| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| BlackRock, Inc. | 6,375,943 | 6,690,192 | +314,249 | 0.02 | 0.02 | -0.01 | buy |
| STATE STREET CORP | 3,042,454 | 3,197,555 | +155,101 | 0.02 | 0.01 | -0.01 | buy |
| AQR CAPITAL MANAGEMENT LLC | 1,598,724 | 2,455,135 | +856,411 | 0.15 | 0.13 | -0.02 | buy |
| BAILLIE GIFFORD & CO | 2,029,492 | 2,042,313 | +12,821 | 0.44 | 0.28 | -0.15 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 2,025,698 | 2,003,861 | -21,837 | 0.03 | 0.02 | -0.01 | sell |
| TWO SIGMA INVESTMENTS, LP | 762,349 | 1,903,734 | +1,141,385 | 0.13 | 0.22 | +0.09 | buy |
| Invesco Ltd. | 1,096,537 | 1,694,651 | +598,114 | 0.03 | 0.02 | -0.01 | buy |
| T. Rowe Price Investment Management, Inc. | 1,815,742 | 1,512,160 | -303,582 | 0.26 | 0.15 | -0.11 | sell |
| MORGAN STANLEY | 1,145,931 | 1,479,050 | +333,119 | 0.01 | 0.01 | -0.00 | buy |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | 1,229,928 | 1,471,069 | +241,141 | 0.14 | 0.10 | -0.04 | buy |
| Clearbridge Investments, LLC | 1,321,026 | 1,319,381 | -1,645 | 0.24 | 0.17 | -0.08 | sell |
| Soleus Capital Management, L.P. | 562,500 | 1,049,000 | +486,500 | 4.78 | 5.50 | +0.72 | buy |
| NORGES BANK | 0 | 1,047,986 | +1,047,986 | 0.00 | 0.02 | +0.02 | buy |
| JUPITER ASSET MANAGEMENT LTD | 709,902 | 1,026,691 | +316,789 | 0.79 | 0.78 | -0.02 | buy |
| FMR LLC | 3,974,712 | 964,297 | -3,010,415 | 0.04 | 0.01 | -0.04 | sell |
| MILLENNIUM MANAGEMENT LLC | 298,592 | 865,387 | +566,795 | 0.05 | 0.09 | +0.04 | buy |
| FIL Ltd | 1,012,005 | 840,026 | -171,979 | 0.16 | 0.09 | -0.07 | sell |
| GOLDMAN SACHS GROUP INC | 863,916 | 818,265 | -45,651 | 0.02 | 0.01 | -0.01 | sell |
| CITADEL ADVISORS LLC | 153,439 | 796,746 | +643,307 | 0.02 | 0.07 | +0.05 | buy |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 795,347 | 773,361 | -21,986 | 0.03 | 0.02 | -0.01 | sell |
| FEDERATED HERMES, INC. | 713,892 | 702,194 | -11,698 | 0.24 | 0.15 | -0.09 | sell |
| Vestal Point Capital, LP | 50,601 | 670,000 | +619,399 | 0.30 | 2.38 | +2.09 | buy |
| Qube Research & Technologies Ltd | 641,676 | 663,968 | +22,292 | 0.19 | 0.11 | -0.08 | buy |
| NORTHERN TRUST CORP | 693,817 | 649,908 | -43,909 | 0.02 | 0.01 | -0.01 | sell |
| FRONTIER CAPITAL MANAGEMENT CO LLC | 172,513 | 622,506 | +449,993 | 0.37 | 0.88 | +0.51 | buy |
| NORDEA INVESTMENT MANAGEMENT AB | 557,290 | 618,174 | +60,884 | 0.11 | 0.08 | -0.03 | buy |
| Sixth Street Partners Management Company, L.P. | 0 | 597,871 | +597,871 | 0.00 | 0.01 | +0.01 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 543,753 | 597,871 | +54,118 | 0.02 | 0.01 | -0.01 | buy |
| JPMORGAN CHASE & CO | 287,153 | 595,123 | +307,970 | 0.00 | 0.01 | +0.00 | buy |
| DIMENSIONAL FUND ADVISORS LP | 369,197 | 547,577 | +178,380 | 0.02 | 0.02 | -0.00 | buy |
| UBS Group AG | 445,939 | 543,030 | +97,091 | 0.02 | 0.01 | -0.00 | buy |
| Man Group plc | 716,426 | 517,217 | -199,209 | 0.31 | 0.14 | -0.17 | sell |
| Amundi | 446,918 | 507,847 | +60,929 | 0.03 | 0.02 | -0.01 | buy |
