| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| BlackRock, Inc. | 19,298,929 | 19,461,349 | +162,420 | 0.00 | 0.00 | +0.00 | buy |
| VANGUARD GROUP INC | 13,903,735 | 13,828,355 | -75,380 | 0.00 | 0.00 | +0.00 | sell |
| First Light Asset Management, LLC | 9,927,269 | 10,035,063 | +107,794 | 7.22 | 9.02 | +1.80 | buy |
| Greenhouse Funds LLLP | 8,220,657 | 8,643,846 | +423,189 | 2.47 | 3.93 | +1.46 | buy |
| D. E. Shaw & Co., Inc. | 3,297,405 | 5,297,528 | +2,000,123 | 0.02 | 0.05 | +0.03 | buy |
| MILLENNIUM MANAGEMENT LLC | 5,974,626 | 5,204,409 | -770,217 | 0.04 | 0.04 | +0.01 | sell |
| STATE STREET CORP | 5,022,251 | 4,978,292 | -43,959 | 0.00 | 0.00 | +0.00 | sell |
| BRAIDWELL LP | 1,771,146 | 4,632,801 | +2,861,655 | 0.41 | 1.74 | +1.34 | buy |
| SCHRODER INVESTMENT MANAGEMENT GROUP | 3,482,003 | 4,017,588 | +535,585 | 0.02 | 0.04 | +0.02 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 3,131,911 | 3,176,644 | +44,733 | 0.00 | 0.00 | +0.00 | buy |
| DRIEHAUS CAPITAL MANAGEMENT LLC | 0 | 2,471,738 | +2,471,738 | 0.00 | 0.20 | +0.20 | buy |
| DIMENSIONAL FUND ADVISORS LP | 3,827,813 | 2,448,747 | -1,379,066 | 0.01 | 0.01 | -0.00 | sell |
| AMERICAN CAPITAL MANAGEMENT INC | 2,345,263 | 2,324,366 | -20,897 | 0.72 | 1.21 | +0.48 | sell |
| GW&K Investment Management, LLC | 2,082,885 | 2,238,767 | +155,882 | 0.14 | 0.23 | +0.09 | buy |
| T. Rowe Price Investment Management, Inc. | 1,305,939 | 2,218,727 | +912,788 | 0.01 | 0.02 | +0.01 | buy |
| MORGAN STANLEY | 2,658,016 | 2,126,049 | -531,967 | 0.00 | 0.00 | +0.00 | sell |
| Aberdeen Group plc | 792,263 | 1,798,939 | +1,006,676 | 0.01 | 0.03 | +0.02 | buy |
| SEGALL BRYANT & HAMILL, LLC | 1,815,949 | 1,732,029 | -83,920 | 0.19 | 0.28 | +0.09 | sell |
| PFM Health Sciences, LP | 2,208,530 | 1,694,051 | -514,479 | 1.45 | 2.02 | +0.56 | sell |
| LOOMIS SAYLES & CO L P | 0 | 1,631,135 | +1,631,135 | 0.00 | 0.02 | +0.02 | buy |
| GOLDMAN SACHS GROUP INC | 1,804,394 | 1,433,130 | -371,264 | 0.00 | 0.00 | +0.00 | sell |
| NORTHERN TRUST CORP | 1,489,681 | 1,423,088 | -66,593 | 0.00 | 0.00 | +0.00 | sell |
| SAMLYN CAPITAL, LLC | 0 | 1,388,221 | +1,388,221 | 0.00 | 0.26 | +0.26 | buy |
| BANK OF AMERICA CORP /DE/ | 1,528,176 | 1,347,726 | -180,450 | 0.00 | 0.00 | +0.00 | sell |
| CITADEL ADVISORS LLC | 2,710,791 | 1,307,471 | -1,403,320 | 0.02 | 0.01 | -0.01 | sell |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 1,132,575 | 1,217,152 | +84,577 | 0.00 | 0.00 | +0.00 | buy |
| NEW YORK STATE COMMON RETIREMENT FUND | 2,196,000 | 1,096,000 | -1,100,000 | 0.00 | 0.00 | -0.00 | sell |
| Trexquant Investment LP | 0 | 885,530 | +885,530 | 0.00 | 0.09 | +0.09 | buy |
| Connor, Clark & Lunn Investment Management Ltd. | 559,306 | 877,949 | +318,643 | 0.01 | 0.03 | +0.01 | buy |
| Bank of New York Mellon Corp | 765,806 | 740,017 | -25,789 | 0.00 | 0.00 | +0.00 | sell |
| PRINCIPAL FINANCIAL GROUP INC | 623,759 | 616,909 | -6,850 | 0.00 | 0.00 | +0.00 | sell |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC | 1,234,870 | 593,790 | -641,080 | 0.03 | 0.02 | -0.01 | sell |
