| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| BlackRock, Inc. | 12,151,276 | 12,432,023 | +280,747 | 0.01 | 0.02 | +0.01 | buy |
| INGALLS & SNYDER LLC | 7,608,716 | 7,934,507 | +325,791 | 10.89 | 18.85 | +7.96 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 5,682,783 | 5,261,628 | -421,155 | 0.36 | 0.63 | +0.27 | sell |
| Parallel Advisors, LLC | 3,977,404 | 3,962,177 | -15,227 | 2.89 | 5.26 | +2.37 | sell |
| FMR LLC | 3,190,192 | 3,337,618 | +147,426 | 0.01 | 0.01 | +0.01 | buy |
| STATE STREET CORP | 3,200,946 | 3,279,381 | +78,435 | 0.00 | 0.01 | +0.00 | buy |
| AQR CAPITAL MANAGEMENT LLC | 406,205 | 2,582,561 | +2,176,356 | 0.01 | 0.08 | +0.07 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 2,713,519 | 2,532,198 | -181,321 | 0.01 | 0.01 | +0.00 | sell |
| FIRST TRUST ADVISORS LP | 2,173,376 | 1,829,545 | -343,831 | 0.06 | 0.09 | +0.03 | sell |
| TANG CAPITAL MANAGEMENT LLC | 1,500,000 | 1,500,000 | 0 | 3.07 | 5.92 | +2.85 | hold |
| UBS Group AG | 1,363,668 | 1,377,658 | +13,990 | 0.01 | 0.02 | +0.01 | buy |
| DIMENSIONAL FUND ADVISORS LP | 1,553,135 | 1,318,821 | -234,314 | 0.01 | 0.02 | +0.01 | sell |
| Sixth Street Partners Management Company, L.P. | 0 | 1,157,580 | +1,157,580 | 0.00 | 0.01 | +0.01 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 1,119,959 | 1,157,580 | +37,621 | 0.01 | 0.01 | +0.01 | buy |
| MORGAN STANLEY | 1,018,845 | 1,137,559 | +118,714 | 0.00 | 0.01 | +0.00 | buy |
| D. E. Shaw & Co., Inc. | 1,181,348 | 883,001 | -298,347 | 0.04 | 0.05 | +0.01 | sell |
| Cerity Partners LLC | 731,689 | 797,119 | +65,430 | 0.04 | 0.08 | +0.04 | buy |
| MPM BioImpact LLC | 985,700 | 771,028 | -214,672 | 3.07 | 4.09 | +1.02 | sell |
| NORTHERN TRUST CORP | 643,158 | 753,796 | +110,638 | 0.00 | 0.01 | +0.00 | buy |
| EMERALD ADVISERS, LLC | 205,558 | 748,325 | +542,767 | 0.26 | 1.53 | +1.27 | buy |
| FULLER & THALER ASSET MANAGEMENT, INC. | 0 | 710,106 | +710,106 | 0.00 | 0.17 | +0.17 | buy |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 0 | 695,532 | +695,532 | 0.00 | 0.22 | +0.22 | buy |
| TWO SIGMA INVESTMENTS, LP | 945,884 | 610,078 | -335,806 | 0.03 | 0.04 | +0.01 | sell |
| GOLDMAN SACHS GROUP INC | 725,822 | 568,519 | -157,303 | 0.00 | 0.01 | +0.00 | sell |
| Bank of New York Mellon Corp | 543,757 | 565,666 | +21,909 | 0.00 | 0.01 | +0.00 | buy |
| Invesco Ltd. | 628,384 | 523,669 | -104,715 | 0.00 | 0.00 | +0.00 | sell |
| Allspring Global Investments Holdings, LLC | 214,572 | 523,192 | +308,620 | 0.02 | 0.07 | +0.06 | buy |
| NORGES BANK | 0 | 487,055 | +487,055 | 0.00 | 0.00 | +0.00 | buy |
| EMERALD MUTUAL FUND ADVISERS TRUST | 179,607 | 464,902 | +285,295 | 0.35 | 1.42 | +1.07 | buy |
| PRINCIPAL FINANCIAL GROUP INC | 455,248 | 459,742 | +4,494 | 0.01 | 0.02 | +0.01 | buy |
| Boston Trust Walden Corp | 462,606 | 440,264 | -22,342 | 0.15 | 0.29 | +0.14 | sell |
| PERCEPTIVE ADVISORS LLC | 50,000 | 398,385 | +348,385 | 0.04 | 0.54 | +0.50 | buy |
| Nuveen, LLC | 191,904 | 388,078 | +196,174 | 0.00 | 0.01 | +0.01 | buy |
