| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| PRIMECAP MANAGEMENT CO/CA/ | 4,724,991 | 4,612,331 | -112,660 | 0.00 | 0.00 | -0.00 | sell |
| MORGAN STANLEY | 3,993,562 | 2,922,921 | -1,070,641 | 0.00 | 0.00 | -0.00 | sell |
| Soleus Capital Management, L.P. | 2,788,323 | 2,788,323 | 0 | 0.15 | 0.12 | -0.02 | hold |
| ExodusPoint Capital Management, LP | 1,943,834 | 1,223,555 | -720,279 | 0.02 | 0.01 | -0.01 | sell |
| Almitas Capital LLC | 0 | 1,064,202 | +1,064,202 | 0.00 | 0.33 | +0.33 | buy |
| BlackRock, Inc. | 2,661,607 | 882,490 | -1,779,117 | 0.00 | 0.00 | -0.00 | sell |
| Stonepine Capital Management, LLC | 768,288 | 815,436 | +47,148 | 0.87 | 0.81 | -0.06 | buy |
| JANE STREET GROUP, LLC | 0 | 758,231 | +758,231 | 0.00 | 0.00 | +0.00 | buy |
| BRAIDWELL LP | 752,541 | 752,541 | 0 | 0.03 | 0.04 | +0.00 | hold |
| AQR CAPITAL MANAGEMENT LLC | 357,578 | 744,963 | +387,385 | 0.00 | 0.00 | +0.00 | buy |
| Parkman Healthcare Partners LLC | 755,636 | 646,564 | -109,072 | 0.10 | 0.09 | -0.01 | sell |
| GEODE CAPITAL MANAGEMENT, LLC | 944,492 | 452,684 | -491,808 | 0.00 | 0.00 | -0.00 | sell |
| RENAISSANCE TECHNOLOGIES LLC | 320,300 | 425,110 | +104,810 | 0.00 | 0.00 | +0.00 | buy |
| ADAR1 Capital Management, LLC | 374,497 | 404,497 | +30,000 | 0.03 | 0.02 | -0.00 | buy |
| DEUTSCHE BANK AG\ | 1,163,678 | 402,316 | -761,362 | 0.00 | 0.00 | -0.00 | sell |
| D. E. Shaw & Co., Inc. | 335,074 | 327,528 | -7,546 | 0.00 | 0.00 | -0.00 | sell |
| Jefferies Financial Group Inc. | 285,110 | 285,110 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CFM WEALTH PARTNERS LLC | 264,039 | 264,039 | 0 | 0.05 | 0.04 | -0.01 | hold |
| MARSHALL WACE, LLP | 0 | 230,738 | +230,738 | 0.00 | 0.00 | +0.00 | buy |
| ACADIAN ASSET MANAGEMENT LLC | 166,341 | 223,141 | +56,800 | 0.00 | 0.00 | +0.00 | buy |
| MILLENNIUM MANAGEMENT LLC | 0 | 209,556 | +209,556 | 0.00 | 0.00 | +0.00 | buy |
| Birchview Capital, LP | 250,221 | 200,543 | -49,678 | 0.18 | 0.12 | -0.06 | sell |
| Centiva Capital, LP | 153,882 | 200,095 | +46,213 | 0.01 | 0.01 | -0.00 | buy |
| HSBC HOLDINGS PLC | 14,090 | 193,846 | +179,756 | 0.00 | 0.00 | +0.00 | buy |
| STATE STREET CORP | 809,116 | 191,501 | -617,615 | 0.00 | 0.00 | -0.00 | sell |
| Squarepoint Ops LLC | 82,492 | 183,558 | +101,066 | 0.00 | 0.00 | +0.00 | buy |
| GSA CAPITAL PARTNERS LLP | 137,488 | 136,157 | -1,331 | 0.01 | 0.01 | +0.00 | sell |
| XTX Topco Ltd | 80,081 | 118,037 | +37,956 | 0.00 | 0.00 | +0.00 | buy |
| WESTFIELD CAPITAL MANAGEMENT CO LP | 110,000 | 110,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| HRT FINANCIAL LP | 0 | 108,218 | +108,218 | 0.00 | 0.00 | +0.00 | buy |
| BANK OF MONTREAL /CAN/ | 0 | 105,958 | +105,958 | 0.00 | 0.00 | +0.00 | buy |
| NORTHERN TRUST CORP | 354,674 | 104,119 | -250,555 | 0.00 | 0.00 | -0.00 | sell |
