| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Long Focus Capital Management, LLC | 0 | 6,700,000 | +6,700,000 | 0.00 | 0.49 | +0.49 | buy |
| Casdin Capital, LLC | 71,254,677 | 76,075,636 | +4,820,959 | 8.34 | 6.71 | -1.62 | buy |
| MAK CAPITAL ONE LLC | 0 | 2,774,721 | +2,774,721 | 0.00 | 0.64 | +0.64 | buy |
| Pacific Capital Partners Ltd | 1,000,000 | 1,575,000 | +575,000 | 1.03 | 1.08 | +0.05 | buy |
| ROYCE & ASSOCIATES LP | 1,455,503 | 2,000,503 | +545,000 | 0.02 | 0.02 | -0.00 | buy |
| GSA CAPITAL PARTNERS LLP | 129,734 | 608,656 | +478,922 | 0.02 | 0.06 | +0.04 | buy |
| AQR CAPITAL MANAGEMENT LLC | 50,187 | 482,912 | +432,725 | 0.00 | 0.00 | +0.00 | buy |
| EntryPoint Capital, LLC | 0 | 253,668 | +253,668 | 0.00 | 0.13 | +0.13 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 143,323 | 381,453 | +238,130 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 6,975,221 | 7,205,457 | +230,236 | 0.00 | 0.00 | -0.00 | buy |
| XTX Topco Ltd | 0 | 158,087 | +158,087 | 0.00 | 0.01 | +0.01 | buy |
| MIRABELLA FINANCIAL SERVICES LLP | 3,130,190 | 3,270,673 | +140,483 | 0.50 | 0.14 | -0.36 | buy |
| ARK Investment Management LLC | 3,323,689 | 3,452,890 | +129,201 | 0.05 | 0.04 | -0.01 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 2,332,649 | 2,443,060 | +110,411 | 0.00 | 0.00 | -0.00 | buy |
| OPPENHEIMER & CO INC | 0 | 86,600 | +86,600 | 0.00 | 0.00 | +0.00 | buy |
| Mariner, LLC | 0 | 74,145 | +74,145 | 0.00 | 0.00 | +0.00 | buy |
| STATE STREET CORP | 6,290,000 | 6,359,129 | +69,129 | 0.00 | 0.00 | -0.00 | buy |
| VANGUARD GROUP INC | 17,156,146 | 17,225,250 | +69,104 | 0.00 | 0.00 | -0.00 | buy |
| IEQ CAPITAL, LLC | 0 | 63,182 | +63,182 | 0.00 | 0.00 | +0.00 | buy |
| Impact Partnership Wealth, LLC | 0 | 53,857 | +53,857 | 0.00 | 0.01 | +0.01 | buy |
| Hollow Brook Wealth Management LLC | 5,503,381 | 5,553,381 | +50,000 | 2.96 | 1.77 | -1.19 | buy |
| RHUMBLINE ADVISERS | 370,514 | 412,761 | +42,247 | 0.00 | 0.00 | -0.00 | buy |
| Tower Research Capital LLC (TRC) | 2,129 | 40,932 | +38,803 | 0.00 | 0.00 | +0.00 | buy |
| CIBC WORLD MARKETS CORP | 27,606 | 65,454 | +37,848 | 0.00 | 0.00 | +0.00 | buy |
| TEACHER RETIREMENT SYSTEM OF TEXAS | 0 | 32,647 | +32,647 | 0.00 | 0.00 | +0.00 | buy |
| INTECH INVESTMENT MANAGEMENT LLC | 108,008 | 140,499 | +32,491 | 0.00 | 0.00 | -0.00 | buy |
| Quadrature Capital Ltd | 0 | 30,310 | +30,310 | 0.00 | 0.00 | +0.00 | buy |
| Rockefeller Capital Management L.P. | 296,631 | 324,680 | +28,049 | 0.00 | 0.00 | -0.00 | buy |
| Jump Financial, LLC | 0 | 23,700 | +23,700 | 0.00 | 0.00 | +0.00 | buy |
| Cerity Partners LLC | 0 | 22,031 | +22,031 | 0.00 | 0.00 | +0.00 | buy |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | 0 | 20,250 | +20,250 | 0.00 | 0.00 | +0.00 | buy |
| Savant Capital, LLC | 0 | 19,031 | +19,031 | 0.00 | 0.00 | +0.00 | buy |
