| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| VANGUARD GROUP INC | 4,683,095 | 4,418,963 | -264,132 | 0.02 | 0.03 | +0.01 | sell |
| WELLINGTON MANAGEMENT GROUP LLP | 3,412,260 | 3,285,289 | -126,971 | 0.14 | 0.19 | +0.05 | sell |
| Avoro Capital Advisors LLC | 2,858,888 | 2,858,888 | 0 | 7.66 | 12.13 | +4.47 | hold |
| STATE STREET CORP | 1,935,119 | 2,294,233 | +359,114 | 0.02 | 0.03 | +0.01 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 2,151,714 | 2,174,692 | +22,978 | 0.78 | 1.17 | +0.40 | buy |
| CITIGROUP INC | 140,164 | 1,625,605 | +1,485,441 | 0.03 | 0.50 | +0.46 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 828,271 | 1,048,449 | +220,178 | 0.02 | 0.03 | +0.01 | buy |
| LSV ASSET MANAGEMENT | 529,519 | 966,370 | +436,851 | 0.25 | 0.67 | +0.42 | buy |
| MORGAN STANLEY | 536,208 | 806,988 | +270,780 | 0.01 | 0.02 | +0.01 | buy |
| FMR LLC | 1,017,611 | 763,624 | -253,987 | 0.02 | 0.02 | -0.00 | sell |
| AQR CAPITAL MANAGEMENT LLC | 846,955 | 719,510 | -127,445 | 0.33 | 0.35 | +0.02 | sell |
| DIMENSIONAL FUND ADVISORS LP | 563,286 | 585,969 | +22,683 | 0.04 | 0.05 | +0.01 | buy |
| FULLER & THALER ASSET MANAGEMENT, INC. | 573,075 | 574,976 | +1,901 | 0.57 | 0.78 | +0.21 | buy |
| Pacer Advisors, Inc. | 469,594 | 561,834 | +92,240 | 0.25 | 0.41 | +0.16 | buy |
| ALLIANCEBERNSTEIN L.P. | 473,285 | 539,617 | +66,332 | 0.04 | 0.06 | +0.02 | buy |
| Amundi | 165,030 | 472,992 | +307,962 | 0.02 | 0.06 | +0.04 | buy |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | 97,949 | 438,684 | +340,735 | 0.02 | 0.12 | +0.10 | buy |
| Bank of New York Mellon Corp | 458,333 | 434,839 | -23,494 | 0.02 | 0.03 | +0.01 | sell |
| Swedbank AB | 423,630 | 422,655 | -975 | 0.85 | 0.18 | -0.67 | sell |
| JANUS HENDERSON GROUP PLC | 635,347 | 410,010 | -225,337 | 0.08 | 0.07 | -0.01 | sell |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 398,437 | 387,793 | -10,644 | 0.02 | 0.02 | +0.00 | sell |
| NORTHERN TRUST CORP | 314,111 | 362,730 | +48,619 | 0.01 | 0.02 | +0.01 | buy |
| Invesco Ltd. | 442,672 | 337,203 | -105,469 | 0.02 | 0.02 | +0.00 | sell |
| FIRST TRUST ADVISORS LP | 295,756 | 331,621 | +35,865 | 0.07 | 0.11 | +0.04 | buy |
| Allspring Global Investments Holdings, LLC | 184,934 | 276,531 | +91,597 | 0.07 | 0.14 | +0.08 | buy |
| NORDEA INVESTMENT MANAGEMENT AB | 300,920 | 268,516 | -32,404 | 0.09 | 0.10 | +0.02 | sell |
| ASSETMARK, INC | 270,162 | 267,708 | -2,454 | 0.20 | 0.26 | +0.06 | sell |
| Palo Alto Investors LP | 267,759 | 266,914 | -845 | 6.94 | 9.85 | +2.92 | sell |
| CAISSE DE DEPOT ET PLACEMENT DU QUEBEC | 420,058 | 259,375 | -160,683 | 0.23 | 0.20 | -0.03 | sell |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 164,622 | 243,955 | +79,333 | 0.01 | 0.02 | +0.01 | buy |
| Eversept Partners, LP | 251,135 | 235,351 | -15,784 | 4.31 | 5.74 | +1.43 | sell |
| PRICE T ROWE ASSOCIATES INC /MD/ | 26,976 | 234,916 | +207,940 | 0.00 | 0.01 | +0.01 | buy |
| LOOMIS SAYLES & CO L P | 252,024 | 231,889 | -20,135 | 0.08 | 0.10 | +0.02 | sell |
