| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| VANGUARD GROUP INC | 4,673,678 | 4,683,095 | +9,417 | 0.02 | 0.02 | -0.00 | buy |
| WELLINGTON MANAGEMENT GROUP LLP | 3,794,010 | 3,412,260 | -381,750 | 0.16 | 0.14 | -0.02 | sell |
| Avoro Capital Advisors LLC | 2,858,888 | 2,858,888 | 0 | 8.68 | 7.66 | -1.02 | hold |
| RENAISSANCE TECHNOLOGIES LLC | 2,170,214 | 2,151,714 | -18,500 | 0.74 | 0.78 | +0.04 | sell |
| STATE STREET CORP | 1,947,177 | 1,935,119 | -12,058 | 0.02 | 0.02 | -0.00 | sell |
| FMR LLC | 2,321,040 | 1,017,611 | -1,303,429 | 0.04 | 0.02 | -0.02 | sell |
| AQR CAPITAL MANAGEMENT LLC | 551,767 | 846,955 | +295,188 | 0.23 | 0.33 | +0.10 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 779,762 | 828,271 | +48,509 | 0.02 | 0.02 | -0.00 | buy |
| CITADEL ADVISORS LLC | 77,897 | 719,311 | +641,414 | 0.02 | 0.16 | +0.14 | buy |
| JANUS HENDERSON GROUP PLC | 870,119 | 635,347 | -234,772 | 0.11 | 0.08 | -0.03 | sell |
| FULLER & THALER ASSET MANAGEMENT, INC. | 431,116 | 573,075 | +141,959 | 0.48 | 0.57 | +0.09 | buy |
| DIMENSIONAL FUND ADVISORS LP | 561,950 | 563,286 | +1,336 | 0.04 | 0.04 | -0.00 | buy |
| MORGAN STANLEY | 459,732 | 536,208 | +76,476 | 0.01 | 0.01 | +0.00 | buy |
| LSV ASSET MANAGEMENT | 377,368 | 529,519 | +152,151 | 0.18 | 0.25 | +0.07 | buy |
| ALLIANCEBERNSTEIN L.P. | 104,155 | 473,285 | +369,130 | 0.01 | 0.04 | +0.03 | buy |
| Pacer Advisors, Inc. | 312,799 | 469,594 | +156,795 | 0.19 | 0.25 | +0.05 | buy |
| NORGES BANK | 457,132 | 464,537 | +7,405 | 0.02 | 0.02 | -0.00 | buy |
| Bank of New York Mellon Corp | 553,868 | 458,333 | -95,535 | 0.02 | 0.02 | -0.00 | sell |
| Invesco Ltd. | 225,328 | 442,672 | +217,344 | 0.01 | 0.02 | +0.01 | buy |
| Swedbank AB | 413,167 | 423,630 | +10,463 | 0.15 | 0.85 | +0.70 | buy |
| CAISSE DE DEPOT ET PLACEMENT DU QUEBEC | 280,262 | 420,058 | +139,796 | 0.16 | 0.23 | +0.08 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 319,030 | 398,437 | +79,407 | 0.02 | 0.02 | +0.00 | buy |
| NORTHERN TRUST CORP | 373,794 | 314,111 | -59,683 | 0.01 | 0.01 | -0.00 | sell |
| NORDEA INVESTMENT MANAGEMENT AB | 38,698 | 300,920 | +262,222 | 0.01 | 0.09 | +0.07 | buy |
| FIRST TRUST ADVISORS LP | 287,020 | 295,756 | +8,736 | 0.07 | 0.07 | +0.00 | buy |
| ASSETMARK, INC | 272,316 | 270,162 | -2,154 | 0.22 | 0.20 | -0.01 | sell |
| Palo Alto Investors LP | 395,784 | 267,759 | -128,025 | 7.84 | 6.94 | -0.90 | sell |
| Soleus Capital Management, L.P. | 249,449 | 259,749 | +10,300 | 6.09 | 5.24 | -0.85 | buy |
| CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 256,959 | 256,736 | -223 | 0.04 | 0.04 | -0.00 | sell |
| LOOMIS SAYLES & CO L P | 254,044 | 252,024 | -2,020 | 0.09 | 0.08 | -0.00 | sell |
| Eversept Partners, LP | 246,234 | 251,135 | +4,901 | 5.31 | 4.31 | -1.00 | buy |
| Avidity Partners Management LP | 237,202 | 217,000 | -20,202 | 1.99 | 1.77 | -0.22 | sell |
| PRUDENTIAL FINANCIAL INC | 93,187 | 216,354 | +123,167 | 0.03 | 0.07 | +0.04 | buy |
