| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| BlackRock, Inc. | 21,494,972 | 21,813,306 | +318,334 | 0.02 | 0.02 | -0.00 | buy |
| VANGUARD GROUP INC | 15,604,512 | 15,809,317 | +204,805 | 0.01 | 0.01 | -0.00 | buy |
| STATE STREET CORP | 7,433,899 | 7,618,238 | +184,339 | 0.01 | 0.01 | -0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 3,282,567 | 3,490,457 | +207,890 | 0.01 | 0.01 | -0.00 | buy |
| Clearbridge Investments, LLC | 2,644,457 | 3,052,556 | +408,099 | 0.09 | 0.09 | -0.00 | buy |
| Soleus Capital Management, L.P. | 2,846,703 | 2,243,935 | -602,768 | 8.80 | 5.58 | -3.22 | sell |
| Pictet Asset Management Holding SA | 2,397,184 | 1,907,491 | -489,693 | 0.11 | 0.07 | -0.04 | sell |
| GOLDMAN SACHS GROUP INC | 1,919,416 | 1,569,909 | -349,507 | 0.01 | 0.01 | -0.01 | sell |
| Hood River Capital Management LLC | 1,556,488 | 1,567,506 | +11,018 | 1.05 | 0.79 | -0.26 | buy |
| FMR LLC | 1,743,354 | 1,551,973 | -191,381 | 0.00 | 0.00 | -0.00 | sell |
| PRICE T ROWE ASSOCIATES INC /MD/ | 390,528 | 1,547,544 | +1,157,016 | 0.00 | 0.01 | +0.00 | buy |
| NORTHERN TRUST CORP | 1,529,407 | 1,535,723 | +6,316 | 0.01 | 0.01 | -0.00 | buy |
| MORGAN STANLEY | 2,050,548 | 1,402,613 | -647,935 | 0.01 | 0.00 | -0.00 | sell |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 1,262,937 | 1,316,496 | +53,559 | 0.01 | 0.01 | -0.00 | buy |
| WELLINGTON MANAGEMENT GROUP LLP | 1,213,039 | 1,229,599 | +16,560 | 0.01 | 0.01 | -0.00 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 659,660 | 1,208,154 | +548,494 | 0.04 | 0.07 | +0.02 | buy |
| CITADEL ADVISORS LLC | 645,877 | 1,044,468 | +398,591 | 0.02 | 0.03 | +0.01 | buy |
| Invesco Ltd. | 1,210,842 | 969,905 | -240,937 | 0.01 | 0.01 | -0.00 | sell |
| EVENTIDE ASSET MANAGEMENT, LLC | 718,814 | 954,531 | +235,717 | 0.56 | 0.60 | +0.04 | buy |
| Bank of New York Mellon Corp | 892,800 | 906,475 | +13,675 | 0.01 | 0.01 | -0.00 | buy |
| DRIEHAUS CAPITAL MANAGEMENT LLC | 774,656 | 807,833 | +33,177 | 0.29 | 0.23 | -0.06 | buy |
| PRINCIPAL FINANCIAL GROUP INC | 841,011 | 796,674 | -44,337 | 0.02 | 0.02 | -0.00 | sell |
| Point72 Asset Management, L.P. | 0 | 717,510 | +717,510 | 0.00 | 0.06 | +0.06 | buy |
| JANE STREET GROUP, LLC | 359,194 | 705,012 | +345,818 | 0.03 | 0.04 | +0.02 | buy |
| BALYASNY ASSET MANAGEMENT L.P. | 0 | 696,125 | +696,125 | 0.00 | 0.06 | +0.06 | buy |
| CITIGROUP INC | 349,104 | 686,022 | +336,918 | 0.01 | 0.02 | +0.01 | buy |
| RAYMOND JAMES FINANCIAL INC | 687,100 | 678,758 | -8,342 | 0.01 | 0.01 | -0.00 | sell |
| ROYAL BANK OF CANADA | 75,692 | 673,370 | +597,678 | 0.00 | 0.00 | +0.00 | buy |
| Nuveen, LLC | 746,696 | 657,153 | -89,543 | 0.01 | 0.01 | -0.00 | sell |
| BARCLAYS PLC | 253,094 | 620,546 | +367,452 | 0.00 | 0.01 | +0.00 | buy |
| MILLENNIUM MANAGEMENT LLC | 89,736 | 615,733 | +525,997 | 0.00 | 0.02 | +0.02 | buy |
| TWO SIGMA INVESTMENTS, LP | 793,639 | 613,707 | -179,932 | 0.07 | 0.04 | -0.03 | sell |
| Woodline Partners LP | 533,134 | 594,620 | +61,486 | 0.14 | 0.11 | -0.02 | buy |
