| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| BlackRock, Inc. | 9,164,538 | 9,090,029 | -74,509 | 0.02 | 0.02 | -0.00 | sell |
| JANUS HENDERSON GROUP PLC | 3,018,787 | 5,348,395 | +2,329,608 | 0.15 | 0.27 | +0.12 | buy |
| PRIMECAP MANAGEMENT CO/CA/ | 3,376,928 | 3,370,628 | -6,300 | 0.29 | 0.29 | -0.00 | sell |
| STATE STREET CORP | 2,122,402 | 2,182,617 | +60,215 | 0.01 | 0.01 | +0.00 | buy |
| AMERIPRISE FINANCIAL INC | 2,104,294 | 1,610,774 | -493,520 | 0.05 | 0.04 | -0.01 | sell |
| CITADEL ADVISORS LLC | 26,956 | 1,446,926 | +1,419,970 | 0.00 | 0.11 | +0.11 | buy |
| ALLIANCEBERNSTEIN L.P. | 1,643,448 | 1,397,556 | -245,892 | 0.06 | 0.05 | -0.01 | sell |
| Holocene Advisors, LP | 1,299,294 | 1,383,715 | +84,421 | 0.31 | 0.36 | +0.05 | buy |
| GOLDMAN SACHS GROUP INC | 1,350,425 | 1,374,958 | +24,533 | 0.02 | 0.02 | -0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 1,317,648 | 1,356,453 | +38,805 | 0.01 | 0.01 | -0.00 | buy |
| MILLENNIUM MANAGEMENT LLC | 1,609,699 | 1,173,696 | -436,003 | 0.13 | 0.09 | -0.04 | sell |
| WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC | 1,106,918 | 1,073,819 | -33,099 | 0.35 | 0.38 | +0.03 | sell |
| Capital World Investors | 850,893 | 989,060 | +138,167 | 0.01 | 0.01 | +0.00 | buy |
| Invesco Ltd. | 780,267 | 914,188 | +133,921 | 0.01 | 0.01 | +0.00 | buy |
| BRAIDWELL LP | 921,979 | 763,505 | -158,474 | 3.33 | 2.74 | -0.59 | sell |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 714,026 | 714,389 | +363 | 0.01 | 0.01 | -0.00 | buy |
| MORGAN STANLEY | 670,778 | 678,825 | +8,047 | 0.00 | 0.00 | -0.00 | buy |
| BANK OF AMERICA CORP /DE/ | 538,678 | 657,432 | +118,754 | 0.00 | 0.01 | +0.00 | buy |
| Artisan Partners Limited Partnership | 702,818 | 607,462 | -95,356 | 0.12 | 0.11 | -0.01 | sell |
| NORTHERN TRUST CORP | 587,130 | 576,209 | -10,921 | 0.01 | 0.01 | -0.00 | sell |
| DRIEHAUS CAPITAL MANAGEMENT LLC | 0 | 487,912 | +487,912 | 0.00 | 0.39 | +0.39 | buy |
| JENNISON ASSOCIATES LLC | 0 | 487,020 | +487,020 | 0.00 | 0.04 | +0.04 | buy |
| WESTFIELD CAPITAL MANAGEMENT CO LP | 0 | 482,219 | +482,219 | 0.00 | 0.22 | +0.22 | buy |
| RIVERBRIDGE PARTNERS LLC | 535,169 | 433,228 | -101,941 | 1.13 | 1.14 | +0.01 | sell |
| LOOMIS SAYLES & CO L P | 447,805 | 421,240 | -26,565 | 0.06 | 0.06 | +0.00 | sell |
| Nuveen, LLC | 406,046 | 398,329 | -7,717 | 0.01 | 0.01 | -0.00 | sell |
| Allspring Global Investments Holdings, LLC | 355,279 | 393,831 | +38,552 | 0.06 | 0.07 | +0.01 | buy |
| UBS Group AG | 873,942 | 386,400 | -487,542 | 0.02 | 0.01 | -0.01 | sell |
| Capital International Investors | 511,510 | 373,343 | -138,167 | 0.01 | 0.01 | +0.00 | sell |
| Bank of New York Mellon Corp | 355,840 | 343,173 | -12,667 | 0.01 | 0.01 | -0.00 | sell |
| PRICE T ROWE ASSOCIATES INC /MD/ | 122,169 | 336,425 | +214,256 | 0.00 | 0.00 | +0.00 | buy |
| JPMORGAN CHASE & CO | 556,479 | 323,819 | -232,660 | 0.00 | 0.00 | -0.00 | sell |
| Champlain Investment Partners, LLC | 333,264 | 319,027 | -14,237 | 0.38 | 0.44 | +0.05 | sell |