| Dynamic Technology Lab Private Ltd | 0 | 16,761 | +16,761 | 0.00 | 0.00 | +0.00 | buy |
| GROUP ONE TRADING LLC | 10,475 | 26,244 | +15,769 | 0.00 | 0.00 | +0.00 | buy |
| CWM, LLC | 14,721 | 29,705 | +14,984 | 0.00 | 0.00 | +0.00 | buy |
| IQ EQ FUND MANAGEMENT (IRELAND) Ltd | 12,578 | 27,119 | +14,541 | 0.00 | 0.00 | +0.00 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 181,468 | 195,468 | +14,000 | 0.00 | 0.00 | -0.00 | buy |
| Pallas Capital Advisors LLC | 0 | 12,352 | +12,352 | 0.00 | 0.00 | +0.00 | buy |
| ENVESTNET ASSET MANAGEMENT INC | 0 | 10,116 | +10,116 | 0.00 | 0.00 | +0.00 | buy |
| HighTower Advisors, LLC | 92,791 | 102,791 | +10,000 | 0.00 | 0.00 | -0.00 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 168,777 | 176,271 | +7,494 | 0.00 | 0.00 | -0.00 | buy |
| Invesco Ltd. | 175,041 | 181,639 | +6,598 | 0.00 | 0.00 | -0.00 | buy |
| JPMORGAN CHASE & CO | 140,459 | 145,927 | +5,468 | 0.00 | 0.00 | -0.00 | buy |
| SIGNATUREFD, LLC | 0 | 5,170 | +5,170 | 0.00 | 0.00 | +0.00 | buy |
| UBS Group AG | 403,153 | 406,988 | +3,835 | 0.00 | 0.00 | -0.00 | buy |
| Smartleaf Asset Management LLC | 228 | 3,315 | +3,087 | 0.00 | 0.00 | +0.00 | buy |
| Banque Transatlantique SA | 0 | 3,000 | +3,000 | 0.00 | 0.00 | +0.00 | buy |
| FMR LLC | 9,482 | 12,418 | +2,936 | 0.00 | 0.00 | -0.00 | buy |
| PRINCIPAL FINANCIAL GROUP INC | 18,849 | 20,778 | +1,929 | 0.00 | 0.00 | -0.00 | buy |
| WELLS FARGO & COMPANY/MN | 181,256 | 182,895 | +1,639 | 0.00 | 0.00 | -0.00 | buy |
| EverSource Wealth Advisors, LLC | 23,811 | 25,348 | +1,537 | 0.00 | 0.00 | -0.00 | buy |
| Focus Partners Wealth | 14,055 | 15,282 | +1,227 | 0.00 | 0.00 | -0.00 | buy |
| XPONANCE, INC. | 20,275 | 21,378 | +1,103 | 0.00 | 0.00 | -0.00 | buy |
| True Wealth Design, LLC | 0 | 1,096 | +1,096 | 0.00 | 0.00 | +0.00 | buy |
| GAGNON SECURITIES LLC | 23,930 | 24,677 | +747 | 0.01 | 0.01 | -0.00 | buy |
| N.E.W. Advisory Services LLC | 0 | 530 | +530 | 0.00 | 0.00 | +0.00 | buy |
| CIBC Private Wealth Group LLC | 900 | 1,400 | +500 | 0.00 | 0.00 | +0.00 | buy |
| COMERICA BANK | 2,056 | 2,388 | +332 | 0.00 | 0.00 | -0.00 | buy |
| Parkside Financial Bank & Trust | 0 | 200 | +200 | 0.00 | 0.00 | +0.00 | buy |
| Allworth Financial LP | 700 | 814 | +114 | 0.00 | 0.00 | -0.00 | buy |
| PARADIGM CAPITAL MANAGEMENT INC/NY | 248,400 | 248,400 | 0 | 0.02 | 0.01 | -0.01 | hold |
| CANADA LIFE ASSURANCE Co | 21,480 | 21,480 | 0 | 0.00 | 0.00 | -0.00 | hold |
| WEXFORD CAPITAL LP | 83,638 | 83,638 | 0 | 0.04 | 0.02 | -0.01 | hold |
| Ameritas Investment Partners, Inc. | 29,558 | 29,558 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 213,266 | 213,266 | 0 | 0.00 | 0.00 | -0.00 | hold |
| VIKING GLOBAL INVESTORS LP | 58,651,170 | 58,651,170 | 0 | 0.33 | 0.20 | -0.13 | hold |
| ALLIANCEBERNSTEIN L.P. | 315,690 | 315,690 | 0 | 0.00 | 0.00 | -0.00 | hold |
