| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| CITADEL ADVISORS LLC | 801 | 207,339 | +206,538 | 0.00 | 0.05 | +0.05 | buy |
| VANGUARD GROUP INC | 1,690,111 | 1,877,281 | +187,170 | 0.01 | 0.01 | -0.00 | buy |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 191,609 | 376,163 | +184,554 | 0.12 | 0.19 | +0.07 | buy |
| UBS Group AG | 321,507 | 505,714 | +184,207 | 0.02 | 0.03 | +0.01 | buy |
| NORGES BANK | 93,997 | 176,467 | +82,470 | 0.00 | 0.01 | +0.00 | buy |
| Polar Capital Holdings Plc | 150,220 | 225,410 | +75,190 | 0.30 | 0.36 | +0.05 | buy |
| Invesco Ltd. | 132,934 | 200,356 | +67,422 | 0.01 | 0.01 | +0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 3,476 | 69,037 | +65,561 | 0.00 | 0.02 | +0.02 | buy |
| Artisan Partners Limited Partnership | 137,738 | 201,571 | +63,833 | 0.07 | 0.09 | +0.02 | buy |
| Tri Locum Partners LP | 37,869 | 97,765 | +59,896 | 6.44 | 8.98 | +2.54 | buy |
| MARSHALL WACE, LLP | 2,800 | 55,119 | +52,319 | 0.00 | 0.02 | +0.02 | buy |
| Logos Global Management LP | 0 | 50,000 | +50,000 | 0.00 | 2.02 | +2.02 | buy |
| Point72 Asset Management, L.P. | 65,860 | 110,877 | +45,017 | 0.06 | 0.08 | +0.02 | buy |
| FRANKLIN RESOURCES INC | 18,953 | 60,715 | +41,762 | 0.00 | 0.00 | +0.00 | buy |
| VOYA INVESTMENT MANAGEMENT LLC | 9,434 | 51,090 | +41,656 | 0.00 | 0.02 | +0.01 | buy |
| Erste Asset Management GmbH | 164,400 | 201,100 | +36,700 | 0.70 | 0.51 | -0.19 | buy |
| BANK OF AMERICA CORP /DE/ | 245,961 | 277,221 | +31,260 | 0.01 | 0.01 | -0.00 | buy |
| Candriam S.C.A. | 21,372 | 49,965 | +28,593 | 0.04 | 0.09 | +0.04 | buy |
| Bank of New York Mellon Corp | 60,789 | 88,943 | +28,154 | 0.00 | 0.01 | +0.00 | buy |
| JPMORGAN CHASE & CO | 28,014 | 55,854 | +27,840 | 0.00 | 0.00 | +0.00 | buy |
| EULAV Asset Management | 10,000 | 31,000 | +21,000 | 0.08 | 0.22 | +0.14 | buy |
| Avidity Partners Management LP | 0 | 19,000 | +19,000 | 0.00 | 1.15 | +1.15 | buy |
| NEW YORK STATE COMMON RETIREMENT FUND | 44,771 | 61,062 | +16,291 | 0.02 | 0.02 | +0.00 | buy |
| BARCLAYS PLC | 46,871 | 62,674 | +15,803 | 0.01 | 0.01 | +0.00 | buy |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 26,363 | 39,809 | +13,446 | 0.00 | 0.00 | +0.00 | buy |
| D. E. Shaw & Co., Inc. | 99,006 | 111,981 | +12,975 | 0.04 | 0.03 | -0.01 | buy |
| BRAIDWELL LP | 48,690 | 60,781 | +12,091 | 0.57 | 0.63 | +0.06 | buy |
| STEMPOINT CAPITAL LP | 40,936 | 52,694 | +11,758 | 4.33 | 5.13 | +0.80 | buy |
| AMERICAN CENTURY COMPANIES INC | 158,306 | 167,784 | +9,478 | 0.03 | 0.03 | -0.00 | buy |
| Legal & General Group Plc | 14,497 | 23,109 | +8,612 | 0.00 | 0.00 | +0.00 | buy |
| MILLENNIUM MANAGEMENT LLC | 2,507 | 10,835 | +8,328 | 0.00 | 0.00 | +0.00 | buy |
| OSAIC HOLDINGS, INC. | 735 | 8,668 | +7,933 | 0.00 | 0.00 | +0.00 | buy |
| RiverFront Investment Group, LLC | 0 | 7,784 | +7,784 | 0.00 | 0.00 | +0.00 | buy |