| BANK OF AMERICA CORP /DE/ | 684,476 | 567,378 | -117,098 | 0.00 | 0.00 | -0.00 | sell |
| LORD, ABBETT & CO. LLC | 0 | 557,966 | +557,966 | 0.00 | 0.06 | +0.06 | buy |
| Opaleye Management Inc. | 535,000 | 535,000 | 0 | 4.70 | 3.90 | -0.80 | hold |
| UBS Group AG | 631,691 | 531,441 | -100,250 | 0.01 | 0.00 | -0.00 | sell |
| BANK OF MONTREAL /CAN/ | 524,475 | 525,244 | +769 | 0.01 | 0.01 | -0.00 | buy |
| BRAUN STACEY ASSOCIATES INC | 502,650 | 518,015 | +15,365 | 0.81 | 0.67 | -0.14 | buy |
| GROUP ONE TRADING LLC | 301,634 | 464,525 | +162,891 | 0.50 | 0.55 | +0.05 | buy |
| PUBLIC SECTOR PENSION INVESTMENT BOARD | 423,318 | 462,360 | +39,042 | 0.07 | 0.07 | -0.00 | buy |
| First Turn Management, LLC | 400,644 | 447,884 | +47,240 | 3.18 | 3.01 | -0.18 | buy |
| Penn Capital Management Company, LLC | 392,182 | 443,365 | +51,183 | 1.51 | 1.38 | -0.13 | buy |
| VOYA INVESTMENT MANAGEMENT LLC | 300,453 | 422,781 | +122,328 | 0.01 | 0.02 | +0.00 | buy |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 287,059 | 409,393 | +122,334 | 0.00 | 0.00 | +0.00 | buy |
| RHUMBLINE ADVISERS | 381,854 | 404,660 | +22,806 | 0.01 | 0.01 | -0.00 | buy |
| AMERIPRISE FINANCIAL INC | 425,982 | 396,064 | -29,918 | 0.00 | 0.00 | -0.00 | sell |
| COMMONWEALTH OF PENNSYLVANIA PUBLIC SCHOOL EMPLS RETRMT SYS | 31,941 | 387,262 | +355,321 | 0.01 | 0.02 | +0.01 | buy |
| DIADEMA PARTNERS LP | 207,883 | 371,448 | +163,565 | 6.55 | 8.31 | +1.76 | buy |
| Legal & General Group Plc | 381,132 | 366,141 | -14,991 | 0.00 | 0.00 | -0.00 | sell |
| Russell Investments Group, Ltd. | 152,214 | 348,483 | +196,269 | 0.01 | 0.02 | +0.01 | buy |
| NEW YORK STATE COMMON RETIREMENT FUND | 293,279 | 332,846 | +39,567 | 0.02 | 0.02 | -0.00 | buy |
| Jump Financial, LLC | 49,100 | 320,022 | +270,922 | 0.03 | 0.15 | +0.12 | buy |
| WELLS FARGO & COMPANY/MN | 293,540 | 316,589 | +23,049 | 0.00 | 0.00 | -0.00 | buy |
| Ensign Peak Advisors, Inc | 328,992 | 308,092 | -20,900 | 0.02 | 0.02 | -0.01 | sell |
| Swiss National Bank | 286,500 | 285,200 | -1,300 | 0.01 | 0.01 | -0.00 | sell |
| Marex Group plc | 275,000 | 278,316 | +3,316 | 0.21 | 0.19 | -0.02 | buy |
| CASTLEARK MANAGEMENT LLC | 237,090 | 250,430 | +13,340 | 0.32 | 0.27 | -0.05 | buy |
| Cubist Systematic Strategies, LLC | 0 | 243,986 | +243,986 | 0.00 | 0.10 | +0.10 | buy |
| Ikarian Capital, LLC | 210,065 | 209,938 | -127 | 2.70 | 2.50 | -0.20 | sell |
| FIRST TRUST ADVISORS LP | 222,792 | 197,381 | -25,411 | 0.01 | 0.01 | -0.00 | sell |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 199,050 | 192,323 | -6,727 | 0.02 | 0.01 | -0.00 | sell |
| IFP Advisors, Inc | 188,062 | 190,697 | +2,635 | 0.23 | 0.20 | -0.03 | buy |
| PRUDENTIAL FINANCIAL INC | 179,390 | 189,315 | +9,925 | 0.01 | 0.01 | -0.00 | buy |
| Rafferty Asset Management, LLC | 181,861 | 188,220 | +6,359 | 0.03 | 0.02 | -0.01 | buy |
| ALLIANCEBERNSTEIN L.P. | 169,410 | 177,060 | +7,650 | 0.00 | 0.00 | -0.00 | buy |
