| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| BlackRock, Inc. | 8,724,474 | 8,655,795 | -68,679 | 0.02 | 0.01 | -0.00 | sell |
| VANGUARD GROUP INC | 6,112,219 | 6,046,520 | -65,699 | 0.01 | 0.01 | -0.00 | sell |
| WELLINGTON MANAGEMENT GROUP LLP | 3,244,404 | 3,580,670 | +336,266 | 0.06 | 0.05 | -0.01 | buy |
| PRIMECAP MANAGEMENT CO/CA/ | 1,827,998 | 2,253,788 | +425,790 | 0.15 | 0.14 | -0.01 | buy |
| STATE STREET CORP | 2,090,365 | 2,104,362 | +13,997 | 0.01 | 0.01 | -0.00 | buy |
| AMERIPRISE FINANCIAL INC | 1,999,252 | 1,900,284 | -98,968 | 0.05 | 0.04 | -0.02 | sell |
| ALLIANCEBERNSTEIN L.P. | 1,251,854 | 1,733,474 | +481,620 | 0.04 | 0.04 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 1,330,593 | 1,316,087 | -14,506 | 0.01 | 0.01 | -0.00 | sell |
| WESTFIELD CAPITAL MANAGEMENT CO LP | 1,167,853 | 1,231,641 | +63,788 | 0.51 | 0.42 | -0.08 | buy |
| WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC | 1,136,095 | 1,093,744 | -42,351 | 0.31 | 0.23 | -0.08 | sell |
| JANUS HENDERSON GROUP PLC | 1,087,194 | 1,065,209 | -21,985 | 0.06 | 0.04 | -0.02 | sell |
| MILLENNIUM MANAGEMENT LLC | 0 | 913,410 | +913,410 | 0.00 | 0.06 | +0.06 | buy |
| Capital World Investors | 850,893 | 850,893 | 0 | 0.01 | 0.01 | -0.00 | hold |
| BRAIDWELL LP | 603,414 | 780,164 | +176,750 | 2.13 | 1.89 | -0.24 | buy |
| BROWN CAPITAL MANAGEMENT LLC | 1,139,119 | 762,760 | -376,359 | 3.42 | 2.56 | -0.86 | sell |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 700,458 | 702,380 | +1,922 | 0.01 | 0.01 | -0.00 | buy |
| Point72 Asset Management, L.P. | 719,262 | 690,723 | -28,539 | 0.18 | 0.12 | -0.05 | sell |
| JPMORGAN CHASE & CO | 642,437 | 670,083 | +27,646 | 0.00 | 0.00 | -0.00 | buy |
| NORTHERN TRUST CORP | 635,012 | 627,660 | -7,352 | 0.01 | 0.01 | -0.00 | sell |
| Invesco Ltd. | 997,092 | 607,442 | -389,650 | 0.02 | 0.01 | -0.01 | sell |
| MACQUARIE GROUP LTD | 73,834 | 600,228 | +526,394 | 0.01 | 0.06 | +0.05 | buy |
| RIVERBRIDGE PARTNERS LLC | 403,971 | 569,644 | +165,673 | 0.67 | 0.78 | +0.11 | buy |
| Holocene Advisors, LP | 1,045,886 | 547,052 | -498,834 | 0.27 | 0.10 | -0.16 | sell |
| Capital International Investors | 246,539 | 511,510 | +264,971 | 0.00 | 0.01 | +0.00 | buy |
| BANK OF AMERICA CORP /DE/ | 285,646 | 474,930 | +189,284 | 0.00 | 0.00 | +0.00 | buy |
| Clearbridge Investments, LLC | 478,792 | 471,552 | -7,240 | 0.04 | 0.03 | -0.01 | sell |
| AustralianSuper Pty Ltd | 406,096 | 449,846 | +43,750 | 0.21 | 0.17 | -0.04 | buy |
| LOOMIS SAYLES & CO L P | 593,612 | 447,429 | -146,183 | 0.08 | 0.04 | -0.03 | sell |
| GOLDMAN SACHS GROUP INC | 560,920 | 436,967 | -123,953 | 0.01 | 0.01 | -0.00 | sell |
| MORGAN STANLEY | 496,318 | 429,578 | -66,740 | 0.00 | 0.00 | -0.00 | sell |
| T. Rowe Price Investment Management, Inc. | 0 | 395,653 | +395,653 | 0.00 | 0.02 | +0.02 | buy |
| Bank of New York Mellon Corp | 392,542 | 381,394 | -11,148 | 0.01 | 0.01 | -0.00 | sell |
| ROYAL BANK OF CANADA | 196,375 | 369,439 | +173,064 | 0.00 | 0.01 | +0.00 | buy |
