| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| STATE STREET CORP | 2,181,901 | 3,397,150 | +1,215,249 | 0.00 | 0.00 | +0.00 | buy |
| Boxer Capital Management, LLC | 590,000 | 1,395,156 | +805,156 | 2.35 | 2.53 | +0.18 | buy |
| Soleus Capital Management, L.P. | 0 | 761,737 | +761,737 | 0.00 | 0.63 | +0.63 | buy |
| BlackRock, Inc. | 3,421,815 | 4,145,061 | +723,246 | 0.00 | 0.00 | -0.00 | buy |
| TANG CAPITAL MANAGEMENT LLC | 3,399,900 | 4,099,900 | +700,000 | 5.25 | 4.48 | -0.77 | buy |
| GOLDMAN SACHS GROUP INC | 911,976 | 1,578,131 | +666,155 | 0.00 | 0.00 | +0.00 | buy |
| MERCER GLOBAL ADVISORS INC /ADV | 402,999 | 802,732 | +399,733 | 0.02 | 0.02 | +0.01 | buy |
| FMR LLC | 772,649 | 1,137,730 | +365,081 | 0.00 | 0.00 | -0.00 | buy |
| CITADEL ADVISORS LLC | 539,232 | 814,444 | +275,212 | 0.01 | 0.01 | -0.00 | buy |
| SUVRETTA CAPITAL MANAGEMENT, LLC | 3,818,600 | 4,092,784 | +274,184 | 3.15 | 2.07 | -1.08 | buy |
| MORGAN STANLEY | 423,819 | 684,515 | +260,696 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 1,118,326 | 1,372,286 | +253,960 | 0.00 | 0.00 | -0.00 | buy |
| UBS Group AG | 371,984 | 619,661 | +247,677 | 0.00 | 0.00 | +0.00 | buy |
| DG Capital Management, LLC | 392,096 | 611,595 | +219,499 | 5.15 | 5.10 | -0.05 | buy |
| BALYASNY ASSET MANAGEMENT L.P. | 297,123 | 486,836 | +189,713 | 0.02 | 0.02 | +0.00 | buy |
| Sixth Street Partners Management Company, L.P. | 0 | 160,938 | +160,938 | 0.00 | 0.00 | +0.00 | buy |
| GROUP ONE TRADING LLC | 127,138 | 272,609 | +145,471 | 0.13 | 0.19 | +0.06 | buy |
| D. E. Shaw & Co., Inc. | 0 | 123,746 | +123,746 | 0.00 | 0.00 | +0.00 | buy |
| NORTHERN TRUST CORP | 417,543 | 503,532 | +85,989 | 0.00 | 0.00 | -0.00 | buy |
| Ikarian Capital, LLC | 528,015 | 604,215 | +76,200 | 2.30 | 2.38 | +0.09 | buy |
| Rock Springs Capital Management LP | 0 | 74,448 | +74,448 | 0.00 | 0.09 | +0.09 | buy |
| Longaeva Partners L.P. | 0 | 74,046 | +74,046 | 0.00 | 0.05 | +0.05 | buy |
| Nuveen, LLC | 162,906 | 236,612 | +73,706 | 0.00 | 0.00 | +0.00 | buy |
| Caption Management, LLC | 0 | 72,000 | +72,000 | 0.00 | 0.06 | +0.06 | buy |
| CITIGROUP INC | 11,036 | 80,123 | +69,087 | 0.00 | 0.00 | +0.00 | buy |
| Pier Capital, LLC | 44,401 | 111,908 | +67,507 | 0.22 | 0.36 | +0.13 | buy |
| Curated Wealth Partners LLC | 0 | 50,000 | +50,000 | 0.00 | 0.00 | +0.00 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 126,023 | 160,938 | +34,915 | 0.00 | 0.00 | -0.00 | buy |
| WELLS FARGO & COMPANY/MN | 21,424 | 53,188 | +31,764 | 0.00 | 0.00 | +0.00 | buy |
| Bank of New York Mellon Corp | 130,730 | 161,767 | +31,037 | 0.00 | 0.00 | -0.00 | buy |
| ALGERT GLOBAL LLC | 0 | 30,610 | +30,610 | 0.00 | 0.01 | +0.01 | buy |
| TWINBEECH CAPITAL LP | 0 | 28,337 | +28,337 | 0.00 | 0.12 | +0.12 | buy |
| Anson Funds Management LP | 0 | 25,000 | +25,000 | 0.00 | 0.05 | +0.05 | buy |