| COMMONWEALTH EQUITY SERVICES, LLC | 175,768 | 172,303 | -3,465 | 0.01 | 0.01 | -0.00 | sell |
| LPL Financial LLC | 185,063 | 165,103 | -19,960 | 0.00 | 0.00 | -0.00 | sell |
| M28 Capital Management LP | 161,600 | 161,600 | 0 | 8.73 | 9.92 | +1.19 | hold |
| STATE OF WISCONSIN INVESTMENT BOARD | 179,306 | 156,319 | -22,987 | 0.02 | 0.01 | -0.00 | sell |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 135,530 | 149,512 | +13,982 | 0.01 | 0.01 | -0.00 | buy |
| Nicholas Investment Partners, LP | 109,739 | 146,941 | +37,202 | 0.45 | 0.47 | +0.03 | buy |
| JPMORGAN CHASE & CO | 588,004 | 146,027 | -441,977 | 0.00 | 0.00 | -0.00 | sell |
| 1832 Asset Management L.P. | 1,483,800 | 144,000 | -1,339,800 | 0.11 | 0.01 | -0.10 | sell |
| Man Group plc | 0 | 139,765 | +139,765 | 0.00 | 0.01 | +0.01 | buy |
| DEUTSCHE BANK AG\ | 148,705 | 136,924 | -11,781 | 0.00 | 0.00 | -0.00 | sell |
| HUSSMAN STRATEGIC ADVISORS, INC. | 52,500 | 126,000 | +73,500 | 0.50 | 1.04 | +0.53 | buy |
| FEDERATED HERMES, INC. | 66,303 | 125,048 | +58,745 | 0.01 | 0.01 | +0.00 | buy |
| TWO SIGMA ADVISERS, LP | 132,400 | 123,500 | -8,900 | 0.01 | 0.01 | -0.00 | sell |
| NEW YORK STATE TEACHERS RETIREMENT SYSTEM | 120,364 | 120,864 | +500 | 0.01 | 0.01 | -0.00 | buy |
| D. E. Shaw & Co., Inc. | 61,930 | 118,137 | +56,207 | 0.00 | 0.00 | +0.00 | buy |
| CANADA LIFE ASSURANCE Co | 117,311 | 116,888 | -423 | 0.01 | 0.01 | -0.00 | sell |
| Rhenman & Partners Asset Management AB | 177,500 | 115,000 | -62,500 | 0.80 | 0.52 | -0.28 | sell |
| OSAIC HOLDINGS, INC. | 152,790 | 113,345 | -39,445 | 0.01 | 0.01 | -0.01 | sell |
| VICTORY CAPITAL MANAGEMENT INC | 92,081 | 105,983 | +13,902 | 0.00 | 0.00 | -0.00 | buy |
| MIRAE ASSET SECURITIES (USA) INC. | 180,752 | 100,260 | -80,492 | 0.31 | 0.16 | -0.15 | sell |
| Quantum Private Wealth, LLC | 100,008 | 100,008 | 0 | 1.49 | 1.17 | -0.33 | hold |
| TANG CAPITAL MANAGEMENT LLC | 100,000 | 100,000 | 0 | 0.22 | 0.18 | -0.04 | hold |
| THRIVENT FINANCIAL FOR LUTHERANS | 98,038 | 99,715 | +1,677 | 0.01 | 0.01 | -0.00 | buy |
| Hennion & Walsh Asset Management, Inc. | 95,171 | 93,771 | -1,400 | 0.17 | 0.14 | -0.03 | sell |
| NJ State Employees Deferred Compensation Plan | 91,600 | 91,600 | 0 | 0.46 | 0.39 | -0.07 | hold |
| FRANKLIN RESOURCES INC | 72,935 | 91,387 | +18,452 | 0.00 | 0.00 | +0.00 | buy |
| NORGES BANK | 218,346 | 89,820 | -128,526 | 0.00 | 0.00 | -0.00 | sell |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 91,593 | 88,806 | -2,787 | 0.01 | 0.01 | -0.00 | sell |
| FRED ALGER MANAGEMENT, LLC | 0 | 88,198 | +88,198 | 0.00 | 0.01 | +0.01 | buy |
| MetLife Investment Management, LLC | 81,232 | 86,535 | +5,303 | 0.02 | 0.02 | +0.00 | buy |
| Point72 Europe (London) LLP | 0 | 85,864 | +85,864 | 0.00 | 0.16 | +0.16 | buy |
| Persistent Asset Partners Ltd | 36,072 | 85,580 | +49,508 | 1.26 | 2.70 | +1.44 | buy |
| SECTOR GAMMA AS | 55,000 | 82,000 | +27,000 | 0.69 | 0.96 | +0.27 | buy |
| State of Alaska, Department of Revenue | 73,956 | 80,783 | +6,827 | 0.03 | 0.03 | -0.00 | buy |