| SCHRODER INVESTMENT MANAGEMENT GROUP | 187,853 | 216,124 | +28,271 | 0.05 | 0.06 | +0.00 | buy |
| Epoch Investment Partners, Inc. | 213,179 | 213,498 | +319 | 0.21 | 0.22 | +0.00 | buy |
| Legal & General Group Plc | 213,593 | 203,029 | -10,564 | 0.01 | 0.01 | -0.00 | sell |
| Allspring Global Investments Holdings, LLC | 181,397 | 184,934 | +3,537 | 0.07 | 0.07 | +0.00 | buy |
| Qube Research & Technologies Ltd | 205,244 | 184,657 | -20,587 | 0.10 | 0.08 | -0.03 | sell |
| PRINCIPAL FINANCIAL GROUP INC | 178,336 | 182,991 | +4,655 | 0.03 | 0.02 | -0.00 | buy |
| CANADA PENSION PLAN INVESTMENT BOARD | 27,100 | 180,800 | +153,700 | 0.01 | 0.04 | +0.04 | buy |
| Robeco Institutional Asset Management B.V. | 85,073 | 180,066 | +94,993 | 0.05 | 0.09 | +0.04 | buy |
| Eagle Health Investments LP | 170,838 | 179,499 | +8,661 | 7.63 | 7.86 | +0.22 | buy |
| Squarepoint Ops LLC | 20,180 | 177,501 | +157,321 | 0.02 | 0.17 | +0.15 | buy |
| WEDGE CAPITAL MANAGEMENT L L P/NC | 0 | 170,549 | +170,549 | 0.00 | 0.63 | +0.63 | buy |
| COMERICA BANK | 156,667 | 165,911 | +9,244 | 0.16 | 0.16 | +0.01 | buy |
| Amundi | 189,464 | 165,030 | -24,434 | 0.02 | 0.02 | -0.00 | sell |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 163,415 | 164,622 | +1,207 | 0.01 | 0.01 | -0.00 | buy |
| Point72 Asset Management, L.P. | 0 | 162,700 | +162,700 | 0.00 | 0.11 | +0.11 | buy |
| JPMORGAN CHASE & CO | 177,700 | 156,989 | -20,711 | 0.00 | 0.00 | -0.00 | sell |
| Krensavage Asset Management, LLC | 200,872 | 156,714 | -44,158 | 15.67 | 15.96 | +0.29 | sell |
| Retirement Systems of Alabama | 142,280 | 146,119 | +3,839 | 0.13 | 0.13 | -0.00 | buy |
| VICTORY CAPITAL MANAGEMENT INC | 134,162 | 145,104 | +10,942 | 0.03 | 0.03 | +0.00 | buy |
| Nitorum Capital, L.P. | 121,833 | 144,933 | +23,100 | 2.87 | 3.39 | +0.52 | buy |
| TWO SIGMA INVESTMENTS, LP | 89,579 | 141,086 | +51,507 | 0.05 | 0.08 | +0.03 | buy |
| Swiss National Bank | 146,755 | 140,655 | -6,100 | 0.02 | 0.02 | -0.00 | sell |
| CITIGROUP INC | 84,196 | 140,164 | +55,968 | 0.02 | 0.03 | +0.01 | buy |
| RHUMBLINE ADVISERS | 137,842 | 137,743 | -99 | 0.03 | 0.03 | -0.00 | sell |
| DEUTSCHE BANK AG\ | 153,595 | 130,986 | -22,609 | 0.02 | 0.01 | -0.00 | sell |
| Polaris Capital Management, LLC | 142,550 | 129,950 | -12,600 | 1.51 | 1.49 | -0.03 | sell |
| Parkman Healthcare Partners LLC | 161,539 | 128,199 | -33,340 | 5.03 | 3.61 | -1.41 | sell |
| MARSHALL WACE, LLP | 9,855 | 125,643 | +115,788 | 0.00 | 0.05 | +0.04 | buy |
| BANK OF AMERICA CORP /DE/ | 73,132 | 121,516 | +48,384 | 0.00 | 0.00 | +0.00 | buy |
| Pictet Asset Management Holding SA | 153,183 | 121,079 | -32,104 | 0.04 | 0.03 | -0.01 | sell |
| APG Asset Management N.V. | 101,362 | 118,242 | +16,880 | 0.04 | 0.04 | +0.00 | buy |
| HSBC HOLDINGS PLC | 94,693 | 116,758 | +22,065 | 0.02 | 0.02 | -0.00 | buy |
| LAZARD ASSET MANAGEMENT LLC | 197,073 | 115,251 | -81,822 | 0.05 | 0.03 | -0.02 | sell |