| Qube Research & Technologies Ltd | 196,365 | 367,528 | +171,163 | 0.03 | 0.04 | +0.01 | buy |
| Champlain Investment Partners, LLC | 363,026 | 358,419 | -4,607 | 0.26 | 0.22 | -0.04 | sell |
| Iron Triangle Partners LP | 271,163 | 342,804 | +71,641 | 4.43 | 3.98 | -0.46 | buy |
| GILDER GAGNON HOWE & CO LLC | 700,634 | 334,532 | -366,102 | 0.77 | 0.28 | -0.49 | sell |
| MARSHALL WACE, LLP | 230,685 | 324,527 | +93,842 | 0.03 | 0.03 | +0.00 | buy |
| FRED ALGER MANAGEMENT, LLC | 425,974 | 316,804 | -109,170 | 0.20 | 0.10 | -0.10 | sell |
| Sofinnova Investments, Inc. | 0 | 312,994 | +312,994 | 0.00 | 1.57 | +1.57 | buy |
| JANE STREET GROUP, LLC | 86,171 | 307,183 | +221,012 | 0.01 | 0.03 | +0.01 | buy |
| Artisan Partners Limited Partnership | 287,221 | 293,665 | +6,444 | 0.04 | 0.03 | -0.01 | buy |
| EVENTIDE ASSET MANAGEMENT, LLC | 220,740 | 289,275 | +68,535 | 0.40 | 0.39 | -0.01 | buy |
| D. E. Shaw & Co., Inc. | 0 | 278,435 | +278,435 | 0.00 | 0.02 | +0.02 | buy |
| PRINCIPAL FINANCIAL GROUP INC | 283,390 | 277,202 | -6,188 | 0.02 | 0.01 | -0.00 | sell |
| Allspring Global Investments Holdings, LLC | 280,815 | 267,498 | -13,317 | 0.05 | 0.04 | -0.01 | sell |
| Freestone Grove Partners LP | 219,810 | 263,889 | +44,079 | 0.17 | 0.16 | -0.01 | buy |
| DIMENSIONAL FUND ADVISORS LP | 333,835 | 241,680 | -92,155 | 0.01 | 0.00 | -0.00 | sell |
| COMERICA BANK | 225,190 | 241,646 | +16,456 | 0.09 | 0.07 | -0.02 | buy |
| Rhenman & Partners Asset Management AB | 235,000 | 230,000 | -5,000 | 3.07 | 2.08 | -0.99 | sell |
| PUBLIC SECTOR PENSION INVESTMENT BOARD | 194,842 | 223,708 | +28,866 | 0.09 | 0.07 | -0.02 | buy |
| Atika Capital Management LLC | 319,500 | 212,400 | -107,100 | 3.45 | 1.48 | -1.97 | sell |
| Squarepoint Ops LLC | 297,148 | 210,814 | -86,334 | 0.07 | 0.04 | -0.03 | sell |
| UBS Group AG | 152,840 | 210,093 | +57,253 | 0.00 | 0.00 | +0.00 | buy |
| C WorldWide Group Holding A/S | 162,212 | 207,212 | +45,000 | 0.23 | 0.26 | +0.03 | buy |
| Legal & General Group Plc | 195,211 | 189,276 | -5,935 | 0.01 | 0.00 | -0.00 | sell |
| Amundi | 239,279 | 181,389 | -57,890 | 0.01 | 0.01 | -0.00 | sell |
| Nuveen, LLC | 151,347 | 162,029 | +10,682 | 0.00 | 0.00 | -0.00 | buy |
| RHUMBLINE ADVISERS | 159,283 | 157,697 | -1,586 | 0.01 | 0.01 | -0.00 | sell |
| Assenagon Asset Management S.A. | 12,058 | 157,545 | +145,487 | 0.00 | 0.02 | +0.02 | buy |
| SEI INVESTMENTS CO | 120,755 | 148,108 | +27,353 | 0.01 | 0.01 | -0.00 | buy |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 279,393 | 145,621 | -133,772 | 0.01 | 0.00 | -0.00 | sell |
| KEYBANK NATIONAL ASSOCIATION/OH | 142,675 | 142,447 | -228 | 0.05 | 0.04 | -0.01 | sell |
| OSTERWEIS CAPITAL MANAGEMENT INC | 94,373 | 142,288 | +47,915 | 0.47 | 0.52 | +0.06 | buy |
| Man Group plc | 147,070 | 138,587 | -8,483 | 0.03 | 0.02 | -0.01 | sell |
| Granite Investment Partners, LLC | 192,580 | 137,347 | -55,233 | 0.97 | 0.64 | -0.33 | sell |
| VOYA INVESTMENT MANAGEMENT LLC | 108,196 | 128,210 | +20,014 | 0.01 | 0.01 | -0.00 | buy |
