Securities ▲▼ | Shares | Value ($K) | |||||
|---|---|---|---|---|---|---|---|
Q3 2025 ▲▼ | Q4 2025 ▲▼ | Change ▲▼ | Q3 2025 ▲▼ | Q4 2025 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| ELECTRONIC ARTS INC | 0 | 5,035,000 | +5,035,000 | 0 | 1,028,802 | 5.35% | +1,028,802 |
| EXACT SCIENCES CORP(EXK) | 0 | 6,405,000 | +6,405,000 | 0 | 650,492 | 3.38% | +650,492 |
| REVOLUTION MEDICINES INC(RVMD) | 14,625,692 | 14,582,796 | -42,896 | 683,020 | 1,161,520 | 6.04% | +478,500 |
| CYBERARK SOFTWARE LTD | 0 | 1,053,040 | +1,053,040 | 0 | 469,719 | 2.44% | +469,719 |
| SYNOPSYS INC(SNPS) | 0 | 999,200 | +999,200 | 0 | 469,344 | 2.44% | +469,344 |
| BROADCOM INC(AVGO) | 0 | 892,400 | +892,400 | 0 | 308,860 | 1.61% | +308,860 |
| AMAZON COM INC(AMZN) | 3,505,700 | 4,499,894 | +994,194 | 769,747 | 1,038,666 | 5.40% | +268,919 |
| BRIDGEBIO PHARMA INC(BBIO) | 8,192,000 | 8,998,463 | +806,463 | 425,492 | 688,292 | 3.58% | +262,800 |
| KKR & CO INC(KKR) | 0 | 2,017,700 | +2,017,700 | 0 | 257,216 | 1.34% | +257,216 |
| BOSTON SCIENTIFIC CORP(BSX) | 4,746,557 | 7,439,564 | +2,693,007 | 463,406 | 709,362 | 3.69% | +245,956 |
| AVIDITY BIOSCIENCES INC | 0 | 3,233,000 | +3,233,000 | 0 | 233,196 | 1.21% | +233,196 |
| NATERA INC(NTRA) | 4,253,452 | 3,914,366 | -339,086 | 684,678 | 896,742 | 4.66% | +212,064 |
| DAYFORCE INC | 0 | 2,925,000 | +2,925,000 | 0 | 202,293 | 1.05% | +202,293 |
| BITWISE 10 CRYPTO INDEX ETF | 0 | 3,385,500 | +3,385,500 | 0 | 198,932 | 1.03% | +198,932 |
| LANTHEUS HLDGS INC(LNTH) | 3,477,227 | 5,427,479 | +1,950,252 | 178,347 | 361,199 | 1.88% | +182,852 |
| AON PLC(AON) | 2,278,017 | 2,665,238 | +387,221 | 812,295 | 940,509 | 4.89% | +128,214 |
| PROTAGONIST THERAPEUTICS INC | 6,196,006 | 6,144,006 | -52,000 | 411,601 | 536,617 | 2.79% | +125,017 |
| GRAIL INC(GRAL) | 1,349,000 | 2,342,684 | +993,684 | 79,766 | 200,510 | 1.04% | +120,744 |
| LIQUIDIA CORPORATION(LQDA) | 8,565,638 | 8,656,038 | +90,400 | 194,783 | 298,547 | 1.55% | +103,764 |
| WABTEC(WAB) | 2,205,098 | 2,476,003 | +270,905 | 442,056 | 528,503 | 2.75% | +86,447 |
| CRINETICS PHARMACEUTICALS IN(CRNX) | 5,770,098 | 6,933,098 | +1,163,000 | 240,325 | 322,736 | 1.68% | +82,411 |
| MICROSOFT CORP(MSFT) | 1,913,135 | 2,214,079 | +300,944 | 990,908 | 1,070,773 | 5.57% | +79,865 |
| CARDINAL HEALTH INC(CAH) | 253,000 | 576,000 | +323,000 | 39,711 | 118,368 | 0.62% | +78,657 |
| WELLTOWER INC(WELL) | 0 | 343,000 | +343,000 | 0 | 63,664 | 0.33% | +63,664 |
| BETA BIONICS INC(BBNX) | 4,313,920 | 4,313,920 | 0 | 85,718 | 131,445 | 0.68% | +45,728 |
| VISA INC(V) | 599,810 | 695,910 | +96,100 | 204,763 | 244,063 | 1.27% | +39,299 |
| TYRA BIOSCIENCES INC(TYRA) | 1,143,818 | 2,066,818 | +923,000 | 16,002 | 54,337 | 0.28% | +38,335 |
| CIDARA THERAPEUTICS INC | 508,000 | 382,800 | -125,200 | 48,646 | 84,557 | 0.44% | +35,911 |
| BEAM THERAPEUTICS INC(BEAM) | 10,063,111 | 10,063,111 | 0 | 244,232 | 278,949 | 1.45% | +34,718 |