| FMR LLC | 10,083 | 303,266 | +293,183 | 0.00 | 0.00 | +0.00 | buy |
| Clearbridge Investments, LLC | 112,022 | 286,051 | +174,029 | 0.01 | 0.03 | +0.02 | buy |
| PRINCIPAL FINANCIAL GROUP INC | 274,565 | 280,737 | +6,172 | 0.02 | 0.02 | +0.00 | buy |
| D. E. Shaw & Co., Inc. | 558,290 | 251,176 | -307,114 | 0.05 | 0.02 | -0.03 | sell |
| BROWN CAPITAL MANAGEMENT LLC | 326,579 | 230,028 | -96,551 | 3.02 | 3.52 | +0.49 | sell |
| PFM Health Sciences, LP | 201,676 | 215,685 | +14,009 | 2.31 | 2.44 | +0.14 | buy |
| C WorldWide Group Holding A/S | 207,212 | 207,212 | 0 | 0.41 | 0.48 | +0.07 | hold |
| PUBLIC SECTOR PENSION INVESTMENT BOARD | 198,817 | 205,484 | +6,667 | 0.08 | 0.07 | -0.01 | buy |
| ROYAL BANK OF CANADA | 191,900 | 204,153 | +12,253 | 0.00 | 0.00 | +0.00 | buy |
| DIMENSIONAL FUND ADVISORS LP | 205,461 | 199,084 | -6,377 | 0.00 | 0.00 | -0.00 | sell |
| ExodusPoint Capital Management, LP | 0 | 179,728 | +179,728 | 0.00 | 0.19 | +0.19 | buy |
| Integral Health Asset Management, LLC | 325,000 | 175,000 | -150,000 | 1.86 | 1.00 | -0.86 | sell |
| SEI INVESTMENTS CO | 181,853 | 161,680 | -20,173 | 0.02 | 0.02 | -0.00 | sell |
| Legal & General Group Plc | 179,698 | 160,542 | -19,156 | 0.00 | 0.00 | -0.00 | sell |
| RHUMBLINE ADVISERS | 151,467 | 154,176 | +2,709 | 0.01 | 0.01 | +0.00 | buy |
| GILDER GAGNON HOWE & CO LLC | 154,442 | 152,897 | -1,545 | 0.18 | 0.20 | +0.01 | sell |
| EVENTIDE ASSET MANAGEMENT, LLC | 289,275 | 150,036 | -139,239 | 0.51 | 0.27 | -0.24 | sell |
| WELLINGTON MANAGEMENT GROUP LLP | 486,824 | 149,150 | -337,674 | 0.01 | 0.00 | -0.01 | sell |
| Neuberger Berman Group LLC | 53,778 | 147,894 | +94,116 | 0.00 | 0.01 | +0.01 | buy |
| Bellevue Group AG | 261,935 | 145,703 | -116,232 | 0.56 | 0.37 | -0.19 | sell |
| KEYBANK NATIONAL ASSOCIATION/OH | 142,506 | 145,270 | +2,764 | 0.06 | 0.06 | -0.00 | buy |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 143,192 | 143,774 | +582 | 0.00 | 0.00 | -0.00 | buy |
| AustralianSuper Pty Ltd | 449,846 | 131,535 | -318,311 | 0.24 | 0.07 | -0.16 | sell |
| SILVERCREST ASSET MANAGEMENT GROUP LLC | 104,279 | 128,294 | +24,015 | 0.08 | 0.10 | +0.02 | buy |
| SEGALL BRYANT & HAMILL, LLC | 131,404 | 124,951 | -6,453 | 0.20 | 0.14 | -0.06 | sell |
| LORD, ABBETT & CO. LLC | 0 | 120,214 | +120,214 | 0.00 | 0.04 | +0.04 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 0 | 118,892 | +118,892 | 0.00 | 0.02 | +0.02 | buy |
| FRED ALGER MANAGEMENT, LLC | 325,540 | 113,943 | -211,597 | 0.14 | 0.05 | -0.09 | sell |
| Swiss National Bank | 113,100 | 113,600 | +500 | 0.01 | 0.01 | -0.00 | buy |
| Granite Investment Partners, LLC | 119,343 | 111,872 | -7,471 | 0.80 | 0.74 | -0.06 | sell |
| Qube Research & Technologies Ltd | 188,735 | 108,863 | -79,872 | 0.03 | 0.02 | -0.01 | sell |
| Squarepoint Ops LLC | 0 | 108,049 | +108,049 | 0.00 | 0.03 | +0.03 | buy |
| Point72 Asset Management, L.P. | 161,596 | 101,340 | -60,256 | 0.03 | 0.02 | -0.01 | sell |
| RAYMOND JAMES FINANCIAL INC | 98,768 | 98,226 | -542 | 0.00 | 0.00 | -0.00 | sell |