| AMERIPRISE FINANCIAL INC | 304,079 | 506,374 | +202,295 | 0.01 | 0.02 | +0.00 | buy |
| Alecta Tjanstepension Omsesidigt | 394,300 | 469,400 | +75,100 | 0.40 | 0.30 | -0.10 | buy |
| ACADIAN ASSET MANAGEMENT LLC | 256,584 | 446,382 | +189,798 | 0.08 | 0.08 | +0.00 | buy |
| Vinva Investment Management Ltd | 228,837 | 430,460 | +201,623 | 0.60 | 0.46 | -0.15 | buy |
| D. E. Shaw & Co., Inc. | 133,597 | 426,520 | +292,923 | 0.02 | 0.04 | +0.02 | buy |
| BANK OF AMERICA CORP /DE/ | 396,040 | 426,409 | +30,369 | 0.01 | 0.00 | -0.00 | buy |
| Bank of New York Mellon Corp | 383,432 | 398,130 | +14,698 | 0.01 | 0.01 | -0.00 | buy |
| WESTFIELD CAPITAL MANAGEMENT CO LP | 1,682 | 352,717 | +351,035 | 0.00 | 0.18 | +0.17 | buy |
| Stephens Investment Management Group LLC | 177,707 | 337,747 | +160,040 | 0.51 | 0.55 | +0.04 | buy |
| DEUTSCHE BANK AG\ | 341,687 | 335,980 | -5,707 | 0.02 | 0.01 | -0.01 | sell |
| Quantinno Capital Management LP | 224,951 | 316,922 | +91,971 | 0.08 | 0.06 | -0.02 | buy |
| Legal & General Group Plc | 326,039 | 311,452 | -14,587 | 0.02 | 0.01 | -0.01 | sell |
| Nuveen, LLC | 298,791 | 289,821 | -8,970 | 0.02 | 0.01 | -0.01 | sell |
| Aberdeen Group plc | 244,757 | 287,840 | +43,083 | 0.08 | 0.06 | -0.02 | buy |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC | 83,763 | 273,682 | +189,919 | 0.07 | 0.18 | +0.11 | buy |
| Squarepoint Ops LLC | 21,311 | 267,642 | +246,331 | 0.01 | 0.08 | +0.07 | buy |
| WORLDQUANT MILLENNIUM ADVISORS LLC | 463,397 | 266,689 | -196,708 | 0.37 | 0.14 | -0.24 | sell |
| Allianz Asset Management GmbH | 247,097 | 264,448 | +17,351 | 0.06 | 0.04 | -0.02 | buy |
| Artisan Partners Limited Partnership | 692,974 | 260,245 | -432,729 | 0.24 | 0.06 | -0.17 | sell |
| RAYMOND JAMES FINANCIAL INC | 257,726 | 249,250 | -8,476 | 0.02 | 0.01 | -0.01 | sell |
| Chicago Capital, LLC | 202,246 | 241,803 | +39,557 | 1.14 | 0.89 | -0.26 | buy |
| ROYAL BANK OF CANADA | 299,625 | 240,879 | -58,746 | 0.01 | 0.01 | -0.01 | sell |
| BNP Paribas Asset Management Holding S.A. | 224,873 | 239,685 | +14,812 | 0.05 | 0.04 | -0.02 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 86,020 | 221,195 | +135,175 | 0.01 | 0.02 | +0.01 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 282,637 | 214,349 | -68,288 | 0.01 | 0.00 | -0.00 | sell |
| NOMURA ASSET MANAGEMENT CO LTD | 187,917 | 212,280 | +24,363 | 0.10 | 0.07 | -0.03 | buy |
| LOS ANGELES CAPITAL MANAGEMENT LLC | 185,745 | 206,017 | +20,272 | 0.15 | 0.12 | -0.04 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 426,003 | 202,083 | -223,920 | 0.14 | 0.04 | -0.10 | sell |
| Swiss National Bank | 206,500 | 195,300 | -11,200 | 0.02 | 0.02 | -0.01 | sell |
| CANADA PENSION PLAN INVESTMENT BOARD | 143,510 | 186,330 | +42,820 | 0.02 | 0.02 | -0.00 | buy |
| PARNASSUS INVESTMENTS, LLC | 169,019 | 177,819 | +8,800 | 0.10 | 0.07 | -0.03 | buy |
| Mitsubishi UFJ Asset Management Co., Ltd. | 160,116 | 173,480 | +13,364 | 0.02 | 0.01 | -0.01 | buy |
| Capital World Investors | 168,001 | 172,712 | +4,711 | 0.00 | 0.00 | -0.00 | buy |