| STRUCTURE THERAPEUTICS INC | 0 | 454,000 | +454,000 | 0 | 31,576 | 0.16% | +31,576 |
| SUNOCOCORP LLC(SUNC) | 0 | 606,277 | +606,277 | 0 | 29,877 | 0.16% | +29,877 |
| CENTESSA PHARMACEUTICALS PLC | 4,331,318 | 5,377,068 | +1,045,750 | 105,034 | 134,480 | 0.70% | +29,446 |
| PERCEPTIVE CAP SOLUTIONS COR CL A ORD SHS | 0 | 2,250,000 | +2,250,000 | 0 | 29,318 | 0.15% | +29,318 |
| TERNS PHARMACEUTICALS INC | 0 | 642,000 | +642,000 | 0 | 25,937 | 0.13% | +25,937 |
| TANGO THERAPEUTICS INC(TNGX) | 10,757,000 | 13,061,411 | +2,304,411 | 90,359 | 115,724 | 0.60% | +25,365 |
| SCHWAB CHARLES CORP(SCHW) | 3,251,657 | 3,339,657 | +88,000 | 310,436 | 333,665 | 1.73% | +23,229 |
| AMKOR TECHNOLOGY INC | 0 | 464,000 | +464,000 | 0 | 18,319 | 0.10% | +18,319 |
| ENANTA PHARMACEUTICALS INC(ENTA) | 2,122,262 | 2,772,262 | +650,000 | 25,403 | 43,719 | 0.23% | +18,315 |
| VERASTEM INC(VSTM) | 0 | 2,000,000 | +2,000,000 | 0 | 15,440 | 0.08% | +15,440 |
| BAIDU INC | 207,996 | 315,300 | +107,304 | 27,408 | 41,197 | 0.21% | +13,789 |
| MEDLINE INC(MDLN) | 0 | 260,000 | +260,000 | 0 | 10,920 | 0.06% | +10,920 |
| GUARDANT HEALTH INC(GH) | 8,000 | 109,000 | +101,000 | 500 | 11,133 | 0.06% | +10,633 |
| ASSEMBLY BIOSCIENCES INC | 1,227,590 | 1,227,590 | 0 | 31,426 | 41,750 | 0.22% | +10,324 |
| MINERVA NEUROSCIENCES INC(NERV) | 0 | 2,365,000 | +2,365,000 | 0 | 9,507 | 0.05% | +9,507 |
| GENEDX HOLDINGS CORP(WGS) | 5,000 | 70,000 | +65,000 | 539 | 9,104 | 0.05% | +8,566 |
| GRAYSCALE ETHEREUM MINI TR E(ETH) | 0 | 228,340 | +228,340 | 0 | 6,407 | 0.03% | +6,407 |
| CAPRICOR THERAPEUTICS INC(CAPR) | 41,000 | 41,000 | 0 | 296 | 1,183 | 0.01% | +888 |
| JOYY INC(JOYY) | 625,000 | 578,200 | -46,800 | 36,631 | 37,444 | 0.19% | +813 |
| ARROWHEAD PHARMACEUTICALS IN(ARWR) | 15,800 | 15,800 | 0 | 545 | 1,049 | 0.01% | +504 |
| MADRIGAL PHARMACEUTICALS INC(MDGL) | 3,319 | 3,319 | 0 | 1,522 | 1,933 | 0.01% | +410 |
| CELCUITY INC(CELC) | 0 | 4,000 | +4,000 | 0 | 399 | 0.00% | +399 |
| OMEROS CORP(OMER) | 0 | 23,000 | +23,000 | 0 | 395 | 0.00% | +395 |
| COGENT BIOSCIENCES INC(COGT) | 17,000 | 17,000 | 0 | 244 | 604 | 0.00% | +360 |
| SUMMIT MIDSTREAM CORPORATION(SMC) | 58,214 | 58,214 | 0 | 1,196 | 1,553 | 0.01% | +357 |
| STOKE THERAPEUTICS INC(STOK) | 0 | 9,000 | +9,000 | 0 | 286 | 0.00% | +286 |
| ARCUTIS BIOTHERAPEUTICS INC(ARQT) | 26,000 | 26,000 | 0 | 490 | 755 | 0.00% | +265 |
| NUVATION BIO INC(NUVB) | 0 | 29,000 | +29,000 | 0 | 260 | 0.00% | +260 |
| AXSOME THERAPEUTICS INC(AXSM) | 4,000 | 4,000 | 0 | 486 | 731 | 0.00% | +245 |
| ROIVANT SCIENCES LTD(ROIV) | 37,000 | 37,000 | 0 | 560 | 803 | 0.00% | +243 |
| VAXCYTE INC(PCVX) | 0 | 5,000 | +5,000 | 0 | 231 | 0.00% | +231 |
| NEOGENOMICS INC(NEO) | 0 | 19,000 | +19,000 | 0 | 223 | 0.00% | +223 |
| ESTABLISHMENT LABS HLDGS INC(ESTA) | 0 | 3,000 | +3,000 | 0 | 219 | 0.00% | +219 |