| OSTERWEIS CAPITAL MANAGEMENT INC | 101,613 | 94,863 | -6,750 | 0.49 | 0.53 | +0.04 | sell |
| BNP Paribas Asset Management Holding S.A. | 893 | 94,538 | +93,645 | 0.00 | 0.01 | +0.01 | buy |
| WCM INVESTMENT MANAGEMENT, LLC | 97,367 | 93,427 | -3,940 | 0.02 | 0.02 | -0.00 | sell |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 42,996 | 87,752 | +44,756 | 0.01 | 0.02 | +0.01 | buy |
| Rhenman & Partners Asset Management AB | 210,000 | 84,000 | -126,000 | 2.22 | 1.12 | -1.10 | sell |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 250,000 | 81,878 | -168,122 | 0.04 | 0.01 | -0.03 | sell |
| ASSETMARK, INC | 69 | 76,306 | +76,237 | 0.00 | 0.02 | +0.02 | buy |
| NEW YORK STATE COMMON RETIREMENT FUND | 79,610 | 76,257 | -3,353 | 0.01 | 0.01 | -0.00 | sell |
| VICTORY CAPITAL MANAGEMENT INC | 80,102 | 75,985 | -4,117 | 0.01 | 0.01 | +0.00 | sell |
| CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 72,340 | 68,654 | -3,686 | 0.00 | 0.00 | -0.00 | sell |
| SIT INVESTMENT ASSOCIATES INC | 66,970 | 68,505 | +1,535 | 0.15 | 0.15 | +0.00 | buy |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 54,563 | 66,434 | +11,871 | 0.01 | 0.01 | +0.00 | buy |
| TWO SIGMA INVESTMENTS, LP | 98,651 | 63,430 | -35,221 | 0.02 | 0.01 | -0.01 | sell |
| Trexquant Investment LP | 0 | 62,381 | +62,381 | 0.00 | 0.05 | +0.05 | buy |
| CITIGROUP INC | 44,623 | 61,503 | +16,880 | 0.00 | 0.00 | +0.00 | buy |
| Eversept Partners, LP | 147,471 | 60,214 | -87,257 | 0.93 | 0.43 | -0.51 | sell |
| PRUDENTIAL FINANCIAL INC | 53,557 | 58,557 | +5,000 | 0.01 | 0.01 | +0.00 | buy |
| Corient Private Wealth LLC | 30,978 | 56,940 | +25,962 | 0.00 | 0.01 | +0.00 | buy |
| Allianz Asset Management GmbH | 55,996 | 54,853 | -1,143 | 0.01 | 0.01 | -0.00 | sell |
| ALGERT GLOBAL LLC | 155,546 | 54,201 | -101,345 | 0.27 | 0.09 | -0.19 | sell |
| Baird Financial Group, Inc. | 55,434 | 52,801 | -2,633 | 0.01 | 0.01 | -0.00 | sell |
| DEUTSCHE BANK AG\ | 46,731 | 52,096 | +5,365 | 0.00 | 0.00 | +0.00 | buy |
| ENVESTNET ASSET MANAGEMENT INC | 51,833 | 50,237 | -1,596 | 0.00 | 0.00 | -0.00 | sell |
| CANADA LIFE ASSURANCE Co | 50,101 | 47,913 | -2,188 | 0.01 | 0.01 | -0.00 | sell |
| Engineers Gate Manager LP | 0 | 46,923 | +46,923 | 0.00 | 0.06 | +0.06 | buy |
| NEW YORK STATE TEACHERS RETIREMENT SYSTEM | 48,243 | 46,372 | -1,871 | 0.01 | 0.01 | -0.00 | sell |
| DnB Asset Management AS | 82,320 | 46,367 | -35,953 | 0.03 | 0.02 | -0.01 | sell |
| CANADA PENSION PLAN INVESTMENT BOARD | 51,600 | 43,900 | -7,700 | 0.00 | 0.00 | -0.00 | sell |
| FIRST TRUST ADVISORS LP | 1,956 | 42,754 | +40,798 | 0.00 | 0.00 | +0.00 | buy |
| STATE OF WISCONSIN INVESTMENT BOARD | 39,141 | 38,362 | -779 | 0.01 | 0.01 | -0.00 | sell |
| THRIVENT FINANCIAL FOR LUTHERANS | 39,465 | 38,337 | -1,128 | 0.01 | 0.01 | -0.00 | sell |
| BNP PARIBAS FINANCIAL MARKETS | 19,347 | 36,196 | +16,849 | 0.00 | 0.00 | +0.00 | buy |
| TORONTO DOMINION BANK | 0 | 36,126 | +36,126 | 0.00 | 0.01 | +0.01 | buy |