| JPMORGAN CHASE & CO | 818,434 | 584,035 | -234,399 | 0.00 | 0.00 | +0.00 | sell |
| HighMark Wealth Management LLC | 400,334 | 567,334 | +167,000 | 1.36 | 2.72 | +1.36 | buy |
| Invesco Ltd. | 560,373 | 539,157 | -21,216 | 0.00 | 0.00 | +0.00 | sell |
| PUBLIC SECTOR PENSION INVESTMENT BOARD | 503,860 | 447,703 | -56,157 | 0.01 | 0.02 | +0.00 | sell |
| Soleus Capital Management, L.P. | 0 | 427,504 | +427,504 | 0.00 | 0.21 | +0.21 | buy |
| AMERIPRISE FINANCIAL INC | 451,396 | 426,211 | -25,185 | 0.00 | 0.00 | +0.00 | sell |
| Nuveen, LLC | 709,171 | 423,593 | -285,578 | 0.00 | 0.00 | -0.00 | sell |
| RHUMBLINE ADVISERS | 382,655 | 357,256 | -25,399 | 0.00 | 0.00 | +0.00 | sell |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 353,258 | 350,847 | -2,411 | 0.00 | 0.00 | +0.00 | sell |
| UBS Group AG | 804,250 | 347,574 | -456,676 | 0.00 | 0.00 | -0.00 | sell |
| Legal & General Group Plc | 340,598 | 324,189 | -16,409 | 0.00 | 0.00 | +0.00 | sell |
| SG Americas Securities, LLC | 54,270 | 314,371 | +260,101 | 0.00 | 0.00 | +0.00 | buy |
| Samjo Management, LLC | 289,800 | 285,300 | -4,500 | 0.85 | 1.30 | +0.44 | sell |
| VOYA INVESTMENT MANAGEMENT LLC | 23,696 | 284,886 | +261,190 | 0.00 | 0.00 | +0.00 | buy |
| Bellevue Group AG | 370,198 | 278,286 | -91,912 | 0.06 | 0.06 | +0.00 | sell |
| STATE OF WISCONSIN INVESTMENT BOARD | 412,677 | 270,541 | -142,136 | 0.01 | 0.01 | -0.00 | sell |
| Swiss National Bank | 249,500 | 254,700 | +5,200 | 0.00 | 0.00 | +0.00 | buy |
| Bullseye Asset Management LLC | 236,860 | 236,860 | 0 | 0.96 | 1.50 | +0.54 | hold |
| BARCLAYS PLC | 805,555 | 225,178 | -580,377 | 0.00 | 0.00 | -0.00 | sell |
| Allianz Asset Management GmbH | 339,057 | 213,356 | -125,701 | 0.00 | 0.00 | -0.00 | sell |
| TWO SIGMA INVESTMENTS, LP | 0 | 170,900 | +170,900 | 0.00 | 0.00 | +0.00 | buy |
| FMR LLC | 37,128 | 170,487 | +133,359 | 0.00 | 0.00 | +0.00 | buy |
| SILVERBACK ASSET MANAGEMENT LLC | 201,313 | 165,101 | -36,212 | 0.20 | 0.29 | +0.09 | sell |
| FEDERATED HERMES, INC. | 161,663 | 164,148 | +2,485 | 0.00 | 0.00 | +0.00 | buy |
| NEW YORK STATE TEACHERS RETIREMENT SYSTEM | 161,480 | 161,580 | +100 | 0.00 | 0.00 | +0.00 | buy |
| WELLS FARGO & COMPANY/MN | 111,553 | 158,446 | +46,893 | 0.00 | 0.00 | +0.00 | buy |
| TUDOR INVESTMENT CORP ET AL | 375,351 | 156,642 | -218,709 | 0.02 | 0.01 | -0.01 | sell |
| ALLIANCEBERNSTEIN L.P. | 160,340 | 156,254 | -4,086 | 0.00 | 0.00 | +0.00 | sell |
| WHITE PINE CAPITAL LLC | 138,822 | 155,181 | +16,359 | 0.31 | 0.50 | +0.20 | buy |
| AQR CAPITAL MANAGEMENT LLC | 66,004 | 146,352 | +80,348 | 0.00 | 0.00 | +0.00 | buy |
| PERKINS CAPITAL MANAGEMENT INC | 136,850 | 141,850 | +5,000 | 0.93 | 1.32 | +0.39 | buy |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 130,468 | 132,882 | +2,414 | 0.00 | 0.00 | +0.00 | buy |
| PRUDENTIAL FINANCIAL INC | 133,072 | 124,225 | -8,847 | 0.00 | 0.00 | +0.00 | sell |
