| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Capital World Investors | 12,789,236 | 14,971,343 | +2,182,107 | 0.32 | 0.59 | +0.28 | buy |
| VANGUARD GROUP INC | 11,994,261 | 12,507,778 | +513,517 | 0.04 | 0.06 | +0.02 | buy |
| FMR LLC | 9,967,996 | 12,164,038 | +2,196,042 | 0.10 | 0.19 | +0.09 | buy |
| WELLINGTON MANAGEMENT GROUP LLP | 7,209,005 | 6,210,479 | -998,526 | 0.19 | 0.27 | +0.08 | sell |
| BAILLIE GIFFORD & CO | 6,623,577 | 6,032,656 | -590,921 | 0.77 | 1.14 | +0.37 | sell |
| BNP Paribas Asset Management Holding S.A. | 4,950,000 | 4,950,000 | 0 | 0.01 | 0.01 | +0.00 | hold |
| Capital International Investors | 3,651,217 | 3,891,059 | +239,842 | 0.11 | 0.19 | +0.08 | buy |
| DODGE & COX | 3,811,480 | 3,780,185 | -31,295 | 0.33 | 0.55 | +0.22 | sell |
| NEW YORK STATE COMMON RETIREMENT FUND | 5,263,000 | 3,706,000 | -1,557,000 | 0.01 | 0.01 | -0.00 | sell |
| STATE STREET CORP | 3,191,373 | 3,534,836 | +343,463 | 0.02 | 0.04 | +0.02 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 3,685,753 | 3,488,003 | -197,750 | 0.07 | 0.10 | +0.03 | sell |
| Capital Research Global Investors | 3,144,987 | 3,255,648 | +110,661 | 0.11 | 0.17 | +0.07 | buy |
| T. Rowe Price Investment Management, Inc. | 2,872,904 | 3,153,627 | +280,723 | 0.26 | 0.48 | +0.22 | buy |
| Ghisallo Capital Management LLC | 0 | 2,500,000 | +2,500,000 | 0.00 | 0.23 | +0.23 | buy |
| NORGES BANK | 2,292,654 | 2,296,781 | +4,127 | 0.05 | 0.08 | +0.03 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 2,001,718 | 2,080,275 | +78,557 | 0.03 | 0.04 | +0.02 | buy |
| JPMORGAN CHASE & CO | 1,748,189 | 1,772,871 | +24,682 | 0.02 | 0.04 | +0.01 | buy |
| AMERICAN CENTURY COMPANIES INC | 1,373,654 | 1,354,169 | -19,485 | 0.13 | 0.20 | +0.07 | sell |
| Liberty Mutual Group Asset Management Inc. | 1,525,000 | 1,270,000 | -255,000 | 0.41 | 0.20 | -0.21 | sell |
| Bellevue Group AG | 918,284 | 919,834 | +1,550 | 2.09 | 3.63 | +1.54 | buy |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 758,650 | 835,413 | +76,763 | 0.04 | 0.06 | +0.02 | buy |
| NORTHERN TRUST CORP | 739,584 | 780,835 | +41,251 | 0.02 | 0.03 | +0.01 | buy |
| Legal & General Group Plc | 750,602 | 761,919 | +11,317 | 0.03 | 0.05 | +0.02 | buy |
| Pictet Asset Management Holding SA | 961,504 | 758,528 | -202,976 | 0.16 | 0.21 | +0.05 | sell |
| MORGAN STANLEY | 675,281 | 741,514 | +66,233 | 0.01 | 0.01 | +0.01 | buy |
| Amundi | 746,064 | 737,290 | -8,774 | 0.05 | 0.07 | +0.02 | sell |
| Orbis Allan Gray Ltd | 0 | 721,053 | +721,053 | 0.00 | 1.09 | +1.09 | buy |
| Bank of New York Mellon Corp | 798,445 | 673,702 | -124,743 | 0.02 | 0.03 | +0.01 | sell |
| BANK OF AMERICA CORP /DE/ | 484,893 | 631,112 | +146,219 | 0.01 | 0.01 | +0.01 | buy |
| Bank of New York Mellon Corp | 600,000 | 600,000 | 0 | 0.00 | 0.00 | +0.00 | hold |
| LOOMIS SAYLES & CO L P | 581,851 | 569,282 | -12,569 | 0.12 | 0.19 | +0.07 | sell |
| GOLDMAN SACHS GROUP INC | 260,019 | 514,667 | +254,648 | 0.01 | 0.02 | +0.02 | buy |