| Redhawk Wealth Advisors, Inc. | 34,700 | 99,648 | +64,948 | 0.00 | 0.01 | +0.01 | buy |
| ALGERT GLOBAL LLC | 85,362 | 98,332 | +12,970 | 0.00 | 0.00 | -0.00 | buy |
| DIMENSIONAL FUND ADVISORS LP | 141,920 | 97,791 | -44,129 | 0.00 | 0.00 | -0.00 | sell |
| TWO SIGMA INVESTMENTS, LP | 68,612 | 86,575 | +17,963 | 0.00 | 0.00 | +0.00 | buy |
| IEQ CAPITAL, LLC | 21,587 | 69,158 | +47,571 | 0.00 | 0.00 | +0.00 | buy |
| Quadrature Capital Ltd | 0 | 63,910 | +63,910 | 0.00 | 0.00 | +0.00 | buy |
| Engineers Gate Manager LP | 56,151 | 62,589 | +6,438 | 0.00 | 0.00 | +0.00 | buy |
| MERCER GLOBAL ADVISORS INC /ADV | 48,767 | 61,332 | +12,565 | 0.00 | 0.00 | +0.00 | buy |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 61,000 | 61,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Berger Financial Group, Inc | 54,000 | 54,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| BRIGHTON JONES LLC | 44,733 | 53,231 | +8,498 | 0.00 | 0.00 | +0.00 | buy |
| Schonfeld Strategic Advisors LLC | 49,788 | 50,841 | +1,053 | 0.00 | 0.00 | -0.00 | buy |
| Qube Research & Technologies Ltd | 0 | 49,877 | +49,877 | 0.00 | 0.00 | +0.00 | buy |
| FJARDE AP-FONDEN /FOURTH SWEDISH NATIONAL PENSION FUND | 40,000 | 40,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| PERKINS CAPITAL MANAGEMENT INC | 41,000 | 39,500 | -1,500 | 0.05 | 0.04 | -0.01 | sell |
| Mariner, LLC | 11,067 | 38,530 | +27,463 | 0.00 | 0.00 | +0.00 | buy |
| Cerity Partners LLC | 28,836 | 38,143 | +9,307 | 0.00 | 0.00 | +0.00 | buy |
| FMR LLC | 48,222 | 35,728 | -12,494 | 0.00 | 0.00 | -0.00 | sell |
| Jain Global LLC | 0 | 34,995 | +34,995 | 0.00 | 0.00 | +0.00 | buy |
| BARCLAYS PLC | 683,435 | 34,138 | -649,297 | 0.00 | 0.00 | -0.00 | sell |
| Creative Planning | 22,731 | 33,509 | +10,778 | 0.00 | 0.00 | +0.00 | buy |
| Virtu Financial LLC | 0 | 29,454 | +29,454 | 0.00 | 0.00 | +0.00 | buy |
| R Squared Ltd | 19,780 | 27,429 | +7,649 | 0.01 | 0.02 | +0.00 | buy |
| SEI INVESTMENTS CO | 24,303 | 23,677 | -626 | 0.00 | 0.00 | -0.00 | sell |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | 0 | 23,233 | +23,233 | 0.00 | 0.00 | +0.00 | buy |
| RHUMBLINE ADVISERS | 46,380 | 19,383 | -26,997 | 0.00 | 0.00 | -0.00 | sell |
| Arax Advisory Partners | 3 | 14,878 | +14,875 | 0.00 | 0.00 | +0.00 | buy |
| LAZARD ASSET MANAGEMENT LLC | 14,156 | 14,156 | 0 | 0.00 | 0.00 | -0.00 | hold |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 37,081 | 13,519 | -23,562 | 0.00 | 0.00 | -0.00 | sell |
| Ground Swell Capital, LLC | 0 | 12,371 | +12,371 | 0.00 | 0.02 | +0.02 | buy |
| TWO SIGMA SECURITIES, LLC | 0 | 11,972 | +11,972 | 0.00 | 0.00 | +0.00 | buy |
| Merit Financial Group, LLC | 0 | 11,961 | +11,961 | 0.00 | 0.00 | +0.00 | buy |
| CAPTRUST FINANCIAL ADVISORS | 0 | 11,548 | +11,548 | 0.00 | 0.00 | +0.00 | buy |
