| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| BANK OF AMERICA CORP /DE/ | 219,121 | 2,702,874 | +2,483,753 | 0.00 | 0.01 | +0.01 | buy |
| Point72 Asset Management, L.P. | 169,913 | 1,722,984 | +1,553,071 | 0.02 | 0.19 | +0.17 | buy |
| UBS Group AG | 1,201,999 | 2,134,219 | +932,220 | 0.01 | 0.02 | +0.01 | buy |
| Paradigm Biocapital Advisors LP | 0 | 858,664 | +858,664 | 0.00 | 1.59 | +1.59 | buy |
| JENNISON ASSOCIATES LLC | 0 | 673,932 | +673,932 | 0.00 | 0.02 | +0.02 | buy |
| JANE STREET GROUP, LLC | 108,122 | 755,706 | +647,584 | 0.01 | 0.05 | +0.05 | buy |
| Deep Track Capital, LP | 2,500,000 | 3,073,853 | +573,853 | 4.41 | 4.00 | -0.41 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 139,117 | 539,110 | +399,993 | 0.01 | 0.04 | +0.03 | buy |
| PRINCIPAL FINANCIAL GROUP INC | 271,133 | 629,911 | +358,778 | 0.01 | 0.01 | +0.01 | buy |
| E. Ohman J:or Asset Management AB | 0 | 329,231 | +329,231 | 0.00 | 0.35 | +0.35 | buy |
| Hood River Capital Management LLC | 989,248 | 1,256,580 | +267,332 | 0.69 | 0.86 | +0.17 | buy |
| Polar Capital Holdings Plc | 2,196,721 | 2,455,737 | +259,016 | 0.58 | 0.60 | +0.02 | buy |
| Vestal Point Capital, LP | 2,350,000 | 2,590,531 | +240,531 | 6.55 | 7.43 | +0.88 | buy |
| MILLENNIUM MANAGEMENT LLC | 50,525 | 287,901 | +237,376 | 0.00 | 0.01 | +0.01 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 24,647 | 237,598 | +212,951 | 0.00 | 0.01 | +0.01 | buy |
| GROUP ONE TRADING LLC | 0 | 204,512 | +204,512 | 0.00 | 0.34 | +0.34 | buy |
| SCHRODER INVESTMENT MANAGEMENT GROUP | 149,433 | 345,598 | +196,165 | 0.01 | 0.02 | +0.01 | buy |
| NORGES BANK | 989,721 | 1,176,919 | +187,198 | 0.01 | 0.01 | +0.00 | buy |
| Fisher Asset Management, LLC | 616,492 | 793,458 | +176,966 | 0.01 | 0.01 | +0.00 | buy |
| Schonfeld Strategic Advisors LLC | 0 | 175,478 | +175,478 | 0.00 | 0.05 | +0.05 | buy |
| Cutter Capital Management, LP | 0 | 175,000 | +175,000 | 0.00 | 3.06 | +3.06 | buy |
| GOLDMAN SACHS GROUP INC | 1,205,431 | 1,362,958 | +157,527 | 0.01 | 0.01 | -0.00 | buy |
| Aberdeen Group plc | 450,513 | 602,421 | +151,908 | 0.04 | 0.05 | +0.01 | buy |
| EVENTIDE ASSET MANAGEMENT, LLC | 254,148 | 382,696 | +128,548 | 0.22 | 0.31 | +0.09 | buy |
| Catalio Capital Management, LP | 457,587 | 585,812 | +128,225 | 4.71 | 5.84 | +1.13 | buy |
| WELLINGTON MANAGEMENT GROUP LLP | 7,888,697 | 7,988,740 | +100,043 | 0.07 | 0.06 | -0.01 | buy |
| Integral Health Asset Management, LLC | 1,000,000 | 1,100,000 | +100,000 | 4.16 | 4.90 | +0.74 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 2,841,338 | 2,937,484 | +96,146 | 0.01 | 0.01 | -0.00 | buy |
| BlackRock, Inc. | 15,469,378 | 15,563,778 | +94,400 | 0.01 | 0.01 | -0.00 | buy |
| READYSTATE ASSET MANAGEMENT LP | 60,975 | 148,169 | +87,194 | 0.12 | 0.30 | +0.18 | buy |
| Woodline Partners LP | 126,201 | 212,303 | +86,102 | 0.04 | 0.06 | +0.02 | buy |