| TANG CAPITAL MANAGEMENT LLC | 407,755 | 407,755 | 0 | 0.05 | 0.02 | -0.02 | hold |
| JANUS HENDERSON GROUP PLC | 131,610 | 131,610 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Amundi | 14,497 | 14,497 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 50,330 | 50,330 | 0 | 0.00 | 0.00 | -0.00 | hold |
| TAKEDA PHARMACEUTICAL CO LTD | 16,515 | 16,515 | 0 | 0.11 | 0.11 | +0.00 | hold |
| Evercore Wealth Management, LLC | 125,000 | 125,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Corvex Management LP | 44,400 | 44,400 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Slate Path Capital LP | 1,615,000 | 1,615,000 | 0 | 0.05 | 0.03 | -0.02 | hold |
| Swiss National Bank | 437,960 | 437,960 | 0 | 0.00 | 0.00 | -0.00 | hold |
| GM Advisory Group, LLC | 200,000 | 200,000 | 0 | 0.02 | 0.01 | -0.01 | hold |
| Tikvah Management LLC | 6,551,058 | 6,551,058 | 0 | 3.12 | 2.41 | -0.71 | hold |
| Intellectus Partners, LLC | 404,702 | 404,702 | 0 | 0.16 | 0.11 | -0.05 | hold |
| Parallel Advisors, LLC | 37 | 37 | 0 | 0.00 | 0.00 | -0.00 | hold |
| KLP KAPITALFORVALTNING AS | 40,166 | 40,166 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Evolution Wealth Advisors, LLC | 12,210 | 12,210 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Nan Fung Group Holdings Ltd | 1,883,179 | 1,883,179 | 0 | 2.82 | 1.66 | -1.16 | hold |
| Bellwether Advisors, LLC | 2,016 | 2,016 | 0 | 0.00 | 0.00 | -0.00 | hold |
| SBI Securities Co., Ltd. | 162 | 162 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Blue Trust, Inc. | 20 | 20 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Bradley & Co. Private Wealth Management, LLC | 179,364 | 179,364 | 0 | 0.20 | 0.13 | -0.06 | hold |
| Corient Private Wealth LLC | 13,000 | 13,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Pictet Asset Management Holding SA | 11,366 | 11,366 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Schoolcraft Capital LLC | 74,224 | 74,224 | 0 | 0.03 | 0.02 | -0.01 | hold |
| JOHNSON & JOHNSON | 311,967 | 311,967 | 0 | 0.14 | 0.10 | -0.04 | hold |
| Police & Firemen's Retirement System of New Jersey | 60,656 | 60,656 | 0 | 0.00 | 0.00 | -0.00 | hold |
| VSM Wealth Advisory, LLC | 5,000 | 5,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Dogwood Wealth Management LLC | 27 | 27 | 0 | 0.00 | 0.00 | -0.00 | hold |
| PUBLIC EMPLOYEES RETIREMENT ASSOCIATION OF COLORADO | 42,591 | 42,591 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | 0 | 0 | 0 | 0.00 | 0.00 | 0.00 | hold |
| Legal & General Group Plc | 246,951 | 246,951 | 0 | 0.00 | 0.00 | -0.00 | hold |
| NEW YORK STATE COMMON RETIREMENT FUND | 79,000 | 79,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 554,203 | 554,203 | 0 | 0.00 | 0.00 | -0.00 | hold |
| AMALGAMATED BANK | 10,438 | 10,438 | 0 | 0.00 | 0.00 | -0.00 | hold |