| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Casdin Capital, LLC | 77,558,856 | 88,783,856 | +11,225,000 | 8.41 | 7.06 | -1.35 | buy |
| VIKING GLOBAL INVESTORS LP | 58,651,170 | 58,651,170 | 0 | 0.20 | 0.20 | +0.00 | hold |
| BlackRock, Inc. | 24,920,918 | 25,515,933 | +595,015 | 0.00 | 0.00 | -0.00 | buy |
| MAK CAPITAL ONE LLC | 15,931,806 | 19,288,158 | +3,356,352 | 4.13 | 3.32 | -0.81 | buy |
| VANGUARD GROUP INC | 17,245,583 | 17,297,599 | +52,016 | 0.00 | 0.00 | -0.00 | buy |
| Long Focus Capital Management, LLC | 11,362,804 | 12,678,403 | +1,315,599 | 0.84 | 0.81 | -0.04 | buy |
| MORGAN STANLEY | 6,355,152 | 7,695,678 | +1,340,526 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 7,468,917 | 7,420,696 | -48,221 | 0.00 | 0.00 | -0.00 | sell |
| STATE STREET CORP | 6,402,649 | 6,482,766 | +80,117 | 0.00 | 0.00 | -0.00 | buy |
| Hollow Brook Wealth Management LLC | 5,775,739 | 5,553,381 | -222,358 | 1.78 | 1.84 | +0.06 | sell |
| Neuberger Berman Group LLC | 4,725,812 | 4,624,465 | -101,347 | 0.00 | 0.00 | -0.00 | sell |
| Sumitomo Mitsui Trust Group, Inc. | 5,391,829 | 4,335,887 | -1,055,942 | 0.00 | 0.00 | -0.00 | sell |
| Nikko Asset Management Americas, Inc. | 5,391,829 | 4,335,887 | -1,055,942 | 0.07 | 0.06 | -0.00 | sell |
| Tikvah Management LLC | 3,551,152 | 3,551,152 | 0 | 1.36 | 1.21 | -0.15 | hold |
| MILLENNIUM MANAGEMENT LLC | 1,453,575 | 3,387,428 | +1,933,853 | 0.00 | 0.00 | +0.00 | buy |
| BARCLAYS PLC | 3,174,634 | 3,080,579 | -94,055 | 0.00 | 0.00 | +0.00 | sell |
| ARK Investment Management LLC | 3,021,728 | 3,066,665 | +44,937 | 0.02 | 0.03 | +0.00 | buy |
| ROYCE & ASSOCIATES LP | 2,804,719 | 2,885,529 | +80,810 | 0.04 | 0.04 | +0.00 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 2,504,180 | 2,508,064 | +3,884 | 0.00 | 0.00 | -0.00 | buy |
| NORTHERN TRUST CORP | 2,593,910 | 2,390,544 | -203,366 | 0.00 | 0.00 | -0.00 | sell |
| Nan Fung Group Holdings Ltd | 1,883,179 | 1,883,179 | 0 | 4.11 | 2.16 | -1.95 | hold |
| Slate Path Capital LP | 1,615,000 | 1,615,000 | 0 | 0.03 | 0.03 | -0.00 | hold |
| CITADEL ADVISORS LLC | 488,443 | 1,076,361 | +587,918 | 0.00 | 0.00 | +0.00 | buy |
| Bank of New York Mellon Corp | 798,138 | 793,599 | -4,539 | 0.00 | 0.00 | -0.00 | sell |
| JANE STREET GROUP, LLC | 393,019 | 769,231 | +376,212 | 0.00 | 0.00 | +0.00 | buy |
| BANK OF AMERICA CORP /DE/ | 0 | 711,057 | +711,057 | 0.00 | 0.00 | +0.00 | buy |
| Nuveen, LLC | 657,212 | 657,212 | 0 | 0.00 | 0.00 | -0.00 | hold |
| LANDSCAPE CAPITAL MANAGEMENT, L.L.C. | 0 | 619,129 | +619,129 | 0.00 | 0.05 | +0.05 | buy |
| GOLDMAN SACHS GROUP INC | 1,295,966 | 526,055 | -769,911 | 0.00 | 0.00 | -0.00 | sell |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 512,708 | 519,783 | +7,075 | 0.00 | 0.00 | -0.00 | buy |
| Swiss National Bank | 470,660 | 489,660 | +19,000 | 0.00 | 0.00 | +0.00 | buy |
| Pacific Capital Partners Ltd | 1,325,000 | 475,000 | -850,000 | 1.92 | 0.65 | -1.27 | sell |