| Boxer Capital Management, LLC | 250,000 | 335,500 | +85,500 | 1.32 | 2.20 | +0.87 | buy |
| BANK OF AMERICA CORP /DE/ | 111,736 | 328,565 | +216,829 | 0.00 | 0.00 | +0.00 | buy |
| PUBLIC SECTOR PENSION INVESTMENT BOARD | 334,875 | 328,224 | -6,651 | 0.04 | 0.07 | +0.03 | sell |
| FAS Wealth Partners, Inc. | 322,370 | 324,876 | +2,506 | 0.81 | 1.47 | +0.66 | buy |
| JPMORGAN CHASE & CO | 200,953 | 253,182 | +52,229 | 0.00 | 0.00 | +0.00 | buy |
| Legal & General Group Plc | 219,680 | 218,078 | -1,602 | 0.00 | 0.00 | +0.00 | sell |
| AMERIPRISE FINANCIAL INC | 212,074 | 212,162 | +88 | 0.00 | 0.00 | +0.00 | buy |
| FRANKLIN RESOURCES INC | 305,211 | 212,029 | -93,182 | 0.00 | 0.00 | +0.00 | sell |
| Susquehanna Portfolio Strategies, LLC | 177,147 | 211,017 | +33,870 | 0.11 | 0.29 | +0.19 | buy |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 217,468 | 202,743 | -14,725 | 0.00 | 0.00 | +0.00 | sell |
| KENNEDY CAPITAL MANAGEMENT LLC | 304,615 | 201,979 | -102,636 | 0.26 | 0.31 | +0.05 | sell |
| Swiss National Bank | 186,965 | 192,165 | +5,200 | 0.00 | 0.01 | +0.00 | buy |
| CANADA PENSION PLAN INVESTMENT BOARD | 324,901 | 191,101 | -133,800 | 0.01 | 0.01 | +0.00 | sell |
| RHUMBLINE ADVISERS | 190,698 | 187,772 | -2,926 | 0.01 | 0.01 | +0.01 | sell |
| CAPITAL FUND MANAGEMENT S.A. | 126,429 | 184,231 | +57,802 | 0.05 | 0.11 | +0.07 | buy |
| Russell Investments Group, Ltd. | 13,128 | 177,770 | +164,642 | 0.00 | 0.01 | +0.01 | buy |
| Granite Investment Partners, LLC | 0 | 172,228 | +172,228 | 0.00 | 0.77 | +0.77 | buy |
| HRT FINANCIAL LP | 72,853 | 168,678 | +95,825 | 0.01 | 0.03 | +0.02 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 86,590 | 165,235 | +78,645 | 0.00 | 0.00 | +0.00 | buy |
| MILLENNIUM MANAGEMENT LLC | 558,747 | 152,567 | -406,180 | 0.02 | 0.01 | -0.01 | sell |
| CITIGROUP INC | 421,067 | 141,809 | -279,258 | 0.01 | 0.01 | -0.01 | sell |
| LPL Financial LLC | 134,309 | 139,389 | +5,080 | 0.00 | 0.00 | +0.00 | buy |
| VAN ECK ASSOCIATES CORP | 159,550 | 139,135 | -20,415 | 0.00 | 0.01 | +0.00 | sell |
| BARCLAYS PLC | 172,078 | 137,033 | -35,045 | 0.00 | 0.00 | +0.00 | sell |
| Propel Bio Management, LLC | 147,828 | 136,499 | -11,329 | 3.80 | 6.21 | +2.42 | sell |
| ROYCE & ASSOCIATES LP | 135,430 | 133,300 | -2,130 | 0.05 | 0.09 | +0.04 | sell |
| Rockefeller Capital Management L.P. | 123,497 | 123,388 | -109 | 0.01 | 0.02 | +0.01 | sell |
| Livforsakringsbolaget Skandia, Omsesidigt | 805 | 114,100 | +113,295 | 0.01 | 0.07 | +0.06 | buy |
| Alberta Investment Management Corp | 0 | 113,200 | +113,200 | 0.00 | 0.06 | +0.06 | buy |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 110,829 | 110,545 | -284 | 0.00 | 0.01 | +0.00 | sell |
| NATIXIS | 81 | 109,905 | +109,824 | 0.00 | 0.05 | +0.05 | buy |
| CITADEL ADVISORS LLC | 254,220 | 109,105 | -145,115 | 0.01 | 0.01 | -0.00 | sell |
| MERCER GLOBAL ADVISORS INC /ADV | 80,018 | 102,823 | +22,805 | 0.00 | 0.01 | +0.01 | buy |