| Squarepoint Ops LLC | 19,839 | 103,878 | +84,039 | 0.00 | 0.01 | +0.01 | buy |
| ExodusPoint Capital Management, LP | 9,324 | 85,863 | +76,539 | 0.00 | 0.05 | +0.04 | buy |
| Capital International Investors | 1,096,164 | 1,168,110 | +71,946 | 0.01 | 0.01 | -0.00 | buy |
| STEMPOINT CAPITAL LP | 83,576 | 149,648 | +66,072 | 0.99 | 1.92 | +0.93 | buy |
| ALGERT GLOBAL LLC | 58,680 | 116,320 | +57,640 | 0.06 | 0.12 | +0.05 | buy |
| Qube Research & Technologies Ltd | 63,530 | 117,220 | +53,690 | 0.00 | 0.01 | +0.00 | buy |
| Cinctive Capital Management LP | 0 | 52,321 | +52,321 | 0.00 | 0.17 | +0.17 | buy |
| Pictet Asset Management Holding SA | 1,911,999 | 1,956,327 | +44,328 | 0.10 | 0.09 | -0.01 | buy |
| Zimmer Partners, LP | 38,000 | 82,132 | +44,132 | 0.03 | 0.07 | +0.04 | buy |
| CM Management, LLC | 0 | 40,000 | +40,000 | 0.00 | 1.62 | +1.62 | buy |
| Exome Asset Management LLC | 65,883 | 103,483 | +37,600 | 2.33 | 3.73 | +1.39 | buy |
| LAZARD ASSET MANAGEMENT LLC | 0 | 36,168 | +36,168 | 0.00 | 0.00 | +0.00 | buy |
| AMERIPRISE FINANCIAL INC | 752,401 | 786,583 | +34,182 | 0.01 | 0.01 | -0.00 | buy |
| Mirador Capital Partners LP | 65,636 | 99,125 | +33,489 | 0.56 | 0.70 | +0.14 | buy |
| BNP Paribas Asset Management Holding S.A. | 489,362 | 522,468 | +33,106 | 0.06 | 0.06 | -0.00 | buy |
| JANUS HENDERSON GROUP PLC | 1,024,417 | 1,057,146 | +32,729 | 0.02 | 0.03 | +0.00 | buy |
| RFG Advisory, LLC | 0 | 32,005 | +32,005 | 0.00 | 0.03 | +0.03 | buy |
| HighVista Strategies LLC | 14,261 | 44,749 | +30,488 | 0.25 | 0.69 | +0.44 | buy |
| WESTFIELD CAPITAL MANAGEMENT CO LP | 1,279,990 | 1,310,336 | +30,346 | 0.26 | 0.26 | -0.01 | buy |
| CW Advisors, LLC | 0 | 28,000 | +28,000 | 0.00 | 0.01 | +0.01 | buy |
| DAVIDSON KEMPNER CAPITAL MANAGEMENT LP | 179,061 | 206,844 | +27,783 | 0.15 | 0.12 | -0.03 | buy |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0 | 24,935 | +24,935 | 0.00 | 0.00 | +0.00 | buy |
| FOX RUN MANAGEMENT, L.L.C. | 0 | 23,181 | +23,181 | 0.00 | 0.14 | +0.14 | buy |
| DIADEMA PARTNERS LP | 0 | 20,000 | +20,000 | 0.00 | 0.64 | +0.64 | buy |
| Edgestream Partners, L.P. | 0 | 18,216 | +18,216 | 0.00 | 0.02 | +0.02 | buy |
| SIMPLEX TRADING, LLC | 0 | 17,934 | +17,934 | 0.00 | 0.03 | +0.03 | buy |
| INTECH INVESTMENT MANAGEMENT LLC | 50,273 | 67,261 | +16,988 | 0.02 | 0.03 | +0.00 | buy |
| Graham Capital Management, L.P. | 0 | 15,991 | +15,991 | 0.00 | 0.02 | +0.02 | buy |
| CAPITAL FUND MANAGEMENT S.A. | 40,446 | 55,264 | +14,818 | 0.02 | 0.03 | +0.01 | buy |
| J. Safra Sarasin Holding AG | 13,027 | 27,791 | +14,764 | 0.01 | 0.02 | +0.01 | buy |
| CIBC WORLD MARKETS CORP | 10,696 | 25,361 | +14,665 | 0.00 | 0.01 | +0.01 | buy |
| Walleye Capital LLC | 0 | 14,130 | +14,130 | 0.00 | 0.01 | +0.01 | buy |
| Quinn Opportunity Partners LLC | 115,939 | 129,939 | +14,000 | 0.39 | 0.37 | -0.03 | buy |
| Verition Fund Management LLC | 20,282 | 34,037 | +13,755 | 0.00 | 0.01 | +0.00 | buy |