| SCHRODER INVESTMENT MANAGEMENT GROUP | 216,124 | 226,809 | +10,685 | 0.06 | 0.08 | +0.02 | buy |
| Epoch Investment Partners, Inc. | 213,498 | 226,655 | +13,157 | 0.22 | 0.33 | +0.11 | buy |
| CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 256,736 | 220,282 | -36,454 | 0.04 | 0.05 | +0.01 | sell |
| Robeco Institutional Asset Management B.V. | 180,066 | 189,180 | +9,114 | 0.09 | 0.13 | +0.04 | buy |
| Legal & General Group Plc | 203,029 | 188,862 | -14,167 | 0.01 | 0.02 | +0.00 | sell |
| BANK OF AMERICA CORP /DE/ | 121,516 | 183,897 | +62,381 | 0.00 | 0.01 | +0.00 | buy |
| Clark Capital Management Group, Inc. | 114,595 | 175,913 | +61,318 | 0.20 | 0.41 | +0.22 | buy |
| Eagle Health Investments LP | 179,499 | 167,499 | -12,000 | 7.86 | 9.54 | +1.68 | sell |
| DEUTSCHE BANK AG\ | 130,986 | 162,256 | +31,270 | 0.01 | 0.02 | +0.01 | buy |
| COMERICA BANK | 165,911 | 160,865 | -5,046 | 0.16 | 0.21 | +0.05 | sell |
| KBC Group NV | 3,766 | 158,341 | +154,575 | 0.00 | 0.15 | +0.15 | buy |
| PRINCIPAL FINANCIAL GROUP INC | 182,991 | 157,156 | -25,835 | 0.02 | 0.03 | +0.01 | sell |
| LORD, ABBETT & CO. LLC | 0 | 155,525 | +155,525 | 0.00 | 0.16 | +0.16 | buy |
| VICTORY CAPITAL MANAGEMENT INC | 145,104 | 153,220 | +8,116 | 0.03 | 0.05 | +0.02 | buy |
| Polaris Capital Management, LLC | 129,950 | 148,550 | +18,600 | 1.49 | 2.54 | +1.05 | buy |
| FARALLON CAPITAL MANAGEMENT LLC | 110,000 | 143,000 | +33,000 | 0.15 | 0.27 | +0.12 | buy |
| JPMORGAN CHASE & CO | 156,989 | 142,255 | -14,734 | 0.00 | 0.00 | +0.00 | sell |
| Retirement Systems of Alabama | 146,119 | 141,853 | -4,266 | 0.13 | 0.17 | +0.04 | sell |
| Soleus Capital Management, L.P. | 259,749 | 141,499 | -118,250 | 5.24 | 3.97 | -1.27 | sell |
| Nitorum Capital, L.P. | 144,933 | 140,822 | -4,111 | 3.39 | 4.89 | +1.50 | sell |
| Swiss National Bank | 140,655 | 132,355 | -8,300 | 0.02 | 0.03 | +0.01 | sell |
| RHUMBLINE ADVISERS | 137,743 | 130,842 | -6,901 | 0.03 | 0.04 | +0.01 | sell |
| WEDGE CAPITAL MANAGEMENT L L P/NC | 170,549 | 126,809 | -43,740 | 0.63 | 0.72 | +0.08 | sell |
| FRANKLIN RESOURCES INC | 38,922 | 126,790 | +87,868 | 0.00 | 0.01 | +0.01 | buy |
| Krensavage Asset Management, LLC | 156,714 | 118,208 | -38,506 | 15.96 | 17.29 | +1.33 | sell |
| TD ASSET MANAGEMENT INC | 81,537 | 113,782 | +32,245 | 0.02 | 0.03 | +0.02 | buy |
| Parkman Healthcare Partners LLC | 128,199 | 111,381 | -16,818 | 3.61 | 4.83 | +1.22 | sell |
| Avidity Partners Management LP | 217,000 | 110,000 | -107,000 | 1.77 | 1.49 | -0.28 | sell |
| LAZARD ASSET MANAGEMENT LLC | 115,251 | 105,694 | -9,557 | 0.03 | 0.04 | +0.01 | sell |
| MILLENNIUM MANAGEMENT LLC | 43,677 | 103,031 | +59,354 | 0.01 | 0.03 | +0.02 | buy |
| APG Asset Management N.V. | 118,242 | 100,638 | -17,604 | 0.04 | 0.05 | +0.01 | sell |
| Sumitomo Mitsui Trust Group, Inc. | 101,042 | 99,834 | -1,208 | 0.02 | 0.02 | +0.01 | sell |