| PRINCIPAL FINANCIAL GROUP INC | 1,434 | 9,206 | +7,772 | 0.00 | 0.00 | +0.00 | buy |
| GROUPAMA ASSET MANAGMENT | 33,452 | 40,891 | +7,439 | 0.22 | 0.20 | -0.02 | buy |
| BALYASNY ASSET MANAGEMENT L.P. | 27,215 | 34,500 | +7,285 | 0.02 | 0.02 | +0.00 | buy |
| Magnetar Financial LLC | 0 | 6,730 | +6,730 | 0.00 | 0.01 | +0.01 | buy |
| Susquehanna Portfolio Strategies, LLC | 0 | 6,250 | +6,250 | 0.00 | 0.04 | +0.04 | buy |
| EMERALD ADVISERS, LLC | 47,909 | 53,108 | +5,199 | 0.71 | 0.59 | -0.13 | buy |
| J. Safra Sarasin Holding AG | 1,792 | 6,823 | +5,031 | 0.01 | 0.04 | +0.02 | buy |
| Sivik Global Healthcare LLC | 0 | 5,000 | +5,000 | 0.00 | 0.68 | +0.68 | buy |
| MACQUARIE GROUP LTD | 15,000 | 19,643 | +4,643 | 0.01 | 0.01 | +0.00 | buy |
| Russell Investments Group, Ltd. | 29,574 | 34,015 | +4,441 | 0.01 | 0.01 | -0.00 | buy |
| Engineers Gate Manager LP | 0 | 4,423 | +4,423 | 0.00 | 0.02 | +0.02 | buy |
| CANADA PENSION PLAN INVESTMENT BOARD | 1,100 | 5,400 | +4,300 | 0.00 | 0.00 | +0.00 | buy |
| Qube Research & Technologies Ltd | 0 | 3,844 | +3,844 | 0.00 | 0.00 | +0.00 | buy |
| Cinctive Capital Management LP | 1,091 | 4,768 | +3,677 | 0.03 | 0.08 | +0.05 | buy |
| Allworth Financial LP | 20 | 3,534 | +3,514 | 0.00 | 0.01 | +0.01 | buy |
| Graham Capital Management, L.P. | 1,068 | 4,518 | +3,450 | 0.01 | 0.04 | +0.03 | buy |
| AMERIPRISE FINANCIAL INC | 4,994 | 8,406 | +3,412 | 0.00 | 0.00 | +0.00 | buy |
| ExodusPoint Capital Management, LP | 0 | 2,878 | +2,878 | 0.00 | 0.01 | +0.01 | buy |
| SCHRODER INVESTMENT MANAGEMENT GROUP | 30,406 | 33,207 | +2,801 | 0.01 | 0.01 | -0.00 | buy |
| Squarepoint Ops LLC | 1,648 | 4,382 | +2,734 | 0.00 | 0.00 | +0.00 | buy |
| LOS ANGELES CAPITAL MANAGEMENT LLC | 2,596 | 5,149 | +2,553 | 0.00 | 0.01 | +0.00 | buy |
| Illinois Municipal Retirement Fund | 0 | 2,509 | +2,509 | 0.00 | 0.01 | +0.01 | buy |
| Strid Group, LLC | 0 | 2,500 | +2,500 | 0.00 | 0.11 | +0.11 | buy |
| Bridgefront Capital, LLC | 0 | 2,143 | +2,143 | 0.00 | 0.17 | +0.17 | buy |
| Bayforest Capital Ltd | 0 | 2,107 | +2,107 | 0.00 | 0.28 | +0.28 | buy |
| Swiss National Bank | 25,400 | 27,400 | +2,000 | 0.01 | 0.00 | -0.00 | buy |
| Knott David M Jr | 0 | 2,000 | +2,000 | 0.00 | 0.27 | +0.27 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 151,251 | 153,085 | +1,834 | 0.01 | 0.01 | -0.00 | buy |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 12,356 | 14,133 | +1,777 | 0.01 | 0.00 | -0.00 | buy |
| R Squared Ltd | 0 | 1,770 | +1,770 | 0.00 | 0.30 | +0.30 | buy |
| EMERALD MUTUAL FUND ADVISERS TRUST | 35,238 | 36,920 | +1,682 | 0.83 | 0.68 | -0.15 | buy |
| Hennion & Walsh Asset Management, Inc. | 11,009 | 12,675 | +1,666 | 0.16 | 0.15 | -0.01 | buy |
| SEI INVESTMENTS CO | 15,995 | 17,542 | +1,547 | 0.01 | 0.01 | -0.00 | buy |
| Qsemble Capital Management, LP | 0 | 1,513 | +1,513 | 0.00 | 0.04 | +0.04 | buy |