| SEGALL BRYANT & HAMILL, LLC | 122,396 | 125,490 | +3,094 | 0.18 | 0.14 | -0.04 | buy |
| FMR LLC | 6,336,619 | 121,406 | -6,215,213 | 0.04 | 0.00 | -0.04 | sell |
| PRICE T ROWE ASSOCIATES INC /MD/ | 107,542 | 116,906 | +9,364 | 0.00 | 0.00 | -0.00 | buy |
| Swiss National Bank | 108,000 | 110,700 | +2,700 | 0.01 | 0.01 | -0.00 | buy |
| RAYMOND JAMES FINANCIAL INC | 114,604 | 107,815 | -6,789 | 0.00 | 0.00 | -0.00 | sell |
| WCM INVESTMENT MANAGEMENT, LLC | 102,870 | 102,887 | +17 | 0.02 | 0.02 | -0.01 | buy |
| SILVERCREST ASSET MANAGEMENT GROUP LLC | 52,615 | 101,447 | +48,832 | 0.04 | 0.05 | +0.02 | buy |
| Integral Health Asset Management, LLC | 50,000 | 100,000 | +50,000 | 0.48 | 0.59 | +0.11 | buy |
| VICTORY CAPITAL MANAGEMENT INC | 122,542 | 97,307 | -25,235 | 0.01 | 0.00 | -0.00 | sell |
| Cubist Systematic Strategies, LLC | 0 | 94,900 | +94,900 | 0.00 | 0.11 | +0.11 | buy |
| BARCLAYS PLC | 109,370 | 91,152 | -18,218 | 0.00 | 0.00 | -0.00 | sell |
| Susquehanna Portfolio Strategies, LLC | 132,713 | 85,204 | -47,509 | 0.30 | 0.11 | -0.19 | sell |
| DnB Asset Management AS | 57,283 | 73,550 | +16,267 | 0.02 | 0.02 | -0.00 | buy |
| CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 68,277 | 72,353 | +4,076 | 0.00 | 0.00 | -0.00 | buy |
| SIT INVESTMENT ASSOCIATES INC | 45,290 | 68,630 | +23,340 | 0.10 | 0.11 | +0.01 | buy |
| TWO SIGMA INVESTMENTS, LP | 0 | 66,939 | +66,939 | 0.00 | 0.01 | +0.01 | buy |
| TWO SIGMA ADVISERS, LP | 0 | 61,700 | +61,700 | 0.00 | 0.01 | +0.01 | buy |
| CANADA LIFE ASSURANCE Co | 60,834 | 61,348 | +514 | 0.01 | 0.01 | -0.00 | buy |
| Baird Financial Group, Inc. | 63,379 | 58,849 | -4,530 | 0.01 | 0.01 | -0.00 | sell |
| Allianz Asset Management GmbH | 64,028 | 58,654 | -5,374 | 0.01 | 0.01 | -0.00 | sell |
| RENAISSANCE TECHNOLOGIES LLC | 0 | 57,892 | +57,892 | 0.00 | 0.01 | +0.01 | buy |
| PRUDENTIAL FINANCIAL INC | 59,372 | 57,647 | -1,725 | 0.01 | 0.01 | -0.00 | sell |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC | 0 | 57,218 | +57,218 | 0.00 | 0.02 | +0.02 | buy |
| EFG Asset Management (North America) Corp. | 55,459 | 56,548 | +1,089 | 0.81 | 0.60 | -0.21 | buy |
| CITADEL ADVISORS LLC | 320,512 | 55,940 | -264,572 | 0.03 | 0.00 | -0.03 | sell |
| Bellevue Group AG | 55,926 | 55,926 | 0 | 0.13 | 0.09 | -0.03 | hold |
| ENVESTNET ASSET MANAGEMENT INC | 48,439 | 55,883 | +7,444 | 0.00 | 0.00 | -0.00 | buy |
| RA CAPITAL MANAGEMENT, L.P. | 0 | 54,180 | +54,180 | 0.00 | 0.05 | +0.05 | buy |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 50,854 | 53,784 | +2,930 | 0.01 | 0.00 | -0.00 | buy |
| NEW YORK STATE COMMON RETIREMENT FUND | 387,901 | 52,174 | -335,727 | 0.05 | 0.01 | -0.05 | sell |
| Neuberger Berman Group LLC | 41,810 | 50,801 | +8,991 | 0.00 | 0.00 | -0.00 | buy |
| INTECH INVESTMENT MANAGEMENT LLC | 49,316 | 50,095 | +779 | 0.05 | 0.04 | -0.01 | buy |
| THORNBURG INVESTMENT MANAGEMENT INC | 50,430 | 49,069 | -1,361 | 0.07 | 0.05 | -0.01 | sell |