| Rockefeller Capital Management L.P. | 331,224 | 444,144 | +112,920 | 0.00 | 0.00 | +0.00 | buy |
| AQR CAPITAL MANAGEMENT LLC | 488,099 | 419,553 | -68,546 | 0.00 | 0.00 | -0.00 | sell |
| Intellectus Partners, LLC | 404,702 | 404,702 | 0 | 0.10 | 0.10 | -0.00 | hold |
| RHUMBLINE ADVISERS | 420,614 | 374,479 | -46,135 | 0.00 | 0.00 | -0.00 | sell |
| WELLS FARGO & COMPANY/MN | 242,962 | 347,720 | +104,758 | 0.00 | 0.00 | +0.00 | buy |
| ALLIANCEBERNSTEIN L.P. | 315,690 | 315,690 | 0 | 0.00 | 0.00 | -0.00 | hold |
| JOHNSON & JOHNSON | 311,967 | 311,967 | 0 | 0.08 | 0.07 | -0.01 | hold |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 140,608 | 308,783 | +168,175 | 0.00 | 0.00 | +0.00 | buy |
| Legal & General Group Plc | 291,916 | 291,916 | 0 | 0.00 | 0.00 | -0.00 | hold |
| DEUTSCHE BANK AG\ | 245,027 | 255,851 | +10,824 | 0.00 | 0.00 | -0.00 | buy |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 210,540 | 254,465 | +43,925 | 0.00 | 0.00 | +0.00 | buy |
| QVIDTVM Management LLC | 0 | 229,338 | +229,338 | 0.00 | 0.33 | +0.33 | buy |
| Qube Research & Technologies Ltd | 282,843 | 217,149 | -65,694 | 0.00 | 0.00 | -0.00 | sell |
| NEEDHAM INVESTMENT MANAGEMENT LLC | 434,435 | 209,435 | -225,000 | 0.04 | 0.02 | -0.02 | sell |
| XTX Topco Ltd | 12,994 | 206,903 | +193,909 | 0.00 | 0.01 | +0.01 | buy |
| Impact Partnership Wealth, LLC | 110,411 | 192,830 | +82,419 | 0.02 | 0.03 | +0.01 | buy |
| Invesco Ltd. | 188,153 | 186,768 | -1,385 | 0.00 | 0.00 | -0.00 | sell |
| PRICE T ROWE ASSOCIATES INC /MD/ | 157,542 | 172,134 | +14,592 | 0.00 | 0.00 | +0.00 | buy |
| PRIMECAP MANAGEMENT CO/CA/ | 176,174 | 153,374 | -22,800 | 0.00 | 0.00 | -0.00 | sell |
| STATE OF WISCONSIN INVESTMENT BOARD | 22,379 | 149,395 | +127,016 | 0.00 | 0.00 | +0.00 | buy |
| Point72 Asset Management, L.P. | 0 | 143,307 | +143,307 | 0.00 | 0.00 | +0.00 | buy |
| JANUS HENDERSON GROUP PLC | 131,610 | 131,610 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Front Street Capital Management, Inc. | 153,231 | 128,525 | -24,706 | 0.03 | 0.02 | -0.01 | sell |
| JPMORGAN CHASE & CO | 125,350 | 126,686 | +1,336 | 0.00 | 0.00 | +0.00 | buy |
| Evercore Wealth Management, LLC | 125,000 | 125,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| MetLife Investment Management, LLC | 152,929 | 124,888 | -28,041 | 0.00 | 0.00 | -0.00 | sell |
| INTECH INVESTMENT MANAGEMENT LLC | 136,141 | 121,764 | -14,377 | 0.00 | 0.00 | -0.00 | sell |
| OPPENHEIMER & CO INC | 86,600 | 119,750 | +33,150 | 0.00 | 0.00 | +0.00 | buy |
| IQ EQ FUND MANAGEMENT (IRELAND) Ltd | 73,347 | 108,416 | +35,069 | 0.01 | 0.01 | +0.00 | buy |
| SG Americas Securities, LLC | 33,039 | 94,131 | +61,092 | 0.00 | 0.00 | +0.00 | buy |
| HRT FINANCIAL LP | 0 | 93,782 | +93,782 | 0.00 | 0.00 | +0.00 | buy |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 106,138 | 92,886 | -13,252 | 0.00 | 0.00 | -0.00 | sell |
| Police & Firemen's Retirement System of New Jersey | 85,970 | 85,970 | 0 | 0.00 | 0.00 | +0.00 | hold |