| PRICE T ROWE ASSOCIATES INC /MD/ | 118,929 | 123,930 | +5,001 | 0.00 | 0.00 | +0.00 | buy |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 118,546 | 123,783 | +5,237 | 0.00 | 0.00 | +0.00 | buy |
| DARK FOREST CAPITAL MANAGEMENT LP | 126,581 | 121,265 | -5,316 | 0.03 | 0.07 | +0.04 | sell |
| GABELLI FUNDS LLC | 119,000 | 119,000 | 0 | 0.01 | 0.01 | +0.00 | hold |
| JANE STREET GROUP, LLC | 362,836 | 114,016 | -248,820 | 0.00 | 0.00 | -0.00 | sell |
| BNP PARIBAS FINANCIAL MARKETS | 472,926 | 112,968 | -359,958 | 0.00 | 0.00 | -0.00 | sell |
| SEI INVESTMENTS CO | 116,961 | 110,820 | -6,141 | 0.00 | 0.00 | +0.00 | sell |
| CANADA LIFE ASSURANCE Co | 150,140 | 106,132 | -44,008 | 0.00 | 0.00 | +0.00 | sell |
| DEUTSCHE BANK AG\ | 108,647 | 104,781 | -3,866 | 0.00 | 0.00 | +0.00 | sell |
| Divisadero Street Capital Management, LP | 15,496 | 100,000 | +84,504 | 0.01 | 0.07 | +0.06 | buy |
| Lighthouse Investment Partners, LLC | 0 | 99,630 | +99,630 | 0.00 | 0.04 | +0.04 | buy |
| MOODY NATIONAL BANK TRUST DIVISION | 90,476 | 90,766 | +290 | 0.06 | 0.10 | +0.04 | buy |
| THRIVENT FINANCIAL FOR LUTHERANS | 93,194 | 88,906 | -4,288 | 0.00 | 0.00 | +0.00 | sell |
| FRANKLIN RESOURCES INC | 1,162,148 | 85,689 | -1,076,459 | 0.00 | 0.00 | -0.00 | sell |
| TWO SIGMA ADVISERS, LP | 0 | 83,600 | +83,600 | 0.00 | 0.00 | +0.00 | buy |
| Y-Intercept (Hong Kong) Ltd | 165,890 | 83,525 | -82,365 | 0.03 | 0.02 | -0.01 | sell |
| Curi Capital, LLC | 83,346 | 83,346 | 0 | 0.01 | 0.02 | +0.01 | hold |
| State of Alaska, Department of Revenue | 71,829 | 73,044 | +1,215 | 0.01 | 0.01 | +0.00 | buy |
| MetLife Investment Management, LLC | 70,210 | 71,734 | +1,524 | 0.00 | 0.00 | +0.00 | buy |
| AMERICAN CENTURY COMPANIES INC | 22,109 | 71,289 | +49,180 | 0.00 | 0.00 | +0.00 | buy |
| PRIVATE MANAGEMENT GROUP INC | 70,000 | 66,000 | -4,000 | 0.00 | 0.00 | -0.00 | sell |
| CHOREO, LLC | 60,149 | 61,462 | +1,313 | 0.01 | 0.01 | +0.00 | buy |
| JANUS HENDERSON GROUP PLC | 60,110 | 60,110 | 0 | 0.00 | 0.00 | +0.00 | hold |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 59,934 | 59,910 | -24 | 0.00 | 0.00 | +0.00 | sell |
| Louisiana State Employees Retirement System | 59,400 | 59,300 | -100 | 0.01 | 0.01 | +0.00 | sell |
| GUIDANCE CAPITAL, INC | 57,739 | 55,869 | -1,870 | 0.16 | 0.18 | +0.02 | sell |
| Creative Planning | 43,939 | 53,966 | +10,027 | 0.00 | 0.00 | +0.00 | buy |
| State of Tennessee, Department of Treasury | 58,082 | 48,658 | -9,424 | 0.00 | 0.00 | +0.00 | sell |
| BARD ASSOCIATES INC | 47,385 | 47,385 | 0 | 0.10 | 0.14 | +0.05 | hold |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 45,410 | 45,410 | 0 | 0.00 | 0.00 | +0.00 | hold |
| EMERALD MUTUAL FUND ADVISERS TRUST | 0 | 44,919 | +44,919 | 0.00 | 0.03 | +0.03 | buy |
| F/m Investments LLC | 0 | 44,919 | +44,919 | 0.00 | 0.02 | +0.02 | buy |
| FULLER & THALER ASSET MANAGEMENT, INC. | 45,830 | 44,780 | -1,050 | 0.00 | 0.00 | +0.00 | sell |
| INTECH INVESTMENT MANAGEMENT LLC | 73,469 | 44,703 | -28,766 | 0.01 | 0.00 | -0.00 | sell |
| Rockefeller Capital Management L.P. | 43,521 | 44,118 | +597 | 0.00 | 0.00 | +0.00 | buy |