| D. E. Shaw & Co., Inc. | 0 | 13,302 | +13,302 | 0.00 | 0.00 | +0.00 | buy |
| WOLVERINE TRADING, LLC | 0 | 13,066 | +13,066 | 0.00 | 0.02 | +0.02 | buy |
| Creative Planning | 21,304 | 33,577 | +12,273 | 0.00 | 0.00 | +0.00 | buy |
| Nebula Research & Development LLC | 0 | 12,165 | +12,165 | 0.00 | 0.05 | +0.05 | buy |
| NATIXIS ADVISORS, LLC | 33,659 | 45,465 | +11,806 | 0.00 | 0.00 | +0.00 | buy |
| CITIGROUP INC | 295,130 | 305,595 | +10,465 | 0.01 | 0.01 | -0.00 | buy |
| GREAT POINT PARTNERS LLC | 360,000 | 370,000 | +10,000 | 7.98 | 8.08 | +0.10 | buy |
| PRUDENTIAL FINANCIAL INC | 25,336 | 35,226 | +9,890 | 0.00 | 0.00 | +0.00 | buy |
| BROWN ADVISORY INC | 1,076,431 | 1,086,300 | +9,869 | 0.06 | 0.06 | -0.00 | buy |
| INCEPTIONR LLC | 0 | 9,433 | +9,433 | 0.00 | 0.11 | +0.11 | buy |
| ROYAL BANK OF CANADA | 44,125 | 53,547 | +9,422 | 0.00 | 0.00 | +0.00 | buy |
| PRELUDE CAPITAL MANAGEMENT, LLC | 20,206 | 28,554 | +8,348 | 0.08 | 0.12 | +0.04 | buy |
| BANQUE PICTET & CIE SA | 0 | 8,203 | +8,203 | 0.00 | 0.00 | +0.00 | buy |
| HARBOR CAPITAL ADVISORS, INC. | 45,130 | 53,113 | +7,983 | 0.09 | 0.10 | +0.00 | buy |
| UNITED SERVICES AUTOMOBILE ASSOCIATION | 0 | 7,663 | +7,663 | 0.00 | 0.01 | +0.01 | buy |
| COMERICA BANK | 235,464 | 243,109 | +7,645 | 0.04 | 0.04 | -0.00 | buy |
| Carlson Capital, L.P. | 0 | 7,500 | +7,500 | 0.00 | 0.17 | +0.17 | buy |
| QUADRANT CAPITAL GROUP LLC | 3,683 | 11,013 | +7,330 | 0.01 | 0.02 | +0.00 | buy |
| SIH Partners, LLLP | 0 | 7,307 | +7,307 | 0.00 | 0.03 | +0.03 | buy |
| SG Americas Securities, LLC | 0 | 6,731 | +6,731 | 0.00 | 0.00 | +0.00 | buy |
| Neuberger Berman Group LLC | 0 | 6,690 | +6,690 | 0.00 | 0.00 | +0.00 | buy |
| Corient Private Wealth LLC | 0 | 6,416 | +6,416 | 0.00 | 0.00 | +0.00 | buy |
| Cannon Global Investment Management, LLC | 0 | 6,000 | +6,000 | 0.00 | 0.66 | +0.66 | buy |
| Hudson Bay Capital Management LP | 141,269 | 147,263 | +5,994 | 0.04 | 0.04 | -0.00 | buy |
| Bayforest Capital Ltd | 1,689 | 7,372 | +5,683 | 0.10 | 0.13 | +0.03 | buy |
| One68 Global Capital, LLC | 0 | 5,549 | +5,549 | 0.00 | 0.11 | +0.11 | buy |
| AlphaQuest LLC | 1,136 | 6,650 | +5,514 | 0.01 | 0.03 | +0.02 | buy |
| PEREGRINE CAPITAL MANAGEMENT LLC | 150,343 | 155,737 | +5,394 | 0.21 | 0.21 | -0.00 | buy |
| TEACHERS RETIREMENT SYSTEM OF THE STATE OF KENTUCKY | 55,075 | 60,357 | +5,282 | 0.02 | 0.02 | -0.00 | buy |
| WINTON GROUP Ltd | 19,005 | 24,255 | +5,250 | 0.06 | 0.06 | -0.00 | buy |
| Vanguard Personalized Indexing Management, LLC | 6,986 | 12,082 | +5,096 | 0.00 | 0.01 | +0.00 | buy |
| Symmetry Investments LP | 0 | 5,000 | +5,000 | 0.00 | 0.02 | +0.02 | buy |
| Allostery Investments LP | 65,000 | 70,000 | +5,000 | 6.00 | 4.06 | -1.94 | buy |
| AMERICAN CENTURY COMPANIES INC | 356,576 | 361,388 | +4,812 | 0.01 | 0.01 | -0.00 | buy |
| Persistent Asset Partners Ltd | 0 | 4,576 | +4,576 | 0.00 | 0.16 | +0.16 | buy |