | 97,813 | 131,852 | +34,039 | $1.40M | $4.68M | 2.79% | +$3.28M |
| Capricor Therapeutics, Inc.(CAPR) | 0 | 158,075 | +158,075 | $0 | $4.56M | 2.72% | +$4.56M |
| Vertex Pharmaceuticals Incorporated(VRTX) | 0 | 10,000 | +10,000 | $0 | $4.53M | 2.70% | +$4.53M |
| ANI Pharmaceuticals, Inc.(ANIP) | 31,400 | 53,354 | +21,954 | $2.88M | $4.21M | 2.51% | +$1.34M |
| TG Therapeutics, Inc.(TGTX) | 60,748 | 123,283 | +62,535 | $2.19M | $3.68M | 2.19% | +$1.48M |
| BioAge Labs, Inc.(BIOA) | 0 | 271,164 | +271,164 | $0 | $3.59M | 2.14% | +$3.59M |
| Corcept Therapeutics Incorporated(CORT) | 0 | 97,445 | +97,445 | $0 | $3.39M | 2.02% | +$3.39M |
| Tenax Therapeutics, Inc.(TENX) | 0 | 243,170 | +243,170 | $0 | $2.96M | 1.77% | +$2.96M |
| Revolution Medicines, Inc.(RVMD) | 59,079 | 37,020 | -22,059 | $2.76M | $2.95M | 1.76% | +$189.7K |
| Immunocore Holdings plcADS(IMCR) | 124,384 | 70,300 | -54,084 | $4.52M | $2.44M | 1.45% | -$2.08M |
| Ironwood Pharmaceuticals, Inc.CL A(IRWD) | 0 | 683,611 | +683,611 | $0 | $2.30M | 1.37% | +$2.30M |
| Centessa Pharmaceuticals PlcADS | 0 | 90,000 | +90,000 | $0 | $2.25M | 1.34% | +$2.25M |
| Replimune Group, Inc.(REPL) | 0 | 230,997 | +230,997 | $0 | $2.25M | 1.34% | +$2.25M |
| Eli Lilly and Company(LLY) | 0 | 2,000 | +2,000 | $0 | $2.15M | 1.28% | +$2.15M |
| Alnylam Pharmaceuticals, Inc.(ALNY) | 10,000 | 5,341 | -4,659 | $4.56M | $2.12M | 1.26% | -$2.44M |
| Lipocine Inc.(LPCN) | 0 | 260,939 | +260,939 | $0 | $2.10M | 1.25% | +$2.10M |
| Protagonist Therapeutics Inc | 51,185 | 22,700 | -28,485 | $3.40M | $1.98M | 1.18% | -$1.42M |
| Relmada Therapeutics, Inc.(RLMD) | 0 | 389,395 | +389,395 | $0 | $1.88M | 1.12% | +$1.88M |
| Ventyx Biosciences Inc | 71,204 | 200,000 | +128,796 | $221.4K | $1.81M | 1.08% | +$1.58M |
| Annexon, Inc.(ANNX) | 0 | 350,000 | +350,000 | $0 | $1.76M | 1.05% | +$1.76M |
| MannKind Corporation(MNKD) | 212,475 | 302,000 | +89,525 | $1.14M | $1.71M | 1.02% | +$571.3K |
| Inventiva S.A.ADS(IVA) | 0 | 334,251 | +334,251 | $0 | $1.55M | 0.93% | +$1.55M |
| BioCryst Pharmaceuticals, Inc.(BCRX) | 0 | 190,928 | +190,928 | $0 | $1.49M | 0.89% | +$1.49M |
| Ardelyx Inc | 400,000 | 252,198 | -147,802 | $2.20M | $1.47M | 0.88% | -$733.7K |
| Ascendis Pharma A/SADR(ASND) | 27,572 | 6,840 | -20,732 | $5.48M | $1.46M | 0.87% | -$4.02M |
| Xeris Biopharma Holdings Inc | 74,753 | 170,568 | +95,815 | $608.5K | $1.34M | 0.80% | +$730.5K |
| Rigel Pharmaceuticals, Inc.(RIGL) | 0 | 30,000 | +30,000 | $0 | $1.28M | 0.77% | +$1.28M |
| Soleno Therapeutics Inc | 177,330 | 26,892 | -150,438 | $11.99M | $1.25M | 0.74% | -$10.74M |
| Pacira BioSciences, Inc.(PCRX) | 58,926 | 48,025 | -10,901 | $1.52M | $1.24M | 0.74% | -$275.6K |
| Trevi Therapeutics, Inc.(TRVI) | 85,830 | 97,184 | +11,354 | $785.3K | $1.22M | 0.72% | +$431.4K |
