| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | 3,916,825 | 3,743,018 | -173,807 | 2.23 | 1.71 | -0.52 | sell |
| BlackRock, Inc. | 2,787,308 | 2,971,650 | +184,342 | 0.00 | 0.00 | -0.00 | buy |
| VANGUARD GROUP INC | 2,287,084 | 2,383,548 | +96,464 | 0.00 | 0.00 | -0.00 | buy |
| BANK OF AMERICA CORP /DE/ | 1,746,186 | 2,159,923 | +413,737 | 0.01 | 0.01 | -0.00 | buy |
| Artisan Partners Limited Partnership | 1,170,231 | 1,551,620 | +381,389 | 0.09 | 0.08 | -0.00 | buy |
| FMR LLC | 1,202,251 | 1,093,776 | -108,475 | 0.00 | 0.00 | -0.00 | sell |
| MILLENNIUM MANAGEMENT LLC | 567,468 | 1,007,539 | +440,071 | 0.02 | 0.03 | +0.01 | buy |
| CITADEL ADVISORS LLC | 211,743 | 994,167 | +782,424 | 0.01 | 0.03 | +0.02 | buy |
| STATE STREET CORP | 817,671 | 890,799 | +73,128 | 0.00 | 0.00 | -0.00 | buy |
| BROWN CAPITAL MANAGEMENT LLC | 542,437 | 842,192 | +299,755 | 0.58 | 0.67 | +0.09 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 817,117 | 830,758 | +13,641 | 0.00 | 0.00 | -0.00 | buy |
| Divisadero Street Capital Management, LP | 773,640 | 812,535 | +38,895 | 4.92 | 3.49 | -1.43 | buy |
| DEUTSCHE BANK AG\ | 646,590 | 657,224 | +10,634 | 0.01 | 0.01 | -0.00 | buy |
| ROYAL BANK OF CANADA | 15,917 | 508,491 | +492,574 | 0.00 | 0.00 | +0.00 | buy |
| No Street GP LP | 475,000 | 500,000 | +25,000 | 1.81 | 1.16 | -0.65 | buy |
| GILDER GAGNON HOWE & CO LLC | 586,523 | 425,322 | -161,201 | 0.35 | 0.16 | -0.19 | sell |
| Atika Capital Management LLC | 410,600 | 408,600 | -2,000 | 2.17 | 1.82 | -0.35 | sell |
| NORTHERN TRUST CORP | 377,298 | 403,404 | +26,106 | 0.00 | 0.00 | -0.00 | buy |
| BAILLIE GIFFORD & CO | 419,004 | 398,907 | -20,097 | 0.02 | 0.01 | -0.00 | sell |
| MORGAN STANLEY | 486,900 | 392,199 | -94,701 | 0.00 | 0.00 | -0.00 | sell |
| Point72 Asset Management, L.P. | 446,976 | 391,732 | -55,244 | 0.08 | 0.04 | -0.04 | sell |
| Invesco Ltd. | 987,597 | 391,163 | -596,434 | 0.01 | 0.00 | -0.01 | sell |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC | 153,018 | 365,617 | +212,599 | 0.03 | 0.04 | +0.02 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 178,200 | 361,500 | +183,300 | 0.01 | 0.02 | +0.01 | buy |
| DIMENSIONAL FUND ADVISORS LP | 121,267 | 359,144 | +237,877 | 0.00 | 0.00 | +0.00 | buy |
| THRIVENT FINANCIAL FOR LUTHERANS | 229,637 | 352,626 | +122,989 | 0.02 | 0.02 | +0.00 | buy |
| Telemark Asset Management, LLC | 301,000 | 321,000 | +20,000 | 1.50 | 1.10 | -0.40 | buy |
| WASATCH ADVISORS LP | 206,740 | 310,596 | +103,856 | 0.05 | 0.05 | +0.00 | buy |
| Parkman Healthcare Partners LLC | 184,320 | 300,698 | +116,378 | 1.16 | 1.38 | +0.21 | buy |
| NEW YORK STATE COMMON RETIREMENT FUND | 221,711 | 294,051 | +72,340 | 0.01 | 0.01 | -0.00 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 285,329 | 290,754 | +5,425 | 0.00 | 0.00 | -0.00 | buy |
| OSTERWEIS CAPITAL MANAGEMENT INC | 194,245 | 288,072 | +93,827 | 0.49 | 0.46 | -0.03 | buy |