| Jump Financial, LLC | 0 | 23,036 | +23,036 | 0.00 | 0.00 | +0.00 | buy |
| FOX RUN MANAGEMENT, L.L.C. | 0 | 22,666 | +22,666 | 0.00 | 0.09 | +0.09 | buy |
| XTX Topco Ltd | 0 | 21,993 | +21,993 | 0.00 | 0.01 | +0.01 | buy |
| FRANKLIN RESOURCES INC | 24,073 | 43,568 | +19,495 | 0.00 | 0.00 | +0.00 | buy |
| DEUTSCHE BANK AG\ | 38,585 | 57,579 | +18,994 | 0.00 | 0.00 | +0.00 | buy |
| JPMORGAN CHASE & CO | 343,613 | 362,501 | +18,888 | 0.00 | 0.00 | -0.00 | buy |
| HBK Sorce Advisory LLC | 204,837 | 223,076 | +18,239 | 0.13 | 0.02 | -0.11 | buy |
| ALLIANCEBERNSTEIN L.P. | 40,430 | 57,300 | +16,870 | 0.00 | 0.00 | +0.00 | buy |
| BOOTHBAY FUND MANAGEMENT, LLC | 176,145 | 192,962 | +16,817 | 0.12 | 0.09 | -0.04 | buy |
| TUDOR INVESTMENT CORP ET AL | 0 | 15,816 | +15,816 | 0.00 | 0.00 | +0.00 | buy |
| RHUMBLINE ADVISERS | 52,083 | 67,881 | +15,798 | 0.00 | 0.00 | -0.00 | buy |
| Birchview Capital, LP | 0 | 14,352 | +14,352 | 0.00 | 0.16 | +0.16 | buy |
| nVerses Capital, LLC | 0 | 13,951 | +13,951 | 0.00 | 0.52 | +0.52 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 30,995 | 44,748 | +13,753 | 0.00 | 0.00 | -0.00 | buy |
| OPPENHEIMER & CO INC | 63,666 | 75,714 | +12,048 | 0.02 | 0.02 | -0.00 | buy |
| Arrowpoint Investment Partners (Singapore) Pte. Ltd. | 0 | 9,342 | +9,342 | 0.00 | 0.07 | +0.07 | buy |
| DeepCurrents Investment Group LLC | 0 | 9,045 | +9,045 | 0.00 | 0.01 | +0.01 | buy |
| MetLife Investment Management, LLC | 23,195 | 31,380 | +8,185 | 0.00 | 0.00 | -0.00 | buy |
| Russell Investments Group, Ltd. | 4,581 | 12,595 | +8,014 | 0.00 | 0.00 | +0.00 | buy |
| STATE OF WISCONSIN INVESTMENT BOARD | 59,575 | 66,888 | +7,313 | 0.00 | 0.00 | -0.00 | buy |
| Squarepoint Ops LLC | 12,500 | 19,731 | +7,231 | 0.00 | 0.00 | +0.00 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 24,841 | 31,779 | +6,938 | 0.00 | 0.00 | -0.00 | buy |
| FOUNDATIONS INVESTMENT ADVISORS, LLC | 54,004 | 60,010 | +6,006 | 0.02 | 0.01 | -0.01 | buy |
| NEW YORK STATE COMMON RETIREMENT FUND | 13,000 | 18,900 | +5,900 | 0.00 | 0.00 | +0.00 | buy |
| Police & Firemen's Retirement System of New Jersey | 11,349 | 15,862 | +4,513 | 0.00 | 0.00 | -0.00 | buy |
| SG Americas Securities, LLC | 6,333 | 10,604 | +4,271 | 0.00 | 0.00 | -0.00 | buy |
| VOYA INVESTMENT MANAGEMENT LLC | 7,420 | 10,432 | +3,012 | 0.00 | 0.00 | -0.00 | buy |
| PROFUND ADVISORS LLC | 27,958 | 30,482 | +2,524 | 0.03 | 0.02 | -0.01 | buy |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 11,684 | 14,021 | +2,337 | 0.00 | 0.00 | -0.00 | buy |
| Virtus Investment Advisers, LLC | 10,479 | 12,682 | +2,203 | 0.09 | 0.07 | -0.02 | buy |
| INTECH INVESTMENT MANAGEMENT LLC | 15,090 | 17,114 | +2,024 | 0.00 | 0.00 | -0.00 | buy |
| STIFEL FINANCIAL CORP | 10,137 | 11,956 | +1,819 | 0.00 | 0.00 | -0.00 | buy |
