| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 330,000 | 730,000 | +400,000 | 0.00 | 0.00 | +0.00 | buy |
| Ikarian Capital, LLC | 28,493 | 678,142 | +649,649 | 0.01 | 0.10 | +0.09 | buy |
| ORBIMED ADVISORS LLC | 605,531 | 605,531 | 0 | 0.03 | 0.01 | -0.01 | hold |
| BOOTHBAY FUND MANAGEMENT, LLC | 0 | 194,536 | +194,536 | 0.00 | 0.01 | +0.01 | buy |
| ADAR1 Capital Management, LLC | 0 | 154,431 | +154,431 | 0.00 | 0.01 | +0.01 | buy |
| VANGUARD GROUP INC | 87,259 | 87,259 | 0 | 0.00 | 0.00 | -0.00 | hold |
| GEODE CAPITAL MANAGEMENT, LLC | 43,440 | 61,653 | +18,213 | 0.00 | 0.00 | -0.00 | buy |
| XTX Topco Ltd | 10,708 | 42,210 | +31,502 | 0.00 | 0.00 | +0.00 | buy |
| STATE STREET CORP | 0 | 25,802 | +25,802 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA INVESTMENTS, LP | 22,018 | 19,244 | -2,774 | 0.00 | 0.00 | -0.00 | sell |
| SBI Securities Co., Ltd. | 162 | 162 | 0 | 0.00 | 0.00 | -0.00 | hold |
| ASSETMARK, INC | 2 | 0 | -2 | 0.00 | 0.00 | -0.00 | sell |
| HRT FINANCIAL LP | 12,573 | 0 | -12,573 | 0.00 | 0.00 | -0.00 | sell |
| Vermillion & White Wealth Management Group, LLC | 96 | 0 | -96 | 0.00 | 0.00 | -0.00 | sell |
| Vestal Point Capital, LP | 150,000 | 0 | -150,000 | 0.01 | 0.00 | -0.01 | sell |
| CITIGROUP INC | 3,528 | 0 | -3,528 | 0.00 | 0.00 | -0.00 | sell |