| Walleye Capital LLC | 1,000 | 99,847 | +98,847 | 0.00 | 0.04 | +0.04 | buy |
| PRUDENTIAL FINANCIAL INC | 92,534 | 99,761 | +7,227 | 0.00 | 0.01 | +0.00 | buy |
| NEW YORK STATE COMMON RETIREMENT FUND | 64,988 | 98,803 | +33,815 | 0.00 | 0.01 | +0.01 | buy |
| O'Neil Global Advisors, Inc. | 0 | 98,334 | +98,334 | 0.00 | 1.91 | +1.91 | buy |
| IEQ CAPITAL, LLC | 0 | 92,394 | +92,394 | 0.00 | 0.04 | +0.04 | buy |
| Voleon Capital Management LP | 262,223 | 91,926 | -170,297 | 0.23 | 0.15 | -0.08 | sell |
| Lisanti Capital Growth, LLC | 0 | 91,610 | +91,610 | 0.00 | 1.75 | +1.75 | buy |
| KBC Group NV | 94,767 | 91,584 | -3,183 | 0.01 | 0.02 | +0.01 | sell |
| Mariner, LLC | 6,006 | 89,838 | +83,832 | 0.00 | 0.01 | +0.01 | buy |
| Allianz Asset Management GmbH | 89,152 | 89,152 | 0 | 0.00 | 0.01 | +0.00 | hold |
| F/m Investments LLC | 51,152 | 88,042 | +36,890 | 0.14 | 0.39 | +0.25 | buy |
| RAYMOND JAMES FINANCIAL INC | 27,540 | 85,624 | +58,084 | 0.00 | 0.00 | +0.00 | buy |
| NEW YORK STATE TEACHERS RETIREMENT SYSTEM | 103,521 | 85,579 | -17,942 | 0.01 | 0.01 | +0.01 | sell |
| BROWN CAPITAL MANAGEMENT LLC | 93,693 | 84,041 | -9,652 | 0.54 | 1.46 | +0.92 | sell |
| KORNITZER CAPITAL MANAGEMENT INC /KS | 0 | 83,110 | +83,110 | 0.00 | 0.15 | +0.15 | buy |
| Creative Planning | 36,789 | 82,301 | +45,512 | 0.00 | 0.00 | +0.00 | buy |
| Connor, Clark & Lunn Investment Management Ltd. | 117,954 | 81,569 | -36,385 | 0.01 | 0.01 | +0.00 | sell |
| ENVESTNET ASSET MANAGEMENT INC | 41,860 | 76,626 | +34,766 | 0.00 | 0.00 | +0.00 | buy |
| BESSEMER GROUP INC | 76,617 | 76,446 | -171 | 0.00 | 0.01 | +0.00 | sell |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | 0 | 76,278 | +76,278 | 0.00 | 0.01 | +0.01 | buy |
| CANADA LIFE ASSURANCE Co | 76,342 | 74,986 | -1,356 | 0.01 | 0.01 | +0.00 | sell |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | 72,407 | 73,222 | +815 | 0.01 | 0.01 | +0.01 | buy |
| STATE OF WISCONSIN INVESTMENT BOARD | 59,470 | 72,200 | +12,730 | 0.01 | 0.01 | +0.01 | buy |
| Rock Springs Capital Management LP | 50,250 | 72,000 | +21,750 | 0.12 | 0.31 | +0.19 | buy |
| Man Group plc | 77,604 | 71,491 | -6,113 | 0.01 | 0.01 | +0.00 | sell |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 230,731 | 69,684 | -161,047 | 0.01 | 0.01 | -0.01 | sell |
| Stanley-Laman Group, Ltd. | 68,625 | 68,196 | -429 | 0.34 | 0.60 | +0.26 | sell |
| SEI INVESTMENTS CO | 32,379 | 67,711 | +35,332 | 0.00 | 0.01 | +0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 139,257 | 64,569 | -74,688 | 0.00 | 0.00 | -0.00 | sell |
| THRIVENT FINANCIAL FOR LUTHERANS | 62,487 | 62,740 | +253 | 0.00 | 0.01 | +0.00 | buy |
| Gotham Asset Management, LLC | 17,918 | 60,181 | +42,263 | 0.00 | 0.01 | +0.01 | buy |
| Bridgewater Associates, LP | 38,422 | 57,602 | +19,180 | 0.01 | 0.02 | +0.01 | buy |
| Birchview Capital, LP | 47,200 | 57,200 | +10,000 | 1.08 | 2.33 | +1.24 | buy |
| S&T BANK/PA | 68,087 | 55,553 | -12,534 | 1.02 | 1.45 | +0.42 | sell |