| MapLight Therapeutics, Inc.(MPLT) | 0 | 63,791 | +63,791 | $0 | $1.12M | 0.67% | +$1.12M |
| uniQure N.V.SHS(QURE) | 0 | 45,000 | +45,000 | $0 | $1.08M | 0.64% | +$1.08M |
| Vaxcyte, Inc.(PCVX) | 218,285 | 22,972 | -195,313 | $7.86M | $1.06M | 0.63% | -$6.80M |
| Enanta Pharmaceuticals, Inc.(ENTA) | 0 | 65,138 | +65,138 | $0 | $1.03M | 0.61% | +$1.03M |
| Prothena Corp PlcSHS SHS | 0 | 106,539 | +106,539 | $0 | $1.02M | 0.61% | +$1.02M |
| Monte Rosa Therapeutics, Inc.(GLUE) | 0 | 62,281 | +62,281 | $0 | $976.6K | 0.58% | +$976.6K |
| Design Therapeutics, Inc.(DSGN) | 0 | 100,320 | +100,320 | $0 | $941.0K | 0.56% | +$941.0K |
| Inovio Pharmaceuticals, Inc.(INO) | 0 | 533,682 | +533,682 | $0 | $928.6K | 0.55% | +$928.6K |
| Mineralys Therapeutics, Inc.(MLYS) | 0 | 25,000 | +25,000 | $0 | $907.3K | 0.54% | +$907.3K |
| Aytu Biopharma Inc | 272,670 | 305,788 | +33,118 | $512.6K | $795.0K | 0.47% | +$282.4K |
| Pelthos Therapeutics Inc.(PTHS) | 10,498 | 25,000 | +14,502 | $293.9K | $775.0K | 0.46% | +$481.1K |
| Liquidia Corporation(LQDA) | 0 | 21,881 | +21,881 | $0 | $754.7K | 0.45% | +$754.7K |
| Edgewise Therapeutics, Inc.(EWTX) | 0 | 30,000 | +30,000 | $0 | $744.5K | 0.44% | +$744.5K |
| Viridian Therapeutics, Inc.(VRDN) | 0 | 21,114 | +21,114 | $0 | $657.1K | 0.39% | +$657.1K |
| Indivior Plc | 254,252 | 17,320 | -236,932 | $6.13M | $621.4K | 0.37% | -$5.51M |
| Vir Biotechnology, Inc.(VIR) | 0 | 100,000 | +100,000 | $0 | $603.0K | 0.36% | +$603.0K |
| Ligand Pharmaceuticals Incorporated(LGND) | 0 | 2,987 | +2,987 | $0 | $564.8K | 0.34% | +$564.8K |
| Upstream Bio, Inc.(UPB) | 0 | 20,500 | +20,500 | $0 | $556.6K | 0.33% | +$556.6K |
| Stoke Therapeutics, Inc.(STOK) | 0 | 17,181 | +17,181 | $0 | $545.3K | 0.32% | +$545.3K |
| Equillium, Inc.(EQ) | 300,000 | 347,393 | +47,393 | $429.0K | $538.5K | 0.32% | +$109.5K |
| UroGen Pharma Ltd.(URGN) | 90,000 | 21,810 | -68,190 | $1.80M | $510.8K | 0.30% | -$1.28M |
| Immunome, Inc.(IMNM) | 0 | 22,500 | +22,500 | $0 | $483.3K | 0.29% | +$483.3K |
| Palisade Bio, Inc.(PALI) | 0 | 166,049 | +166,049 | $0 | $390.2K | 0.23% | +$390.2K |
| Proqr Thrapeutics N VSHS EURO SHS EURO | 157,694 | 167,532 | +9,838 | $335.9K | $338.4K | 0.20% | +$2.5K |
| Harmony Biosciences Holdings, Inc.(HRMY) | 50,000 | 7,500 | -42,500 | $1.38M | $280.6K | 0.17% | -$1.10M |
| Aardvark Therapeutics Inc | 0 | 15,882 | +15,882 | $0 | $208.5K | 0.12% | +$208.5K |
| Neuphoria Therapeutics Inc | 21,452 | 50,000 | +28,548 | $252.9K | $194.0K | 0.12% | -$58.9K |
| Pliant Therapeutics, Inc.(PLRX) | 0 | 144,914 | +144,914 | $0 | $176.8K | 0.11% | +$176.8K |
| BeOne Medicines AGADS(ONC) | 0 | 7,500 | +7,500 | $0 | $172.8K | 0.10% | +$172.8K |
| Foghorn Therapeutics Inc.(FHTX) | 50,000 | 30,630 | -19,370 | $244.5K | $165.4K | 0.10% | -$79.1K |