| Deep Track Capital, LP | 832,310 | 500,000 | -332,310 | 3.58 | 3.63 | +0.05 | sell |
| TD ASSET MANAGEMENT INC | 462,348 | 489,940 | +27,592 | 0.06 | 0.11 | +0.05 | buy |
| DEUTSCHE BANK AG\ | 507,077 | 489,118 | -17,959 | 0.04 | 0.05 | +0.02 | sell |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 447,560 | 470,592 | +23,032 | 0.02 | 0.02 | +0.01 | buy |
| ROYAL BANK OF CANADA | 374,424 | 411,364 | +36,940 | 0.01 | 0.02 | +0.01 | buy |
| CITIGROUP INC | 150,690 | 401,660 | +250,970 | 0.02 | 0.09 | +0.07 | buy |
| Avoro Capital Advisors LLC | 300,000 | 400,000 | +100,000 | 0.52 | 1.29 | +0.77 | buy |
| GILDER GAGNON HOWE & CO LLC | 405,173 | 398,616 | -6,557 | 0.76 | 1.21 | +0.46 | sell |
| Invesco Ltd. | 178,313 | 392,841 | +214,528 | 0.01 | 0.02 | +0.01 | buy |
| Swiss National Bank | 375,900 | 374,400 | -1,500 | 0.04 | 0.06 | +0.02 | sell |
| CITADEL ADVISORS LLC | 39,984 | 367,289 | +327,305 | 0.01 | 0.09 | +0.08 | buy |
| Candriam S.C.A. | 316,898 | 351,228 | +34,330 | 0.30 | 0.52 | +0.21 | buy |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 337,025 | 329,037 | -7,988 | 0.05 | 0.07 | +0.03 | sell |
| FRANKLIN RESOURCES INC | 237,524 | 289,326 | +51,802 | 0.01 | 0.02 | +0.01 | buy |
| Polar Capital Holdings Plc | 235,000 | 285,000 | +50,000 | 0.18 | 0.41 | +0.22 | buy |
| CANADA PENSION PLAN INVESTMENT BOARD | 273,790 | 283,933 | +10,143 | 0.04 | 0.07 | +0.02 | buy |
| ROYAL LONDON ASSET MANAGEMENT LTD | 326,869 | 282,345 | -44,524 | 0.12 | 0.18 | +0.05 | sell |
| D. E. Shaw & Co., Inc. | 103,387 | 279,398 | +176,011 | 0.02 | 0.10 | +0.08 | buy |
| Sumitomo Mitsui Trust Group, Inc. | 290,996 | 276,947 | -14,049 | 0.03 | 0.05 | +0.02 | sell |
| Corient Private Wealth LLC | 274,607 | 274,736 | +129 | 0.07 | 0.12 | +0.04 | buy |
| AQR CAPITAL MANAGEMENT LLC | 141,137 | 271,619 | +130,482 | 0.04 | 0.10 | +0.07 | buy |
| Mitsubishi UFJ Trust & Banking Corp | 311,852 | 268,440 | -43,412 | 0.11 | 0.16 | +0.05 | sell |
| DIMENSIONAL FUND ADVISORS LP | 255,179 | 266,206 | +11,027 | 0.01 | 0.02 | +0.01 | buy |
| TWO SIGMA ADVISERS, LP | 189,600 | 258,700 | +69,100 | 0.07 | 0.14 | +0.07 | buy |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 0 | 254,000 | +254,000 | 0.00 | 0.11 | +0.11 | buy |
| ORBIMED ADVISORS LLC | 0 | 250,300 | +250,300 | 0.00 | 1.21 | +1.21 | buy |
| Rock Springs Capital Management LP | 244,000 | 250,000 | +6,000 | 0.93 | 1.83 | +0.91 | buy |
| JANUS HENDERSON GROUP PLC | 178,954 | 249,440 | +70,486 | 0.01 | 0.03 | +0.02 | buy |
| FIRST TRUST ADVISORS LP | 217,373 | 240,547 | +23,174 | 0.03 | 0.06 | +0.03 | buy |
| ANTIPODES PARTNERS Ltd | 205,579 | 238,496 | +32,917 | 0.97 | 2.11 | +1.13 | buy |
| AMERIPRISE FINANCIAL INC | 194,725 | 238,320 | +43,595 | 0.01 | 0.02 | +0.01 | buy |
| Avidity Partners Management LP | 243,000 | 222,000 | -21,000 | 1.29 | 2.29 | +1.00 | sell |
| CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 214,330 | 215,567 | +1,237 | 0.02 | 0.04 | +0.02 | buy |
| CIBC Private Wealth Group LLC | 174,249 | 206,391 | +32,142 | 0.05 | 0.10 | +0.05 | buy |