| TUDOR INVESTMENT CORP ET AL | 11,028 | 11,028 | 0 | 0.00 | 0.00 | -0.00 | hold |
| SILVERCREST ASSET MANAGEMENT GROUP LLC | 0 | 10,000 | +10,000 | 0.00 | 0.00 | +0.00 | buy |
| Integrated Wealth Concepts LLC | 0 | 3,758 | +3,758 | 0.00 | 0.00 | +0.00 | buy |
| Tower Research Capital LLC (TRC) | 11,402 | 2,352 | -9,050 | 0.00 | 0.00 | -0.00 | sell |
| Optiver Holding B.V. | 3,366 | 2,269 | -1,097 | 0.00 | 0.00 | -0.00 | sell |
| FEDERATED HERMES, INC. | 1,629 | 2,097 | +468 | 0.00 | 0.00 | +0.00 | buy |
| GAMMA Investing LLC | 2,803 | 2,063 | -740 | 0.00 | 0.00 | -0.00 | sell |
| Allworth Financial LP | 491 | 1,627 | +1,136 | 0.00 | 0.00 | +0.00 | buy |
| EverSource Wealth Advisors, LLC | 4,825 | 1,491 | -3,334 | 0.00 | 0.00 | -0.00 | sell |
| BNP PARIBAS FINANCIAL MARKETS | 8,085 | 1,183 | -6,902 | 0.00 | 0.00 | -0.00 | sell |
| AdvisorNet Financial, Inc | 1,000 | 1,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Physician Wealth Advisors, Inc. | 855 | 855 | 0 | 0.00 | 0.00 | -0.00 | hold |
| True Wealth Design, LLC | 165 | 441 | +276 | 0.00 | 0.00 | +0.00 | buy |
| ROTHSCHILD INVESTMENT LLC | 143 | 341 | +198 | 0.00 | 0.00 | +0.00 | buy |
| Parallel Advisors, LLC | 336 | 336 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Steward Partners Investment Advisory, LLC | 101 | 102 | +1 | 0.00 | 0.00 | +0.00 | buy |
| Fortitude Family Office, LLC | 0 | 90 | +90 | 0.00 | 0.00 | +0.00 | buy |
| SJS Investment Consulting Inc. | 9 | 83 | +74 | 0.00 | 0.00 | +0.00 | buy |
| IFP Advisors, Inc | 158 | 76 | -82 | 0.00 | 0.00 | -0.00 | sell |
| Transamerica Financial Advisors, LLC | 56 | 45 | -11 | 0.00 | 0.00 | -0.00 | sell |
| Caitong International Asset Management Co., Ltd | 7 | 40 | +33 | 0.00 | 0.00 | +0.00 | buy |
| Clearstead Advisors, LLC | 0 | 39 | +39 | 0.00 | 0.00 | +0.00 | buy |
| SBI Securities Co., Ltd. | 15 | 15 | 0 | 0.00 | 0.00 | -0.00 | hold |
| FIFTH THIRD BANCORP | 12 | 12 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Atlantic Union Bankshares Corp | 10 | 10 | 0 | 0.00 | 0.00 | -0.00 | hold |
| JPL Wealth Management, LLC | 0 | 9 | +9 | 0.00 | 0.00 | +0.00 | buy |
| MAI Capital Management | 69 | 0 | -69 | 0.00 | 0.00 | -0.00 | sell |
| Ameritas Investment Partners, Inc. | 3,617 | 0 | -3,617 | 0.00 | 0.00 | -0.00 | sell |
| INTECH INVESTMENT MANAGEMENT LLC | 10,105 | 0 | -10,105 | 0.00 | 0.00 | -0.00 | sell |
| ALLIANCEBERNSTEIN L.P. | 52,200 | 0 | -52,200 | 0.00 | 0.00 | -0.00 | sell |
| Sterling Capital Management LLC | 248 | 0 | -248 | 0.00 | 0.00 | -0.00 | sell |
| Bank of New York Mellon Corp | 92,720 | 0 | -92,720 | 0.00 | 0.00 | -0.00 | sell |
| SIMPLEX TRADING, LLC | 4,064 | 0 | -4,064 | 0.00 | 0.00 | -0.00 | sell |
| NINE MASTS CAPITAL Ltd | 38,598 | 0 | -38,598 | 0.01 | 0.00 | -0.01 | sell |
| Russell Investments Group, Ltd. | 3,892 | 0 | -3,892 | 0.00 | 0.00 | -0.00 | sell |