| OCULAR THERAPEUTIX INC(OCUL) | 0 | 18,000 | +18,000 | 0 | 219 | 0.00% | +219 |
| PRECIGEN INC(PGEN) | 0 | 50,000 | +50,000 | 0 | 209 | 0.00% | +209 |
| ADAPTIVE BIOTECHNOLOGIES COR(ADPT) | 0 | 11,000 | +11,000 | 0 | 179 | 0.00% | +179 |
| BRIGHTSPRING HEALTH SVCS INC(BTSG) | 22,000 | 22,000 | 0 | 650 | 824 | 0.00% | +174 |
| TRAVERE THERAPEUTICS INC(TVTX) | 12,000 | 12,000 | 0 | 287 | 459 | 0.00% | +172 |
| ALEANNA INC(ANNA) | 78,400 | 78,400 | 0 | 62 | 223 | 0.00% | +162 |
| KRYSTAL BIOTECH INC(KRYS) | 2,000 | 2,000 | 0 | 353 | 493 | 0.00% | +140 |
| GLOBUS MED INC(GMED) | 4,000 | 4,000 | 0 | 229 | 349 | 0.00% | +120 |
| SOLID POWER INC(SLDP) | 405,316 | 405,316 | 0 | 168 | 287 | 0.00% | +118 |
| IMMUNOVANT INC(IMVT) | 12,000 | 12,000 | 0 | 193 | 305 | 0.00% | +112 |
| RANI THERAPEUTICS HLDGS INC(RANI) | 0 | 78,000 | +78,000 | 0 | 105 | 0.00% | +105 |
| AMICUS THERAPEUTICS INC COM | 16,000 | 16,000 | 0 | 126 | 228 | 0.00% | +102 |
| INSMED INC(INSM) | 3,000 | 3,000 | 0 | 432 | 522 | 0.00% | +90 |
| GLAUKOS CORP(GKOS) | 2,600 | 2,600 | 0 | 212 | 294 | 0.00% | +82 |
| PACIFIC BIOSCIENCES CALIF IN(PACB) | 135,000 | 135,000 | 0 | 173 | 252 | 0.00% | +80 |
| REVOLUTION MEDICINES INC(RVMD) | 120,085 | 120,085 | 0 | 36 | 113 | 0.00% | +77 |
| PROGYNY INC | 18,000 | 18,000 | 0 | 387 | 462 | 0.00% | +75 |
| DYNE THERAPEUTICS INC(DYN) | 10,000 | 10,000 | 0 | 127 | 196 | 0.00% | +69 |
| IONIS PHARMACEUTICALS INC(IONS) | 4,800 | 4,800 | 0 | 314 | 380 | 0.00% | +66 |
| SYNDAX PHARMACEUTICALS INC(SNDX) | 10,000 | 10,000 | 0 | 154 | 210 | 0.00% | +56 |
| LIVANOVA PLC(LIVN) | 6,000 | 6,000 | 0 | 314 | 369 | 0.00% | +55 |
| VERACYTE INC(VCYT) | 7,000 | 7,000 | 0 | 240 | 295 | 0.00% | +54 |
| SCHOLAR ROCK HLDG CORP(SRRK) | 7,000 | 7,000 | 0 | 261 | 308 | 0.00% | +48 |
| NUVALENT INC | 3,000 | 3,000 | 0 | 259 | 302 | 0.00% | +42 |
| UROGEN PHARMA LTD(URGN) | 11,000 | 11,000 | 0 | 219 | 258 | 0.00% | +38 |
| TWIST BIOSCIENCE CORP(TWST) | 7,650 | 7,650 | 0 | 215 | 243 | 0.00% | +27 |
| IRONWOOD PHARMACEUTICALS INC(IRWD) | 13,000 | 13,000 | 0 | 17 | 44 | 0.00% | +27 |
| CENCORA INC | 1,000 | 1,000 | 0 | 313 | 338 | 0.00% | +25 |
| GE HEALTHCARE TECHNOLOGIES I(GEHC) | 3,000 | 3,000 | 0 | 225 | 246 | 0.00% | +21 |
| ASCENDIS PHARMA A/S(ASND) | 1,400 | 1,400 | 0 | 278 | 299 | 0.00% | +20 |
| MIRUM PHARMACEUTICALS INC(MIRM) | 3,000 | 3,000 | 0 | 220 | 237 | 0.00% | +17 |
| MERIT MED SYS INC(MMSI) | 3,000 | 3,000 | 0 | 250 | 264 | 0.00% | +15 |
| IOVANCE BIOTHERAPEUTICS INC(IOVA) | 26,000 | 26,000 | 0 | 56 | 71 | 0.00% | +15 |
| CG ONCOLOGY INC(CGON) | 8,000 | 8,000 | 0 | 322 | 332 | 0.00% | +10 |
| ICON PLC(ICLR) | 1,200 | 1,200 | 0 | 210 | 219 | 0.00% | +9 |
| ARDELYX INC | 23,000 | 23,000 | 0 | 127 | 134 | 0.00% | +7 |
| BIOCRYST PHARMACEUTICALS INC(BCRX) | 24,000 | 24,000 | 0 | 182 | 187 | 0.00% | +5 |
| SABRA HEALTH CARE REIT INC(SBRA) | 14,000 | 14,000 | 0 | 261 | 265 | 0.00% | +4 |