| Talphera, Inc.(TLPH) | 0 | 136,923 | +136,923 | $0 | $156.1K | 0.09% | +$156.1K |
| PureTech Health plcADS(PRTCY) | 7,324 | 7,442 | +118 | $135.5K | $123.8K | 0.07% | -$11.7K |
| Inhibrx Biosciences, Inc.(INBX) | 0 | 1,299 | +1,299 | $0 | $102.6K | 0.06% | +$102.6K |
| Edesa Biotech, Inc.(EDSA) | 0 | 54,025 | +54,025 | $0 | $76.7K | 0.05% | +$76.7K |
| Vistagen Therapeutics, Inc.(VTGN) | 349,789 | 100,000 | -249,789 | $1.24M | $66.2K | 0.04% | -$1.18M |
| Alector Inc | 136,023 | 0 | -136,023 | $402.6K | $0 | — | -$402.6K |
| Alkermes plcSHS(ALKS) | 72,079 | 0 | -72,079 | $2.16M | $0 | — | -$2.16M |
| Amylyx Pharmaceuticals, Inc.(AMLX) | 100,000 | 0 | -100,000 | $1.36M | $0 | — | -$1.36M |
| Anaptysbio Inc | 3,295 | 0 | -3,295 | $100.9K | $0 | — | -$100.9K |
| Apogee Therapeutics Inc | 64,250 | 0 | -64,250 | $2.55M | $0 | — | -$2.55M |
| Arcturus Therapeutics Holdings Inc.(ARCT) | 48,811 | 0 | -48,811 | $899.6K | $0 | — | -$899.6K |
| Avidity Biosciences Inc | 30,000 | 0 | -30,000 | $1.31M | $0 | — | -$1.31M |
| Bristol-Myers Squibb Company(BMY) | 130,000 | 0 | -130,000 | $5.86M | $0 | — | -$5.86M |
| Catalyst Pharmaceuticals Inc | 50,000 | 0 | -50,000 | $985.0K | $0 | — | -$985.0K |
| Climb Bio, Inc.(CLYM) | 136,488 | 0 | -136,488 | $274.3K | $0 | — | -$274.3K |
| CytomX Therapeutics, Inc.(CTMX) | 185,286 | 0 | -185,286 | $591.1K | $0 | — | -$591.1K |
| Jazz Pharmaceuticals plcSHS USD(JAZZ) | 23,140 | 0 | -23,140 | $3.05M | $0 | — | -$3.05M |
| Mind Medicine Mindmed Inc | 105,891 | 0 | -105,891 | $1.25M | $0 | — | -$1.25M |
| Moderna, Inc.(MRNA) | 20,000 | 0 | -20,000 | $516.6K | $0 | — | -$516.6K |
| Nektar Therapeutics(NKTR) | 75,000 | 0 | -75,000 | $4.27M | $0 | — | -$4.27M |
| Neurocrine Biosciences, Inc.(NBIX) | 37,754 | 0 | -37,754 | $5.30M | $0 | — | -$5.30M |
| Novo Nordisk A/SADR(NVO) | 25,000 | 0 | -25,000 | $1.39M | $0 | — | -$1.39M |
| Ovid Therapeutics Inc.(OVID) | 187,739 | 0 | -187,739 | $244.1K | $0 | — | -$244.1K |
| PMV Pharmaceuticals, Inc.(PMVP) | 11,300 | 0 | -11,300 | $15.8K | $0 | — | -$15.8K |
| Pyxis Oncology, Inc.(PYXS) | 150,000 | 0 | -150,000 | $333.0K | $0 | — | -$333.0K |
| Relay Therapeutics, Inc.(RLAY) | 43,616 | 0 | -43,616 | $227.7K | $0 | — | -$227.7K |
| Reviva Pharmaceutcls Hldgs I | 2,506,921 | 0 | -2,506,921 | $924.1K | $0 | — | -$924.1K |
| Roivant Sciences Ltd.SHS(ROIV) | 120,000 | 0 | -120,000 | $1.82M | $0 | — | -$1.82M |
| Supernus Pharmaceuticals, Inc.(SUPN) | 22,348 | 0 | -22,348 | $1.07M | $0 | — | -$1.07M |
| Tenaya Therapeutics, Inc.(TNYA) | 315,519 | 0 | -315,519 | $511.1K | $0 | — | -$511.1K |
| Tvardi Therapeutics, Inc.(TVRD) | 2,185 | 0 | -2,185 | $85.1K | $0 | — | -$85.1K |
| Ultragenyx Pharmaceutical Inc.(RARE) | 9,189 | 0 | -9,189 | $276.4K | $0 | — | -$276.4K |