| Robeco Institutional Asset Management B.V. | 180,695 | 172,529 | -8,166 | 0.05 | 0.03 | -0.02 | sell |
| CAISSE DE DEPOT ET PLACEMENT DU QUEBEC | 1,418 | 170,294 | +168,876 | 0.00 | 0.04 | +0.04 | buy |
| HSBC HOLDINGS PLC | 175,967 | 165,958 | -10,009 | 0.02 | 0.01 | -0.01 | sell |
| RHUMBLINE ADVISERS | 157,468 | 165,210 | +7,742 | 0.03 | 0.02 | -0.01 | buy |
| FRANKLIN RESOURCES INC | 32,477 | 164,969 | +132,492 | 0.00 | 0.01 | +0.00 | buy |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 162,723 | 160,405 | -2,318 | 0.06 | 0.04 | -0.02 | sell |
| Sumitomo Mitsui Trust Group, Inc. | 166,454 | 159,997 | -6,457 | 0.02 | 0.01 | -0.01 | sell |
| CITIGROUP INC | 66,493 | 158,903 | +92,410 | 0.01 | 0.01 | +0.00 | buy |
| Russell Investments Group, Ltd. | 132,518 | 157,139 | +24,621 | 0.03 | 0.02 | -0.01 | buy |
| Bridgewater Associates, LP | 35,336 | 156,413 | +121,077 | 0.03 | 0.10 | +0.06 | buy |
| TREMBLANT CAPITAL GROUP | 107,226 | 156,111 | +48,885 | 0.72 | 0.68 | -0.04 | buy |
| Capital Research Global Investors | 1,669,556 | 155,313 | -1,514,243 | 0.05 | 0.00 | -0.05 | sell |
| Hudson Bay Capital Management LP | 110,000 | 155,000 | +45,000 | 0.14 | 0.11 | -0.03 | buy |
| Candriam S.C.A. | 45,769 | 151,100 | +105,331 | 0.05 | 0.10 | +0.05 | buy |
| Eversept Partners, LP | 143,546 | 148,816 | +5,270 | 1.99 | 1.24 | -0.75 | buy |
| Korea Investment CORP | 40,011 | 145,651 | +105,640 | 0.02 | 0.04 | +0.02 | buy |
| ALGERT GLOBAL LLC | 82,307 | 144,584 | +62,277 | 0.26 | 0.26 | +0.00 | buy |
| CAPITAL FUND MANAGEMENT S.A. | 29,770 | 144,303 | +114,533 | 0.06 | 0.16 | +0.10 | buy |
| TUDOR INVESTMENT CORP ET AL | 0 | 140,151 | +140,151 | 0.00 | 0.09 | +0.09 | buy |
| SEI INVESTMENTS CO | 156,602 | 136,399 | -20,203 | 0.03 | 0.02 | -0.01 | sell |
| Parkman Healthcare Partners LLC | 156,561 | 131,378 | -25,183 | 3.41 | 2.05 | -1.35 | sell |
| Bellevue Group AG | 163,656 | 127,498 | -36,158 | 0.82 | 0.41 | -0.41 | sell |
| TD ASSET MANAGEMENT INC | 140,801 | 124,164 | -16,637 | 0.02 | 0.02 | -0.01 | sell |
| WELLS FARGO & COMPANY/MN | 118,631 | 121,658 | +3,027 | 0.00 | 0.00 | -0.00 | buy |
| AMERICAN CENTURY COMPANIES INC | 1,591,410 | 119,351 | -1,472,059 | 0.17 | 0.01 | -0.16 | sell |
| Baird Financial Group, Inc. | 133,415 | 117,326 | -16,089 | 0.04 | 0.02 | -0.02 | sell |
| SEGALL BRYANT & HAMILL, LLC | 83,769 | 115,497 | +31,728 | 0.18 | 0.21 | +0.03 | buy |
| BARCLAYS PLC | 128,512 | 113,472 | -15,040 | 0.01 | 0.01 | -0.00 | sell |
| Trexquant Investment LP | 102,230 | 109,474 | +7,244 | 0.16 | 0.10 | -0.05 | buy |
| DnB Asset Management AS | 69,182 | 104,825 | +35,643 | 0.05 | 0.04 | -0.01 | buy |
| SG Americas Securities, LLC | 318,848 | 101,745 | -217,103 | 0.07 | 0.01 | -0.06 | sell |
| C WorldWide Group Holding A/S | 99,908 | 99,908 | 0 | 0.45 | 0.37 | -0.08 | hold |
| PRIMECAP MANAGEMENT CO/CA/ | 100,720 | 99,310 | -1,410 | 0.02 | 0.01 | -0.01 | sell |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 104,002 | 95,647 | -8,355 | 0.02 | 0.01 | -0.01 | sell |