| Creative Planning | 16,780 | 18,587 | +1,807 | 0.00 | 0.00 | -0.00 | buy |
| Ensign Peak Advisors, Inc | 1,300 | 3,100 | +1,800 | 0.00 | 0.00 | +0.00 | buy |
| ROYAL BANK OF CANADA | 3,695 | 5,494 | +1,799 | 0.00 | 0.00 | +0.00 | buy |
| China Universal Asset Management Co., Ltd. | 0 | 1,600 | +1,600 | 0.00 | 0.00 | +0.00 | buy |
| Jefferies Financial Group Inc. | 104,361 | 105,755 | +1,394 | 0.04 | 0.02 | -0.02 | buy |
| Legal & General Group Plc | 37,138 | 38,513 | +1,375 | 0.00 | 0.00 | -0.00 | buy |
| OneDigital Investment Advisors LLC | 10,061 | 11,384 | +1,323 | 0.00 | 0.00 | -0.00 | buy |
| Ameritas Investment Partners, Inc. | 3,566 | 4,881 | +1,315 | 0.00 | 0.00 | -0.00 | buy |
| Woodline Partners LP | 137,655 | 138,773 | +1,118 | 0.02 | 0.01 | -0.01 | buy |
| Pacer Advisors, Inc. | 0 | 1,008 | +1,008 | 0.00 | 0.00 | +0.00 | buy |
| Integrated Wealth Concepts LLC | 0 | 756 | +756 | 0.00 | 0.00 | +0.00 | buy |
| SUMMIT SECURITIES GROUP LLC | 0 | 682 | +682 | 0.00 | 0.00 | +0.00 | buy |
| E Fund Management Co., Ltd. | 7,838 | 8,513 | +675 | 0.01 | 0.00 | -0.00 | buy |
| Quantbot Technologies LP | 0 | 601 | +601 | 0.00 | 0.00 | +0.00 | buy |
| RAYMOND JAMES FINANCIAL INC | 196,300 | 196,856 | +556 | 0.00 | 0.00 | -0.00 | buy |
| State of Wyoming | 799 | 1,252 | +453 | 0.00 | 0.00 | +0.00 | buy |
| Arax Advisory Partners | 0 | 409 | +409 | 0.00 | 0.00 | +0.00 | buy |
| Quantinno Capital Management LP | 14,472 | 14,841 | +369 | 0.00 | 0.00 | -0.00 | buy |
| IFP Advisors, Inc | 0 | 325 | +325 | 0.00 | 0.00 | +0.00 | buy |
| NISA INVESTMENT ADVISORS, LLC | 417 | 583 | +166 | 0.00 | 0.00 | -0.00 | buy |
| SIGNATUREFD, LLC | 0 | 101 | +101 | 0.00 | 0.00 | +0.00 | buy |
| GAMMA Investing LLC | 287 | 323 | +36 | 0.00 | 0.00 | -0.00 | buy |
| FIFTH THIRD BANCORP | 69 | 105 | +36 | 0.00 | 0.00 | +0.00 | buy |
| COMMONWEALTH EQUITY SERVICES, LLC | 26,752 | 26,775 | +23 | 0.00 | 0.00 | -0.00 | buy |
| ROTHSCHILD INVESTMENT LLC | 28 | 43 | +15 | 0.00 | 0.00 | -0.00 | buy |
| Covestor Ltd | 5 | 19 | +14 | 0.00 | 0.00 | 0.00 | buy |
| NATIONAL BANK OF CANADA /FI/ | 0 | 11 | +11 | 0.00 | 0.00 | +0.00 | buy |
| Global Retirement Partners, LLC | 0 | 5 | +5 | 0.00 | 0.00 | +0.00 | buy |
| Hughes Financial Services, LLC | 11 | 12 | +1 | 0.00 | 0.00 | -0.00 | buy |
| MONETA GROUP INVESTMENT ADVISORS LLC | 9,399 | 9,399 | 0 | 0.00 | 0.00 | -0.00 | hold |
| LOS ANGELES CAPITAL MANAGEMENT LLC | 278 | 278 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Palo Alto Investors LP | 229,763 | 229,763 | 0 | 1.07 | 0.76 | -0.30 | hold |
| RA CAPITAL MANAGEMENT, L.P. | 1,507,844 | 1,507,844 | 0 | 0.49 | 0.32 | -0.17 | hold |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 12,840 | 12,840 | 0 | 0.00 | 0.00 | -0.00 | hold |
| KBC Group NV | 1,461 | 1,461 | 0 | 0.00 | 0.00 | -0.00 | hold |