| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Vivo Capital, LLC | 0 | 11,800,000 | +11,800,000 | 0.00 | 6.00 | +6.00 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 0 | 1,312,520 | +1,312,520 | 0.00 | 0.00 | +0.00 | buy |
| STATE STREET CORP | 0 | 160,875 | +160,875 | 0.00 | 0.00 | +0.00 | buy |
| Skandinaviska Enskilda Banken AB (publ) | 0 | 40,000 | +40,000 | 0.00 | 0.00 | 0.00 | buy |
| Spark Investment Management LLC | 0 | 29,100 | +29,100 | 0.00 | 0.00 | 0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 0 | 27,717 | +27,717 | 0.00 | 0.00 | +0.00 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 0 | 16,430 | +16,430 | 0.00 | 0.00 | +0.00 | buy |
| WELLS FARGO & COMPANY/MN | 0 | 12,750 | +12,750 | 0.00 | 0.00 | +0.00 | buy |
| YHB Investment Advisors, Inc. | 0 | 1,200 | +1,200 | 0.00 | 0.00 | 0.00 | buy |
| Atlantic Edge Private Wealth Management, LLC | 0 | 1,000 | +1,000 | 0.00 | 0.00 | 0.00 | buy |
| NAVELLIER & ASSOCIATES INC | 13,641 | 14,288 | +647 | 0.00 | 0.00 | 0.00 | buy |
| Clearstead Advisors, LLC | 0 | 500 | +500 | 0.00 | 0.00 | 0.00 | buy |
| GROUP ONE TRADING LLC | 0 | 412 | +412 | 0.00 | 0.00 | +0.00 | buy |
| EverSource Wealth Advisors, LLC | 0 | 4 | +4 | 0.00 | 0.00 | 0.00 | buy |
| ORBIMED ADVISORS LLC | 2,718,735 | 2,718,735 | 0 | 6.81 | 6.24 | -0.57 | hold |
| ASSETMARK, INC | 13 | 13 | 0 | 0.00 | 0.00 | 0.00 | hold |
| Transamerica Financial Advisors, LLC | 2 | 2 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Horizon Investments, LLC | 52 | 52 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Neumann Advisory Hong Kong Ltd | 315,586 | 315,586 | 0 | 0.78 | 1.00 | +0.22 | hold |
| CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 68,732 | 68,732 | 0 | 0.00 | 0.00 | 0.00 | hold |