| WELLS FARGO & COMPANY/MN | 206,364 | 206,148 | -216 | 0.01 | 0.01 | +0.00 | sell |
| Aberdeen Group plc | 219,275 | 199,978 | -19,297 | 0.06 | 0.09 | +0.03 | sell |
| National Pension Service | 186,183 | 196,387 | +10,204 | 0.03 | 0.05 | +0.02 | buy |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 191,418 | 193,594 | +2,176 | 0.04 | 0.06 | +0.02 | buy |
| Palo Alto Investors LP | 0 | 183,123 | +183,123 | 0.00 | 5.16 | +5.16 | buy |
| RHUMBLINE ADVISERS | 173,689 | 173,327 | -362 | 0.02 | 0.04 | +0.01 | sell |
| Caption Management, LLC | 114,122 | 170,550 | +56,428 | 1.88 | 4.39 | +2.51 | buy |
| Casdin Capital, LLC | 358,000 | 170,000 | -188,000 | 3.98 | 3.15 | -0.83 | sell |
| FRONTIER CAPITAL MANAGEMENT CO LLC | 0 | 168,442 | +168,442 | 0.00 | 0.41 | +0.41 | buy |
| UBS Group AG | 124,463 | 156,583 | +32,120 | 0.01 | 0.01 | +0.01 | buy |
| Sofinnova Investments, Inc. | 103,036 | 147,929 | +44,893 | 0.91 | 2.27 | +1.36 | buy |
| JANE STREET GROUP, LLC | 163,938 | 139,497 | -24,441 | 0.03 | 0.04 | +0.01 | sell |
| MILLENNIUM MANAGEMENT LLC | 202,278 | 138,504 | -63,774 | 0.03 | 0.03 | +0.00 | sell |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | 137,022 | 135,347 | -1,675 | 0.06 | 0.06 | +0.00 | sell |
| BARCLAYS PLC | 193,972 | 131,265 | -62,707 | 0.01 | 0.01 | +0.00 | sell |
| WORLDQUANT MILLENNIUM ADVISORS LLC | 60,073 | 129,593 | +69,520 | 0.11 | 0.29 | +0.18 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 101,446 | 126,012 | +24,566 | 0.02 | 0.03 | +0.01 | buy |
| HighTower Advisors, LLC | 126,080 | 125,041 | -1,039 | 0.03 | 0.05 | +0.02 | sell |
| Assenagon Asset Management S.A. | 60,342 | 122,796 | +62,454 | 0.02 | 0.07 | +0.05 | buy |
| DEERFIELD MANAGEMENT COMPANY, L.P. | 0 | 119,800 | +119,800 | 0.00 | 0.48 | +0.48 | buy |
| Novo Holdings A/S | 118,383 | 118,383 | 0 | 1.22 | 1.55 | +0.33 | hold |
| Man Group plc | 210,235 | 117,910 | -92,325 | 0.08 | 0.08 | -0.01 | sell |
| VOYA INVESTMENT MANAGEMENT LLC | 70,497 | 114,234 | +43,737 | 0.01 | 0.03 | +0.02 | buy |
| Capital International, Inc./CA/ | 93,376 | 113,984 | +20,608 | 0.19 | 0.37 | +0.18 | buy |
| DekaBank Deutsche Girozentrale | 113,042 | 113,463 | +421 | 0.03 | 0.05 | +0.02 | buy |
| Korea Investment CORP | 39,163 | 112,383 | +73,220 | 0.01 | 0.07 | +0.05 | buy |
| AXA S.A. | 107,636 | 110,975 | +3,339 | 0.05 | 0.08 | +0.03 | buy |
| Capital International Sarl | 73,109 | 109,815 | +36,706 | 0.36 | 0.81 | +0.45 | buy |
| Skandinaviska Enskilda Banken AB (publ) | 94,553 | 106,892 | +12,339 | 0.07 | 0.12 | +0.06 | buy |
| TWO SIGMA INVESTMENTS, LP | 102,512 | 102,918 | +406 | 0.04 | 0.06 | +0.02 | buy |
| SEI INVESTMENTS CO | 99,000 | 99,000 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Squarepoint Ops LLC | 580,441 | 98,794 | -481,647 | 0.36 | 0.09 | -0.27 | sell |
| Neuberger Berman Group LLC | 91,350 | 95,408 | +4,058 | 0.01 | 0.02 | +0.01 | buy |
| NEW YORK STATE COMMON RETIREMENT FUND | 93,766 | 94,685 | +919 | 0.02 | 0.03 | +0.01 | buy |