| Clark Capital Management Group, Inc. | 111,575 | 114,595 | +3,020 | 0.20 | 0.20 | -0.00 | buy |
| TWO SIGMA ADVISERS, LP | 16,601 | 113,401 | +96,800 | 0.01 | 0.06 | +0.05 | buy |
| ACADIAN ASSET MANAGEMENT LLC | 31,478 | 111,956 | +80,478 | 0.03 | 0.09 | +0.06 | buy |
| Portolan Capital Management, LLC | 91,808 | 110,922 | +19,114 | 1.77 | 1.94 | +0.18 | buy |
| FARALLON CAPITAL MANAGEMENT LLC | 476,000 | 110,000 | -366,000 | 0.65 | 0.15 | -0.51 | sell |
| TOBAM | 113,757 | 108,647 | -5,110 | 2.19 | 2.24 | +0.05 | sell |
| Man Group plc | 34,840 | 106,521 | +71,681 | 0.02 | 0.07 | +0.04 | buy |
| Sumitomo Mitsui Trust Group, Inc. | 100,704 | 101,042 | +338 | 0.02 | 0.02 | -0.00 | buy |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | 10,165 | 97,949 | +87,784 | 0.00 | 0.02 | +0.02 | buy |
| DekaBank Deutsche Girozentrale | 94,643 | 93,165 | -1,478 | 0.04 | 0.04 | -0.00 | sell |
| BARCLAYS PLC | 107,072 | 90,871 | -16,201 | 0.01 | 0.01 | -0.00 | sell |
| LOS ANGELES CAPITAL MANAGEMENT LLC | 73,405 | 88,852 | +15,447 | 0.06 | 0.07 | +0.01 | buy |
| Schonfeld Strategic Advisors LLC | 84,595 | 85,623 | +1,028 | 0.15 | 0.15 | +0.00 | buy |
| TD ASSET MANAGEMENT INC | 82,951 | 81,537 | -1,414 | 0.02 | 0.02 | -0.00 | sell |
| Assenagon Asset Management S.A. | 78,002 | 80,907 | +2,905 | 0.05 | 0.05 | -0.00 | buy |
| UBS Group AG | 64,674 | 79,637 | +14,963 | 0.01 | 0.01 | +0.00 | buy |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 73,248 | 74,773 | +1,525 | 0.02 | 0.02 | -0.00 | buy |
| Summit Global Investments | 27,112 | 73,670 | +46,558 | 0.39 | 1.26 | +0.87 | buy |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 39,793 | 71,943 | +32,150 | 0.01 | 0.02 | +0.01 | buy |
| BANK OF MONTREAL /CAN/ | 50,529 | 71,649 | +21,120 | 0.00 | 0.01 | +0.00 | buy |
| BANK OF NOVA SCOTIA | 24,879 | 71,638 | +46,759 | 0.01 | 0.03 | +0.02 | buy |
| AMERIPRISE FINANCIAL INC | 73,033 | 70,996 | -2,037 | 0.00 | 0.00 | -0.00 | sell |
| ATWOOD & PALMER INC | 59,872 | 63,597 | +3,725 | 1.06 | 1.11 | +0.04 | buy |
| WELLS FARGO & COMPANY/MN | 47,224 | 63,463 | +16,239 | 0.00 | 0.00 | +0.00 | buy |
| Russell Investments Group, Ltd. | 79,931 | 63,398 | -16,533 | 0.03 | 0.02 | -0.01 | sell |
| AMERICAN INTERNATIONAL GROUP, INC. | 63,381 | 62,192 | -1,189 | 0.06 | 0.05 | -0.01 | sell |
| WORLDQUANT MILLENNIUM ADVISORS LLC | 62,221 | 59,426 | -2,795 | 0.19 | 0.17 | -0.02 | sell |
| Skandinaviska Enskilda Banken AB (publ) | 57,694 | 59,178 | +1,484 | 0.07 | 0.07 | -0.01 | buy |
| GLOBEFLEX CAPITAL L P | 58,927 | 58,927 | 0 | 1.32 | 1.32 | -0.00 | hold |
| GOLDMAN SACHS GROUP INC | 106,129 | 58,476 | -47,653 | 0.00 | 0.00 | -0.00 | sell |
| AXA S.A. | 53,371 | 56,832 | +3,461 | 0.04 | 0.04 | +0.00 | buy |
| NEW YORK STATE TEACHERS RETIREMENT SYSTEM | 54,533 | 55,770 | +1,237 | 0.03 | 0.03 | -0.00 | buy |
| CANADA LIFE ASSURANCE Co | 58,883 | 55,664 | -3,219 | 0.03 | 0.03 | -0.00 | sell |
| SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC | 0 | 54,705 | +54,705 | 0.00 | 0.59 | +0.59 | buy |