| BAKER BROS. ADVISORS LP | 1,974,590 | 1,976,018 | +1,428 | 7.24 | 5.80 | -1.44 | buy |
| Y-Intercept (Hong Kong) Ltd | 0 | 1,415 | +1,415 | 0.00 | 0.01 | +0.01 | buy |
| Bayesian Capital Management, LP | 0 | 1,380 | +1,380 | 0.00 | 0.07 | +0.07 | buy |
| Man Group plc | 0 | 1,367 | +1,367 | 0.00 | 0.00 | +0.00 | buy |
| 683 Capital Management, LLC | 23,576 | 24,865 | +1,289 | 0.79 | 0.76 | -0.03 | buy |
| Pictet Asset Management Holding SA | 207,043 | 208,266 | +1,223 | 0.08 | 0.06 | -0.01 | buy |
| Brevan Howard Capital Management LP | 0 | 1,166 | +1,166 | 0.00 | 0.00 | +0.00 | buy |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 1,969 | 3,131 | +1,162 | 0.00 | 0.00 | +0.00 | buy |
| Marex Group plc | 724 | 1,811 | +1,087 | 0.00 | 0.01 | +0.01 | buy |
| MUTUAL OF AMERICA CAPITAL MANAGEMENT LLC | 11,263 | 12,309 | +1,046 | 0.04 | 0.04 | -0.00 | buy |
| RAYMOND JAMES FINANCIAL INC | 53,916 | 54,933 | +1,017 | 0.01 | 0.01 | -0.00 | buy |
| HSBC HOLDINGS PLC | 0 | 1,014 | +1,014 | 0.00 | 0.00 | +0.00 | buy |
| TD ASSET MANAGEMENT INC | 22,240 | 23,240 | +1,000 | 0.01 | 0.01 | -0.00 | buy |
| State of New Jersey Common Pension Fund D | 6,005 | 6,890 | +885 | 0.01 | 0.01 | -0.00 | buy |
| Entropy Technologies, LP | 1,102 | 1,902 | +800 | 0.04 | 0.05 | +0.01 | buy |
| ROYAL BANK OF CANADA | 8,819 | 9,603 | +784 | 0.00 | 0.00 | -0.00 | buy |
| Tower Research Capital LLC (TRC) | 1,087 | 1,851 | +764 | 0.01 | 0.02 | +0.00 | buy |
| Hood River Capital Management LLC | 243,994 | 244,738 | +744 | 1.38 | 1.03 | -0.34 | buy |
| Knights of Columbus Asset Advisors LLC | 3,867 | 4,603 | +736 | 0.09 | 0.08 | -0.00 | buy |
| Garda Capital Partners LP | 0 | 702 | +702 | 0.00 | 0.06 | +0.06 | buy |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | 0 | 701 | +701 | 0.00 | 0.00 | +0.00 | buy |
| Corton Capital Inc. | 0 | 695 | +695 | 0.00 | 0.24 | +0.24 | buy |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | 4,737 | 5,377 | +640 | 0.00 | 0.00 | -0.00 | buy |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 22,945 | 23,416 | +471 | 0.01 | 0.01 | -0.00 | buy |
| PRUDENTIAL FINANCIAL INC | 4,677 | 5,130 | +453 | 0.00 | 0.00 | -0.00 | buy |
| Arizona State Retirement System | 3,745 | 4,177 | +432 | 0.01 | 0.01 | -0.00 | buy |
| KLP KAPITALFORVALTNING AS | 2,600 | 3,000 | +400 | 0.00 | 0.00 | -0.00 | buy |
| Rockefeller Capital Management L.P. | 17,609 | 17,948 | +339 | 0.01 | 0.01 | -0.00 | buy |
| TEACHER RETIREMENT SYSTEM OF TEXAS | 3,522 | 3,860 | +338 | 0.00 | 0.00 | +0.00 | buy |
| ELEVATION POINT WEALTH PARTNERS, LLC | 0 | 311 | +311 | 0.00 | 0.01 | +0.01 | buy |
| Virtus Investment Advisers, LLC | 1,188 | 1,495 | +307 | 0.11 | 0.15 | +0.05 | buy |
| WOLVERINE TRADING, LLC | 665 | 972 | +307 | 0.01 | 0.01 | +0.00 | buy |
| Verition Fund Management LLC | 4,024 | 4,320 | +296 | 0.01 | 0.01 | -0.00 | buy |