| NEW YORK STATE COMMON RETIREMENT FUND | 79,000 | 79,000 | 0 | 0.00 | 0.00 | +0.00 | hold |
| BNP PARIBAS FINANCIAL MARKETS | 58,326 | 77,618 | +19,292 | 0.00 | 0.00 | +0.00 | buy |
| SEI INVESTMENTS CO | 73,584 | 71,195 | -2,389 | 0.00 | 0.00 | -0.00 | sell |
| Arizona State Retirement System | 73,056 | 69,409 | -3,647 | 0.00 | 0.00 | -0.00 | sell |
| Virtu Financial LLC | 58,696 | 62,129 | +3,433 | 0.00 | 0.00 | -0.00 | buy |
| VOYA INVESTMENT MANAGEMENT LLC | 58,402 | 58,402 | 0 | 0.00 | 0.00 | -0.00 | hold |
| ProShare Advisors LLC | 51,183 | 54,708 | +3,525 | 0.00 | 0.00 | -0.00 | buy |
| KLP KAPITALFORVALTNING AS | 40,166 | 53,066 | +12,900 | 0.00 | 0.00 | +0.00 | buy |
| HighTower Advisors, LLC | 52,791 | 52,791 | 0 | 0.00 | 0.00 | -0.00 | hold |
| MERCER GLOBAL ADVISORS INC /ADV | 0 | 50,987 | +50,987 | 0.00 | 0.00 | +0.00 | buy |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 50,330 | 50,330 | 0 | 0.00 | 0.00 | -0.00 | hold |
| GSA CAPITAL PARTNERS LLP | 0 | 47,266 | +47,266 | 0.00 | 0.01 | +0.01 | buy |
| Creative Planning | 62,996 | 46,035 | -16,961 | 0.00 | 0.00 | -0.00 | sell |
| Corvex Management LP | 44,400 | 44,400 | 0 | 0.00 | 0.00 | -0.00 | hold |
| PUBLIC EMPLOYEES RETIREMENT ASSOCIATION OF COLORADO | 42,591 | 42,591 | 0 | 0.00 | 0.00 | +0.00 | hold |
| VICTORY CAPITAL MANAGEMENT INC | 42,107 | 42,442 | +335 | 0.00 | 0.00 | -0.00 | buy |
| IEQ CAPITAL, LLC | 46,544 | 38,555 | -7,989 | 0.00 | 0.00 | -0.00 | sell |
| Cerity Partners LLC | 36,588 | 36,574 | -14 | 0.00 | 0.00 | -0.00 | sell |
| Ameritas Investment Partners, Inc. | 29,558 | 29,558 | 0 | 0.00 | 0.00 | -0.00 | hold |
| GROUP ONE TRADING LLC | 20,485 | 26,706 | +6,221 | 0.00 | 0.00 | +0.00 | buy |
| CIBC Asset Management Inc | 0 | 25,439 | +25,439 | 0.00 | 0.00 | +0.00 | buy |
| Russell Investments Group, Ltd. | 25,021 | 25,138 | +117 | 0.00 | 0.00 | -0.00 | buy |
| EverSource Wealth Advisors, LLC | 25,191 | 25,078 | -113 | 0.00 | 0.00 | -0.00 | sell |
| EntryPoint Capital, LLC | 0 | 24,607 | +24,607 | 0.00 | 0.01 | +0.01 | buy |
| CWM, LLC | 30,552 | 23,962 | -6,590 | 0.00 | 0.00 | -0.00 | sell |
| M&T BANK CORP | 0 | 23,908 | +23,908 | 0.00 | 0.00 | +0.00 | buy |
| XPONANCE, INC. | 23,402 | 23,597 | +195 | 0.00 | 0.00 | -0.00 | buy |
| AIGEN INVESTMENT MANAGEMENT, LP | 0 | 22,169 | +22,169 | 0.00 | 0.01 | +0.01 | buy |
| CANADA LIFE ASSURANCE Co | 108,603 | 21,480 | -87,123 | 0.00 | 0.00 | -0.00 | sell |
| CIBC WORLD MARKETS CORP | 36,882 | 19,803 | -17,079 | 0.00 | 0.00 | -0.00 | sell |
| MACKENZIE FINANCIAL CORP | 19,781 | 19,781 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Mariner, LLC | 19,670 | 19,628 | -42 | 0.00 | 0.00 | -0.00 | sell |
| PRUDENTIAL FINANCIAL INC | 39,307 | 18,776 | -20,531 | 0.00 | 0.00 | -0.00 | sell |
| Sterling Capital Management LLC | 20,654 | 17,241 | -3,413 | 0.00 | 0.00 | -0.00 | sell |
| FEDERATED HERMES, INC. | 28,545 | 17,001 | -11,544 | 0.00 | 0.00 | -0.00 | sell |