| Altium Capital Management LLC | 112,000 | 285,000 | +173,000 | 1.65 | 3.05 | +1.40 | buy |
| VICTORY CAPITAL MANAGEMENT INC | 259,864 | 271,978 | +12,114 | 0.01 | 0.01 | -0.00 | buy |
| LAZARD ASSET MANAGEMENT LLC | 102,841 | 263,439 | +160,598 | 0.01 | 0.01 | +0.01 | buy |
| Polar Capital Holdings Plc | 184,907 | 224,254 | +39,347 | 0.04 | 0.04 | -0.00 | buy |
| Cubist Systematic Strategies, LLC | 68,670 | 220,028 | +151,358 | 0.05 | 0.12 | +0.07 | buy |
| UBS Group AG | 24,161 | 215,046 | +190,885 | 0.00 | 0.00 | +0.00 | buy |
| Qube Research & Technologies Ltd | 141,668 | 208,943 | +67,275 | 0.01 | 0.01 | -0.00 | buy |
| Schonfeld Strategic Advisors LLC | 0 | 199,400 | +199,400 | 0.00 | 0.04 | +0.04 | buy |
| GOLDMAN SACHS GROUP INC | 132,540 | 196,644 | +64,104 | 0.00 | 0.00 | +0.00 | buy |
| Granite Investment Partners, LLC | 186,234 | 181,331 | -4,903 | 0.39 | 0.27 | -0.12 | sell |
| GREAT LAKES ADVISORS, LLC | 185,146 | 179,345 | -5,801 | 0.08 | 0.05 | -0.02 | sell |
| BNP PARIBAS FINANCIAL MARKETS | 0 | 178,251 | +178,251 | 0.00 | 0.00 | +0.00 | buy |
| NEXT CENTURY GROWTH INVESTORS LLC | 576,453 | 170,899 | -405,554 | 2.31 | 0.44 | -1.87 | sell |
| Circle Wealth Management, LLC | 165,839 | 165,719 | -120 | 0.18 | 0.12 | -0.06 | sell |
| Point72 (DIFC) Ltd | 3,305 | 151,638 | +148,333 | 0.01 | 0.47 | +0.46 | buy |
| Vitruvian Partners LLP | 0 | 144,300 | +144,300 | 0.00 | 4.27 | +4.27 | buy |
| Squarepoint Ops LLC | 118,326 | 133,125 | +14,799 | 0.02 | 0.01 | -0.01 | buy |
| Ensign Peak Advisors, Inc | 104,971 | 132,884 | +27,913 | 0.01 | 0.01 | -0.00 | buy |
| TWO SIGMA ADVISERS, LP | 206,800 | 132,000 | -74,800 | 0.02 | 0.01 | -0.01 | sell |
| TWO SIGMA INVESTMENTS, LP | 282,223 | 127,352 | -154,871 | 0.03 | 0.01 | -0.02 | sell |
| AMERICAN CENTURY COMPANIES INC | 249,562 | 123,805 | -125,757 | 0.01 | 0.00 | -0.00 | sell |
| Granahan Investment Management, LLC | 120,046 | 120,233 | +187 | 0.23 | 0.17 | -0.06 | buy |
| Engineers Gate Manager LP | 93,002 | 106,410 | +13,408 | 0.09 | 0.06 | -0.03 | buy |
| Bank of New York Mellon Corp | 93,497 | 102,882 | +9,385 | 0.00 | 0.00 | -0.00 | buy |
| Sara-Bay Financial | 108,853 | 99,864 | -8,989 | 1.95 | 1.25 | -0.70 | sell |
| Jump Financial, LLC | 59,321 | 93,255 | +33,934 | 0.06 | 0.07 | +0.01 | buy |
| SILVERCREST ASSET MANAGEMENT GROUP LLC | 0 | 86,825 | +86,825 | 0.00 | 0.02 | +0.02 | buy |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 68,818 | 84,958 | +16,140 | 0.00 | 0.00 | -0.00 | buy |
| Grandeur Peak Global Advisors, LLC | 0 | 84,560 | +84,560 | 0.00 | 0.26 | +0.26 | buy |
| ALGERT GLOBAL LLC | 64,148 | 83,530 | +19,382 | 0.09 | 0.07 | -0.02 | buy |
| JANE STREET GROUP, LLC | 36,471 | 83,483 | +47,012 | 0.00 | 0.00 | +0.00 | buy |
| FIRST CITIZENS BANK & TRUST CO | 76,816 | 76,816 | 0 | 0.08 | 0.05 | -0.03 | hold |
| T. Rowe Price Investment Management, Inc. | 76,033 | 73,027 | -3,006 | 0.00 | 0.00 | -0.00 | sell |