| LOS ANGELES CAPITAL MANAGEMENT LLC | 88,852 | 99,328 | +10,476 | 0.07 | 0.11 | +0.04 | buy |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 71,943 | 98,783 | +26,840 | 0.02 | 0.03 | +0.01 | buy |
| DekaBank Deutsche Girozentrale | 93,165 | 94,975 | +1,810 | 0.04 | 0.05 | +0.01 | buy |
| Assenagon Asset Management S.A. | 80,907 | 90,580 | +9,673 | 0.05 | 0.07 | +0.02 | buy |
| Skandinaviska Enskilda Banken AB (publ) | 59,178 | 87,370 | +28,192 | 0.07 | 0.13 | +0.07 | buy |
| WELLS FARGO & COMPANY/MN | 63,463 | 85,147 | +21,684 | 0.00 | 0.01 | +0.00 | buy |
| National Pension Service | 0 | 82,300 | +82,300 | 0.00 | 0.03 | +0.03 | buy |
| UBS Group AG | 79,637 | 81,776 | +2,139 | 0.01 | 0.01 | +0.00 | buy |
| GOLDMAN SACHS GROUP INC | 58,476 | 80,710 | +22,234 | 0.00 | 0.01 | +0.00 | buy |
| BI Asset Management Fondsmaeglerselskab A/S | 24,573 | 75,669 | +51,096 | 0.11 | 0.39 | +0.29 | buy |
| Man Group plc | 106,521 | 75,319 | -31,202 | 0.07 | 0.06 | -0.00 | sell |
| BARCLAYS PLC | 90,871 | 74,039 | -16,832 | 0.01 | 0.01 | +0.00 | sell |
| AMERIPRISE FINANCIAL INC | 70,996 | 73,297 | +2,301 | 0.00 | 0.01 | +0.00 | buy |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 74,773 | 72,764 | -2,009 | 0.02 | 0.03 | +0.01 | sell |
| EVENTIDE ASSET MANAGEMENT, LLC | 0 | 67,825 | +67,825 | 0.00 | 0.37 | +0.37 | buy |
| Railway Pension Investments Ltd | 9,700 | 66,200 | +56,500 | 0.02 | 0.25 | +0.23 | buy |
| Rafferty Asset Management, LLC | 37,730 | 65,443 | +27,713 | 0.03 | 0.08 | +0.05 | buy |
| CANADA LIFE ASSURANCE Co | 55,664 | 65,335 | +9,671 | 0.03 | 0.04 | +0.01 | buy |
| AXA S.A. | 56,832 | 65,040 | +8,208 | 0.04 | 0.06 | +0.02 | buy |
| Candriam S.C.A. | 2,940 | 64,513 | +61,573 | 0.00 | 0.12 | +0.12 | buy |
| ATWOOD & PALMER INC | 63,597 | 63,762 | +165 | 1.11 | 1.54 | +0.43 | buy |
| HSBC HOLDINGS PLC | 116,758 | 62,861 | -53,897 | 0.02 | 0.01 | -0.01 | sell |
| Russell Investments Group, Ltd. | 63,398 | 62,508 | -890 | 0.02 | 0.03 | +0.01 | sell |
| GLOBEFLEX CAPITAL L P | 58,927 | 60,924 | +1,997 | 1.32 | 2.03 | +0.71 | buy |
| PRUDENTIAL FINANCIAL INC | 216,354 | 59,479 | -156,875 | 0.07 | 0.03 | -0.04 | sell |
| Pictet Asset Management Holding SA | 121,079 | 57,512 | -63,567 | 0.03 | 0.02 | -0.01 | sell |
| TOBAM | 108,647 | 56,258 | -52,389 | 2.24 | 2.81 | +0.57 | sell |
| NEW YORK STATE TEACHERS RETIREMENT SYSTEM | 55,770 | 55,804 | +34 | 0.03 | 0.04 | +0.01 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 35,807 | 55,608 | +19,801 | 0.01 | 0.02 | +0.01 | buy |
| Portolan Capital Management, LLC | 110,922 | 54,845 | -56,077 | 1.94 | 1.44 | -0.50 | sell |
| SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC | 54,705 | 54,235 | -470 | 0.59 | 0.40 | -0.19 | sell |
| Summit Global Investments | 73,670 | 53,671 | -19,999 | 1.26 | 1.15 | -0.10 | sell |
| Connor, Clark & Lunn Investment Management Ltd. | 5,392 | 53,497 | +48,105 | 0.01 | 0.07 | +0.07 | buy |
| Mitsubishi UFJ Trust & Banking Corp | 35,794 | 52,714 | +16,920 | 0.02 | 0.04 | +0.02 | buy |
| Tri Locum Partners LP | 0 | 50,100 | +50,100 | 0.00 | 4.04 | +4.04 | buy |