| TUDOR INVESTMENT CORP ET AL | 31,469 | 68,138 | +36,669 | 0.02 | 0.02 | +0.01 | buy |
| Swiss National Bank | 64,600 | 66,300 | +1,700 | 0.00 | 0.00 | -0.00 | buy |
| BARCLAYS PLC | 58,786 | 64,807 | +6,021 | 0.00 | 0.00 | -0.00 | buy |
| CITIGROUP INC | 26,841 | 63,595 | +36,754 | 0.00 | 0.00 | +0.00 | buy |
| Trexquant Investment LP | 131,229 | 56,416 | -74,813 | 0.08 | 0.02 | -0.06 | sell |
| AQR CAPITAL MANAGEMENT LLC | 61,196 | 50,151 | -11,045 | 0.00 | 0.00 | -0.00 | sell |
| RHUMBLINE ADVISERS | 46,810 | 48,473 | +1,663 | 0.00 | 0.00 | -0.00 | buy |
| Polar Asset Management Partners Inc. | 0 | 46,700 | +46,700 | 0.00 | 0.02 | +0.02 | buy |
| HRT FINANCIAL LP | 0 | 45,809 | +45,809 | 0.00 | 0.01 | +0.01 | buy |
| Verition Fund Management LLC | 19,673 | 44,580 | +24,907 | 0.01 | 0.01 | +0.00 | buy |
| Nebula Research & Development LLC | 36,423 | 43,201 | +6,778 | 0.22 | 0.17 | -0.04 | buy |
| Legal & General Group Plc | 38,498 | 42,445 | +3,947 | 0.00 | 0.00 | -0.00 | buy |
| FRANKLIN RESOURCES INC | 43,635 | 41,187 | -2,448 | 0.00 | 0.00 | -0.00 | sell |
| FIRST TRUST ADVISORS LP | 108,458 | 40,341 | -68,117 | 0.01 | 0.00 | -0.00 | sell |
| PRINCIPAL FINANCIAL GROUP INC | 36,046 | 39,925 | +3,879 | 0.00 | 0.00 | -0.00 | buy |
| Paragon Advisors, LLC | 31,399 | 37,822 | +6,423 | 0.50 | 0.45 | -0.06 | buy |
| ALLIANCEBERNSTEIN L.P. | 37,100 | 37,100 | 0 | 0.00 | 0.00 | -0.00 | hold |
| SIMPLEX TRADING, LLC | 0 | 34,730 | +34,730 | 0.00 | 0.03 | +0.03 | buy |
| JPMORGAN CHASE & CO | 192,510 | 34,397 | -158,113 | 0.00 | 0.00 | -0.00 | sell |
| Quantbot Technologies LP | 25,403 | 33,444 | +8,041 | 0.05 | 0.04 | -0.01 | buy |
| SEI INVESTMENTS CO | 35,745 | 32,301 | -3,444 | 0.00 | 0.00 | -0.00 | sell |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 31,520 | 31,731 | +211 | 0.00 | 0.00 | -0.00 | buy |
| Walleye Capital LLC | 129,687 | 31,342 | -98,345 | 0.07 | 0.01 | -0.06 | sell |
| FOX RUN MANAGEMENT, L.L.C. | 20,015 | 29,458 | +9,443 | 0.22 | 0.18 | -0.04 | buy |
| Aquatic Capital Management LLC | 28,400 | 29,285 | +885 | 0.04 | 0.03 | -0.01 | buy |
| WELLS FARGO & COMPANY/MN | 26,129 | 26,574 | +445 | 0.00 | 0.00 | -0.00 | buy |
| PDT Partners, LLC | 18,129 | 26,245 | +8,116 | 0.08 | 0.08 | +0.00 | buy |
| LPL Financial LLC | 24,146 | 25,007 | +861 | 0.00 | 0.00 | -0.00 | buy |
| GSA CAPITAL PARTNERS LLP | 21,084 | 24,564 | +3,480 | 0.08 | 0.06 | -0.02 | buy |
| ExodusPoint Capital Management, LP | 17,883 | 24,417 | +6,534 | 0.01 | 0.01 | -0.00 | buy |
| BALYASNY ASSET MANAGEMENT L.P. | 0 | 23,978 | +23,978 | 0.00 | 0.00 | +0.00 | buy |
| Alberta Investment Management Corp | 49,574 | 23,972 | -25,602 | 0.02 | 0.01 | -0.02 | sell |
| STATE OF WISCONSIN INVESTMENT BOARD | 25,661 | 22,946 | -2,715 | 0.00 | 0.00 | -0.00 | sell |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | 22,249 | 22,368 | +119 | 0.00 | 0.00 | -0.00 | buy |
| MetLife Investment Management, LLC | 20,525 | 21,954 | +1,429 | 0.01 | 0.00 | -0.00 | buy |